SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 9 LEU A 261
ILE A 257
LEU A 117
GLY A 312
ALA A 223
 None
None
None
SCY  A 113 ( 3.1A)
None
 1.26A 1e7aA-4x0oA:
undetectable		 1e7aA-4x0oA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		3 / 3 ALA A  59
VAL A 165
TRP A  11
 None
 0.90A 1gmkA-4x0oA:
undetectable
1gmkB-4x0oA:
undetectable		 1gmkA-4x0oA:
3.51
1gmkB-4x0oA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		3 / 3 ALA A  60
VAL A 165
TRP A  11
 None
 0.81A 1gmkA-4x0oA:
undetectable
1gmkB-4x0oA:
undetectable		 1gmkA-4x0oA:
3.51
1gmkB-4x0oA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		3 / 3 ALA A  60
VAL A 165
TRP A  11
 None
 0.87A 1gmkC-4x0oA:
undetectable
1gmkD-4x0oA:
undetectable		 1gmkC-4x0oA:
3.51
1gmkD-4x0oA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ILE A 257
ASN A 281
GLY A 216
PHE A 220
ALA A 313
 None
SCY  A 113 ( 3.7A)
None
None
SCY  A 113 ( 3.9A)
 1.35A 1hvyB-4x0oA:
undetectable		 1hvyB-4x0oA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 11 ILE A 257
ASN A 281
GLY A 216
PHE A 220
ALA A 313
 None
SCY  A 113 ( 3.7A)
None
None
SCY  A 113 ( 3.9A)
 1.36A 1ju6A-4x0oA:
undetectable		 1ju6A-4x0oA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 10 ILE A 257
ASN A 281
GLY A 216
PHE A 220
ALA A 313
 None
SCY  A 113 ( 3.7A)
None
None
SCY  A 113 ( 3.9A)
 1.36A 1ju6C-4x0oA:
undetectable		 1ju6C-4x0oA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 8 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.06A 1o76B-4x0oA:
undetectable		 1o76B-4x0oA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ARG A  46
LEU A 143
LEU A  15
PRO A  16
LEU A 338
 None
 0.89A 1og5A-4x0oA:
undetectable		 1og5A-4x0oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		6 / 12 ARG A  46
ILE A  47
LEU A 143
LEU A  15
PRO A  16
LEU A 338
 None
 1.24A 1og5B-4x0oA:
undetectable		 1og5B-4x0oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 8 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.04A 1uyuB-4x0oA:
undetectable		 1uyuB-4x0oA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.05A 1yrcA-4x0oA:
undetectable		 1yrcA-4x0oA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 6 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.04A 2feuA-4x0oA:
undetectable		 2feuA-4x0oA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.03A 2feuB-4x0oA:
undetectable		 2feuB-4x0oA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ILE A  47
ALA A  18
ALA A  59
VAL A  58
ASP A 160
 None
 0.98A 2yvlB-4x0oA:
undetectable		 2yvlB-4x0oA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ILE A  47
GLY A 161
ALA A  18
VAL A  58
ASP A 160
 None
 1.11A 2yvlB-4x0oA:
undetectable		 2yvlB-4x0oA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ILE A  47
ALA A  18
ALA A  59
VAL A  58
ASP A 160
 None
 1.00A 2yvlC-4x0oA:
undetectable		 2yvlC-4x0oA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ILE A  47
ALA A  18
ALA A  59
VAL A  58
ASP A 160
 None
 1.01A 2yvlD-4x0oA:
undetectable		 2yvlD-4x0oA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ILE A  47
GLY A 161
ALA A  18
VAL A  58
ASP A 160
 None
 1.15A 2yvlD-4x0oA:
undetectable		 2yvlD-4x0oA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 6 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.08A 2zuiA-4x0oA:
undetectable		 2zuiA-4x0oA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_A_TMQA611_1
(DHFR-TS)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 11 VAL A 165
ALA A  67
ILE A 101
PRO A 102
THR A   9
 None
 1.03A 3clbA-4x0oA:
undetectable		 3clbA-4x0oA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_C_TMQC613_1
(DHFR-TS)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 VAL A 165
ALA A  67
ILE A 101
PRO A 102
THR A   9
 None
 1.01A 3clbC-4x0oA:
undetectable		 3clbC-4x0oA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_D_TMQD614_1
(DHFR-TS)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 10 VAL A 165
ALA A  67
ILE A 101
PRO A 102
THR A   9
 None
 1.01A 3clbD-4x0oA:
undetectable		 3clbD-4x0oA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.03A 3fwfA-4x0oA:
undetectable		 3fwfA-4x0oA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.03A 3fwfB-4x0oA:
undetectable		 3fwfB-4x0oA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.04A 3fwjA-4x0oA:
undetectable		 3fwjA-4x0oA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_C_TMQC613_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 11 VAL A 165
ALA A  67
ILE A 101
PRO A 102
THR A   9
 None
 1.01A 3hbbC-4x0oA:
undetectable		 3hbbC-4x0oA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_D_TMQD614_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 10 VAL A 165
ALA A  67
ILE A 101
PRO A 102
THR A   9
 None
 1.03A 3hbbD-4x0oA:
undetectable		 3hbbD-4x0oA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA703_1
(CARBONIC ANHYDRASE 2)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 5 HIS A 303
TRP A 324
HIS A 321
ASP A 304
 None
 1.45A 3hs4A-4x0oA:
0.0		 3hs4A-4x0oA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ILE A 289
GLY A 163
GLY A 139
ALA A  80
ALA A  60
 None
 1.09A 3jayA-4x0oA:
undetectable		 3jayA-4x0oA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 9 ALA A 179
VAL A 308
ILE A   8
LEU A 291
ILE A 322
 None
 1.33A 3jw3B-4x0oA:
undetectable		 3jw3B-4x0oA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.03A 3l63A-4x0oA:
undetectable		 3l63A-4x0oA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ALA A  67
ILE A 101
PRO A 102
SER A 103
THR A   9
 None
 1.05A 3nrrA-4x0oA:
undetectable		 3nrrA-4x0oA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ALA A  67
ILE A 101
PRO A 102
SER A 103
THR A   9
 None
 1.08A 3nrrB-4x0oA:
undetectable		 3nrrB-4x0oA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_H_LFXH101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 5 SER A 238
GLY A 175
GLU A 326
GLU A   7
 None
 1.34A 3raeB-4x0oA:
undetectable
3raeD-4x0oA:
undetectable		 3raeB-4x0oA:
21.89
3raeD-4x0oA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.02A 3wrhA-4x0oA:
undetectable		 3wrhA-4x0oA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.04A 3wrjA-4x0oA:
undetectable		 3wrjA-4x0oA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.03A 3wrlA-4x0oA:
undetectable		 3wrlA-4x0oA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.01A 3wrlE-4x0oA:
undetectable		 3wrlE-4x0oA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.04A 3wrmA-4x0oA:
undetectable		 3wrmA-4x0oA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 8 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.06A 4l4fA-4x0oA:
undetectable		 4l4fA-4x0oA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.07A 4l4gA-4x0oA:
undetectable		 4l4gA-4x0oA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 10 SER A  53
ALA A 140
CYH A  14
ALA A 162
ILE A 138
 None
 0.98A 4lbgA-4x0oA:
undetectable		 4lbgA-4x0oA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 GLU A 296
GLU A 293
LYS A  13
ARG A  46
TYR A 279
 None
 1.00A 4mwxA-4x0oA:
undetectable		 4mwxA-4x0oA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ASN A 110
GLY A 312
ILE A 190
GLY A 216
PHE A 214
 None
SCY  A 113 ( 3.1A)
None
None
None
 1.20A 4obwA-4x0oA:
undetectable		 4obwA-4x0oA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 ASN A 110
GLY A 312
ILE A 190
GLY A 216
PHE A 214
 None
SCY  A 113 ( 3.1A)
None
None
None
 1.23A 4obwC-4x0oA:
undetectable		 4obwC-4x0oA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA406_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 5 SER A  48
ARG A 142
LEU A  55
ASP A  54
 None
 1.47A 4xdtA-4x0oA:
undetectable		 4xdtA-4x0oA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		3 / 3 GLY A 159
ASP A 160
ASN A  51
 None
 0.57A 5jglA-4x0oA:
undetectable		 5jglA-4x0oA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 LEU A 346
LEU A 349
ALA A 352
LEU A 147
LEU A  29
 None
 1.23A 5mwyA-4x0oA:
undetectable		 5mwyA-4x0oA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 LEU A 136
ALA A 164
ILE A   8
LEU A 167
 None
 0.98A 5te8A-4x0oA:
undetectable		 5te8A-4x0oA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 GLU A 121
ALA A   6
GLY A 175
TYR A   5
 None
 0.80A 5uxdA-4x0oA:
undetectable		 5uxdA-4x0oA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 7 THR A 124
LEU A 167
VAL A 165
VAL A 308
 None
 1.03A 5wk9A-4x0oA:
undetectable		 5wk9A-4x0oA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 VAL A  95
VAL A  79
GLY A 139
THR A 286
LEU A 143
 None
 1.19A 5x24A-4x0oA:
undetectable		 5x24A-4x0oA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 6 HIS A  49
VAL A  58
LEU A  55
GLN A  61
 None
 1.45A 5xdhA-4x0oA:
undetectable
5xdhC-4x0oA:
undetectable		 5xdhA-4x0oA:
12.68
5xdhC-4x0oA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		4 / 6 ARG A 125
LEU A 126
ALA A 105
GLN A 128
 None
 0.96A 6b89B-4x0oA:
undetectable		 6b89B-4x0oA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 4x0o 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3 PROTEIN 2
(Vibrio
cholerae) 		5 / 12 GLY A 182
ILE A 190
LEU A 191
GLY A 314
ALA A 223
 None
 1.11A 6c2mA-4x0oA:
undetectable		 6c2mA-4x0oA:
13.93