SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wxo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 4wxo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 VAL A 386
ALA A 427
LEU A 443
PHE A 428
 None
 1.17A 1q97B-4wxoA:
undetectable		 1q97B-4wxoA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4wxo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A 368
HIS A 371
VAL A 438
 None
 0.72A 3elzB-4wxoA:
undetectable		 3elzB-4wxoA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4wxo UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 363
SER A 442
GLU A 403
ASP A 464
 None
 1.31A 4blvA-4wxoA:
undetectable		 4blvA-4wxoA:
24.32