SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x09'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4x09 RIBONUCLEASE K6
(Homo
sapiens) 		4 / 8 HIS A  36
ASN A  31
ILE A  30
TRP A  10
 SO4  A 304 ( 3.5A)
None
None
None
 1.44A 3ccfB-4x09A:
undetectable		 3ccfB-4x09A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 4x09 RIBONUCLEASE K6
(Homo
sapiens) 		3 / 3 GLN A 110
THR A   6
ASP A 113
 None
 0.94A 5k9dA-4x09A:
undetectable		 5k9dA-4x09A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 4x09 RIBONUCLEASE K6
(Homo
sapiens) 		3 / 3 THR A  79
HIS A  45
ASN A  77
 None
 0.93A 5n4tA-4x09A:
undetectable		 5n4tA-4x09A:
17.95