SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4x2m MTR2
(Chaetomium
thermophilum) 		3 / 3 TRP A 159
HIS A 113
MET A 109
 None
 1.44A 1l5qB-4x2mA:
undetectable		 1l5qB-4x2mA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 4x2m MTR2
(Chaetomium
thermophilum) 		5 / 9 VAL A  12
SER A  10
LEU A 155
ILE A 175
GLY A 129
 None
 1.21A 3cv9A-4x2mA:
undetectable		 3cv9A-4x2mA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4x2m MTR2
(Chaetomium
thermophilum) 		3 / 3 LYS A  38
LEU A 174
ASP A 160
 None
 0.86A 5zv2A-4x2mA:
undetectable		 5zv2A-4x2mA:
14.29