SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x5s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 7 HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.23A 1am6A-4x5sA:
29.8		 1am6A-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 8 HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.26A 1azmA-4x5sA:
28.6		 1azmA-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 8 HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.25A 1bzmA-4x5sA:
28.5		 1bzmA-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.26A 1cilA-4x5sA:
29.9		 1cilA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 HIS A  64
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.36A 1cilA-4x5sA:
29.9		 1cilA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  64
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.19A 1cilA-4x5sA:
29.9		 1cilA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.09A 1cilA-4x5sA:
29.9		 1cilA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.41A 1cilA-4x5sA:
29.9		 1cilA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 11 HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.30A 1dmyA-4x5sA:
26.3		 1dmyA-4x5sA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A 108
HIS A  89
HIS A  91
TYR A 169
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-3.3A)
 1.18A 1dmyA-4x5sA:
26.3		 1dmyA-4x5sA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.17A 1dmyB-4x5sA:
26.3		 1dmyB-4x5sA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.32A 1dmyB-4x5sA:
26.3		 1dmyB-4x5sA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A 108
HIS A  89
HIS A  91
TYR A 169
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-3.3A)
 1.16A 1dmyB-4x5sA:
26.3		 1dmyB-4x5sA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 9 GLN A  67
HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.94A 1jd0A-4x5sA:
30.2		 1jd0A-4x5sA:
32.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.44A 1jd0A-4x5sA:
30.2		 1jd0A-4x5sA:
32.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.48A 1jd0A-4x5sA:
30.2		 1jd0A-4x5sA:
32.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 11 GLN A  67
HIS A  89
HIS A  91
GLU A  95
HIS A 108
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.88A 1jd0B-4x5sA:
29.9		 1jd0B-4x5sA:
32.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.19A 1jd0B-4x5sA:
29.9		 1jd0B-4x5sA:
32.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.40A 1jd0B-4x5sA:
29.9		 1jd0B-4x5sA:
32.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  89
HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.10A 1jd0B-4x5sA:
29.9		 1jd0B-4x5sA:
32.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.39A 1jd0B-4x5sA:
29.9		 1jd0B-4x5sA:
32.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 ASN A  62
HIS A  91
LEU A 173
THR A 174
PRO A 177
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.98A 1oq5A-4x5sA:
30.2		 1oq5A-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 174
PRO A 177
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
None
 0.38A 1oq5A-4x5sA:
30.2		 1oq5A-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.15A 1oq5A-4x5sA:
30.2		 1oq5A-4x5sA:
38.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.02A 1rj6A-4x5sA:
30.2		 1rj6A-4x5sA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.38A 1rj6A-4x5sA:
30.2		 1rj6A-4x5sA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.03A 1rj6A-4x5sA:
30.2		 1rj6A-4x5sA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
THR A 175
THR A 174
TRP A   3
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.42A 1rj6A-4x5sA:
30.2		 1rj6A-4x5sA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.01A 1rj6B-4x5sA:
30.1		 1rj6B-4x5sA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.38A 1rj6B-4x5sA:
30.1		 1rj6B-4x5sA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.03A 1rj6B-4x5sA:
30.1		 1rj6B-4x5sA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
THR A 175
THR A 174
TRP A   3
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.42A 1rj6B-4x5sA:
30.1		 1rj6B-4x5sA:
29.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 10 GLN A  87
HIS A  89
HIS A 108
VAL A 110
VAL A 120
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.35A 1ydaA-4x5sA:
29.7		 1ydaA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.10A 1ydbA-4x5sA:
29.9		 1ydbA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.26A 1ydbA-4x5sA:
29.9		 1ydbA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
HIS A  89
VAL A 110
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.38A 1ydbA-4x5sA:
29.9		 1ydbA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.12A 1yddA-4x5sA:
29.9		 1yddA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
THR A 174
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.28A 1yddA-4x5sA:
29.9		 1yddA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.36A 1yddA-4x5sA:
29.9		 1yddA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.26A 1z9yA-4x5sA:
30.0		 1z9yA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.38A 1z9yA-4x5sA:
30.0		 1z9yA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 ASN A  62
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.07A 1zgfA-4x5sA:
30.0		 1zgfA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.31A 1zgfA-4x5sA:
30.0		 1zgfA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.33A 1zgfA-4x5sA:
30.0		 1zgfA-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 12 GLN A  67
HIS A  89
HIS A  91
GLU A  95
HIS A 108
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.91A 1zsbA-4x5sA:
29.9		 1zsbA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.18A 1zsbA-4x5sA:
29.9		 1zsbA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
None
 1.49A 1zsbA-4x5sA:
29.9		 1zsbA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.32A 1zsbA-4x5sA:
29.9		 1zsbA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.48A 1zsbA-4x5sA:
29.9		 1zsbA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.39A 1zsbA-4x5sA:
29.9		 1zsbA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.30A 2aw1A-4x5sA:
30.0		 2aw1A-4x5sA:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.23A 2aw1A-4x5sA:
30.0		 2aw1A-4x5sA:
38.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		3 / 3 THR A 213
PRO A 215
PRO A  31
 None
 0.82A 2d55C-4x5sA:
undetectable		 2d55C-4x5sA:
10.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 6 TRP A   3
GLN A  87
THR A 175
PRO A 177
 None
AZM  A 302 (-4.3A)
AZM  A 302 (-3.3A)
None
 0.51A 2ez7A-4x5sA:
29.6		 2ez7A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 8 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.28A 2gehA-4x5sA:
29.8		 2gehA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 GLN A  67
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.87A 2h4nA-4x5sA:
29.9		 2h4nA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 9 GLN A  87
HIS A  91
HIS A 108
VAL A 110
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.48A 2h4nA-4x5sA:
29.9		 2h4nA-4x5sA:
38.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 6 ASN A  62
HIS A  64
GLN A  87
THR A 175
 None
None
AZM  A 302 (-4.3A)
AZM  A 302 (-3.3A)
 0.34A 2hkkA-4x5sA:
29.9		 2hkkA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 8 HIS A  89
HIS A  91
HIS A 108
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 0.37A 2it4A-4x5sA:
28.8		 2it4A-4x5sA:
39.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 ASN A  62
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.06A 2pouA-4x5sA:
29.9		 2pouA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.29A 2pouA-4x5sA:
29.9		 2pouA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.31A 2pouA-4x5sA:
29.9		 2pouA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.10A 2pouA-4x5sA:
29.9		 2pouA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.34A 3bl1A-4x5sA:
29.8		 3bl1A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.30A 3bl1A-4x5sA:
29.8		 3bl1A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.31A 3cajA-4x5sA:
30.0		 3cajA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.08A 3cajA-4x5sA:
30.0		 3cajA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 10 HIS A  89
HIS A 108
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 1.43A 3cajA-4x5sA:
30.0		 3cajA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  89
HIS A 108
THR A 174
PRO A 176
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
None
None
 1.28A 3cajA-4x5sA:
30.0		 3cajA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  91
HIS A  89
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.47A 3cajA-4x5sA:
30.0		 3cajA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
 0.88A 3czvA-4x5sA:
29.8
3czvB-4x5sA:
29.9		 3czvA-4x5sA:
35.06
3czvB-4x5sA:
35.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.51A 3czvA-4x5sA:
29.8
3czvB-4x5sA:
29.9		 3czvA-4x5sA:
35.06
3czvB-4x5sA:
35.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
 0.96A 3czvB-4x5sA:
29.9		 3czvB-4x5sA:
35.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.45A 3czvB-4x5sA:
29.9		 3czvB-4x5sA:
35.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.40A 3czvB-4x5sA:
29.9		 3czvB-4x5sA:
35.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 GLN A  67
HIS A  89
HIS A  91
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.08A 3dazA-4x5sA:
30.0		 3dazA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.28A 3dazA-4x5sA:
30.0		 3dazA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.08A 3dazA-4x5sA:
30.0		 3dazA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 12 GLN A  67
HIS A  89
HIS A  91
GLU A  95
HIS A 108
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.92A 3dc3A-4x5sA:
30.0		 3dc3A-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.19A 3dc3A-4x5sA:
30.0		 3dc3A-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.31A 3dc3A-4x5sA:
30.0		 3dc3A-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.48A 3dc3A-4x5sA:
30.0		 3dc3A-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.10A 3dc3A-4x5sA:
30.0		 3dc3A-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.95A 3dcsA-4x5sA:
30.0		 3dcsA-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.35A 3dcsA-4x5sA:
30.0		 3dcsA-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.11A 3dcsA-4x5sA:
30.0		 3dcsA-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.29A 3dcwA-4x5sA:
30.0		 3dcwA-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
PRO A 177
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.10A 3dcwA-4x5sA:
30.0		 3dcwA-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 10 HIS A  89
HIS A 108
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 1.44A 3dcwA-4x5sA:
30.0		 3dcwA-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  89
HIS A 108
THR A 174
PRO A 176
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
None
None
 1.29A 3dcwA-4x5sA:
30.0		 3dcwA-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.39A 3dcwA-4x5sA:
30.0		 3dcwA-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.94A 3dcwA-4x5sA:
30.0		 3dcwA-4x5sA:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.28A 3dd0A-4x5sA:
29.9		 3dd0A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
PRO A 177
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.09A 3dd0A-4x5sA:
29.9		 3dd0A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 10 HIS A  89
HIS A 108
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 1.46A 3dd0A-4x5sA:
29.9		 3dd0A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.39A 3dd0A-4x5sA:
29.9		 3dd0A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.94A 3dd0A-4x5sA:
29.9		 3dd0A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.43A 3f4xA-4x5sA:
29.6		 3f4xA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 ASN A  62
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.05A 3f4xA-4x5sA:
29.6		 3f4xA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.06A 3f4xA-4x5sA:
29.6		 3f4xA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 1.38A 3f4xA-4x5sA:
29.6		 3f4xA-4x5sA:
38.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 THR A 174
LEU A 173
LEU A 160
ILE A 118
ILE A  49
 AZM  A 302 (-3.3A)
AZM  A 302 (-3.7A)
None
PE8  A 303 (-4.9A)
None
 1.02A 3frqB-4x5sA:
undetectable		 3frqB-4x5sA:
21.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
VAL A 110
ILE A 118
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
PE8  A 303 (-4.9A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.47A 3fw3A-4x5sA:
28.3		 3fw3A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 ASN A  62
HIS A  64
HIS A  89
HIS A  91
VAL A 110
ILE A 118
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
PE8  A 303 (-4.9A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.41A 3fw3A-4x5sA:
28.3		 3fw3A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 HIS A  64
GLN A  67
HIS A  89
HIS A  91
LEU A 173
THR A 174
THR A 175
 None
None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.95A 3fw3A-4x5sA:
28.3		 3fw3A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 HIS A  64
GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.25A 3fw3A-4x5sA:
28.3		 3fw3A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 HIS A  64
HIS A  91
ILE A 118
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
PE8  A 303 (-4.9A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.28A 3fw3A-4x5sA:
28.3		 3fw3A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		12 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
ILE A 118
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
PE8  A 303 (-4.9A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.37A 3fw3B-4x5sA:
28.2		 3fw3B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
ILE A 118
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
PE8  A 303 (-4.9A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.41A 3fw3B-4x5sA:
28.2		 3fw3B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
ILE A 118
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
PE8  A 303 (-4.9A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.32A 3fw3B-4x5sA:
28.2		 3fw3B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  91
ILE A 118
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
PE8  A 303 (-4.9A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.27A 3fw3B-4x5sA:
28.2		 3fw3B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 ASN A  62
GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 175
 None
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.36A 3hkuA-4x5sA:
29.8		 3hkuA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 175
TRP A 184
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.31A 3hkuA-4x5sA:
29.8		 3hkuA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.44A 3hkuA-4x5sA:
29.8		 3hkuA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		3 / 3 GLU A  95
HIS A 108
THR A 174
 AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
 0.09A 3hkuA-4x5sA:
29.8		 3hkuA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.25A 3hs4A-4x5sA:
30.2		 3hs4A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.26A 3hs4A-4x5sA:
30.2		 3hs4A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.09A 3hs4A-4x5sA:
30.2		 3hs4A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 7 VAL A  98
LYS A 101
TYR A 103
PRO A 190
 None
 0.64A 3hs4A-4x5sA:
30.2		 3hs4A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.97A 3iaiA-4x5sA:
29.6		 3iaiA-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
 1.21A 3iaiA-4x5sA:
29.6		 3iaiA-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.23A 3iaiA-4x5sA:
29.6		 3iaiA-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 0.97A 3iaiA-4x5sA:
29.6		 3iaiA-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.97A 3iaiB-4x5sA:
30.0		 3iaiB-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
 1.22A 3iaiB-4x5sA:
30.0		 3iaiB-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.22A 3iaiB-4x5sA:
30.0		 3iaiB-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.99A 3iaiC-4x5sA:
29.9		 3iaiC-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
 1.22A 3iaiC-4x5sA:
29.9		 3iaiC-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.21A 3iaiC-4x5sA:
29.9		 3iaiC-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  89
HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.11A 3iaiC-4x5sA:
29.9		 3iaiC-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.98A 3iaiD-4x5sA:
29.9		 3iaiD-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
 1.21A 3iaiD-4x5sA:
29.9		 3iaiD-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.21A 3iaiD-4x5sA:
29.9		 3iaiD-4x5sA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 0.94A 3iaiD-4x5sA:
29.9		 3iaiD-4x5sA:
34.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 8 GLY A  63
MET A 107
PHE A 201
PHE A 138
 None
 0.96A 3ko0D-4x5sA:
undetectable
3ko0E-4x5sA:
undetectable		 3ko0D-4x5sA:
19.90
3ko0E-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 8 PHE A 201
PHE A 138
GLY A  63
MET A 107
 None
 1.01A 3ko0B-4x5sA:
undetectable
3ko0J-4x5sA:
undetectable		 3ko0B-4x5sA:
19.90
3ko0J-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 7 GLY A  63
MET A 107
PHE A 201
PHE A 138
 None
 1.12A 3ko0L-4x5sA:
undetectable
3ko0N-4x5sA:
undetectable		 3ko0L-4x5sA:
19.90
3ko0N-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 7 GLY A  63
MET A 107
PHE A 201
PHE A 138
 None
 0.99A 3ko0M-4x5sA:
undetectable
3ko0P-4x5sA:
undetectable		 3ko0M-4x5sA:
19.90
3ko0P-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 7 PHE A 201
PHE A 138
GLY A  63
MET A 107
 None
 1.04A 3ko0K-4x5sA:
undetectable
3ko0S-4x5sA:
undetectable		 3ko0K-4x5sA:
19.90
3ko0S-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 7 PHE A 201
PHE A 138
GLY A  63
MET A 107
 None
 1.00A 3ko0R-4x5sA:
undetectable
3ko0T-4x5sA:
undetectable		 3ko0R-4x5sA:
19.90
3ko0T-4x5sA:
19.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.42A 3kwaA-4x5sA:
29.6		 3kwaA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  89
HIS A 108
VAL A 120
THR A 174
PRO A 176
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.3A)
None
None
 1.24A 3kwaA-4x5sA:
29.6		 3kwaA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  89
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.09A 3kwaA-4x5sA:
29.6		 3kwaA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 GLN A  67
HIS A  89
HIS A  91
LEU A 173
THR A 174
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 0.88A 3lxeA-4x5sA:
29.1		 3lxeA-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.18A 3lxeA-4x5sA:
29.1		 3lxeA-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.49A 3lxeA-4x5sA:
29.1		 3lxeA-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.49A 3lxeB-4x5sA:
29.2		 3lxeB-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.26A 3mdzA-4x5sA:
29.3		 3mdzA-4x5sA:
35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.99A 3mdzA-4x5sA:
29.3		 3mdzA-4x5sA:
35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.27A 3ml5A-4x5sA:
29.6		 3ml5A-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.21A 3ml5A-4x5sA:
29.6		 3ml5A-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.39A 3ml5A-4x5sA:
29.6		 3ml5A-4x5sA:
37.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 ARG A 219
VAL A  98
GLY A 122
VAL A  32
ILE A  34
 None
 1.07A 3oxvD-4x5sA:
undetectable		 3oxvD-4x5sA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 PRO A 104
ALA A 193
GLN A 197
ILE A 198
PHE A 201
 None
 1.45A 3qelD-4x5sA:
undetectable		 3qelD-4x5sA:
20.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.25A 3v2jA-4x5sA:
30.0		 3v2jA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.24A 3v2jA-4x5sA:
30.0		 3v2jA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.10A 3v2jA-4x5sA:
30.0		 3v2jA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  91
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.07A 3v2mA-4x5sA:
30.1		 3v2mA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.24A 3v2mA-4x5sA:
30.1		 3v2mA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.08A 3v2mA-4x5sA:
30.1		 3v2mA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.38A 3v2mA-4x5sA:
30.1		 3v2mA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 8 GLN A  67
HIS A  89
HIS A  91
THR A 174
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
 0.89A 3w6hA-4x5sA:
28.8		 3w6hA-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 8 GLN A  87
HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.37A 3w6hA-4x5sA:
28.8		 3w6hA-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 GLN A  67
HIS A  89
HIS A  91
GLU A  95
THR A 174
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-3.3A)
 0.83A 3w6hB-4x5sA:
28.8		 3w6hB-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 9 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.38A 3w6hB-4x5sA:
28.8		 3w6hB-4x5sA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.93A 3zncA-4x5sA:
27.4		 3zncA-4x5sA:
32.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.47A 3zncA-4x5sA:
27.4		 3zncA-4x5sA:
32.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.05A 3zncA-4x5sA:
27.4		 3zncA-4x5sA:
32.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 7 LEU A 173
GLU A 106
HIS A 108
HIS A  89
 AZM  A 302 (-3.7A)
None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
 1.27A 4aq7A-4x5sA:
undetectable		 4aq7A-4x5sA:
15.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  91
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.03A 4coqA-4x5sA:
35.7		 4coqA-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.24A 4coqA-4x5sA:
35.7		 4coqA-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.18A 4coqA-4x5sA:
35.7		 4coqA-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.36A 4coqA-4x5sA:
35.7		 4coqA-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.97A 4coqA-4x5sA:
35.7		 4coqA-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.18A 4coqB-4x5sA:
35.5		 4coqB-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.33A 4coqB-4x5sA:
35.5		 4coqB-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.99A 4coqB-4x5sA:
35.5		 4coqB-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.41A 4coqB-4x5sA:
35.5		 4coqB-4x5sA:
49.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 ARG A 219
VAL A  98
GLY A 122
VAL A  32
ILE A  34
 None
 1.10A 4dqcA-4x5sA:
undetectable		 4dqcA-4x5sA:
18.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 10 GLN A  87
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
VAL A 182
TRP A 184
 AZM  A 302 (-4.3A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.49A 4e3hA-4x5sA:
29.8		 4e3hA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 VAL A 120
LEU A 173
THR A 174
THR A 175
VAL A 182
 AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.07A 4e3hA-4x5sA:
29.8		 4e3hA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.95A 4g0cA-4x5sA:
29.9		 4g0cA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.23A 4g0cA-4x5sA:
29.9		 4g0cA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.10A 4g0cA-4x5sA:
29.9		 4g0cA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.13A 4g7aA-4x5sA:
38.0		 4g7aA-4x5sA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
None
 1.47A 4g7aA-4x5sA:
38.0		 4g7aA-4x5sA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.14A 4g7aA-4x5sA:
38.0		 4g7aA-4x5sA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.38A 4g7aA-4x5sA:
38.0		 4g7aA-4x5sA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.15A 4g7aB-4x5sA:
37.9		 4g7aB-4x5sA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
None
 1.49A 4g7aB-4x5sA:
37.9		 4g7aB-4x5sA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.13A 4g7aB-4x5sA:
37.9		 4g7aB-4x5sA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.38A 4g7aB-4x5sA:
37.9		 4g7aB-4x5sA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.11A 4k0sA-4x5sA:
30.0		 4k0sA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.26A 4k0sA-4x5sA:
30.0		 4k0sA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.10A 4k0sA-4x5sA:
30.0		 4k0sA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.98A 4k0sA-4x5sA:
30.0		 4k0sA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.38A 4k0zA-4x5sA:
30.1		 4k0zA-4x5sA:
39.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.10A 4k0zA-4x5sA:
30.1		 4k0zA-4x5sA:
39.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 HIS A  89
HIS A 108
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 1.48A 4k0zA-4x5sA:
30.1		 4k0zA-4x5sA:
39.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.34A 4k0zA-4x5sA:
30.1		 4k0zA-4x5sA:
39.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.26A 4k13A-4x5sA:
30.1		 4k13A-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.25A 4k13A-4x5sA:
30.1		 4k13A-4x5sA:
38.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 ARG A 219
VAL A  98
GLY A 122
VAL A  32
ILE A  34
 None
 1.24A 4ll3B-4x5sA:
undetectable		 4ll3B-4x5sA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.99A 4lu3A-4x5sA:
29.8		 4lu3A-4x5sA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.28A 4lu3A-4x5sA:
29.8		 4lu3A-4x5sA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  89
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.50A 4lu3A-4x5sA:
29.8		 4lu3A-4x5sA:
28.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.41A 4m2rA-4x5sA:
30.0		 4m2rA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.27A 4m2rA-4x5sA:
30.0		 4m2rA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
PRO A 177
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.09A 4m2rA-4x5sA:
30.0		 4m2rA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 1.31A 4m2rA-4x5sA:
30.0		 4m2rA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.97A 4m2rA-4x5sA:
30.0		 4m2rA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 TRP A   3
GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.34A 4m2uA-4x5sA:
30.0		 4m2uA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 TRP A   3
HIS A  64
GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.38A 4m2uA-4x5sA:
30.0		 4m2uA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 TRP A   3
HIS A  64
HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 None
None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.36A 4m2uA-4x5sA:
30.0		 4m2uA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 TRP A   3
HIS A  64
HIS A  89
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.47A 4m2uA-4x5sA:
30.0		 4m2uA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 TRP A   3
HIS A  64
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.20A 4m2uA-4x5sA:
30.0		 4m2uA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 12 TRP A  14
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 175
TRP A 184
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.44A 4m2uA-4x5sA:
30.0		 4m2uA-4x5sA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.23A 4m2vA-4x5sA:
30.0		 4m2vA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
GLY A 116
LEU A 173
THR A 174
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
None
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.13A 4m2vA-4x5sA:
30.0		 4m2vA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.26A 4m2vA-4x5sA:
30.0		 4m2vA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
GLY A 116
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
None
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.12A 4m2vA-4x5sA:
30.0		 4m2vA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
GLY A 116
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
None
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.44A 4m2vA-4x5sA:
30.0		 4m2vA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.23A 4m2wA-4x5sA:
30.0		 4m2wA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.24A 4m2wA-4x5sA:
30.0		 4m2wA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.37A 4m2wA-4x5sA:
30.0		 4m2wA-4x5sA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 8 GLN A  67
HIS A  89
HIS A  91
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.12A 4n16A-4x5sA:
30.1		 4n16A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 8 GLN A  87
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.28A 4n16A-4x5sA:
30.1		 4n16A-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.31A 4pxxA-4x5sA:
30.2		 4pxxA-4x5sA:
39.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
VAL A 110
VAL A 120
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.3A)
None
 0.34A 4twlA-4x5sA:
31.0		 4twlA-4x5sA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
VAL A 110
VAL A 120
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.3A)
None
 0.30A 4twlB-4x5sA:
31.5		 4twlB-4x5sA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.17A 4uovA-4x5sA:
35.2		 4uovA-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.16A 4uovA-4x5sA:
35.2		 4uovA-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.15A 4uovB-4x5sA:
35.2		 4uovB-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.14A 4uovB-4x5sA:
35.2		 4uovB-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.17A 4uovC-4x5sA:
35.1		 4uovC-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
 1.27A 4uovC-4x5sA:
35.1		 4uovC-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.16A 4uovC-4x5sA:
35.1		 4uovC-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.16A 4uovD-4x5sA:
35.2		 4uovD-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.15A 4uovD-4x5sA:
35.2		 4uovD-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.17A 4uovE-4x5sA:
35.1		 4uovE-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.14A 4uovE-4x5sA:
35.1		 4uovE-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.16A 4uovF-4x5sA:
35.3		 4uovF-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.16A 4uovF-4x5sA:
35.3		 4uovF-4x5sA:
49.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.21A 4xiwA-4x5sA:
29.1
4xiwH-4x5sA:
28.9		 4xiwA-4x5sA:
37.25
4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
None
 1.45A 4xiwA-4x5sA:
29.1
4xiwH-4x5sA:
28.9		 4xiwA-4x5sA:
37.25
4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.28A 4xiwA-4x5sA:
29.1
4xiwH-4x5sA:
28.9		 4xiwA-4x5sA:
37.25
4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.00A 4xiwA-4x5sA:
29.1
4xiwH-4x5sA:
28.9		 4xiwA-4x5sA:
37.25
4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.99A 4xiwA-4x5sA:
29.1
4xiwH-4x5sA:
28.9		 4xiwA-4x5sA:
37.25
4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  67
HIS A  89
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.10A 4xiwB-4x5sA:
29.0
4xiwE-4x5sA:
29.3		 4xiwB-4x5sA:
37.25
4xiwE-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.22A 4xiwB-4x5sA:
29.0
4xiwE-4x5sA:
29.3		 4xiwB-4x5sA:
37.25
4xiwE-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.11A 4xiwB-4x5sA:
29.0
4xiwE-4x5sA:
29.3		 4xiwB-4x5sA:
37.25
4xiwE-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.21A 4xiwC-4x5sA:
29.1		 4xiwC-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
None
 1.37A 4xiwC-4x5sA:
29.1		 4xiwC-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.29A 4xiwC-4x5sA:
29.1		 4xiwC-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.01A 4xiwC-4x5sA:
29.1		 4xiwC-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.18A 4xiwD-4x5sA:
29.4		 4xiwD-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
None
 1.41A 4xiwD-4x5sA:
29.4		 4xiwD-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.23A 4xiwD-4x5sA:
29.4		 4xiwD-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.37A 4xiwD-4x5sA:
29.4		 4xiwD-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.23A 4xiwE-4x5sA:
29.2		 4xiwE-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
None
 1.45A 4xiwE-4x5sA:
29.2		 4xiwE-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.22A 4xiwE-4x5sA:
29.2		 4xiwE-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.95A 4xiwE-4x5sA:
29.2		 4xiwE-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.20A 4xiwF-4x5sA:
29.0		 4xiwF-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
None
 1.49A 4xiwF-4x5sA:
29.0		 4xiwF-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.22A 4xiwF-4x5sA:
29.0		 4xiwF-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  89
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.49A 4xiwF-4x5sA:
29.0		 4xiwF-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.39A 4xiwF-4x5sA:
29.0		 4xiwF-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.29A 4xiwG-4x5sA:
29.0		 4xiwG-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.39A 4xiwG-4x5sA:
29.0		 4xiwG-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.38A 4xiwG-4x5sA:
29.0		 4xiwG-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.23A 4xiwH-4x5sA:
28.9		 4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
None
 1.44A 4xiwH-4x5sA:
28.9		 4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.28A 4xiwH-4x5sA:
28.9		 4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.07A 4xiwH-4x5sA:
28.9		 4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.38A 4xiwH-4x5sA:
28.9		 4xiwH-4x5sA:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 11 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.34A 4ygfA-4x5sA:
30.5		 4ygfA-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 11 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.39A 4ygfB-4x5sA:
30.3		 4ygfB-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  89
HIS A 108
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.42A 4ygfB-4x5sA:
30.3		 4ygfB-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  89
LYS A 112
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
PE8  A 303 (-2.9A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.17A 4ygfB-4x5sA:
30.3		 4ygfB-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 0.76A 4ygfB-4x5sA:
30.3		 4ygfB-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.39A 4ygfB-4x5sA:
30.3		 4ygfB-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 11 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.25A 4ygfC-4x5sA:
22.7		 4ygfC-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  89
HIS A 108
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.49A 4ygfC-4x5sA:
22.7		 4ygfC-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.37A 4ygfC-4x5sA:
22.7		 4ygfC-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 11 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.32A 4ygfD-4x5sA:
4.9		 4ygfD-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.07A 4ygfD-4x5sA:
4.9		 4ygfD-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 GLU A  95
LYS A 112
VAL A 110
LEU A 173
THR A 174
 AZM  A 302 ( 4.5A)
PE8  A 303 (-2.9A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.42A 4ygfE-4x5sA:
30.8		 4ygfE-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 12 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.34A 4ygfE-4x5sA:
30.8		 4ygfE-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  89
HIS A 108
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.44A 4ygfE-4x5sA:
30.8		 4ygfE-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  89
LYS A 112
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
PE8  A 303 (-2.9A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.21A 4ygfE-4x5sA:
30.8		 4ygfE-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 0.76A 4ygfE-4x5sA:
30.8		 4ygfE-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.39A 4ygfE-4x5sA:
30.8		 4ygfE-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.25A 4ygfF-4x5sA:
30.2		 4ygfF-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.35A 4ygfF-4x5sA:
30.2		 4ygfF-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 12 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.30A 4ygfG-4x5sA:
7.6		 4ygfG-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  89
LYS A 112
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
PE8  A 303 (-2.9A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.23A 4ygfG-4x5sA:
7.6		 4ygfG-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.38A 4ygfG-4x5sA:
7.6		 4ygfG-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.11A 4ygfG-4x5sA:
7.6		 4ygfG-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 LYS A 112
VAL A 120
LEU A 173
THR A 174
TRP A 184
 PE8  A 303 (-2.9A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.77A 4ygfG-4x5sA:
7.6		 4ygfG-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.29A 4ygfH-4x5sA:
30.3		 4ygfH-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.34A 4ygfH-4x5sA:
30.3		 4ygfH-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 12 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.41A 4yhaA-4x5sA:
30.4		 4yhaA-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 0.48A 4yhaB-4x5sA:
29.3		 4yhaB-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.16A 4yhaB-4x5sA:
29.3		 4yhaB-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 11 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.34A 4yhaC-4x5sA:
30.8		 4yhaC-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 11 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.43A 4yhaD-4x5sA:
29.3		 4yhaD-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  89
HIS A 108
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.45A 4yhaD-4x5sA:
29.3		 4yhaD-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 12 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
None
 0.41A 4yhaE-4x5sA:
30.6		 4yhaE-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
HIS A 108
LEU A 173
THR A 174
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
None
 1.44A 4yhaE-4x5sA:
30.6		 4yhaE-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  91
VAL A 120
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.14A 4yhaE-4x5sA:
30.6		 4yhaE-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.59A 4yhaF-4x5sA:
27.3		 4yhaF-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 12 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.32A 4yhaG-4x5sA:
30.2		 4yhaG-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 VAL A 110
LYS A 112
VAL A 120
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.8A)
PE8  A 303 (-2.9A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.58A 4yhaG-4x5sA:
30.2		 4yhaG-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 10 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.41A 4yhaH-4x5sA:
30.1		 4yhaH-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.20A 5c8iA-4x5sA:
30.0		 5c8iA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.34A 5c8iA-4x5sA:
30.0		 5c8iA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
PRO A 177
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.07A 5c8iA-4x5sA:
30.0		 5c8iA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 1.26A 5c8iA-4x5sA:
30.0		 5c8iA-4x5sA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.94A 5c8iA-4x5sA:
30.0		 5c8iA-4x5sA:
38.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 PRO A 104
ALA A 193
GLN A 197
ILE A 198
PHE A 201
 None
 1.46A 5ewjA-4x5sA:
undetectable
5ewjB-4x5sA:
undetectable		 5ewjA-4x5sA:
19.22
5ewjB-4x5sA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 PRO A 104
ALA A 193
GLN A 197
ILE A 198
PHE A 201
 None
 1.46A 5ewjC-4x5sA:
undetectable
5ewjD-4x5sA:
undetectable		 5ewjC-4x5sA:
19.22
5ewjD-4x5sA:
20.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.11A 5jn8A-4x5sA:
28.0		 5jn8A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.29A 5jn8A-4x5sA:
28.0		 5jn8A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.45A 5jn8A-4x5sA:
28.0		 5jn8A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.34A 5jn8A-4x5sA:
28.0		 5jn8A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.96A 5jn8A-4x5sA:
28.0		 5jn8A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.09A 5jn8B-4x5sA:
28.3		 5jn8B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.29A 5jn8B-4x5sA:
28.3		 5jn8B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.45A 5jn8B-4x5sA:
28.3		 5jn8B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.96A 5jn8B-4x5sA:
28.3		 5jn8B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.30A 5jn8C-4x5sA:
27.8		 5jn8C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.43A 5jn8C-4x5sA:
27.8		 5jn8C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  91
GLU A  95
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.90A 5jn8D-4x5sA:
27.7		 5jn8D-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
None
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
 1.32A 5jn8D-4x5sA:
27.7		 5jn8D-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.25A 5jn8D-4x5sA:
27.7		 5jn8D-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.13A 5jn9A-4x5sA:
28.0		 5jn9A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.30A 5jn9A-4x5sA:
28.0		 5jn9A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.48A 5jn9A-4x5sA:
28.0		 5jn9A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.35A 5jn9A-4x5sA:
28.0		 5jn9A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.95A 5jn9A-4x5sA:
28.0		 5jn9A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.09A 5jn9B-4x5sA:
28.4		 5jn9B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.30A 5jn9B-4x5sA:
28.4		 5jn9B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.39A 5jn9B-4x5sA:
28.4		 5jn9B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.28A 5jn9C-4x5sA:
27.9		 5jn9C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.47A 5jn9C-4x5sA:
27.9		 5jn9C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.00A 5jn9C-4x5sA:
27.9		 5jn9C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.43A 5jn9C-4x5sA:
27.9		 5jn9C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.28A 5jn9D-4x5sA:
27.6		 5jn9D-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.27A 5jn9D-4x5sA:
27.6		 5jn9D-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.11A 5jn9D-4x5sA:
27.6		 5jn9D-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.31A 5jn9D-4x5sA:
27.6		 5jn9D-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.43A 5jnaA-4x5sA:
27.9		 5jnaA-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 GLN A  67
HIS A  89
HIS A  91
GLU A  95
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.95A 5jnaA-4x5sA:
27.9		 5jnaA-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.05A 5jnaA-4x5sA:
27.9		 5jnaA-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.50A 5jnaA-4x5sA:
27.9		 5jnaA-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.99A 5jnaA-4x5sA:
27.9		 5jnaA-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.42A 5jnaB-4x5sA:
28.3		 5jnaB-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.98A 5jnaB-4x5sA:
28.3		 5jnaB-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.08A 5jnaB-4x5sA:
28.3		 5jnaB-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.31A 5jnaB-4x5sA:
28.3		 5jnaB-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 11 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.44A 5jnaC-4x5sA:
27.7		 5jnaC-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.00A 5jnaC-4x5sA:
27.7		 5jnaC-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.04A 5jnaC-4x5sA:
27.7		 5jnaC-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.47A 5jnaC-4x5sA:
27.7		 5jnaC-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.31A 5jnaC-4x5sA:
27.7		 5jnaC-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.98A 5jnaC-4x5sA:
27.7		 5jnaC-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.41A 5jnaD-4x5sA:
27.6		 5jnaD-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 GLN A  67
HIS A  89
HIS A  91
THR A 174
THR A 175
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.02A 5jnaD-4x5sA:
27.6		 5jnaD-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.03A 5jnaD-4x5sA:
27.6		 5jnaD-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.49A 5jnaD-4x5sA:
27.6		 5jnaD-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.15A 5jnaD-4x5sA:
27.6		 5jnaD-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.30A 5jnaD-4x5sA:
27.6		 5jnaD-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.95A 5jnaD-4x5sA:
27.6		 5jnaD-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
 1.09A 5jncA-4x5sA:
28.0		 5jncA-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.31A 5jncA-4x5sA:
28.0		 5jncA-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.43A 5jncA-4x5sA:
28.0		 5jncA-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 11 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.5A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.97A 5jncA-4x5sA:
28.0		 5jncA-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.26A 5jncB-4x5sA:
28.4		 5jncB-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.33A 5jncB-4x5sA:
28.4		 5jncB-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.42A 5jncB-4x5sA:
28.4		 5jncB-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.27A 5jncC-4x5sA:
27.8		 5jncC-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.25A 5jncD-4x5sA:
27.6		 5jncD-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.12A 5jncD-4x5sA:
27.6		 5jncD-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.46A 5jncD-4x5sA:
27.6		 5jncD-4x5sA:
32.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 12 ARG A 219
VAL A  98
GLY A 122
VAL A  32
ILE A  34
 None
 1.05A 5kqyA-4x5sA:
undetectable		 5kqyA-4x5sA:
20.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.31A 5ku6A-4x5sA:
27.9		 5ku6A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.45A 5ku6A-4x5sA:
27.9		 5ku6A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.34A 5ku6A-4x5sA:
27.9		 5ku6A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.97A 5ku6A-4x5sA:
27.9		 5ku6A-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.15A 5ku6B-4x5sA:
28.3		 5ku6B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.27A 5ku6B-4x5sA:
28.3		 5ku6B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.33A 5ku6B-4x5sA:
28.3		 5ku6B-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.30A 5ku6C-4x5sA:
27.9		 5ku6C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.46A 5ku6C-4x5sA:
27.9		 5ku6C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.14A 5ku6C-4x5sA:
27.9		 5ku6C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.48A 5ku6C-4x5sA:
27.9		 5ku6C-4x5sA:
32.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.28A 5ku6D-4x5sA:
27.7		 5ku6D-4x5sA:
32.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 7 GLN A  87
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 0.31A 5m78A-4x5sA:
30.0		 5m78A-4x5sA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 7 GLN A  87
HIS A  89
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.43A 5m78A-4x5sA:
30.0		 5m78A-4x5sA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 7 HIS A  89
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.15A 5m78A-4x5sA:
30.0		 5m78A-4x5sA:
16.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 6 HIS A  89
HIS A  91
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.20A 5ogjA-4x5sA:
29.9		 5ogjA-4x5sA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 6 HIS A  89
HIS A 108
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.33A 5ogjA-4x5sA:
29.9		 5ogjA-4x5sA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 6 HIS A  89
HIS A  91
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.19A 5ogjB-4x5sA:
29.0		 5ogjB-4x5sA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 6 HIS A  89
HIS A 108
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.34A 5ogjB-4x5sA:
29.0		 5ogjB-4x5sA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 5 HIS A  89
HIS A  91
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.20A 5ohhA-4x5sA:
29.1		 5ohhA-4x5sA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 5 HIS A  89
HIS A 108
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 0.35A 5ohhA-4x5sA:
29.1		 5ohhA-4x5sA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 6 HIS A  89
HIS A  91
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.19A 5ohhB-4x5sA:
29.9		 5ohhB-4x5sA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 6 HIS A  89
HIS A 108
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.31A 5ohhB-4x5sA:
29.9		 5ohhB-4x5sA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
None
 0.40A 5tt3A-4x5sA:
30.3		 5tt3A-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 10 HIS A  89
HIS A 108
THR A 174
PRO A 176
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.3A)
None
None
 1.33A 5tt3A-4x5sA:
30.3		 5tt3A-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.37A 5tt3A-4x5sA:
30.3		 5tt3A-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.34A 5tt3B-4x5sA:
28.1		 5tt3B-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.24A 5tt3B-4x5sA:
28.1		 5tt3B-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		9 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
None
 0.34A 5tt3C-4x5sA:
30.6		 5tt3C-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.38A 5tt3C-4x5sA:
30.6		 5tt3C-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.39A 5tt3E-4x5sA:
30.7		 5tt3E-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  91
HIS A 108
VAL A 120
LEU A 173
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
None
 1.48A 5tt3E-4x5sA:
30.7		 5tt3E-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.49A 5tt3E-4x5sA:
30.7		 5tt3E-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 8 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.40A 5tt3F-4x5sA:
29.5		 5tt3F-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.32A 5tt3G-4x5sA:
29.4		 5tt3G-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		5 / 9 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
 1.32A 5tt3G-4x5sA:
29.4		 5tt3G-4x5sA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 8 HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 0.43A 5tt3H-4x5sA:
29.8		 5tt3H-4x5sA:
37.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  89
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.23A 6bbsA-4x5sA:
23.8		 6bbsA-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 12 TRP A   3
ASN A  62
HIS A  64
GLN A  87
HIS A  89
HIS A  91
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
None
None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.56A 6bbsA-4x5sA:
23.8		 6bbsA-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 TRP A   3
HIS A  64
HIS A  89
THR A 174
THR A 175
TRP A 184
 None
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 1.45A 6bbsA-4x5sA:
23.8		 6bbsA-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		11 / 12 TRP A   3
ASN A  62
GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 None
None
AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.50A 6bc9A-4x5sA:
30.0		 6bc9A-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 TRP A   3
GLN A  67
HIS A  91
LEU A 173
THR A 174
THR A 175
 None
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.12A 6bc9A-4x5sA:
30.0		 6bc9A-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 TRP A   3
HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
PRO A 177
 None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.26A 6bc9A-4x5sA:
30.0		 6bc9A-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		7 / 12 TRP A   3
HIS A  89
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 None
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 1.34A 6bc9A-4x5sA:
30.0		 6bc9A-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		4 / 5 HIS A  64
GLU A  95
HIS A 108
VAL A 120
 None
AZM  A 302 ( 4.5A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
 0.25A 6bc9A-4x5sA:
30.0		 6bc9A-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
 1.28A 6bccA-4x5sA:
29.9		 6bccA-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 AZM  A 302 (-4.3A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 0.33A 6bccA-4x5sA:
29.9		 6bccA-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
PRO A 177
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
None
 1.10A 6bccA-4x5sA:
29.9		 6bccA-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  89
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.1A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
None
 1.30A 6bccA-4x5sA:
29.9		 6bccA-4x5sA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4x5s CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(Sulfurihydrogeni
bium
azorense) 		6 / 12 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.8A)
AZM  A 302 (-3.7A)
AZM  A 302 (-3.3A)
AZM  A 302 (-3.3A)
None
 0.94A 6bccA-4x5sA:
29.9		 6bccA-4x5sA:
19.90