SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xe7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 6 PHE A 246
ILE A 234
LYS A 366
ALA A 364
 None
 1.02A 1hk2A-4xe7A:
undetectable		 1hk2A-4xe7A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		5 / 11 GLY A 377
GLY A 373
LEU A 237
ASP A 383
LEU A 345
 None
 1.10A 1jg3A-4xe7A:
undetectable		 1jg3A-4xe7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		5 / 11 GLY A 377
GLY A 373
LEU A 237
ASP A 383
LEU A 345
 None
 1.11A 1jg3B-4xe7A:
undetectable		 1jg3B-4xe7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 7 VAL A 374
GLY A 373
ILE A 316
VAL A 312
 None
 0.81A 1p2yA-4xe7A:
undetectable		 1p2yA-4xe7A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		5 / 11 LEU A  82
ILE A 167
LEU A 171
THR A  17
HIS A 126
 None
 1.10A 1tw4A-4xe7A:
undetectable		 1tw4A-4xe7A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 5 ILE A 391
LEU A 210
ALA A 226
GLU A 230
 None
 1.27A 1xvaA-4xe7A:
undetectable
1xvaB-4xe7A:
undetectable		 1xvaA-4xe7A:
20.74
1xvaB-4xe7A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		6 / 12 GLY A 238
ASN A 235
THR A 260
GLY A 380
LEU A 381
LEU A 384
 None
 1.31A 2hw2A-4xe7A:
undetectable		 2hw2A-4xe7A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 6 ARG A 162
ASP A 158
ILE A 156
GLU A 201
 None
 1.35A 2ya7C-4xe7A:
undetectable		 2ya7C-4xe7A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		5 / 12 LEU A  73
ILE A  38
ILE A 128
ILE A  24
ALA A 135
 None
 1.08A 3uj7A-4xe7A:
undetectable		 3uj7A-4xe7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 5 TYR A 401
SER A 133
ASP A 212
ILE A 213
 None
 1.31A 3uj7B-4xe7A:
undetectable		 3uj7B-4xe7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		5 / 12 GLY A 142
LYS A 187
ILE A 189
VAL A 177
LEU A  11
 None
 1.21A 4a81A-4xe7A:
undetectable		 4a81A-4xe7A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 5 THR A 176
ILE A 189
LYS A 188
GLU A 144
 None
 1.29A 4ac9C-4xe7A:
undetectable		 4ac9C-4xe7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 5 THR A 176
ILE A 189
LYS A 188
GLU A 144
 None
 1.29A 4acaC-4xe7A:
undetectable		 4acaC-4xe7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 5 THR A 176
ILE A 189
LYS A 188
GLU A 144
 None
 1.36A 4acbC-4xe7A:
undetectable		 4acbC-4xe7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		5 / 12 GLY A 372
GLY A 373
TYR A 347
ILE A 396
GLN A 305
 None
 1.25A 4fglA-4xe7A:
undetectable
4fglB-4xe7A:
undetectable		 4fglA-4xe7A:
19.81
4fglB-4xe7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 5 VAL A 327
VAL A 332
GLY A 330
PHE A 279
 None
 1.10A 5d4nA-4xe7A:
undetectable
5d4nC-4xe7A:
undetectable		 5d4nA-4xe7A:
14.36
5d4nC-4xe7A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		5 / 10 THR A 197
GLY A 152
GLY A 153
SER A 204
ALA A 410
 None
 1.01A 5l0zB-4xe7A:
undetectable		 5l0zB-4xe7A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		3 / 3 ARG A  87
ILE A  78
SER A  79
 None
 0.89A 5zw2A-4xe7A:
undetectable		 5zw2A-4xe7A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 4xe7 UNCHARACTERIZED
PROTEIN
(Bacillus
thuringiensis) 		4 / 5 ARG A  89
ALA A  90
GLN A 104
ILE A  42
 None
 1.36A 6g9bA-4xe7A:
undetectable
6g9bB-4xe7A:
0.7		 6g9bA-4xe7A:
12.11
6g9bB-4xe7A:
10.72