SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 7 ASP A 219
GLY A  26
GLY A  25
GLN A 136
INS  A 301 (-2.7A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
MG  A 303 ( 2.9A)
0.96A 1ekjE-4xf7A:
undetectable
1ekjF-4xf7A:
undetectable
1ekjE-4xf7A:
23.49
1ekjF-4xf7A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 8 ASP A 219
GLY A  26
GLY A  25
GLN A 136
INS  A 301 (-2.7A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
MG  A 303 ( 2.9A)
0.92A 1ekjG-4xf7A:
undetectable
1ekjH-4xf7A:
undetectable
1ekjG-4xf7A:
23.49
1ekjH-4xf7A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 8 PHE A 180
GLY A 159
LEU A 125
PHE A 176
None
0.99A 1gsfC-4xf7A:
undetectable
1gsfC-4xf7A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 9 GLY A   7
THR A  45
ILE A  96
THR A  73
SER A  69
None
1.42A 1gtnR-4xf7A:
undetectable
1gtnS-4xf7A:
undetectable
1gtnR-4xf7A:
15.20
1gtnS-4xf7A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A  73
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
None
INS  A 301 (-2.7A)
1.16A 1likA-4xf7A:
22.9
1likA-4xf7A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 11 GLY A 223
PHE A 248
GLY A 218
GLY A  27
GLY A  26
None
None
ACP  A 302 (-3.2A)
INS  A 301 (-3.8A)
INS  A 301 (-3.1A)
1.01A 1mxgA-4xf7A:
undetectable
1mxgA-4xf7A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
3 / 3 ASP A  12
THR A  73
GLU A 115
INS  A 301 (-2.8A)
None
None
0.84A 1pj7A-4xf7A:
5.3
1pj7A-4xf7A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
GLY A 216
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
ACP  A 302 (-3.9A)
INS  A 301 (-2.7A)
0.70A 2pkkA-4xf7A:
26.9
2pkkA-4xf7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
GLY A 216
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
ACP  A 302 (-3.9A)
INS  A 301 (-2.7A)
0.71A 2pkmA-4xf7A:
27.0
2pkmA-4xf7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 5 ILE A 147
TYR A  75
ARG A  92
GLY A 137
None
INS  A 301 (-3.8A)
None
None
1.25A 3b9mA-4xf7A:
undetectable
3b9mA-4xf7A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 8 ILE A 152
PRO A 111
ASN A 110
VAL A 121
None
0.95A 3em0B-4xf7A:
undetectable
3em0B-4xf7A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 8 ALA A 265
PHE A  38
PHE A 244
ALA A 241
IOD  A 307 ( 4.6A)
None
None
None
0.91A 3t3sF-4xf7A:
undetectable
3t3sF-4xf7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.81A 3uboB-4xf7A:
24.4
3uboB-4xf7A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 7 GLU A 169
ILE A 139
HIS A   8
VAL A   5
MG  A 303 ( 4.0A)
None
None
None
1.11A 4a97H-4xf7A:
undetectable
4a97H-4xf7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
6 / 12 ASP A  12
GLY A  25
GLY A  26
LEU A  89
GLY A 216
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
None
ACP  A 302 (-3.9A)
INS  A 301 (-2.7A)
1.25A 4dc3B-4xf7A:
22.9
4dc3B-4xf7A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A  73
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
None
INS  A 301 (-2.7A)
1.09A 4e3aA-4xf7A:
24.5
4e3aA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.74A 4e3aA-4xf7A:
24.5
4e3aA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
6 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
GLY A 216
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
ACP  A 302 (-3.9A)
INS  A 301 (-2.7A)
0.71A 4e3aB-4xf7A:
24.4
4e3aB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 11 GLN A 236
ALA A 237
ALA A 241
THR A 245
LEU A  35
IOD  A 307 ( 4.7A)
None
None
ACP  A 302 (-3.8A)
None
0.84A 4j6cA-4xf7A:
undetectable
4j6cA-4xf7A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 10 GLN A 236
ALA A 237
ALA A 241
THR A 245
LEU A  35
IOD  A 307 ( 4.7A)
None
None
ACP  A 302 (-3.8A)
None
0.85A 4j6cB-4xf7A:
undetectable
4j6cB-4xf7A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 GLN A 236
ALA A 237
ALA A 241
THR A 245
LEU A  35
IOD  A 307 ( 4.7A)
None
None
ACP  A 302 (-3.8A)
None
0.86A 4jbtA-4xf7A:
undetectable
4jbtA-4xf7A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.81A 4jksA-4xf7A:
24.5
4jksA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4jksB-4xf7A:
24.5
4jksB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.81A 4jkuA-4xf7A:
21.7
4jkuA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.81A 4jkuB-4xf7A:
24.5
4jkuB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.83A 4k8cA-4xf7A:
21.7
4k8cA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4k8cB-4xf7A:
24.5
4k8cB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4k8kA-4xf7A:
24.5
4k8kA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4k8kB-4xf7A:
24.5
4k8kB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4k8pA-4xf7A:
24.4
4k8pA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4k8pB-4xf7A:
24.3
4k8pB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4k8tA-4xf7A:
24.4
4k8tA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4k8tB-4xf7A:
24.4
4k8tB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4k93A-4xf7A:
24.5
4k93A-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.81A 4k93B-4xf7A:
24.5
4k93B-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4k9cA-4xf7A:
24.6
4k9cA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.79A 4k9cB-4xf7A:
24.5
4k9cB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.81A 4k9iA-4xf7A:
24.5
4k9iA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4k9iB-4xf7A:
24.5
4k9iB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4kadA-4xf7A:
24.4
4kadA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.83A 4kadB-4xf7A:
21.6
4kadB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.81A 4kahA-4xf7A:
21.7
4kahA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4kahB-4xf7A:
24.5
4kahB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4kalA-4xf7A:
24.5
4kalA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4kalB-4xf7A:
24.4
4kalB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4kanA-4xf7A:
21.7
4kanA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.79A 4kanB-4xf7A:
24.4
4kanB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.83A 4kbeA-4xf7A:
21.8
4kbeA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4kbeB-4xf7A:
21.6
4kbeB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4lbgA-4xf7A:
24.5
4lbgA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4lbgB-4xf7A:
24.6
4lbgB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4lbxA-4xf7A:
24.5
4lbxA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.81A 4lbxB-4xf7A:
24.6
4lbxB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4lc4A-4xf7A:
24.5
4lc4A-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.82A 4lc4B-4xf7A:
24.4
4lc4B-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.80A 4lcaA-4xf7A:
24.5
4lcaA-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 ASP A  12
GLY A  25
GLY A  26
THR A 215
ASP A 219
INS  A 301 (-2.8A)
INS  A 301 (-3.1A)
INS  A 301 (-3.1A)
INS  A 301 (-4.7A)
INS  A 301 (-2.7A)
0.81A 4lcaB-4xf7A:
24.4
4lcaB-4xf7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
3 / 3 ARG A 140
ASP A 134
ARG A  85
INS  A 301 (-2.7A)
MG  A 303 ( 4.0A)
ACP  A 302 (-2.9A)
0.98A 4mx0A-4xf7A:
undetectable
4mx0A-4xf7A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 9 THR A  73
SER A  69
GLY A   7
THR A  45
ILE A  96
None
1.39A 5eezB-4xf7A:
undetectable
5eezC-4xf7A:
undetectable
5eezB-4xf7A:
15.20
5eezC-4xf7A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 9 THR A  73
SER A  69
GLY A   7
THR A  45
ILE A  96
None
1.39A 5ef0B-4xf7A:
undetectable
5ef0C-4xf7A:
undetectable
5ef0B-4xf7A:
15.20
5ef0C-4xf7A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 9 THR A  73
SER A  69
GLY A   7
THR A  45
ILE A  96
None
1.39A 5ef1B-4xf7A:
undetectable
5ef1C-4xf7A:
undetectable
5ef1B-4xf7A:
15.20
5ef1C-4xf7A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 9 THR A  73
SER A  69
GLY A   7
THR A  45
ILE A  96
None
1.39A 5ef2B-4xf7A:
undetectable
5ef2C-4xf7A:
undetectable
5ef2B-4xf7A:
15.20
5ef2C-4xf7A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 9 THR A  73
SER A  69
GLY A   7
THR A  45
ILE A  96
None
1.39A 5ef3B-4xf7A:
undetectable
5ef3C-4xf7A:
undetectable
5ef3B-4xf7A:
15.20
5ef3C-4xf7A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 VAL A 261
LEU A 108
VAL A 220
GLY A 223
ALA A 224
None
1.10A 5iktA-4xf7A:
undetectable
5iktA-4xf7A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
5 / 12 LEU A  77
ASP A 219
GLY A 216
VAL A  10
LYS A  16
INS  A 301 ( 4.8A)
INS  A 301 (-2.7A)
ACP  A 302 (-3.9A)
INS  A 301 ( 4.8A)
None
1.33A 5kbwB-4xf7A:
undetectable
5kbwB-4xf7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 7 GLY A   7
GLU A 115
ALA A 113
ASP A 134
None
None
None
MG  A 303 ( 4.0A)
0.97A 5mvsA-4xf7A:
2.7
5mvsA-4xf7A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 8 GLY A   7
GLU A 115
ALA A 113
ASP A 134
None
None
None
MG  A 303 ( 4.0A)
0.97A 5mvsB-4xf7A:
2.7
5mvsB-4xf7A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 4 GLY A 227
ALA A 224
MET A 258
THR A 245
None
None
None
ACP  A 302 (-3.8A)
1.49A 5n0sB-4xf7A:
undetectable
5n0sB-4xf7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis)
4 / 7 TYR A  30
TYR A  29
GLN A 136
ASP A 134
INS  A 301 (-4.6A)
None
MG  A 303 ( 2.9A)
MG  A 303 ( 4.0A)
1.29A 5ov9B-4xf7A:
undetectable
5ov9B-4xf7A:
19.34