SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x27'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JTX_A_CVIA200_0 (HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION)	4x27	FUSOLIN (Entomopoxvirinae)	5 / 12	ILE A 4 ILE A 8 TYR A 3 ILE A 143 ASN A 192	None	1.29A	1jtxA-4x27A: undetectable	1jtxA-4x27A: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_B_30BB500_1 (GENOME POLYPROTEIN)	4x27	FUSOLIN (Entomopoxvirinae)	5 / 12	HIS A 1 GLY A 2 VAL A 221 GLY A 224 PHE A 105	CU A 401 (-3.1A) None None None None	1.04A	3keeB-4x27A: undetectable	3keeB-4x27A: 17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_C_30BC500_1 (GENOME POLYPROTEIN)	4x27	FUSOLIN (Entomopoxvirinae)	5 / 12	HIS A 1 GLY A 2 VAL A 221 GLY A 224 PHE A 105	CU A 401 (-3.1A) None None None None	1.01A	3keeC-4x27A: undetectable	3keeC-4x27A: 17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XJE_A_TOYA202_1 (AADB)	4x27	FUSOLIN (Entomopoxvirinae)	4 / 8	ASP A 347 ASP A 343 ASP A 344 GLU A 340	None	1.05A	4xjeA-4x27A: undetectable	4xjeA-4x27A: 14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JH7_D_6K9D502_0 (TUBULIN BETA-2B CHAIN)	4x27	FUSOLIN (Entomopoxvirinae)	5 / 11	GLN A 208 ASN A 159 VAL A 113 SER A 114 THR A 162	None	1.44A	5jh7D-4x27A: undetectable	5jh7D-4x27A: 20.34

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JTX_A_CVIA200_0","HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION","4x27","FUSOLIN","Entomopoxvirinae",5,"ILE A   4;ILE A   8;TYR A   3;ILE A 143;ASN A 192","None","1.29A","1jtxA-4x27A:undetectable","1jtxA-4x27A:19.88"],["3KEE_B_30BB500_1","GENOME POLYPROTEIN","4x27","FUSOLIN","Entomopoxvirinae",5,"HIS A   1;GLY A   2;VAL A 221;GLY A 224;PHE A 105"," CU A 401 (-3.1A);None;None;None;None","1.04A","3keeB-4x27A:undetectable","3keeB-4x27A:17.34"],["3KEE_C_30BC500_1","GENOME POLYPROTEIN","4x27","FUSOLIN","Entomopoxvirinae",5,"HIS A   1;GLY A   2;VAL A 221;GLY A 224;PHE A 105"," CU A 401 (-3.1A);None;None;None;None","1.01A","3keeC-4x27A:undetectable","3keeC-4x27A:17.34"],["4XJE_A_TOYA202_1","AADB","4x27","FUSOLIN","Entomopoxvirinae",4,"ASP A 347;ASP A 343;ASP A 344;GLU A 340","None","1.05A","4xjeA-4x27A:undetectable","4xjeA-4x27A:14.48"],["5JH7_D_6K9D502_0","TUBULIN BETA-2B CHAIN","4x27","FUSOLIN","Entomopoxvirinae",5,"GLN A 208;ASN A 159;VAL A 113;SER A 114;THR A 162","None","1.44A","5jh7D-4x27A:undetectable","5jh7D-4x27A:20.34"]]