SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x2h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 4x2h PUTATIVE MRNA EXPORT
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 TYR A 406
PRO A 403
ASP A 546
ARG A 526
LEU A 399
 None
 1.20A 1r30A-4x2hA:
undetectable		 1r30A-4x2hA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4x2h PUTATIVE MRNA EXPORT
PROTEIN
SER-SER-VAL-PHE-GLY-
ALA-PRO-ALA
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		3 / 3 ARG A 542
PRO A 491
ASN C  17
 None
 1.06A 5jwaA-4x2hA:
undetectable
5jwaH-4x2hA:
undetectable		 5jwaA-4x2hA:
20.30
5jwaH-4x2hA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4x2h PUTATIVE MRNA EXPORT
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 ASP A 423
GLU A 511
PHE A 412
ARG A 449
ARG A 522
 None
 1.48A 5m54B-4x2hA:
undetectable		 5m54B-4x2hA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4x2h PUTATIVE MRNA EXPORT
PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASP A 419
SER A 427
SER A 430
 None
 0.82A 6mxtA-4x2hA:
undetectable		 6mxtA-4x2hA:
17.69