SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wy8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A  89
GLY A  90
GLY A  91
SER A 164
HIS A 291
 None
 0.27A 1dx6A-4wy8A:
18.9		 1dx6A-4wy8A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.08A 1dz4A-4wy8A:
undetectable		 1dz4A-4wy8A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.08A 1dz4B-4wy8A:
undetectable		 1dz4B-4wy8A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 8 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.05A 1dz9A-4wy8A:
undetectable		 1dz9A-4wy8A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A  90
SER A 164
PHE A 221
TYR A 212
HIS A 291
 None
 0.90A 1maaA-4wy8A:
17.5		 1maaA-4wy8A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A  90
SER A 164
TRP A 220
TYR A 212
HIS A 291
 None
 1.39A 1maaA-4wy8A:
17.5		 1maaA-4wy8A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A  90
SER A 164
PHE A 221
TYR A 212
HIS A 291
 None
 1.05A 1maaC-4wy8A:
19.3		 1maaC-4wy8A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A  90
SER A 164
TRP A 220
TYR A 212
HIS A 291
 None
 1.40A 1maaC-4wy8A:
19.3		 1maaC-4wy8A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 11 GLY A  90
GLY A  91
SER A 164
LEU A 217
HIS A 291
 None
 0.88A 1mx1A-4wy8A:
18.7		 1mx1A-4wy8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A  90
GLY A  91
SER A 164
LEU A 217
HIS A 291
 None
 0.83A 1mx1F-4wy8A:
18.5		 1mx1F-4wy8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 5 SER A 234
PHE A 222
VAL A 172
PHE A 236
 None
 1.45A 1oipA-4wy8A:
2.6		 1oipA-4wy8A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A  89
GLY A  90
GLY A  91
SER A 164
HIS A 291
 None
 0.28A 1qtiA-4wy8A:
4.1		 1qtiA-4wy8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 7 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.04A 1t85A-4wy8A:
undetectable		 1t85A-4wy8A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 5 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.11A 1t88B-4wy8A:
undetectable		 1t88B-4wy8A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A  89
GLY A  90
GLY A  91
SER A 164
HIS A 291
 None
 0.27A 1w6rA-4wy8A:
5.1		 1w6rA-4wy8A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A  89
GLY A  91
SER A 164
PHE A 221
HIS A 291
 None
 0.98A 1w6rA-4wy8A:
5.1		 1w6rA-4wy8A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 9 GLY A  89
GLY A  90
SER A 164
ALA A 165
HIS A 291
 None
 0.92A 2aceA-4wy8A:
5.1		 2aceA-4wy8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		6 / 9 GLY A  90
GLY A  91
SER A 164
ALA A 165
PHE A 221
HIS A 291
 None
 0.86A 2aceA-4wy8A:
5.1		 2aceA-4wy8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 11 GLY A 288
ILE A  14
GLY A 303
ILE A 306
ILE A 290
 None
 0.96A 2b60B-4wy8A:
undetectable		 2b60B-4wy8A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 7 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 0.99A 2cppA-4wy8A:
undetectable		 2cppA-4wy8A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.07A 2feuA-4wy8A:
undetectable		 2feuA-4wy8A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 7 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.03A 2feuB-4wy8A:
undetectable		 2feuB-4wy8A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 8 GLY A  90
GLY A  91
ALA A 165
PHE A 221
HIS A 291
 None
 0.92A 2ha4A-4wy8A:
19.1		 2ha4A-4wy8A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 7 GLY A  90
GLY A  91
ALA A 165
PHE A 221
HIS A 291
 None
 0.94A 2ha4B-4wy8A:
19.4		 2ha4B-4wy8A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 5 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.08A 2m56A-4wy8A:
undetectable		 2m56A-4wy8A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.16A 2zawA-4wy8A:
undetectable		 2zawA-4wy8A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.09A 2zuiA-4wy8A:
undetectable		 2zuiA-4wy8A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 7 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.03A 3fwfA-4wy8A:
undetectable		 3fwfA-4wy8A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.05A 3fwgA-4wy8A:
undetectable		 3fwgA-4wy8A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 7 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.06A 3fwgB-4wy8A:
undetectable		 3fwgB-4wy8A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 7 ILE A 191
TYR A 192
THR A 257
GLY A 292
 None
 0.93A 3gssB-4wy8A:
undetectable		 3gssB-4wy8A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 7 GLY A  89
GLY A  90
SER A 164
LEU A 217
HIS A 291
 None
 1.23A 3o9mA-4wy8A:
4.3		 3o9mA-4wy8A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 7 GLY A  90
GLY A  91
SER A 164
LEU A 217
HIS A 291
 None
 1.39A 3o9mA-4wy8A:
4.3		 3o9mA-4wy8A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 6 GLY A  89
GLY A  90
SER A 164
LEU A 217
HIS A 291
 None
 1.25A 3o9mB-4wy8A:
8.5		 3o9mB-4wy8A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 6 GLY A  90
GLY A  91
SER A 164
LEU A 217
HIS A 291
 None
 1.41A 3o9mB-4wy8A:
8.5		 3o9mB-4wy8A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 LEU A 107
GLY A 292
THR A 103
LEU A 307
GLY A  90
 None
 0.89A 3uq6A-4wy8A:
4.1		 3uq6A-4wy8A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.06A 3wrhE-4wy8A:
undetectable		 3wrhE-4wy8A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.04A 3wrjE-4wy8A:
undetectable		 3wrjE-4wy8A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 7 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.05A 3wrmF-4wy8A:
undetectable		 3wrmF-4wy8A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 LEU A 107
GLY A 292
THR A 103
LEU A 307
GLY A  90
 None
 0.89A 4dc3A-4wy8A:
4.0		 4dc3A-4wy8A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 LEU A 107
GLY A 292
THR A 103
LEU A 307
GLY A  90
 None
 0.90A 4dc3B-4wy8A:
2.5		 4dc3B-4wy8A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.03A 4ek1A-4wy8A:
undetectable		 4ek1A-4wy8A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		6 / 12 GLY A  89
GLY A  90
GLY A  91
SER A 164
TYR A 212
HIS A 291
 None
 0.62A 4ey6A-4wy8A:
19.5		 4ey6A-4wy8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		6 / 12 GLY A  89
GLY A  91
SER A 164
PHE A 221
TYR A 212
HIS A 291
 None
 0.92A 4ey6A-4wy8A:
19.5		 4ey6A-4wy8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		7 / 12 GLY A  89
GLY A  90
GLY A  91
SER A 164
PHE A 221
TYR A 212
HIS A 291
 None
 0.91A 4ey6B-4wy8A:
16.9		 4ey6B-4wy8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		6 / 11 GLY A  90
SER A 164
TRP A 220
TYR A 212
HIS A 291
GLY A 292
 None
 1.43A 4ey7A-4wy8A:
19.5		 4ey7A-4wy8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		6 / 11 GLY A  90
SER A 164
TRP A 220
TYR A 212
HIS A 291
GLY A 292
 None
 1.45A 4ey7B-4wy8A:
19.3		 4ey7B-4wy8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 11 GLY A  91
SER A 164
TYR A 212
HIS A 291
GLY A 292
 None
 1.15A 4ey7B-4wy8A:
19.3		 4ey7B-4wy8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.06A 4g3rA-4wy8A:
undetectable		 4g3rA-4wy8A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.05A 4g3rB-4wy8A:
undetectable		 4g3rB-4wy8A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.06A 4kkyX-4wy8A:
undetectable		 4kkyX-4wy8A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 5 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.10A 4l49A-4wy8A:
undetectable		 4l49A-4wy8A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.06A 4l4cA-4wy8A:
undetectable		 4l4cA-4wy8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 7 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 1.02A 4l4gA-4wy8A:
undetectable		 4l4gA-4wy8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 12 GLY A 167
ALA A 165
THR A  99
HIS A 100
GLY A  90
 None
 0.81A 4ls7A-4wy8A:
undetectable		 4ls7A-4wy8A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 5 SER A 164
ALA A 165
HIS A 291
MET A 218
 None
 1.21A 5dzkb-4wy8A:
2.5
5dzkp-4wy8A:
undetectable		 5dzkb-4wy8A:
22.94
5dzkp-4wy8A:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 SER A 164
ALA A 165
HIS A 291
MET A 218
 None
 1.22A 5dzkB-4wy8A:
2.4
5dzkP-4wy8A:
undetectable		 5dzkB-4wy8A:
22.94
5dzkP-4wy8A:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 5 SER A 164
ALA A 165
HIS A 291
MET A 218
 None
 1.21A 5dzkc-4wy8A:
undetectable
5dzkq-4wy8A:
undetectable		 5dzkc-4wy8A:
22.94
5dzkq-4wy8A:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 5 SER A 164
ALA A 165
HIS A 291
MET A 218
 None
 1.20A 5dzkf-4wy8A:
2.3
5dzkt-4wy8A:
undetectable		 5dzkf-4wy8A:
22.94
5dzkt-4wy8A:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 6 SER A 164
ALA A 165
HIS A 291
MET A 218
 None
 1.22A 5dzkg-4wy8A:
2.4
5dzku-4wy8A:
undetectable		 5dzkg-4wy8A:
22.94
5dzku-4wy8A:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		5 / 10 ASP A 163
VAL A  93
TYR A 120
LEU A 169
ILE A  38
 None
 1.16A 5hw8C-4wy8A:
undetectable
5hw8H-4wy8A:
undetectable		 5hw8C-4wy8A:
18.61
5hw8H-4wy8A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		4 / 7 PHE A 128
TYR A 225
LEU A 169
VAL A 172
 None
 0.99A 5wk9A-4wy8A:
undetectable		 5wk9A-4wy8A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		3 / 3 TYR A 204
ARG A 215
THR A 214
 None
 1.01A 5z84J-4wy8A:
undetectable		 5z84J-4wy8A:
9.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IEY_A_CLMA401_0
(ESTERASE)		 4wy8 ESTERASE
(Rhizomucor
miehei) 		6 / 11 HIS A 100
ASP A 163
TYR A 212
LEU A 213
HIS A 291
GLY A 292
 None
 0.65A 6ieyA-4wy8A:
37.9
6ieyB-4wy8A:
38.1		 6ieyA-4wy8A:
38.32
6ieyB-4wy8A:
38.32