SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x54'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 4x54 OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Brucella
ovis) 		4 / 5 LEU A 106
ASN A 108
VAL A 205
ALA A 147
 None
 1.22A 2cizA-4x54A:
undetectable		 2cizA-4x54A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 4x54 OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Brucella
ovis) 		4 / 6 LEU A 103
LEU A 154
ILE A  92
ARG A  93
 None
 0.76A 2rlfC-4x54A:
undetectable
2rlfD-4x54A:
undetectable		 2rlfC-4x54A:
11.64
2rlfD-4x54A:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4x54 OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Brucella
ovis) 		4 / 7 LEU A 150
VAL A  30
THR A  32
VAL A  77
 None
 0.95A 2zaxA-4x54A:
undetectable		 2zaxA-4x54A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4x54 OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Brucella
ovis) 		4 / 7 LEU A 150
VAL A  30
THR A  32
VAL A  77
 None
 0.95A 3fwgB-4x54A:
undetectable		 3fwgB-4x54A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4x54 OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Brucella
ovis) 		4 / 7 LEU A 150
VAL A  30
THR A  32
VAL A  77
 None
 0.96A 3fwiA-4x54A:
undetectable		 3fwiA-4x54A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 4x54 OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Brucella
ovis) 		4 / 4 VAL A  77
ILE A  89
ASN A 108
VAL A  30
 None
 1.09A 5ajqA-4x54A:
undetectable		 5ajqA-4x54A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4x54 OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Brucella
ovis) 		5 / 12 VAL A 161
ILE A  75
LEU A  79
VAL A  77
ILE A  85
 None
 0.95A 5mugA-4x54A:
2.2		 5mugA-4x54A:
23.96