SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.05A 1c8lA-4wy9A:
undetectable		 1c8lA-4wy9A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.04A 1gfzA-4wy9A:
undetectable		 1gfzA-4wy9A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		5 / 11 LEU A 168
PHE A 193
ALA A 195
VAL A 212
GLN A 165
 None
 1.31A 1hbpA-4wy9A:
undetectable		 1hbpA-4wy9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.08A 1l5qA-4wy9A:
undetectable		 1l5qA-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.08A 1l5qB-4wy9A:
undetectable		 1l5qB-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.07A 1l7xA-4wy9A:
undetectable		 1l7xA-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.07A 1l7xB-4wy9A:
undetectable		 1l7xB-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 8 SER A 319
LEU A 324
TYR A 318
ASP A 293
 None
 0.98A 2ddwA-4wy9A:
undetectable		 2ddwA-4wy9A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 5 PHE A 127
PHE A 134
LEU A 113
PHE A  79
 None
 1.23A 2y69P-4wy9A:
undetectable
2y69W-4wy9A:
undetectable		 2y69P-4wy9A:
22.01
2y69W-4wy9A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 5 PHE A 127
PHE A 134
LEU A 113
PHE A  79
 None
 1.19A 3abmP-4wy9A:
undetectable
3abmW-4wy9A:
undetectable		 3abmP-4wy9A:
22.01
3abmW-4wy9A:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.05A 3dd1A-4wy9A:
undetectable		 3dd1A-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.07A 3dd1B-4wy9A:
undetectable		 3dd1B-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.07A 3ddsA-4wy9A:
undetectable		 3ddsA-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.06A 3ddsB-4wy9A:
undetectable		 3ddsB-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.07A 3ddwA-4wy9A:
undetectable		 3ddwA-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.07A 3ddwB-4wy9A:
undetectable		 3ddwB-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 6 THR A  99
ILE A 213
SER A  72
LEU A  75
 None
 0.67A 3deuB-4wy9A:
undetectable		 3deuB-4wy9A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		5 / 12 MET A 136
LEU A 111
GLY A 211
MET A  78
LEU A  87
 None
 1.43A 3h52A-4wy9A:
undetectable		 3h52A-4wy9A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 8 SER A 106
PHE A 100
ASN A 107
ASP A 140
 None
 1.28A 3n66B-4wy9A:
undetectable		 3n66B-4wy9A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		4 / 5 PHE A 127
ILE A  89
PHE A 120
PHE A 134
 None
 1.13A 3owxB-4wy9A:
undetectable		 3owxB-4wy9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_C_NCAC302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		5 / 10 TYR A 274
ASP A 293
ASP A 291
TYR A 287
SER A 295
 None
None
None
ACT  A 401 (-4.5A)
None
 1.47A 3rodC-4wy9A:
undetectable		 3rodC-4wy9A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLN A 232
GLY A 236
ALA A 315
ALA A 297
ALA A 298
 None
 0.94A 3sudA-4wy9A:
undetectable		 3sudA-4wy9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLN A 232
GLY A 236
ALA A 315
ALA A 297
ALA A 298
 None
 0.91A 3sudC-4wy9A:
undetectable		 3sudC-4wy9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLN A 232
GLY A 236
ALA A 315
ALA A 297
ALA A 298
 None
 0.89A 3sudD-4wy9A:
undetectable		 3sudD-4wy9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		5 / 12 LEU A 242
VAL A 240
LEU A  46
ILE A 277
ALA A 276
 None
 1.08A 4ltwA-4wy9A:
undetectable		 4ltwA-4wy9A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		3 / 3 SER A 308
ALA A 310
VAL A 311
 None
 0.52A 4x1iA-4wy9A:
undetectable		 4x1iA-4wy9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		3 / 3 SER A 308
ALA A 310
VAL A 311
 None
 0.54A 5eypA-4wy9A:
undetectable		 5eypA-4wy9A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		3 / 3 SER A 290
ALA A 289
THR A 314
 ACT  A 401 (-2.5A)
ACT  A 401 (-3.5A)
None
 0.55A 5n0xB-4wy9A:
undetectable		 5n0xB-4wy9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLY A 181
SER A  72
LYS A  69
ILE A 167
ASP A 166
 CL  A 402 ( 4.1A)
None
None
None
None
 1.18A 6bxmA-4wy9A:
undetectable		 6bxmA-4wy9A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN
(Campylobacter
jejuni) 		5 / 12 PRO A 117
GLY A 211
GLN A 165
VAL A 164
PHE A  79
 None
 0.96A 6nj9K-4wy9A:
undetectable		 6nj9K-4wy9A:
22.33