SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xeu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_B_MTXB171_1
(DIHYDROFOLATE
REDUCTASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 337
ARG A 509
GLU A 373
ILE A 428
LEU A 456
 None
 1.14A 1d1gB-4xeuA:
undetectable		 1d1gB-4xeuA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 213
ALA A 231
LEU A  40
ALA A 151
ILE A 240
 None
 1.28A 1g5yB-4xeuA:
undetectable		 1g5yB-4xeuA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 4 GLY A  28
ASP A 183
GLY A 156
THR A 113
 None
 1.03A 1hxbB-4xeuA:
undetectable		 1hxbB-4xeuA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.33A 1kifA-4xeuA:
undetectable		 1kifA-4xeuA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.33A 1kifB-4xeuA:
undetectable		 1kifB-4xeuA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.33A 1kifC-4xeuA:
undetectable		 1kifC-4xeuA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.33A 1kifD-4xeuA:
undetectable		 1kifD-4xeuA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.33A 1kifE-4xeuA:
undetectable		 1kifE-4xeuA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.33A 1kifF-4xeuA:
undetectable		 1kifF-4xeuA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.33A 1kifG-4xeuA:
undetectable		 1kifG-4xeuA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.33A 1kifH-4xeuA:
undetectable		 1kifH-4xeuA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 ASN A 138
ALA A 134
ASP A 146
GLU A 130
 None
 1.24A 1lqtA-4xeuA:
3.6
1lqtB-4xeuA:
3.7		 1lqtA-4xeuA:
21.21
1lqtB-4xeuA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 ASN A 138
ALA A 134
ASP A 146
GLU A 130
 None
 1.24A 1lquA-4xeuA:
2.8
1lquB-4xeuA:
3.3		 1lquA-4xeuA:
21.21
1lquB-4xeuA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 123
GLY A 125
LEU A 153
ALA A 151
LEU A 178
 None
 1.12A 1mjqI-4xeuA:
undetectable
1mjqJ-4xeuA:
undetectable		 1mjqI-4xeuA:
11.13
1mjqJ-4xeuA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.31A 1ve9A-4xeuA:
undetectable		 1ve9A-4xeuA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  40
PRO A  52
ILE A  71
LEU A  74
 None
EDO  A 701 (-4.8A)
None
None
 1.07A 1ya4C-4xeuA:
undetectable		 1ya4C-4xeuA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 6 LEU A 601
TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.20A 2du8A-4xeuA:
undetectable		 2du8A-4xeuA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 6 LEU A 601
TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.20A 2du8B-4xeuA:
2.5		 2du8B-4xeuA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.33A 2du8G-4xeuA:
2.5		 2du8G-4xeuA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 589
TYR A 622
ILE A 555
GLY A 539
 None
 1.24A 2du8J-4xeuA:
3.1		 2du8J-4xeuA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLN A 361
ALA A 363
TYR A 430
GLY A 376
LEU A 375
 None
 1.27A 2nv4A-4xeuA:
undetectable		 2nv4A-4xeuA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 6 THR A 586
ARG A 483
THR A 557
ASP A 545
 None
 1.33A 2okcA-4xeuA:
undetectable		 2okcA-4xeuA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 4 ALA A 610
TYR A 622
ALA A 616
TYR A 618
 None
 1.23A 2wlkA-4xeuA:
undetectable
2wlkB-4xeuA:
undetectable		 2wlkA-4xeuA:
16.00
2wlkB-4xeuA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 8 MET A 632
ALA A 639
HIS A 647
GLU A 637
 None
 0.88A 2x0pA-4xeuA:
undetectable		 2x0pA-4xeuA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  37
GLY A  32
GLY A 218
ILE A 224
HIS A 219
 None
 1.12A 2x1lA-4xeuA:
undetectable		 2x1lA-4xeuA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 4 TYR A  80
LEU A  82
LEU A  75
HIS A  47
 None
 1.16A 2x7hB-4xeuA:
undetectable		 2x7hB-4xeuA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 212
CYH A 241
CYH A 242
HIS A 219
VAL A 245
 None
 1.23A 3g8iA-4xeuA:
undetectable		 3g8iA-4xeuA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 4 GLY A  28
ASP A 183
GLY A 156
THR A 113
 None
 1.05A 3k4vC-4xeuA:
undetectable		 3k4vC-4xeuA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP4_A_MIIA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 9 THR A 172
LEU A 169
ALA A 167
HIS A 164
ARG A 410
 None
 1.41A 3kp4A-4xeuA:
0.0
3kp4B-4xeuA:
0.0		 3kp4A-4xeuA:
13.18
3kp4B-4xeuA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 172
LEU A 169
ALA A 167
ARG A 410
 None
 1.04A 3kp6A-4xeuA:
undetectable		 3kp6A-4xeuA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 408
ARG A 442
PHE A 412
ALA A 441
ALA A 444
SER A 448
 None
 1.36A 3sudA-4xeuA:
undetectable		 3sudA-4xeuA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 ALA A 151
MET A  33
PHE A  60
ASN A  64
 None
 1.47A 3uq6A-4xeuA:
undetectable		 3uq6A-4xeuA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 ALA A 227
GLY A 218
CYH A 242
LYS A 243
 None
 1.49A 3zwiA-4xeuA:
undetectable		 3zwiA-4xeuA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		3 / 3 ASN A   9
TRP A 278
ASP A  35
 None
 1.14A 4a7tA-4xeuA:
undetectable
4a7tF-4xeuA:
undetectable		 4a7tA-4xeuA:
13.44
4a7tF-4xeuA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 8 GLY A  28
GLY A  67
VAL A  19
HIS A 100
 None
 0.68A 4c5nC-4xeuA:
undetectable		 4c5nC-4xeuA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 12 THR A 172
LEU A 169
ALA A 167
HIS A 164
ARG A 410
 None
 1.39A 4ejwA-4xeuA:
undetectable		 4ejwA-4xeuA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 101
TYR A  72
GLY A  67
 None
 0.75A 4g2zA-4xeuA:
undetectable		 4g2zA-4xeuA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  70
ILE A  11
ARG A  12
 None
 0.58A 4mk4B-4xeuA:
2.2		 4mk4B-4xeuA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_2
(ANDROGEN RECEPTOR)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 4 ASN A  89
MET A  69
LEU A  82
HIS A  76
 None
 1.26A 4oktA-4xeuA:
0.0		 4oktA-4xeuA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 VAL A 144
TYR A  44
ILE A  36
THR A 238
 None
 1.28A 4ze1A-4xeuA:
0.0		 4ze1A-4xeuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 VAL A 144
TYR A  44
ILE A 224
THR A 238
 None
 1.33A 4ze1A-4xeuA:
0.0		 4ze1A-4xeuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 565
GLN A 526
LEU A 543
SER A 582
 None
 1.07A 4zphA-4xeuA:
undetectable
4zphB-4xeuA:
undetectable		 4zphA-4xeuA:
19.64
4zphB-4xeuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 7 ARG A   5
VAL A  39
HIS A 219
GLU A 223
 None
None
None
CA  A 702 (-2.6A)
 1.34A 5ad9A-4xeuA:
undetectable
5ad9B-4xeuA:
undetectable		 5ad9A-4xeuA:
19.62
5ad9B-4xeuA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 9 ILE A 428
PRO A 429
MET A 418
LEU A 516
LEU A 332
 None
 1.37A 5iepA-4xeuA:
undetectable		 5iepA-4xeuA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 ALA A 227
GLY A 218
CYH A 242
LYS A 243
 None
 1.50A 5jt4A-4xeuA:
undetectable		 5jt4A-4xeuA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 10 TYR A 618
TYR A 622
ILE A 555
TYR A 620
ILE A 629
 None
 1.33A 5mzrA-4xeuA:
undetectable		 5mzrA-4xeuA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 10 TYR A 618
TYR A 622
ILE A 555
TYR A 620
ILE A 629
 None
 1.31A 5mzrC-4xeuA:
undetectable		 5mzrC-4xeuA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 5 ALA A  37
VAL A  39
PHE A 152
ILE A 228
 None
 1.02A 5of1A-4xeuA:
undetectable		 5of1A-4xeuA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 7 ASP A 183
ASP A 155
GLY A 156
ASN A  64
 None
 1.05A 5x7pA-4xeuA:
undetectable		 5x7pA-4xeuA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 394
TYR A 404
LEU A 173
VAL A 132
 None
 0.97A 5x80A-4xeuA:
undetectable
5x80B-4xeuA:
undetectable		 5x80A-4xeuA:
13.97
5x80B-4xeuA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  65
VAL A 109
GLY A 154
ALA A 151
ALA A 180
 None
 1.00A 6c2mD-4xeuA:
undetectable		 6c2mD-4xeuA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 4xeu TRANSKETOLASE
(Pseudomonas
aeruginosa) 		4 / 4 MET A  31
GLY A  28
HIS A  26
GLY A 247
 None
 1.42A 6fgdA-4xeuA:
3.7		 6fgdA-4xeuA:
21.54