SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x3x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4x3x ACTIVITY-REGULATED
CYTOSKELETON-ASSOCIA
TED PROTEIN
(Rattus
norvegicus) 		5 / 11 LEU A 329
LEU A 337
LEU A 348
ARG A 306
LEU A 302
 None
 1.16A 4wg0I-4x3xA:
undetectable
4wg0J-4x3xA:
undetectable
4wg0K-4x3xA:
undetectable		 4wg0I-4x3xA:
9.30
4wg0J-4x3xA:
9.30
4wg0K-4x3xA:
9.30