SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xa7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4xa7 NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT C
(Vibrio
harveyi) 		5 / 12 GLN A 192
THR A 238
LEU A 225
GLY A 224
PHE A 193
 None
 1.36A 3g1uB-4xa7A:
undetectable		 3g1uB-4xa7A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4xa7 NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT C
(Vibrio
harveyi) 		5 / 12 GLN A 192
THR A 238
LEU A 225
GLY A 224
PHE A 193
 None
 1.37A 5m66C-4xa7A:
undetectable		 5m66C-4xa7A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 4xa7 NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT C
(Vibrio
harveyi) 		5 / 12 PHE A  66
ILE A  50
SER A 167
VAL A 131
ILE A  55
 None
 1.27A 5mlmA-4xa7A:
undetectable		 5mlmA-4xa7A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 4xa7 NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT C
(Vibrio
harveyi) 		4 / 8 ILE A 141
TYR A 171
THR A 170
ILE A 169
 None
 0.72A 5mzrE-4xa7A:
undetectable		 5mzrE-4xa7A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 4xa7 NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT C
(Vibrio
harveyi) 		5 / 12 LEU A 180
GLY A 181
GLY A 182
VAL A 184
LEU A 230
 FMN  A 301 (-4.0A)
FMN  A 301 (-3.4A)
None
None
FMN  A 301 (-3.9A)
 1.16A 5uc1B-4xa7A:
undetectable		 5uc1B-4xa7A:
15.38