SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		3 / 3 TRP A 304
VAL A  11
TRP A   6
 None
 1.07A 1c4dA-4xb3A:
undetectable
1c4dB-4xb3A:
undetectable		 1c4dA-4xb3A:
3.72
1c4dB-4xb3A:
3.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		6 / 12 TYR A  63
ARG A 192
ASP A 194
HIS A 312
ASP A 313
ARG A 402
 None
 0.66A 1dedB-4xb3A:
30.2		 1dedB-4xb3A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ALA A 224
ALA A 223
GLN A 228
PHE A 226
HIS A 215
 None
 1.06A 1fbyA-4xb3A:
undetectable		 1fbyA-4xb3A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ALA A 224
ALA A 223
GLN A 228
PHE A 226
HIS A 215
 None
 1.05A 1fbyB-4xb3A:
undetectable		 1fbyB-4xb3A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ILE A 196
GLY A 235
SER A 257
MET A 221
LEU A 232
 None
 1.46A 1fm6X-4xb3A:
undetectable		 1fm6X-4xb3A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 LEU A  40
LEU A  43
GLY A  44
VAL A  11
ALA A  88
 None
 1.11A 1gs4A-4xb3A:
undetectable		 1gs4A-4xb3A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 9 VAL A 490
ALA A 519
THR A 514
THR A 509
SER A 517
 None
 1.36A 1gtnL-4xb3A:
undetectable
1gtnM-4xb3A:
undetectable		 1gtnL-4xb3A:
8.99
1gtnM-4xb3A:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		7 / 12 TYR A  63
HIS A 103
PHE A 158
ARG A 192
ASP A 194
HIS A 312
ASP A 313
 None
 0.96A 1mxdA-4xb3A:
24.5		 1mxdA-4xb3A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		3 / 3 ASN A 492
ALA A 334
ASN A 513
 None
 0.82A 1n4fA-4xb3A:
undetectable		 1n4fA-4xb3A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		3 / 3 ARG A 173
ASP A 178
ASP A 185
 None
 0.85A 2ejtA-4xb3A:
undetectable		 2ejtA-4xb3A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 10 ASN A 311
GLU A 353
LEU A  43
LEU A  40
TYR A  39
 None
 1.24A 2ha6A-4xb3A:
undetectable		 2ha6A-4xb3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 6 ASP A 313
ARG A 398
ASP A 399
ASP A  60
 None
 1.23A 2j2pE-4xb3A:
undetectable
2j2pF-4xb3A:
undetectable		 2j2pE-4xb3A:
16.47
2j2pF-4xb3A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 6 PRO A 212
ILE A 202
GLY A 200
TYR A 217
 None
 0.83A 2jkjA-4xb3A:
undetectable		 2jkjA-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 6 PRO A 212
ILE A 202
GLY A 200
TYR A 217
 None
 0.83A 2jkjB-4xb3A:
undetectable		 2jkjB-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 6 PRO A 212
ILE A 202
GLY A 200
TYR A 217
 None
 0.83A 2jkjC-4xb3A:
undetectable		 2jkjC-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 5 PRO A 212
ILE A 202
GLY A 200
TYR A 217
 None
 0.83A 2jkjD-4xb3A:
undetectable		 2jkjD-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 5 PRO A 212
ILE A 207
GLY A 200
TYR A 217
 None
 1.15A 2jkjD-4xb3A:
undetectable		 2jkjD-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 5 PRO A 212
ILE A 202
GLY A 200
TYR A 217
 None
 0.83A 2jkjF-4xb3A:
undetectable		 2jkjF-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 5 PRO A 212
ILE A 207
GLY A 200
TYR A 217
 None
 1.15A 2jkjF-4xb3A:
undetectable		 2jkjF-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 6 PRO A 212
ILE A 202
GLY A 200
TYR A 217
 None
 0.85A 2jklB-4xb3A:
undetectable		 2jklB-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		3 / 3 LEU A 256
TYR A 248
GLN A 247
 None
 0.66A 2wekA-4xb3A:
undetectable		 2wekA-4xb3A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ARG A 192
ASP A 194
HIS A 312
ASP A 313
ASP A  60
 None
 0.74A 3aicA-4xb3A:
3.0		 3aicA-4xb3A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ARG A 192
ASP A 194
HIS A 312
ASP A 313
ASP A  60
 None
 0.73A 3aicB-4xb3A:
3.0		 3aicB-4xb3A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		6 / 12 ARG A 192
ASP A 194
HIS A 312
ASP A 313
ASP A  60
TYR A  63
 None
 0.71A 3aicC-4xb3A:
2.2		 3aicC-4xb3A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ARG A 192
ASP A 194
HIS A 312
ASP A 313
ASP A  60
 None
 0.80A 3aicD-4xb3A:
4.5		 3aicD-4xb3A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ARG A 192
ASP A 194
HIS A 312
ASP A 313
ASP A  60
 None
 0.78A 3aicE-4xb3A:
6.2		 3aicE-4xb3A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ARG A 192
ASP A 194
HIS A 312
ASP A 313
ASP A  60
 None
 0.75A 3aicF-4xb3A:
4.5		 3aicF-4xb3A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ARG A 192
ASP A 194
HIS A 312
ASP A 313
ASP A  60
 None
 0.74A 3aicG-4xb3A:
4.2		 3aicG-4xb3A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ARG A 192
ASP A 194
HIS A 312
ASP A 313
ASP A  60
 None
 0.79A 3aicH-4xb3A:
3.6		 3aicH-4xb3A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		3 / 3 PRO A 163
PHE A 139
LYS A 160
 None
 1.18A 3bjwG-4xb3A:
undetectable		 3bjwG-4xb3A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 11 MET A  20
ILE A  48
LEU A  40
PHE A  19
THR A  22
 None
 1.17A 3fl9C-4xb3A:
undetectable		 3fl9C-4xb3A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 9 MET A  20
ILE A  48
LEU A  40
PHE A  19
THR A  22
 None
 1.22A 3fl9H-4xb3A:
undetectable		 3fl9H-4xb3A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG8_A_TOYA305_1
(APH(2'')-ID)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ASN A  61
SER A 372
ASP A 313
TYR A  15
TRP A 422
 None
 1.29A 3sg8A-4xb3A:
2.4		 3sg8A-4xb3A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_B_SAMB401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 11 TYR A  15
ASP A 399
ASP A 368
GLU A 366
PRO A 404
 None
 1.44A 4dmgB-4xb3A:
undetectable		 4dmgB-4xb3A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 8 ILE A 265
GLY A 397
ASN A 358
GLU A 371
 None
 0.97A 4fgjA-4xb3A:
undetectable
4fgjB-4xb3A:
undetectable		 4fgjA-4xb3A:
18.03
4fgjB-4xb3A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		3 / 3 ASP A 313
TRP A 422
SER A  51
 None
 1.08A 4lrhF-4xb3A:
undetectable		 4lrhF-4xb3A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		3 / 3 MET A 356
MET A 395
TYR A 349
 None
 1.28A 4p6xI-4xb3A:
undetectable		 4p6xI-4xb3A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 5 ARG A 316
ARG A 398
GLY A 397
GLU A 371
 None
 1.28A 4z3oA-4xb3A:
undetectable
4z3oB-4xb3A:
undetectable		 4z3oA-4xb3A:
21.41
4z3oB-4xb3A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ARG A 192
ASP A 194
HIS A 264
HIS A 312
ASP A 313
 None
 0.81A 5csyB-4xb3A:
20.0		 5csyB-4xb3A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 VAL A 475
ALA A 477
THR A 514
PHE A 531
ASN A 492
 None
 1.41A 5hgcA-4xb3A:
undetectable		 5hgcA-4xb3A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 7 ILE A 396
GLY A 397
PHE A 158
ASP A 313
 None
 0.84A 5hieA-4xb3A:
undetectable		 5hieA-4xb3A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 ILE A 244
GLY A 239
TYR A 248
HIS A 215
ILE A 207
 None
 1.34A 5igwA-4xb3A:
undetectable		 5igwA-4xb3A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 7 LEU A 298
ILE A 196
THR A 237
MET A 193
 None
 0.96A 5ljcA-4xb3A:
undetectable		 5ljcA-4xb3A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 6 ASN A  61
PRO A  16
ASP A  60
TYR A  63
 None
 1.20A 5umd2-4xb3A:
undetectable
5umdF-4xb3A:
undetectable		 5umd2-4xb3A:
9.75
5umdF-4xb3A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		5 / 12 TYR A  63
HIS A 103
ASP A 194
HIS A 312
ASP A 313
 None
 0.48A 6ag0A-4xb3A:
21.2		 6ag0A-4xb3A:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		3 / 3 LYS A 270
VAL A 279
ASP A 277
 None
 0.65A 6fgdA-4xb3A:
undetectable		 6fgdA-4xb3A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E
(Streptococcus
mutans) 		4 / 8 GLN A 236
ILE A  96
ARG A 192
ASP A 313
 None
 1.05A 6hu9a-4xb3A:
undetectable
6hu9e-4xb3A:
undetectable		 6hu9a-4xb3A:
21.83
6hu9e-4xb3A:
12.83