SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xbr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICR_A_NIOA604_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 5	SER A 443 THR A 404 GLU A 507 GLY A 511	None	0.89A	1icrA-4xbrA: undetectable 1icrB-4xbrA: undetectable	1icrA-4xbrA: 21.35 1icrB-4xbrA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICR_B_NIOB602_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 5	GLU A 507 GLY A 511 SER A 443 THR A 404	None	0.89A	1icrA-4xbrA: undetectable 1icrB-4xbrA: undetectable	1icrA-4xbrA: 21.35 1icrB-4xbrA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_A_NIOA221_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 6	SER A 443 THR A 404 GLU A 507 GLY A 511	None	0.93A	1icuA-4xbrA: undetectable 1icuB-4xbrA: undetectable	1icuA-4xbrA: 21.35 1icuB-4xbrA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_B_NIOB219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 6	GLU A 507 GLY A 511 SER A 443 THR A 404	None	0.92A	1icuA-4xbrA: undetectable 1icuB-4xbrA: undetectable	1icuA-4xbrA: 21.35 1icuB-4xbrA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_C_NIOC225_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 6	SER A 443 THR A 404 GLU A 507 GLY A 511	None	0.93A	1icuC-4xbrA: undetectable 1icuD-4xbrA: undetectable	1icuC-4xbrA: 21.35 1icuD-4xbrA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICV_C_NIOC708_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 5	SER A 443 THR A 404 GLU A 507 GLY A 511	None	0.91A	1icvC-4xbrA: undetectable 1icvD-4xbrA: undetectable	1icvC-4xbrA: 21.35 1icvD-4xbrA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICV_D_NIOD706_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 5	GLU A 507 GLY A 511 SER A 443 THR A 404	None	0.95A	1icvC-4xbrA: undetectable 1icvD-4xbrA: undetectable	1icvC-4xbrA: 21.35 1icvD-4xbrA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_A_BEZA524_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 6	SER A 443 THR A 404 GLU A 507 GLY A 511	None	0.91A	1kqbA-4xbrA: undetectable 1kqbB-4xbrA: undetectable	1kqbA-4xbrA: 20.54 1kqbB-4xbrA: 20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_B_BEZB525_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 5	GLU A 507 GLY A 511 SER A 443 THR A 404	None	0.93A	1kqbA-4xbrA: undetectable 1kqbB-4xbrA: undetectable	1kqbA-4xbrA: 20.54 1kqbB-4xbrA: 20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_C_BEZC522_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 6	SER A 443 THR A 404 GLU A 507 GLY A 511	None	0.88A	1kqbC-4xbrA: undetectable 1kqbD-4xbrA: undetectable	1kqbC-4xbrA: 20.54 1kqbD-4xbrA: 20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_D_BEZD523_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 6	GLU A 507 GLY A 511 SER A 443 THR A 404	None	0.89A	1kqbC-4xbrA: undetectable 1kqbD-4xbrA: undetectable	1kqbC-4xbrA: 20.54 1kqbD-4xbrA: 20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MOG_A_RBFA200_1 (DODECIN)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	3 / 3	PHE A 324 TRP A 392 GLU A 390	None	0.85A	1mogA-4xbrA: undetectable	1mogA-4xbrA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX1_B_THAB2_1 (LIVER CARBOXYLESTERASE I)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 11	PHE A 548 VAL A 407 LEU A 403 LEU A 552 LEU A 501	None	1.34A	1mx1B-4xbrA: undetectable	1mx1B-4xbrA: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AA6_B_STRB402_1 (MINERALOCORTICOID RECEPTOR)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	ASN A 377 LEU A 456 ALA A 427 LEU A 501 LEU A 572	None	1.14A	2aa6B-4xbrA: undetectable	2aa6B-4xbrA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CC8_A_RBFA1067_1 (VNG1446H)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	3 / 3	PHE A 324 VAL A 349 TRP A 392	None	0.85A	2cc8A-4xbrA: undetectable	2cc8A-4xbrA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CCB_A_RBFA1067_1 (VNG1446H)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	3 / 3	PHE A 324 VAL A 349 TRP A 392	None	0.85A	2ccbA-4xbrA: undetectable	2ccbA-4xbrA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EVA_A_ADNA498_1 (TAK1 KINASE - TAB1 CHIMERA FUSION PROTEIN)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 11	GLY A 328 GLY A 330 VAL A 335 ALA A 348 MET A 395 LEU A 447	ATP A 601 ( 4.1A) ATP A 601 (-3.4A) ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-4.3A) None	0.56A	2evaA-4xbrA: 17.7	2evaA-4xbrA: 24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GQG_A_1N1A501_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	ALA A 348 LYS A 350 MET A 370 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None None ATP A 601 (-4.6A) None None	0.76A	2gqgA-4xbrA: 21.2	2gqgA-4xbrA: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_A_STIA600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	VAL A 335 ALA A 348 GLU A 366 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 ( 3.7A) ATP A 601 (-4.6A) None None	0.77A	2hyyA-4xbrA: 16.7	2hyyA-4xbrA: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_B_STIB600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	VAL A 335 ALA A 348 GLU A 366 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 ( 3.7A) ATP A 601 (-4.6A) None None	0.69A	2hyyB-4xbrA: 16.7	2hyyB-4xbrA: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_C_STIC600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	VAL A 335 ALA A 348 GLU A 366 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 ( 3.7A) None ATP A 601 (-4.6A) None None	0.81A	2hyyC-4xbrA: 16.6	2hyyC-4xbrA: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ITY_A_IREA2020_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	8 / 12	GLY A 328 VAL A 335 ALA A 348 LYS A 350 MET A 370 GLY A 401 LEU A 447 ASP A 458	ATP A 601 ( 4.1A) ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None None None ATP A 601 ( 2.5A)	0.56A	2ityA-4xbrA: 19.9	2ityA-4xbrA: 26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ITZ_A_IREA2021_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	VAL A 335 ALA A 348 LYS A 350 MET A 370 GLY A 401 LEU A 447 ASP A 458	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None None None ATP A 601 ( 2.5A)	0.66A	2itzA-4xbrA: 20.0	2itzA-4xbrA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_D_SNLD4001_1 (MINERALOCORTICOID RECEPTOR)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	ASN A 377 LEU A 456 ALA A 427 LEU A 501 LEU A 572	None	1.14A	2oaxD-4xbrA: undetectable	2oaxD-4xbrA: 18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_E_SNLE5001_1 (MINERALOCORTICOID RECEPTOR)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	ASN A 377 LEU A 456 ALA A 427 LEU A 501 LEU A 572	None	1.17A	2oaxE-4xbrA: undetectable	2oaxE-4xbrA: 18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VX9_A_RBFA1064_1 (DODECIN)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	3 / 3	PHE A 324 VAL A 349 TRP A 392	None	0.83A	2vx9A-4xbrA: undetectable	2vx9A-4xbrA: 12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y00_B_Y00B601_1 (BETA-1 ADRENERGIC RECEPTOR)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	LEU A 456 VAL A 424 ASP A 444 SER A 180 PHE A 516	None	1.29A	2y00B-4xbrA: undetectable	2y00B-4xbrA: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y01_B_Y00B601_1 (BETA-1 ADRENERGIC RECEPTOR)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	LEU A 456 VAL A 424 ASP A 444 SER A 180 PHE A 516	None	1.25A	2y01B-4xbrA: undetectable	2y01B-4xbrA: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y6O_A_1N1A1892_1 (EPHRIN TYPE-A RECEPTOR 4)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	ILE A 327 ALA A 348 LYS A 350 MET A 370 GLY A 401 LEU A 447 SER A 457	None ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None None None ATP A 601 ( 4.6A)	0.81A	2y6oA-4xbrA: 17.3	2y6oA-4xbrA: 24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	GLY A 328 ALA A 348 LYS A 350 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP A 601 ( 4.1A) ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None ATP A 601 (-4.6A) None None	0.54A	3c7qA-4xbrA: 17.5	3c7qA-4xbrA: 25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K2H_A_LYAA514_1 (DIHYDROFOLATE REDUCTASE/THYMIDYLAT E SYNTHASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	ALA A 463 ILE A 441 SER A 445 LEU A 456 LEU A 431	SEP A 474 ( 4.1A) None MG A 603 ( 4.0A) None None	1.06A	3k2hA-4xbrA: undetectable	3k2hA-4xbrA: 21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K5V_A_STIA2_1 (TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	VAL A 335 ALA A 348 GLU A 366 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 ( 3.7A) ATP A 601 (-4.6A) None None	0.68A	3k5vA-4xbrA: 16.0	3k5vA-4xbrA: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K5V_B_STIB2_1 (TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	VAL A 335 ALA A 348 GLU A 366 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 ( 3.7A) ATP A 601 (-4.6A) None None	0.68A	3k5vB-4xbrA: 16.0	3k5vB-4xbrA: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MIY_A_B49A1_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	8 / 11	ILE A 327 ALA A 348 LYS A 350 VAL A 379 PHE A 397 LEU A 447 SER A 457 ASP A 458	None ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None ATP A 601 (-4.6A) None ATP A 601 ( 4.6A) ATP A 601 ( 2.5A)	0.84A	3miyA-4xbrA: 19.4	3miyA-4xbrA: 24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MIY_A_B49A1_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 11	LYS A 350 VAL A 379 PHE A 397 GLY A 401 LEU A 447 SER A 457 ASP A 458	ATP A 601 (-2.8A) None ATP A 601 (-4.6A) None None ATP A 601 ( 4.6A) ATP A 601 ( 2.5A)	0.85A	3miyA-4xbrA: 19.4	3miyA-4xbrA: 24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MIY_B_B49B2_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 9	ILE A 327 ALA A 348 LYS A 350 PHE A 397 LEU A 447 SER A 457	None ATP A 601 ( 3.7A) ATP A 601 (-2.8A) ATP A 601 (-4.6A) None ATP A 601 ( 4.6A)	0.73A	3miyB-4xbrA: 22.7	3miyB-4xbrA: 24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MS9_B_STIB1_1 (TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	VAL A 335 ALA A 348 GLU A 366 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 ( 3.7A) ATP A 601 (-4.6A) None None	0.67A	3ms9B-4xbrA: 16.5	3ms9B-4xbrA: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MSS_B_STIB1_1 (TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	VAL A 335 ALA A 348 GLU A 366 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 ( 3.7A) ATP A 601 (-4.6A) None None	0.65A	3mssB-4xbrA: 16.7	3mssB-4xbrA: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PYY_A_STIA3_1 (V-ABL ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 ISOFORM B VARIANT)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	VAL A 335 ALA A 348 GLU A 366 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 ( 3.7A) ATP A 601 (-4.6A) None None	0.78A	3pyyA-4xbrA: 16.7	3pyyA-4xbrA: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RF4_A_FUNA201_1 (MACROPHAGE MIGRATION INHIBITORY FACTOR)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 11	MET A 508 SER A 443 ILE A 446 VAL A 420 VAL A 454	None	1.31A	3rf4A-4xbrA: undetectable 3rf4C-4xbrA: undetectable	3rf4A-4xbrA: 15.84 3rf4C-4xbrA: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RF4_B_FUNB202_1 (MACROPHAGE MIGRATION INHIBITORY FACTOR)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 11	MET A 508 SER A 443 ILE A 446 VAL A 420 VAL A 454	None	1.33A	3rf4A-4xbrA: undetectable 3rf4B-4xbrA: undetectable	3rf4A-4xbrA: 15.84 3rf4B-4xbrA: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SXR_B_1N1B2_1 (CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	VAL A 335 ALA A 348 MET A 370 VAL A 379 GLY A 401 LEU A 447 SER A 457	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) None None None None ATP A 601 ( 4.6A)	0.83A	3sxrB-4xbrA: 19.5	3sxrB-4xbrA: 24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UE4_A_DB8A601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	ALA A 348 LYS A 350 GLU A 366 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP A 601 ( 3.7A) ATP A 601 (-2.8A) ATP A 601 ( 3.7A) None ATP A 601 (-4.6A) None None	0.76A	3ue4A-4xbrA: 20.5	3ue4A-4xbrA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UE4_B_DB8B601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	8 / 12	VAL A 335 ALA A 348 GLU A 366 MET A 370 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 ( 3.7A) None None ATP A 601 (-4.6A) None None	0.87A	3ue4B-4xbrA: 18.5	3ue4B-4xbrA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WZD_A_LEVA1201_2 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 5	ILE A 369 VAL A 379 LEU A 447 ASP A 458	None None None ATP A 601 ( 2.5A)	0.74A	3wzdA-4xbrA: 17.9	3wzdA-4xbrA: 24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WZD_A_LEVA1201_2 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 5	LYS A 350 ILE A 369 VAL A 379 ASP A 458	ATP A 601 (-2.8A) None None ATP A 601 ( 2.5A)	1.04A	3wzdA-4xbrA: 17.9	3wzdA-4xbrA: 24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOS_A_0LIA1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	ALA A 348 LYS A 350 GLU A 366 LEU A 431 HIS A 438 ARG A 439 LEU A 447	ATP A 601 ( 3.7A) ATP A 601 (-2.8A) ATP A 601 ( 3.7A) None None SEP A 474 ( 3.2A) None	0.77A	3zosA-4xbrA: 15.3	3zosA-4xbrA: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOS_B_0LIB1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	ALA A 348 LYS A 350 GLU A 366 LEU A 431 HIS A 438 ARG A 439 LEU A 447	ATP A 601 ( 3.7A) ATP A 601 (-2.8A) ATP A 601 ( 3.7A) None None SEP A 474 ( 3.2A) None	0.82A	3zosB-4xbrA: 15.3	3zosB-4xbrA: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	VAL A 335 ALA A 348 LYS A 350 GLU A 366 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-2.8A) ATP A 601 ( 3.7A) ATP A 601 (-4.6A) None None	0.73A	4ag8A-4xbrA: 17.0	4ag8A-4xbrA: 25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	VAL A 335 ALA A 348 LYS A 350 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None ATP A 601 (-4.6A) None None	0.68A	4ag8A-4xbrA: 17.0	4ag8A-4xbrA: 25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B9Z_A_ACRA1818_1 (ALPHA-GLUCOSIDASE, PUTATIVE, ADG31B)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	ILE A 446 LEU A 398 GLU A 396 PHE A 459 HIS A 438	None ATP A 601 (-4.3A) None None None	1.13A	4b9zA-4xbrA: 2.3	4b9zA-4xbrA: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EB6_C_VLBC503_1 (TUBULIN BETA CHAIN TUBULIN ALPHA CHAIN)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	VAL A 509 THR A 408 ILE A 581 VAL A 420 ILE A 446	None	1.19A	4eb6B-4xbrA: undetectable 4eb6C-4xbrA: undetectable	4eb6B-4xbrA: 22.15 4eb6C-4xbrA: 20.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4KS8_A_B49A701_1 (SERINE/THREONINE-PRO TEIN KINASE PAK 6)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	9 / 10	ALA A 348 VAL A 379 MET A 395 PHE A 397 LEU A 398 GLY A 401 LEU A 447 SER A 457 ASP A 458	ATP A 601 ( 3.7A) None ATP A 601 (-4.3A) ATP A 601 (-4.6A) ATP A 601 (-4.3A) None None ATP A 601 ( 4.6A) ATP A 601 ( 2.5A)	0.68A	4ks8A-4xbrA: 34.2	4ks8A-4xbrA: 62.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4KS8_A_B49A701_1 (SERINE/THREONINE-PRO TEIN KINASE PAK 6)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	9 / 10	ILE A 327 ALA A 348 VAL A 379 MET A 395 PHE A 397 LEU A 398 LEU A 447 SER A 457 ASP A 458	None ATP A 601 ( 3.7A) None ATP A 601 (-4.3A) ATP A 601 (-4.6A) ATP A 601 (-4.3A) None ATP A 601 ( 4.6A) ATP A 601 ( 2.5A)	0.72A	4ks8A-4xbrA: 34.2	4ks8A-4xbrA: 62.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4KS8_A_B49A701_1 (SERINE/THREONINE-PRO TEIN KINASE PAK 6)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 10	VAL A 379 MET A 395 PHE A 397 LEU A 398 GLY A 400 LEU A 447 SER A 457	None ATP A 601 (-4.3A) ATP A 601 (-4.6A) ATP A 601 (-4.3A) None None ATP A 601 ( 4.6A)	1.21A	4ks8A-4xbrA: 34.2	4ks8A-4xbrA: 62.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4QMZ_A_B49A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	ILE A 327 GLY A 328 VAL A 335 ALA A 348 MET A 395 LEU A 398 LEU A 447	None ATP A 601 ( 4.1A) ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-4.3A) ATP A 601 (-4.3A) None	0.54A	4qmzA-4xbrA: 28.2	4qmzA-4xbrA: 33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WBO_B_ANWB601_0 (RHODOPSIN KINASE)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 8	ALA A 348 MET A 395 LEU A 447 SER A 457	ATP A 601 ( 3.7A) ATP A 601 (-4.3A) None ATP A 601 ( 4.6A)	0.51A	4wboB-4xbrA: 24.5	4wboB-4xbrA: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XEY_A_1N1A601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	VAL A 335 ALA A 348 LYS A 350 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None ATP A 601 (-4.6A) None None	0.64A	4xeyA-4xbrA: 20.4	4xeyA-4xbrA: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XEY_B_1N1B601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	VAL A 335 ALA A 348 LYS A 350 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None ATP A 601 (-4.6A) None None	0.66A	4xeyB-4xbrA: 23.8	4xeyB-4xbrA: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CU6_A_ACTA403_0 (CASEIN KINASE II SUBUNIT ALPHA)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 6	TYR A 492 VAL A 496 PRO A 557 ALA A 483	SEP A 474 ( 4.2A) None None None	0.82A	5cu6A-4xbrA: 24.9	5cu6A-4xbrA: 25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I9Y_A_1N1A1001_1 (EPHRIN TYPE-A RECEPTOR 2)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	ALA A 348 LYS A 350 MET A 370 GLY A 401 LEU A 447 SER A 457	ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None None None ATP A 601 ( 4.6A)	0.67A	5i9yA-4xbrA: 18.5	5i9yA-4xbrA: 24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IM2_A_BEZA401_0 (TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	VAL A 407 ILE A 503 PRO A 533 LEU A 535 VAL A 509	None	1.18A	5im2A-4xbrA: undetectable	5im2A-4xbrA: 23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JCN_B_ASCB502_0 (OS09G0567300 PROTEIN)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 6	GLU A 495 PRO A 557 GLY A 493 ARG A 471	None	1.19A	5jcnB-4xbrA: undetectable	5jcnB-4xbrA: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_B_ADNB401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 9	ILE A 327 GLY A 328 VAL A 335 ALA A 348 MET A 395	None ATP A 601 ( 4.1A) ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-4.3A)	0.61A	5lw1B-4xbrA: 16.1	5lw1B-4xbrA: 12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OTR_A_ACTA402_0 (CASEIN KINASE II SUBUNIT ALPHA)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 5	TYR A 492 VAL A 496 PRO A 557 ALA A 483	SEP A 474 ( 4.2A) None None None	0.77A	5otrA-4xbrA: 24.7	5otrA-4xbrA: 25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	ALA A 348 MET A 370 VAL A 379 PHE A 397 GLY A 400 LEU A 447	ATP A 601 ( 3.7A) None None ATP A 601 (-4.6A) None None	1.23A	5te0A-4xbrA: 20.5	5te0A-4xbrA: 25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	ALA A 348 MET A 370 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP A 601 ( 3.7A) None None ATP A 601 (-4.6A) None None	0.76A	5te0A-4xbrA: 20.5	5te0A-4xbrA: 25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB310_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	4 / 4	GLY A 493 PRO A 494 VAL A 465 ARG A 471	None	1.19A	5uunA-4xbrA: undetectable 5uunB-4xbrA: undetectable	5uunA-4xbrA: 21.41 5uunB-4xbrA: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIQ_C_HFGC1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	5 / 12	PRO A 479 THR A 478 TRP A 481 THR A 404 SER A 445	None None None None MG A 603 ( 4.0A)	1.24A	5xiqC-4xbrA: undetectable	5xiqC-4xbrA: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZV2_A_LEVA801_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	3 / 3	LYS A 350 LEU A 447 ASP A 458	ATP A 601 (-2.8A) None ATP A 601 ( 2.5A)	0.84A	5zv2A-4xbrA: 17.9	5zv2A-4xbrA: 16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FNM_A_1N1A1001_1 (-)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	ILE A 327 VAL A 335 ALA A 348 LYS A 350 MET A 370 GLY A 401 LEU A 447	None ATP A 601 (-4.4A) ATP A 601 ( 3.7A) ATP A 601 (-2.8A) None None None	0.89A	6fnmA-4xbrA: 19.2	6fnmA-4xbrA: 26.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICR_A_NIOA604_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"SER A 443;THR A 404;GLU A 507;GLY A 511","None","0.89A","1icrA-4xbrA:undetectable;1icrB-4xbrA:undetectable","1icrA-4xbrA:21.35;1icrB-4xbrA:21.35"],["1ICR_B_NIOB602_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"GLU A 507;GLY A 511;SER A 443;THR A 404","None","0.89A","1icrA-4xbrA:undetectable;1icrB-4xbrA:undetectable","1icrA-4xbrA:21.35;1icrB-4xbrA:21.35"],["1ICU_A_NIOA221_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"SER A 443;THR A 404;GLU A 507;GLY A 511","None","0.93A","1icuA-4xbrA:undetectable;1icuB-4xbrA:undetectable","1icuA-4xbrA:21.35;1icuB-4xbrA:21.35"],["1ICU_B_NIOB219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"GLU A 507;GLY A 511;SER A 443;THR A 404","None","0.92A","1icuA-4xbrA:undetectable;1icuB-4xbrA:undetectable","1icuA-4xbrA:21.35;1icuB-4xbrA:21.35"],["1ICU_C_NIOC225_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"SER A 443;THR A 404;GLU A 507;GLY A 511","None","0.93A","1icuC-4xbrA:undetectable;1icuD-4xbrA:undetectable","1icuC-4xbrA:21.35;1icuD-4xbrA:21.35"],["1ICV_C_NIOC708_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"SER A 443;THR A 404;GLU A 507;GLY A 511","None","0.91A","1icvC-4xbrA:undetectable;1icvD-4xbrA:undetectable","1icvC-4xbrA:21.35;1icvD-4xbrA:21.35"],["1ICV_D_NIOD706_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"GLU A 507;GLY A 511;SER A 443;THR A 404","None","0.95A","1icvC-4xbrA:undetectable;1icvD-4xbrA:undetectable","1icvC-4xbrA:21.35;1icvD-4xbrA:21.35"],["1KQB_A_BEZA524_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"SER A 443;THR A 404;GLU A 507;GLY A 511","None","0.91A","1kqbA-4xbrA:undetectable;1kqbB-4xbrA:undetectable","1kqbA-4xbrA:20.54;1kqbB-4xbrA:20.54"],["1KQB_B_BEZB525_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"GLU A 507;GLY A 511;SER A 443;THR A 404","None","0.93A","1kqbA-4xbrA:undetectable;1kqbB-4xbrA:undetectable","1kqbA-4xbrA:20.54;1kqbB-4xbrA:20.54"],["1KQB_C_BEZC522_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"SER A 443;THR A 404;GLU A 507;GLY A 511","None","0.88A","1kqbC-4xbrA:undetectable;1kqbD-4xbrA:undetectable","1kqbC-4xbrA:20.54;1kqbD-4xbrA:20.54"],["1KQB_D_BEZD523_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"GLU A 507;GLY A 511;SER A 443;THR A 404","None","0.89A","1kqbC-4xbrA:undetectable;1kqbD-4xbrA:undetectable","1kqbC-4xbrA:20.54;1kqbD-4xbrA:20.54"],["1MOG_A_RBFA200_1","DODECIN","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",3,"PHE A 324;TRP A 392;GLU A 390","None","0.85A","1mogA-4xbrA:undetectable","1mogA-4xbrA:13.17"],["1MX1_B_THAB2_1","LIVER CARBOXYLESTERASE I","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"PHE A 548;VAL A 407;LEU A 403;LEU A 552;LEU A 501","None","1.34A","1mx1B-4xbrA:undetectable","1mx1B-4xbrA:20.47"],["2AA6_B_STRB402_1","MINERALOCORTICOID RECEPTOR","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"ASN A 377;LEU A 456;ALA A 427;LEU A 501;LEU A 572","None","1.14A","2aa6B-4xbrA:undetectable","2aa6B-4xbrA:19.95"],["2CC8_A_RBFA1067_1","VNG1446H","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",3,"PHE A 324;VAL A 349;TRP A 392","None","0.85A","2cc8A-4xbrA:undetectable","2cc8A-4xbrA:13.17"],["2CCB_A_RBFA1067_1","VNG1446H","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",3,"PHE A 324;VAL A 349;TRP A 392","None","0.85A","2ccbA-4xbrA:undetectable","2ccbA-4xbrA:13.17"],["2EVA_A_ADNA498_1","TAK1 KINASE - TAB1 CHIMERA FUSION PROTEIN","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"GLY A 328;GLY A 330;VAL A 335;ALA A 348;MET A 395;LEU A 447","ATP A 601 ( 4.1A);ATP A 601 (-3.4A);ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-4.3A);None","0.56A","2evaA-4xbrA:17.7","2evaA-4xbrA:24.88"],["2GQG_A_1N1A501_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"ALA A 348;LYS A 350;MET A 370;VAL A 379;PHE A 397;GLY A 401;LEU A 447","ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;None;ATP A 601 (-4.6A);None;None","0.76A","2gqgA-4xbrA:21.2","2gqgA-4xbrA:22.05"],["2HYY_A_STIA600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"VAL A 335;ALA A 348;GLU A 366;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 ( 3.7A);ATP A 601 (-4.6A);None;None","0.77A","2hyyA-4xbrA:16.7","2hyyA-4xbrA:21.58"],["2HYY_B_STIB600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"VAL A 335;ALA A 348;GLU A 366;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 ( 3.7A);ATP A 601 (-4.6A);None;None","0.69A","2hyyB-4xbrA:16.7","2hyyB-4xbrA:21.58"],["2HYY_C_STIC600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"VAL A 335;ALA A 348;GLU A 366;VAL A 379;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 ( 3.7A);None;ATP A 601 (-4.6A);None;None","0.81A","2hyyC-4xbrA:16.6","2hyyC-4xbrA:21.58"],["2ITY_A_IREA2020_1","EPIDERMAL GROWTH FACTOR RECEPTOR","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",8,"GLY A 328;VAL A 335;ALA A 348;LYS A 350;MET A 370;GLY A 401;LEU A 447;ASP A 458","ATP A 601 ( 4.1A);ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;None;None;ATP A 601 ( 2.5A)","0.56A","2ityA-4xbrA:19.9","2ityA-4xbrA:26.77"],["2ITZ_A_IREA2021_1","EPIDERMAL GROWTH FACTOR RECEPTOR","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"VAL A 335;ALA A 348;LYS A 350;MET A 370;GLY A 401;LEU A 447;ASP A 458","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;None;None;ATP A 601 ( 2.5A)","0.66A","2itzA-4xbrA:20.0","2itzA-4xbrA:25.59"],["2OAX_D_SNLD4001_1","MINERALOCORTICOID RECEPTOR","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"ASN A 377;LEU A 456;ALA A 427;LEU A 501;LEU A 572","None","1.14A","2oaxD-4xbrA:undetectable","2oaxD-4xbrA:18.85"],["2OAX_E_SNLE5001_1","MINERALOCORTICOID RECEPTOR","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"ASN A 377;LEU A 456;ALA A 427;LEU A 501;LEU A 572","None","1.17A","2oaxE-4xbrA:undetectable","2oaxE-4xbrA:18.85"],["2VX9_A_RBFA1064_1","DODECIN","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",3,"PHE A 324;VAL A 349;TRP A 392","None","0.83A","2vx9A-4xbrA:undetectable","2vx9A-4xbrA:12.87"],["2Y00_B_Y00B601_1","BETA-1 ADRENERGIC RECEPTOR","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"LEU A 456;VAL A 424;ASP A 444;SER A 180;PHE A 516","None","1.29A","2y00B-4xbrA:undetectable","2y00B-4xbrA:22.11"],["2Y01_B_Y00B601_1","BETA-1 ADRENERGIC RECEPTOR","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"LEU A 456;VAL A 424;ASP A 444;SER A 180;PHE A 516","None","1.25A","2y01B-4xbrA:undetectable","2y01B-4xbrA:22.11"],["2Y6O_A_1N1A1892_1","EPHRIN TYPE-A RECEPTOR 4","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"ILE A 327;ALA A 348;LYS A 350;MET A 370;GLY A 401;LEU A 447;SER A 457","None;ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;None;None;ATP A 601 ( 4.6A)","0.81A","2y6oA-4xbrA:17.3","2y6oA-4xbrA:24.46"],["3C7Q_A_XINA1172_1","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"GLY A 328;ALA A 348;LYS A 350;VAL A 379;PHE A 397;GLY A 401;LEU A 447","ATP A 601 ( 4.1A);ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;ATP A 601 (-4.6A);None;None","0.54A","3c7qA-4xbrA:17.5","3c7qA-4xbrA:25.97"],["3K2H_A_LYAA514_1","DIHYDROFOLATE REDUCTASE\/THYMIDYLATE SYNTHASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"ALA A 463;ILE A 441;SER A 445;LEU A 456;LEU A 431","SEP A 474 ( 4.1A);None; MG A 603 ( 4.0A);None;None","1.06A","3k2hA-4xbrA:undetectable","3k2hA-4xbrA:21.94"],["3K5V_A_STIA2_1","TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"VAL A 335;ALA A 348;GLU A 366;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 ( 3.7A);ATP A 601 (-4.6A);None;None","0.68A","3k5vA-4xbrA:16.0","3k5vA-4xbrA:20.05"],["3K5V_B_STIB2_1","TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"VAL A 335;ALA A 348;GLU A 366;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 ( 3.7A);ATP A 601 (-4.6A);None;None","0.68A","3k5vB-4xbrA:16.0","3k5vB-4xbrA:20.05"],["3MIY_A_B49A1_1","TYROSINE-PROTEIN KINASE ITK\/TSK","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",8,"ILE A 327;ALA A 348;LYS A 350;VAL A 379;PHE A 397;LEU A 447;SER A 457;ASP A 458","None;ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;ATP A 601 (-4.6A);None;ATP A 601 ( 4.6A);ATP A 601 ( 2.5A)","0.84A","3miyA-4xbrA:19.4","3miyA-4xbrA:24.22"],["3MIY_A_B49A1_1","TYROSINE-PROTEIN KINASE ITK\/TSK","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"LYS A 350;VAL A 379;PHE A 397;GLY A 401;LEU A 447;SER A 457;ASP A 458","ATP A 601 (-2.8A);None;ATP A 601 (-4.6A);None;None;ATP A 601 ( 4.6A);ATP A 601 ( 2.5A)","0.85A","3miyA-4xbrA:19.4","3miyA-4xbrA:24.22"],["3MIY_B_B49B2_1","TYROSINE-PROTEIN KINASE ITK\/TSK","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"ILE A 327;ALA A 348;LYS A 350;PHE A 397;LEU A 447;SER A 457","None;ATP A 601 ( 3.7A);ATP A 601 (-2.8A);ATP A 601 (-4.6A);None;ATP A 601 ( 4.6A)","0.73A","3miyB-4xbrA:22.7","3miyB-4xbrA:24.22"],["3MS9_B_STIB1_1","TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"VAL A 335;ALA A 348;GLU A 366;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 ( 3.7A);ATP A 601 (-4.6A);None;None","0.67A","3ms9B-4xbrA:16.5","3ms9B-4xbrA:20.05"],["3MSS_B_STIB1_1","TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"VAL A 335;ALA A 348;GLU A 366;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 ( 3.7A);ATP A 601 (-4.6A);None;None","0.65A","3mssB-4xbrA:16.7","3mssB-4xbrA:20.05"],["3PYY_A_STIA3_1","V-ABL ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 ISOFORM B VARIANT","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"VAL A 335;ALA A 348;GLU A 366;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 ( 3.7A);ATP A 601 (-4.6A);None;None","0.78A","3pyyA-4xbrA:16.7","3pyyA-4xbrA:19.74"],["3RF4_A_FUNA201_1","MACROPHAGE MIGRATION INHIBITORY FACTOR;MACROPHAGE MIGRATION INHIBITORY FACTOR","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"MET A 508;SER A 443;ILE A 446;VAL A 420;VAL A 454","None","1.31A","3rf4A-4xbrA:undetectable;3rf4C-4xbrA:undetectable","3rf4A-4xbrA:15.84;3rf4C-4xbrA:15.84"],["3RF4_B_FUNB202_1","MACROPHAGE MIGRATION INHIBITORY FACTOR;MACROPHAGE MIGRATION INHIBITORY FACTOR","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"MET A 508;SER A 443;ILE A 446;VAL A 420;VAL A 454","None","1.33A","3rf4A-4xbrA:undetectable;3rf4B-4xbrA:undetectable","3rf4A-4xbrA:15.84;3rf4B-4xbrA:15.84"],["3SXR_B_1N1B2_1","CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"VAL A 335;ALA A 348;MET A 370;VAL A 379;GLY A 401;LEU A 447;SER A 457","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);None;None;None;None;ATP A 601 ( 4.6A)","0.83A","3sxrB-4xbrA:19.5","3sxrB-4xbrA:24.47"],["3UE4_A_DB8A601_1","TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"ALA A 348;LYS A 350;GLU A 366;VAL A 379;PHE A 397;GLY A 401;LEU A 447","ATP A 601 ( 3.7A);ATP A 601 (-2.8A);ATP A 601 ( 3.7A);None;ATP A 601 (-4.6A);None;None","0.76A","3ue4A-4xbrA:20.5","3ue4A-4xbrA:21.20"],["3UE4_B_DB8B601_1","TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",8,"VAL A 335;ALA A 348;GLU A 366;MET A 370;VAL A 379;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 ( 3.7A);None;None;ATP A 601 (-4.6A);None;None","0.87A","3ue4B-4xbrA:18.5","3ue4B-4xbrA:21.20"],["3WZD_A_LEVA1201_2","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"ILE A 369;VAL A 379;LEU A 447;ASP A 458","None;None;None;ATP A 601 ( 2.5A)","0.74A","3wzdA-4xbrA:17.9","3wzdA-4xbrA:24.62"],["3WZD_A_LEVA1201_2","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"LYS A 350;ILE A 369;VAL A 379;ASP A 458","ATP A 601 (-2.8A);None;None;ATP A 601 ( 2.5A)","1.04A","3wzdA-4xbrA:17.9","3wzdA-4xbrA:24.62"],["3ZOS_A_0LIA1000_1","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"ALA A 348;LYS A 350;GLU A 366;LEU A 431;HIS A 438;ARG A 439;LEU A 447","ATP A 601 ( 3.7A);ATP A 601 (-2.8A);ATP A 601 ( 3.7A);None;None;SEP A 474 ( 3.2A);None","0.77A","3zosA-4xbrA:15.3","3zosA-4xbrA:23.56"],["3ZOS_B_0LIB1000_1","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"ALA A 348;LYS A 350;GLU A 366;LEU A 431;HIS A 438;ARG A 439;LEU A 447","ATP A 601 ( 3.7A);ATP A 601 (-2.8A);ATP A 601 ( 3.7A);None;None;SEP A 474 ( 3.2A);None","0.82A","3zosB-4xbrA:15.3","3zosB-4xbrA:23.56"],["4AG8_A_AXIA2000_1","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"VAL A 335;ALA A 348;LYS A 350;GLU A 366;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-2.8A);ATP A 601 ( 3.7A);ATP A 601 (-4.6A);None;None","0.73A","4ag8A-4xbrA:17.0","4ag8A-4xbrA:25.44"],["4AG8_A_AXIA2000_1","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"VAL A 335;ALA A 348;LYS A 350;VAL A 379;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;ATP A 601 (-4.6A);None;None","0.68A","4ag8A-4xbrA:17.0","4ag8A-4xbrA:25.44"],["4B9Z_A_ACRA1818_1","ALPHA-GLUCOSIDASE, PUTATIVE, ADG31B","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"ILE A 446;LEU A 398;GLU A 396;PHE A 459;HIS A 438","None;ATP A 601 (-4.3A);None;None;None","1.13A","4b9zA-4xbrA:2.3","4b9zA-4xbrA:18.06"],["4EB6_C_VLBC503_1","TUBULIN BETA CHAIN;TUBULIN ALPHA CHAIN","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"VAL A 509;THR A 408;ILE A 581;VAL A 420;ILE A 446","None","1.19A","4eb6B-4xbrA:undetectable;4eb6C-4xbrA:undetectable","4eb6B-4xbrA:22.15;4eb6C-4xbrA:20.63"],["4KS8_A_B49A701_1","SERINE\/THREONINE-PROTEIN KINASE PAK 6","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",9,"ALA A 348;VAL A 379;MET A 395;PHE A 397;LEU A 398;GLY A 401;LEU A 447;SER A 457;ASP A 458","ATP A 601 ( 3.7A);None;ATP A 601 (-4.3A);ATP A 601 (-4.6A);ATP A 601 (-4.3A);None;None;ATP A 601 ( 4.6A);ATP A 601 ( 2.5A)","0.68A","4ks8A-4xbrA:34.2","4ks8A-4xbrA:62.71"],["4KS8_A_B49A701_1","SERINE\/THREONINE-PROTEIN KINASE PAK 6","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",9,"ILE A 327;ALA A 348;VAL A 379;MET A 395;PHE A 397;LEU A 398;LEU A 447;SER A 457;ASP A 458","None;ATP A 601 ( 3.7A);None;ATP A 601 (-4.3A);ATP A 601 (-4.6A);ATP A 601 (-4.3A);None;ATP A 601 ( 4.6A);ATP A 601 ( 2.5A)","0.72A","4ks8A-4xbrA:34.2","4ks8A-4xbrA:62.71"],["4KS8_A_B49A701_1","SERINE\/THREONINE-PROTEIN KINASE PAK 6","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"VAL A 379;MET A 395;PHE A 397;LEU A 398;GLY A 400;LEU A 447;SER A 457","None;ATP A 601 (-4.3A);ATP A 601 (-4.6A);ATP A 601 (-4.3A);None;None;ATP A 601 ( 4.6A)","1.21A","4ks8A-4xbrA:34.2","4ks8A-4xbrA:62.71"],["4QMZ_A_B49A401_1","SERINE\/THREONINE-PROTEIN KINASE 24","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"ILE A 327;GLY A 328;VAL A 335;ALA A 348;MET A 395;LEU A 398;LEU A 447","None;ATP A 601 ( 4.1A);ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-4.3A);ATP A 601 (-4.3A);None","0.54A","4qmzA-4xbrA:28.2","4qmzA-4xbrA:33.33"],["4WBO_B_ANWB601_0","RHODOPSIN KINASE","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"ALA A 348;MET A 395;LEU A 447;SER A 457","ATP A 601 ( 3.7A);ATP A 601 (-4.3A);None;ATP A 601 ( 4.6A)","0.51A","4wboB-4xbrA:24.5","4wboB-4xbrA:23.32"],["4XEY_A_1N1A601_1","TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"VAL A 335;ALA A 348;LYS A 350;VAL A 379;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;ATP A 601 (-4.6A);None;None","0.64A","4xeyA-4xbrA:20.4","4xeyA-4xbrA:22.51"],["4XEY_B_1N1B601_1","TYROSINE-PROTEIN KINASE ABL1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"VAL A 335;ALA A 348;LYS A 350;VAL A 379;PHE A 397;GLY A 401;LEU A 447","ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;ATP A 601 (-4.6A);None;None","0.66A","4xeyB-4xbrA:23.8","4xeyB-4xbrA:22.51"],["5CU6_A_ACTA403_0","CASEIN KINASE II SUBUNIT ALPHA","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"TYR A 492;VAL A 496;PRO A 557;ALA A 483","SEP A 474 ( 4.2A);None;None;None","0.82A","5cu6A-4xbrA:24.9","5cu6A-4xbrA:25.19"],["5I9Y_A_1N1A1001_1","EPHRIN TYPE-A RECEPTOR 2","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"ALA A 348;LYS A 350;MET A 370;GLY A 401;LEU A 447;SER A 457","ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;None;None;ATP A 601 ( 4.6A)","0.67A","5i9yA-4xbrA:18.5","5i9yA-4xbrA:24.63"],["5IM2_A_BEZA401_0","TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"VAL A 407;ILE A 503;PRO A 533;LEU A 535;VAL A 509","None","1.18A","5im2A-4xbrA:undetectable","5im2A-4xbrA:23.09"],["5JCN_B_ASCB502_0","OS09G0567300 PROTEIN","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"GLU A 495;PRO A 557;GLY A 493;ARG A 471","None","1.19A","5jcnB-4xbrA:undetectable","5jcnB-4xbrA:21.14"],["5LW1_B_ADNB401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"ILE A 327;GLY A 328;VAL A 335;ALA A 348;MET A 395","None;ATP A 601 ( 4.1A);ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-4.3A)","0.61A","5lw1B-4xbrA:16.1","5lw1B-4xbrA:12.99"],["5OTR_A_ACTA402_0","CASEIN KINASE II SUBUNIT ALPHA","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"TYR A 492;VAL A 496;PRO A 557;ALA A 483","SEP A 474 ( 4.2A);None;None;None","0.77A","5otrA-4xbrA:24.7","5otrA-4xbrA:25.18"],["5TE0_A_XINA401_1","AP2-ASSOCIATED PROTEIN KINASE 1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"ALA A 348;MET A 370;VAL A 379;PHE A 397;GLY A 400;LEU A 447","ATP A 601 ( 3.7A);None;None;ATP A 601 (-4.6A);None;None","1.23A","5te0A-4xbrA:20.5","5te0A-4xbrA:25.64"],["5TE0_A_XINA401_1","AP2-ASSOCIATED PROTEIN KINASE 1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",6,"ALA A 348;MET A 370;VAL A 379;PHE A 397;GLY A 401;LEU A 447","ATP A 601 ( 3.7A);None;None;ATP A 601 (-4.6A);None;None","0.76A","5te0A-4xbrA:20.5","5te0A-4xbrA:25.64"],["5UUN_B_ACTB310_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",4,"GLY A 493;PRO A 494;VAL A 465;ARG A 471","None","1.19A","5uunA-4xbrA:undetectable;5uunB-4xbrA:undetectable","5uunA-4xbrA:21.41;5uunB-4xbrA:21.41"],["5XIQ_C_HFGC1002_0","PROLYL-TRNA SYNTHETASE (PRORS)","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",5,"PRO A 479;THR A 478;TRP A 481;THR A 404;SER A 445","None;None;None;None; MG A 603 ( 4.0A)","1.24A","5xiqC-4xbrA:undetectable","5xiqC-4xbrA:22.20"],["5ZV2_A_LEVA801_2","FIBROBLAST GROWTH FACTOR RECEPTOR 1","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",3,"LYS A 350;LEU A 447;ASP A 458","ATP A 601 (-2.8A);None;ATP A 601 ( 2.5A)","0.84A","5zv2A-4xbrA:17.9","5zv2A-4xbrA:16.61"],["6FNM_A_1N1A1001_1","-","4xbr","PROTEIN FAM212A,SERINE\/THREONINE-PROTEIN KINASE PAK 4","Homo sapiens",7,"ILE A 327;VAL A 335;ALA A 348;LYS A 350;MET A 370;GLY A 401;LEU A 447","None;ATP A 601 (-4.4A);ATP A 601 ( 3.7A);ATP A 601 (-2.8A);None;None;None","0.89A","6fnmA-4xbrA:19.2","6fnmA-4xbrA:26.67"]]