SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 4x82 ZINC TRANSPORTER
ZIP4
(Pteropus
alecto) 		4 / 4 LEU B 118
SER B  97
LEU B 132
LEU B 176
 None
 1.18A 1yajA-4x82B:
2.3		 1yajA-4x82B:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 4x82 ZINC TRANSPORTER
ZIP4
(Pteropus
alecto) 		4 / 4 LEU B 179
SER B  97
LEU B 122
LEU B 132
 None
 1.12A 1yajA-4x82B:
2.3		 1yajA-4x82B:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4x82 ZINC TRANSPORTER
ZIP4
(Pteropus
alecto) 		5 / 10 LEU B 176
ALA B  93
ILE B 139
LEU B  96
LEU B 136
 None
 1.01A 1yi4A-4x82B:
undetectable		 1yi4A-4x82B:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4x82 ZINC TRANSPORTER
ZIP4
(Pteropus
alecto) 		4 / 5 GLN B 140
THR B 143
LEU B 176
LEU B 179
 None
 1.01A 4lvcB-4x82B:
undetectable		 4lvcB-4x82B:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 4x82 ZINC TRANSPORTER
ZIP4
(Pteropus
alecto) 		5 / 10 ALA B  92
LEU B  46
LEU B 180
LEU B 176
ALA B 177
 None
 1.08A 4zbrA-4x82B:
undetectable		 4zbrA-4x82B:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 4x82 ZINC TRANSPORTER
ZIP4
(Pteropus
alecto) 		5 / 11 ALA B 288
ALA B 290
VAL B 199
LEU B 218
VAL B 202
 None
 1.08A 5eb5A-4x82B:
undetectable		 5eb5A-4x82B:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 4x82 ZINC TRANSPORTER
ZIP4
(Pteropus
alecto) 		5 / 10 ALA B 288
ALA B 290
VAL B 199
LEU B 218
VAL B 202
 None
 1.13A 5eb5B-4x82B:
undetectable		 5eb5B-4x82B:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4x82 ZINC TRANSPORTER
ZIP4
(Pteropus
alecto) 		4 / 4 GLN B 140
THR B 143
LEU B 176
LEU B 179
 None
 1.05A 5m5kB-4x82B:
undetectable		 5m5kB-4x82B:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4x82 ZINC TRANSPORTER
ZIP4
(Pteropus
alecto) 		5 / 10 ALA B  92
LEU B 118
LEU B 119
LEU B 179
LEU B 135
 None
 0.83A 6f5uA-4x82B:
undetectable
6f5uB-4x82B:
undetectable		 6f5uA-4x82B:
14.63
6f5uB-4x82B:
17.68