SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x4j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		3 / 3 VAL A   5
VAL A 130
TRP A 147
 None
 1.00A 1av2A-4x4jA:
undetectable
1av2B-4x4jA:
undetectable		 1av2A-4x4jA:
3.07
1av2B-4x4jA:
3.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 9 GLY A  19
GLY A  27
ILE A  26
VAL A 149
ILE A   7
 None
 1.02A 1hxwA-4x4jA:
undetectable		 1hxwA-4x4jA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		3 / 3 ALA A 451
VAL A 448
TRP A 386
 None
 0.90A 1micA-4x4jA:
undetectable
1micB-4x4jA:
undetectable		 1micA-4x4jA:
3.07
1micB-4x4jA:
3.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 11 GLU A  32
GLU A 100
LEU A  15
PRO A  12
GLY A 108
 FAD  A 503 (-2.5A)
FAD  A 503 ( 4.9A)
None
FAD  A 503 (-3.9A)
None
 1.35A 1mjqA-4x4jA:
undetectable
1mjqB-4x4jA:
undetectable		 1mjqA-4x4jA:
10.54
1mjqB-4x4jA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 11 GLY A 108
GLU A  32
GLU A 100
LEU A  15
PRO A  12
 None
FAD  A 503 (-2.5A)
FAD  A 503 ( 4.9A)
None
FAD  A 503 (-3.9A)
 1.31A 1mjqA-4x4jA:
undetectable
1mjqB-4x4jA:
undetectable		 1mjqA-4x4jA:
10.54
1mjqB-4x4jA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 10 GLU A  32
GLU A 100
LEU A  15
PRO A  12
GLY A 108
 FAD  A 503 (-2.5A)
FAD  A 503 ( 4.9A)
None
FAD  A 503 (-3.9A)
None
 1.39A 1mjqC-4x4jA:
undetectable
1mjqD-4x4jA:
undetectable		 1mjqC-4x4jA:
10.54
1mjqD-4x4jA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 10 GLY A 108
GLU A  32
GLU A 100
LEU A  15
PRO A  12
 None
FAD  A 503 (-2.5A)
FAD  A 503 ( 4.9A)
None
FAD  A 503 (-3.9A)
 1.33A 1mjqG-4x4jA:
undetectable
1mjqH-4x4jA:
undetectable		 1mjqG-4x4jA:
10.54
1mjqH-4x4jA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 11 LEU A 143
ASP A 125
VAL A 123
GLY A 150
VAL A 134
 None
 0.84A 1t3rB-4x4jA:
undetectable		 1t3rB-4x4jA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 4 GLY A 150
SER A 156
VAL A 162
LEU A 148
 None
 1.35A 1yajB-4x4jA:
undetectable		 1yajB-4x4jA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 12 LEU A 143
VAL A 123
GLY A 150
VAL A 134
VAL A 132
 None
 0.69A 2ieoB-4x4jA:
undetectable		 2ieoB-4x4jA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 11 LEU A 143
VAL A 123
GLY A 150
VAL A 134
VAL A 132
 None
 0.80A 2nnpB-4x4jA:
undetectable		 2nnpB-4x4jA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 7 LEU A 180
PHE A 176
PHE A 229
ILE A 244
 None
 0.92A 2opxA-4x4jA:
undetectable		 2opxA-4x4jA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 11 ALA A  10
ILE A   7
ILE A 114
ALA A 107
ALA A  18
 None
 0.88A 2qhfA-4x4jA:
undetectable		 2qhfA-4x4jA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 10 VAL A 149
LEU A  21
ARG A  22
GLY A  19
ALA A 107
 None
 1.03A 2xf3A-4x4jA:
undetectable		 2xf3A-4x4jA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 8 VAL A 149
ARG A  22
GLY A  19
ALA A 107
 None
 0.87A 2xfsA-4x4jA:
undetectable		 2xfsA-4x4jA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 8 VAL A 149
ARG A  22
GLY A  19
ALA A 107
 None
 0.86A 2xh9A-4x4jA:
undetectable		 2xh9A-4x4jA:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 5 LEU A 330
GLN A 286
THR A 333
HIS A 323
 None
 1.11A 2zj0B-4x4jA:
3.1		 2zj0B-4x4jA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 10 GLY A  19
ALA A  18
GLY A  27
VAL A 149
ILE A   7
 None
 0.95A 3ekyA-4x4jA:
undetectable		 3ekyA-4x4jA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 10 GLY A  19
ALA A  18
GLY A  27
VAL A 149
ILE A   7
 None
 0.93A 3em3A-4x4jA:
undetectable		 3em3A-4x4jA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 9 PHE A  74
VAL A  79
VAL A 370
GLN A 286
GLY A  72
 None
 1.46A 3km6B-4x4jA:
undetectable		 3km6B-4x4jA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG201_1
(PROTEIN S100-A4)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 9 GLY A  75
GLY A 285
CYH A 214
ILE A 212
MET A 198
 None
FAD  A 503 (-3.3A)
None
None
None
 1.42A 3ko0F-4x4jA:
undetectable
3ko0G-4x4jA:
undetectable		 3ko0F-4x4jA:
9.27
3ko0G-4x4jA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 10 GLY A  75
GLY A 285
CYH A 214
ILE A 212
MET A 198
 None
FAD  A 503 (-3.3A)
None
None
None
 1.43A 3ko0L-4x4jA:
undetectable
3ko0N-4x4jA:
undetectable		 3ko0L-4x4jA:
9.27
3ko0N-4x4jA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 10 GLY A 285
CYH A 214
ILE A 212
MET A 198
GLY A  75
 FAD  A 503 (-3.3A)
None
None
None
None
 1.43A 3ko0R-4x4jA:
undetectable
3ko0T-4x4jA:
undetectable		 3ko0R-4x4jA:
9.27
3ko0T-4x4jA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 10 LEU A 143
VAL A 123
GLY A 150
VAL A 134
VAL A 132
 None
 0.86A 3nu9B-4x4jA:
undetectable		 3nu9B-4x4jA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 11 LEU A 143
ASP A 125
VAL A 123
GLY A 150
VAL A 134
 None
 0.93A 3oy4A-4x4jA:
undetectable		 3oy4A-4x4jA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		3 / 3 LEU A  60
ARG A 390
ASN A 289
 None
None
FAD  A 503 (-3.4A)
 0.71A 3qxvD-4x4jA:
undetectable		 3qxvD-4x4jA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 12 LEU A 143
ASP A 125
VAL A 123
GLY A 150
VAL A 132
 None
 0.97A 3so9B-4x4jA:
undetectable		 3so9B-4x4jA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		3 / 3 ARG A 159
PHE A 166
PRO A 167
 None
 0.70A 3zoaB-4x4jA:
undetectable		 3zoaB-4x4jA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 9 LEU A  17
LEU A 298
GLY A 299
VAL A 306
VAL A 305
 None
 1.20A 4c9kB-4x4jA:
undetectable		 4c9kB-4x4jA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 10 LEU A  17
LEU A 298
GLY A 299
VAL A 306
VAL A 305
 None
 1.15A 4c9nB-4x4jA:
undetectable		 4c9nB-4x4jA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 6 PHE A 176
ALA A 235
ALA A 218
PRO A 219
 None
 0.79A 4dtzA-4x4jA:
undetectable		 4dtzA-4x4jA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		3 / 3 TYR A 377
HIS A 462
ARG A 458
 None
 1.02A 4e7bC-4x4jA:
undetectable		 4e7bC-4x4jA:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 6 THR A 333
GLY A 284
PRO A 282
GLY A 256
 None
None
FAD  A 503 (-4.5A)
None
 0.79A 4fjpA-4x4jA:
undetectable		 4fjpA-4x4jA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 7 ILE A 212
GLY A  76
ALA A 283
GLN A 347
 None
 0.81A 4g0uB-4x4jA:
undetectable		 4g0uB-4x4jA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 12 ILE A 292
THR A  50
THR A  99
ALA A  91
PHE A  63
 None
 1.38A 4pbhA-4x4jA:
undetectable		 4pbhA-4x4jA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		3 / 4 ARG A  33
GLY A 117
GLU A  32
 FAD  A 503 (-3.4A)
None
FAD  A 503 (-2.5A)
 0.60A 4z2dB-4x4jA:
undetectable
4z2dC-4x4jA:
undetectable		 4z2dB-4x4jA:
24.73
4z2dC-4x4jA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 5 GLY A 207
ARG A 181
GLY A 182
GLU A 248
 None
 1.15A 4z2eB-4x4jA:
undetectable
4z2eC-4x4jA:
undetectable		 4z2eB-4x4jA:
24.73
4z2eC-4x4jA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		3 / 3 TRP A 106
ARG A  57
LEU A  21
 None
 0.98A 5dbyA-4x4jA:
undetectable		 5dbyA-4x4jA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 12 LEU A 271
LEU A 315
ILE A  26
LEU A  17
ALA A 304
 None
 1.09A 5og9B-4x4jA:
undetectable		 5og9B-4x4jA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 12 ALA A 273
GLY A 274
LEU A  17
LEU A 302
ARG A 159
 None
FAD  A 503 (-3.3A)
None
None
None
 1.17A 5w7pA-4x4jA:
undetectable		 5w7pA-4x4jA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 12 ALA A 441
PRO A 402
SER A 404
PRO A 443
PHE A 419
 None
None
SO4  A 501 ( 3.8A)
None
None
 1.29A 5zvgB-4x4jA:
2.7		 5zvgB-4x4jA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 12 LEU A 143
VAL A 123
GLY A 150
VAL A 134
VAL A 132
 None
 0.81A 6dh0A-4x4jA:
undetectable		 6dh0A-4x4jA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 6 TRP A 147
TRP A 300
ALA A 303
LEU A 302
 None
 0.88A 6fosA-4x4jA:
undetectable		 6fosA-4x4jA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		4 / 5 THR A  47
THR A 333
HIS A 280
GLY A  43
 None
None
None
FAD  A 503 (-3.2A)
 0.96A 6gbnC-4x4jA:
3.0		 6gbnC-4x4jA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 12 GLY A  76
GLY A  75
VAL A 370
ASN A 332
GLY A 284
 None
 1.08A 6gneA-4x4jA:
2.8		 6gneA-4x4jA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 4x4j PUTATIVE OXYGENASE
(Amycolatopsis
orientalis) 		5 / 12 GLY A  76
GLY A  75
VAL A 370
ASN A 332
GLY A 284
 None
 1.08A 6gneB-4x4jA:
2.7		 6gneB-4x4jA:
22.79