SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4x8f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 LEU A 135
ALA A 149
GLY A 145
LEU A 162
GLN A 138
 None
 1.35A 1brpA-4x8fA:
undetectable		 1brpA-4x8fA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.52A 1bx4A-4x8fA:
30.0		 1bx4A-4x8fA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 THR A 220
GLY A 222
ALA A 250
GLY A 251
HIS A 276
ALA A 279
 None
 0.61A 1bx4A-4x8fA:
30.0		 1bx4A-4x8fA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		3 / 3 ARG A  71
THR A  92
VAL A  61
 None
 0.89A 1hxbA-4x8fA:
undetectable		 1hxbA-4x8fA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.55A 1liiA-4x8fA:
26.6		 1liiA-4x8fA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.62A 1likA-4x8fA:
29.3		 1likA-4x8fA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 10 THR A 220
GLY A 222
VAL A 226
ALA A 250
ALA A 279
 None
 0.67A 1likA-4x8fA:
29.3		 1likA-4x8fA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 11 GLY A  83
PHE A  74
GLY A  56
GLY A   8
GLY A  41
 None
 0.96A 1mxgA-4x8fA:
undetectable		 1mxgA-4x8fA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ILE A 218
ALA A 279
GLY A 225
GLY A 239
LEU A 221
 None
 1.06A 1rjdB-4x8fA:
2.7		 1rjdB-4x8fA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ILE A 218
ALA A 279
GLY A 225
GLY A 239
LEU A 221
 None
 1.07A 1rjdC-4x8fA:
2.6		 1rjdC-4x8fA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 11 VAL A 178
ILE A 214
LEU A 175
LEU A 139
LEU A 170
 None
 1.05A 2a15A-4x8fA:
undetectable		 2a15A-4x8fA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		4 / 5 LEU A 135
LEU A 136
LEU A 180
LEU A 162
 None
 0.91A 2ab2B-4x8fA:
undetectable		 2ab2B-4x8fA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ALA A  95
ASP A 252
 None
 0.63A 2c49A-4x8fA:
31.6		 2c49A-4x8fA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		4 / 7 ASP A  13
GLY A  38
GLY A  39
ASN A  43
 None
 0.31A 2c49B-4x8fA:
33.5		 2c49B-4x8fA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 GLY A  39
ALA A 249
THR A 248
THR A 253
ALA A  47
 None
 1.07A 2gluA-4x8fA:
3.8		 2gluA-4x8fA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 GLY A  39
ALA A 249
THR A 248
THR A 253
ALA A  47
 None
 1.03A 2gluB-4x8fA:
3.3		 2gluB-4x8fA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.56A 2pkkA-4x8fA:
29.2		 2pkkA-4x8fA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.58A 2pkmA-4x8fA:
29.1		 2pkmA-4x8fA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		3 / 3 ARG A  71
THR A  92
VAL A  61
 None
 1.00A 2qakA-4x8fA:
undetectable		 2qakA-4x8fA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 11 ALA A 188
THR A 192
ILE A 219
ALA A 202
ALA A 206
 None
 0.98A 2qhfA-4x8fA:
undetectable		 2qhfA-4x8fA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 9 ALA A 250
ALA A 244
GLY A 239
SER A 282
ALA A 280
 None
 1.25A 2vh3A-4x8fA:
undetectable		 2vh3A-4x8fA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		4 / 7 VAL A 259
VAL A  55
ASN A 255
GLY A 256
 None
 0.95A 3kmoB-4x8fA:
undetectable		 3kmoB-4x8fA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.52A 3uboA-4x8fA:
29.6		 3uboA-4x8fA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.73A 3uboB-4x8fA:
30.5		 3uboB-4x8fA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.63A 3vaqA-4x8fA:
30.0		 3vaqA-4x8fA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.57A 3vasA-4x8fA:
29.9		 3vasA-4x8fA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.52A 3vasB-4x8fA:
21.7		 3vasB-4x8fA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.65A 4dc3B-4x8fA:
29.9		 4dc3B-4x8fA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 GLY A  56
ALA A  59
ASP A 125
ALA A 128
VAL A   5
 None
 1.37A 4df3A-4x8fA:
4.3		 4df3A-4x8fA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.73A 4e3aA-4x8fA:
30.2		 4e3aA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.74A 4e3aB-4x8fA:
30.1		 4e3aB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4jksA-4x8fA:
30.3		 4jksA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4jksB-4x8fA:
30.3		 4jksB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.68A 4jkuA-4x8fA:
28.6		 4jkuA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.68A 4jkuB-4x8fA:
30.3		 4jkuB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4k8cA-4x8fA:
28.4		 4k8cA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4k8cB-4x8fA:
30.2		 4k8cB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4k8kA-4x8fA:
30.2		 4k8kA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4k8kB-4x8fA:
30.2		 4k8kB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4k8pA-4x8fA:
30.3		 4k8pA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.72A 4k8pB-4x8fA:
30.2		 4k8pB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4k8tA-4x8fA:
30.2		 4k8tA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.72A 4k8tB-4x8fA:
30.2		 4k8tB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.71A 4k93A-4x8fA:
30.3		 4k93A-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4k93B-4x8fA:
30.3		 4k93B-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.71A 4k9cA-4x8fA:
30.3		 4k9cA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4k9cB-4x8fA:
30.3		 4k9cB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4k9iA-4x8fA:
30.2		 4k9iA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4k9iB-4x8fA:
30.2		 4k9iB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4kadA-4x8fA:
30.3		 4kadA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4kadB-4x8fA:
28.4		 4kadB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4kahA-4x8fA:
28.5		 4kahA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4kahB-4x8fA:
30.3		 4kahB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4kalA-4x8fA:
30.3		 4kalA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4kalB-4x8fA:
30.2		 4kalB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4kanA-4x8fA:
28.5		 4kanA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4kanB-4x8fA:
30.3		 4kanB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.73A 4kbeA-4x8fA:
28.5		 4kbeA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4kbeB-4x8fA:
28.5		 4kbeB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		4 / 7 SER A 282
GLY A  38
ASP A  13
GLU A 140
 None
 0.92A 4koeA-4x8fA:
undetectable
4koeB-4x8fA:
undetectable
4koeD-4x8fA:
2.2		 4koeA-4x8fA:
20.95
4koeB-4x8fA:
20.95
4koeD-4x8fA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4lbgA-4x8fA:
30.2		 4lbgA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4lbgB-4x8fA:
30.3		 4lbgB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.71A 4lbxA-4x8fA:
30.3		 4lbxA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.71A 4lbxB-4x8fA:
30.2		 4lbxB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.70A 4lc4A-4x8fA:
30.2		 4lc4A-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.72A 4lc4B-4x8fA:
30.2		 4lc4B-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.71A 4lcaA-4x8fA:
30.3		 4lcaA-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
THR A 248
ASP A 252
 None
 0.69A 4lcaB-4x8fA:
30.2		 4lcaB-4x8fA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.54A 4n09B-4x8fA:
29.7		 4n09B-4x8fA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.56A 4n09C-4x8fA:
29.6		 4n09C-4x8fA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.55A 4n09D-4x8fA:
29.7		 4n09D-4x8fA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 9 ALA A 249
THR A 248
ALA A 250
GLY A  38
GLY A  39
 None
 1.11A 4qwuY-4x8fA:
undetectable
4qwuZ-4x8fA:
undetectable		 4qwuY-4x8fA:
19.81
4qwuZ-4x8fA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 GLY A  78
ALA A  49
PHE A  57
ALA A  42
VAL A  10
 None
 1.09A 4ryaA-4x8fA:
undetectable		 4ryaA-4x8fA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		5 / 12 ASP A  13
GLY A  38
GLY A  39
ASN A  43
ASP A 252
 None
 0.56A 4ubeA-4x8fA:
29.2		 4ubeA-4x8fA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		4 / 7 GLY A  38
ASP A  13
GLU A 140
SER A 282
 None
 0.88A 4z53A-4x8fA:
undetectable
4z53B-4x8fA:
undetectable		 4z53A-4x8fA:
19.16
4z53B-4x8fA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		4 / 4 LEU A 209
ILE A 214
PRO A 164
LEU A 170
 None
 1.13A 5eb3A-4x8fA:
2.5		 5eb3A-4x8fA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 THR A 220
GLY A 222
ALA A 250
GLY A 251
HIS A 276
ALA A 279
 None
 0.64A 5kb6A-4x8fA:
29.2		 5kb6A-4x8fA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 THR A 220
GLY A 222
ALA A 250
GLY A 251
HIS A 276
ALA A 279
 None
 0.63A 5kb6B-4x8fA:
29.2		 5kb6B-4x8fA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4x8f RIBOKINASE
(Vibrio
cholerae) 		6 / 12 ILE A 146
ALA A 150
ALA A 149
GLN A 151
LEU A 174
LEU A 117
 None
 1.39A 6a5yD-4x8fA:
undetectable		 6a5yD-4x8fA:
15.92