SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xcr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		4 / 5 ASP A  71
VAL A  29
SER A  75
ASP A  53
 None
 1.31A 1n2xB-4xcrA:
undetectable		 1n2xB-4xcrA:
17.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		4 / 6 GLU A  21
PRO A  28
LYS A  30
GLU A  70
 None
 0.64A 4a7tA-4xcrA:
15.9		 4a7tA-4xcrA:
67.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		4 / 6 LYS A  23
PRO A  28
LYS A  30
GLU A  70
 None
 0.87A 4a7tA-4xcrA:
15.9		 4a7tA-4xcrA:
67.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		4 / 6 GLU A  21
PRO A  28
LYS A  30
GLU A  70
 None
 0.73A 4a7tF-4xcrA:
16.2		 4a7tF-4xcrA:
67.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7U_A_ALEA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		4 / 6 GLU A  21
PRO A  28
LYS A  30
GLU A  70
 None
 0.67A 4a7uA-4xcrA:
16.0		 4a7uA-4xcrA:
67.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7U_A_ALEA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		4 / 6 LYS A  23
PRO A  28
LYS A  30
GLU A  70
 None
 0.74A 4a7uA-4xcrA:
16.0		 4a7uA-4xcrA:
67.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		4 / 5 VAL A  47
LEU A  87
ILE A 106
VAL A  29
 None
 0.97A 4a9kB-4xcrA:
undetectable		 4a9kB-4xcrA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		4 / 8 LEU A  54
VAL A  31
VAL A  29
GLN A  22
 None
 0.93A 4em2A-4xcrA:
undetectable		 4em2A-4xcrA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		5 / 12 ILE A 106
ALA A   4
ILE A  18
ALA A   6
VAL A  31
 None
 1.05A 5n0tB-4xcrA:
undetectable		 5n0tB-4xcrA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		5 / 12 ILE A 106
GLY A 107
ILE A 108
ILE A  74
ILE A  82
 None
 1.05A 6emuB-4xcrA:
undetectable		 6emuB-4xcrA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4xcr SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens) 		5 / 12 ILE A 106
GLY A 107
ILE A 108
ILE A  74
ILE A  82
 None
 1.05A 6emuC-4xcrA:
undetectable		 6emuC-4xcrA:
19.60