SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 4x1v CD2-ASSOCIATED
PROTEIN
(Homo
sapiens) 		3 / 3 GLN A 122
ILE A 120
TYR A 119
 None
 0.68A 1vifA-4x1vA:
4.6		 1vifA-4x1vA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4x1v CD2-ASSOCIATED
PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 141
ILE A 135
ILE A 137
CYH A 113
VAL A 115
 None
 1.23A 2ft9A-4x1vA:
undetectable		 2ft9A-4x1vA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 4x1v CD2-ASSOCIATED
PROTEIN
(Homo
sapiens) 		4 / 6 ILE A 120
PRO A 121
ILE A 135
VAL A 115
 None
 0.97A 4zj8A-4x1vA:
undetectable		 4zj8A-4x1vA:
8.38