SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wxw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4wxw UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 361
PHE A 405
THR A 329
ALA A 387
 None
 1.00A 3ax9B-4wxwA:
undetectable		 3ax9B-4wxwA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 4wxw UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 8 ALA A 414
LEU A 449
GLU A 483
GLU A 418
ALA A 480
 None
 1.12A 3r9tA-4wxwA:
undetectable		 3r9tA-4wxwA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 4wxw UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 8 ALA A 414
LEU A 449
GLU A 483
GLU A 418
ALA A 480
 None
 1.37A 3r9tA-4wxwA:
undetectable		 3r9tA-4wxwA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 4wxw UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 ALA A 414
GLU A 483
GLU A 418
ALA A 480
 None
 1.16A 3r9tC-4wxwA:
undetectable		 3r9tC-4wxwA:
26.59