SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xfw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 7 HIS A 110
HIS A 112
HIS A 129
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
 0.35A 1am6A-4xfwA:
26.4		 1am6A-4xfwA:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 8 HIS A 110
HIS A 112
HIS A 129
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
 0.49A 1azmA-4xfwA:
25.6		 1azmA-4xfwA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 8 HIS A 110
HIS A 112
HIS A 129
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
 0.44A 1bzmA-4xfwA:
25.6		 1bzmA-4xfwA:
29.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A  84
HIS A 110
HIS A 112
HIS A 129
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.95A 1cilA-4xfwA:
26.5		 1cilA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A  84
HIS A 110
HIS A 129
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
 1.48A 1cilA-4xfwA:
26.5		 1cilA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A  85
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.79A 1cilA-4xfwA:
26.5		 1cilA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.45A 1cilA-4xfwA:
26.5		 1cilA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 11 HIS A 110
HIS A 112
HIS A 129
LEU A 139
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.83A 1dmyA-4xfwA:
23.3		 1dmyA-4xfwA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 11 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.59A 1dmyA-4xfwA:
23.3		 1dmyA-4xfwA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.57A 1dmyB-4xfwA:
23.2		 1dmyB-4xfwA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.13A 1dmyB-4xfwA:
23.2		 1dmyB-4xfwA:
30.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.40A 1jd0A-4xfwA:
26.2		 1jd0A-4xfwA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.43A 1jd0B-4xfwA:
26.1		 1jd0B-4xfwA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.11A 1jd0B-4xfwA:
26.1		 1jd0B-4xfwA:
29.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 ASN A 108
HIS A 112
VAL A 141
THR A 191
PRO A 194
 None
ZN  A 301 (-3.4A)
None
ZN  A 301 (-4.3A)
None
 0.87A 1oq5A-4xfwA:
26.8		 1oq5A-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A 110
HIS A 112
VAL A 131
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.46A 1oq5A-4xfwA:
26.8		 1oq5A-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 112
VAL A 141
LEU A 190
THR A 191
PRO A 194
 ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 0.88A 1oq5A-4xfwA:
26.8		 1oq5A-4xfwA:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.46A 1rj6A-4xfwA:
26.1		 1rj6A-4xfwA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.47A 1rj6B-4xfwA:
26.0		 1rj6B-4xfwA:
28.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 110
HIS A 129
VAL A 131
VAL A 141
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.41A 1ydaA-4xfwA:
26.2		 1ydaA-4xfwA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 11 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.31A 1ydbA-4xfwA:
26.5		 1ydbA-4xfwA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
THR A 191
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 0.27A 1yddA-4xfwA:
26.6		 1yddA-4xfwA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
HIS A 112
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 0.60A 1z9yA-4xfwA:
26.7		 1z9yA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
HIS A 112
VAL A 131
VAL A 141
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 0.31A 1z9yA-4xfwA:
26.7		 1z9yA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 ASN A 108
HIS A 110
HIS A 112
HIS A 129
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
 1.10A 1zgfA-4xfwA:
26.7		 1zgfA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.52A 1zgfA-4xfwA:
26.7		 1zgfA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 12 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.44A 1zsbA-4xfwA:
26.6		 1zsbA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.21A 1zsbA-4xfwA:
26.6		 1zsbA-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
VAL A 131
LEU A 139
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
None
ZN  A 301 (-4.3A)
None
 0.46A 2aw1A-4xfwA:
26.7		 2aw1A-4xfwA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 8 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.31A 2gehA-4xfwA:
26.7		 2gehA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 9 HIS A 112
HIS A 129
VAL A 131
THR A 191
TRP A 201
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
 0.33A 2h4nA-4xfwA:
26.6		 2h4nA-4xfwA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 8 HIS A 110
HIS A 112
HIS A 129
VAL A 141
LEU A 190
THR A 191
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 0.40A 2it4A-4xfwA:
25.7		 2it4A-4xfwA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 8 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.15A 2it4A-4xfwA:
25.7		 2it4A-4xfwA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 ASN A 108
HIS A 110
HIS A 112
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
ZN  A 301 (-4.3A)
None
 1.14A 2pouA-4xfwA:
26.6		 2pouA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A 110
HIS A 112
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.52A 2pouA-4xfwA:
26.6		 2pouA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.43A 3bl1A-4xfwA:
26.7		 3bl1A-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.21A 3bl1A-4xfwA:
26.7		 3bl1A-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.39A 3cajA-4xfwA:
26.6		 3cajA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 10 HIS A 112
VAL A 141
LEU A 190
THR A 191
PRO A 194
 ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 0.88A 3cajA-4xfwA:
26.6		 3cajA-4xfwA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.42A 3czvA-4xfwA:
26.6
3czvB-4xfwA:
26.7		 3czvA-4xfwA:
28.57
3czvB-4xfwA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.41A 3czvB-4xfwA:
26.7		 3czvB-4xfwA:
28.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.41A 3dazA-4xfwA:
26.5		 3dazA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 12 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.46A 3dc3A-4xfwA:
26.6		 3dc3A-4xfwA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.09A 3dc3A-4xfwA:
26.6		 3dc3A-4xfwA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.40A 3dcsA-4xfwA:
26.6		 3dcsA-4xfwA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.44A 3dcwA-4xfwA:
26.7		 3dcwA-4xfwA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 110
VAL A 131
VAL A 141
THR A 191
PRO A 193
TRP A 201
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
None
None
 1.24A 3dcwA-4xfwA:
26.7		 3dcwA-4xfwA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 10 HIS A 112
VAL A 131
LEU A 190
THR A 191
PRO A 194
 ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 1.16A 3dcwA-4xfwA:
26.7		 3dcwA-4xfwA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.45A 3dd0A-4xfwA:
26.5		 3dd0A-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 110
VAL A 131
VAL A 141
THR A 191
PRO A 193
TRP A 201
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
None
None
 1.26A 3dd0A-4xfwA:
26.5		 3dd0A-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 10 HIS A 112
VAL A 131
LEU A 190
THR A 191
PRO A 194
 ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 1.16A 3dd0A-4xfwA:
26.5		 3dd0A-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 ASN A 108
HIS A 110
HIS A 112
LEU A 190
THR A 191
PRO A 194
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
ZN  A 301 (-4.3A)
None
 0.93A 3f4xA-4xfwA:
26.4		 3f4xA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 ASN A 108
HIS A 112
VAL A 141
LEU A 190
THR A 191
PRO A 194
 None
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 0.83A 3f4xA-4xfwA:
26.4		 3f4xA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
VAL A 131
VAL A 141
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.48A 3f4xA-4xfwA:
26.4		 3f4xA-4xfwA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A  84
HIS A 110
HIS A 112
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
ZN  A 301 (-4.3A)
None
 1.00A 3fw3A-4xfwA:
25.5		 3fw3A-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A  85
HIS A 110
HIS A 112
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.3A)
None
 0.95A 3fw3A-4xfwA:
25.5		 3fw3A-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.40A 3fw3B-4xfwA:
25.4		 3fw3B-4xfwA:
28.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
HIS A 112
VAL A 131
VAL A 141
LEU A 190
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
None
 0.49A 3hkuA-4xfwA:
26.4		 3hkuA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		3 / 3 GLU A 116
HIS A 129
THR A 191
 ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
ZN  A 301 (-4.3A)
 0.36A 3hkuA-4xfwA:
26.4		 3hkuA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.45A 3hs4A-4xfwA:
26.6		 3hs4A-4xfwA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.43A 3iaiA-4xfwA:
25.6		 3iaiA-4xfwA:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.44A 3iaiB-4xfwA:
25.9		 3iaiB-4xfwA:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.41A 3iaiC-4xfwA:
25.9		 3iaiC-4xfwA:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.43A 3iaiD-4xfwA:
25.8		 3iaiD-4xfwA:
27.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.51A 3kwaA-4xfwA:
26.4		 3kwaA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 11 HIS A 110
VAL A 131
VAL A 141
LEU A 190
THR A 191
PRO A 193
TRP A 201
 ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 1.35A 3kwaA-4xfwA:
26.4		 3kwaA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 11 HIS A 112
HIS A 129
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
None
 1.49A 3kwaA-4xfwA:
26.4		 3kwaA-4xfwA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A  84
HIS A 112
VAL A 131
LEU A 190
THR A 191
 None
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
 1.00A 3lxeA-4xfwA:
25.8		 3lxeA-4xfwA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
HIS A 112
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 0.46A 3lxeA-4xfwA:
25.8		 3lxeA-4xfwA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A  84
HIS A 112
VAL A 131
LEU A 190
THR A 191
 None
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
 0.98A 3lxeB-4xfwA:
25.8		 3lxeB-4xfwA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
HIS A 112
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 0.44A 3lxeB-4xfwA:
25.8		 3lxeB-4xfwA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.50A 3mdzA-4xfwA:
26.1		 3mdzA-4xfwA:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 11 HIS A 112
GLU A 116
VAL A 141
LEU A 190
THR A 191
PRO A 194
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
None
 0.86A 3mdzA-4xfwA:
26.1		 3mdzA-4xfwA:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 11 HIS A 112
HIS A 129
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
None
 1.47A 3mdzA-4xfwA:
26.1		 3mdzA-4xfwA:
26.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.32A 3ml5A-4xfwA:
26.4		 3ml5A-4xfwA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.14A 3ml5A-4xfwA:
26.4		 3ml5A-4xfwA:
27.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.44A 3v2jA-4xfwA:
26.6		 3v2jA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.42A 3v2mA-4xfwA:
26.6		 3v2mA-4xfwA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 8 HIS A 110
HIS A 112
HIS A 129
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
 0.42A 3w6hA-4xfwA:
25.6		 3w6hA-4xfwA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 9 HIS A 110
HIS A 112
GLU A 116
HIS A 129
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
 0.43A 3w6hB-4xfwA:
25.6		 3w6hB-4xfwA:
29.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.53A 3zncA-4xfwA:
24.9		 3zncA-4xfwA:
30.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.36A 4coqA-4xfwA:
30.8		 4coqA-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.37A 4coqB-4xfwA:
30.8		 4coqB-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 VAL A 131
LEU A 139
LEU A 190
THR A 191
VAL A 199
TRP A 201
 None
None
None
ZN  A 301 (-4.3A)
None
None
 0.70A 4e3hA-4xfwA:
26.6		 4e3hA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 VAL A 131
LEU A 139
VAL A 141
THR A 191
VAL A 199
TRP A 201
 None
None
None
ZN  A 301 (-4.3A)
None
None
 0.44A 4e3hA-4xfwA:
26.6		 4e3hA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.45A 4g0cA-4xfwA:
26.5		 4g0cA-4xfwA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.38A 4g7aA-4xfwA:
30.4		 4g7aA-4xfwA:
35.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.37A 4g7aB-4xfwA:
30.2		 4g7aB-4xfwA:
35.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.44A 4k0sA-4xfwA:
26.7		 4k0sA-4xfwA:
32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.18A 4k0sA-4xfwA:
26.7		 4k0sA-4xfwA:
32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.37A 4k0zA-4xfwA:
26.6		 4k0zA-4xfwA:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 139
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
None
ZN  A 301 (-4.3A)
None
 0.54A 4k13A-4xfwA:
26.7		 4k13A-4xfwA:
32.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.53A 4lu3A-4xfwA:
26.1		 4lu3A-4xfwA:
27.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
VAL A 131
VAL A 141
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.51A 4m2rA-4xfwA:
26.6		 4m2rA-4xfwA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
VAL A 131
VAL A 141
THR A 191
PRO A 193
TRP A 201
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
None
None
 1.23A 4m2rA-4xfwA:
26.6		 4m2rA-4xfwA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A  84
HIS A 110
HIS A 112
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 1.03A 4m2uA-4xfwA:
26.5		 4m2uA-4xfwA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A  85
HIS A 110
HIS A 112
VAL A 131
VAL A 141
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 0.82A 4m2uA-4xfwA:
26.5		 4m2uA-4xfwA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 TRP A  23
HIS A 110
HIS A 112
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.51A 4m2uA-4xfwA:
26.5		 4m2uA-4xfwA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 TRP A  35
HIS A 110
HIS A 112
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
ZN  A 301 (-4.3A)
None
 1.23A 4m2uA-4xfwA:
26.5		 4m2uA-4xfwA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
HIS A 112
VAL A 131
GLY A 137
LEU A 190
THR A 191
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
ZN  A 301 (-4.3A)
 1.34A 4m2vA-4xfwA:
26.7		 4m2vA-4xfwA:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A 110
HIS A 112
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.45A 4m2vA-4xfwA:
26.7		 4m2vA-4xfwA:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 139
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
None
ZN  A 301 (-4.3A)
None
 0.59A 4m2wA-4xfwA:
26.6		 4m2wA-4xfwA:
32.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 5 TYR A 183
THR A 196
LEU A 190
MET A 115
 None
None
None
CL  A 302 (-4.6A)
 1.41A 4mbsB-4xfwA:
undetectable		 4mbsB-4xfwA:
19.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 8 HIS A 110
HIS A 112
HIS A 129
THR A 191
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
ZN  A 301 (-4.3A)
 0.19A 4n16A-4xfwA:
26.6		 4n16A-4xfwA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 ILE A 181
ASN A 154
ASN A 152
LEU A 208
GLY A 145
 None
 1.21A 4r38C-4xfwA:
undetectable		 4r38C-4xfwA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 112
VAL A 131
VAL A 141
THR A 191
ALA A 192
TRP A 201
 ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.45A 4twlA-4xfwA:
29.1		 4twlA-4xfwA:
29.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 112
VAL A 131
VAL A 141
THR A 191
ALA A 192
TRP A 201
 ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.42A 4twlB-4xfwA:
29.2		 4twlB-4xfwA:
29.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.35A 4uovA-4xfwA:
30.5		 4uovA-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.00A 4uovA-4xfwA:
30.5		 4uovA-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.36A 4uovB-4xfwA:
30.5		 4uovB-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.03A 4uovB-4xfwA:
30.5		 4uovB-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.36A 4uovC-4xfwA:
30.5		 4uovC-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 0.99A 4uovC-4xfwA:
30.5		 4uovC-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.36A 4uovD-4xfwA:
30.5		 4uovD-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.00A 4uovD-4xfwA:
30.5		 4uovD-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.34A 4uovE-4xfwA:
30.4		 4uovE-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.01A 4uovE-4xfwA:
30.4		 4uovE-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.34A 4uovF-4xfwA:
30.6		 4uovF-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.00A 4uovF-4xfwA:
30.6		 4uovF-4xfwA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.41A 4x5sA-4xfwA:
30.8		 4x5sA-4xfwA:
37.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.41A 4x5sB-4xfwA:
30.8		 4x5sB-4xfwA:
37.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 ILE A 239
VAL A 203
ASN A 121
ILE A  54
ASP A 234
 None
 1.44A 4xe0A-4xfwA:
undetectable		 4xe0A-4xfwA:
11.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 12 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.41A 4xiwA-4xfwA:
25.9
4xiwH-4xfwA:
25.6		 4xiwA-4xfwA:
33.33
4xiwH-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.47A 4xiwB-4xfwA:
26.0
4xiwE-4xfwA:
25.8		 4xiwB-4xfwA:
33.33
4xiwE-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.51A 4xiwC-4xfwA:
25.8		 4xiwC-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 141
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 0.81A 4xiwC-4xfwA:
25.8		 4xiwC-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.40A 4xiwD-4xfwA:
25.9		 4xiwD-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.38A 4xiwE-4xfwA:
25.8		 4xiwE-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.42A 4xiwF-4xfwA:
25.5		 4xiwF-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.07A 4xiwF-4xfwA:
25.5		 4xiwF-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 12 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 139
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
None
ZN  A 301 (-4.3A)
None
 0.63A 4xiwG-4xfwA:
25.5		 4xiwG-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 112
GLU A 116
LEU A 139
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
None
ZN  A 301 (-4.3A)
 1.50A 4xiwG-4xfwA:
25.5		 4xiwG-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.47A 4xiwH-4xfwA:
25.6		 4xiwH-4xfwA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 11 ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.33A 4ygfA-4xfwA:
38.5		 4ygfA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
HIS A 110
VAL A 131
LEU A 190
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
None
None
 1.45A 4ygfA-4xfwA:
38.5		 4ygfA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 11 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 1.09A 4ygfA-4xfwA:
38.5		 4ygfA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.42A 4ygfA-4xfwA:
38.5		 4ygfA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 LYS A  88
ASN A 108
HIS A 110
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.57A 4ygfA-4xfwA:
38.5		 4ygfA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 11 ASN A 108
HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.39A 4ygfB-4xfwA:
38.2		 4ygfB-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 11 HIS A 110
HIS A 129
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 1.43A 4ygfB-4xfwA:
38.2		 4ygfB-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 11 HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.04A 4ygfB-4xfwA:
38.2		 4ygfB-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 11 HIS A 129
LYS A 133
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.85A 4ygfB-4xfwA:
38.2		 4ygfB-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 11 ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.30A 4ygfC-4xfwA:
38.9		 4ygfC-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
HIS A 110
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
 1.43A 4ygfC-4xfwA:
38.9		 4ygfC-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 11 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 1.12A 4ygfC-4xfwA:
38.9		 4ygfC-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.34A 4ygfC-4xfwA:
38.9		 4ygfC-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 11 LYS A  88
ASN A 108
HIS A 110
HIS A 129
VAL A 131
VAL A 141
LEU A 190
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
None
None
 0.62A 4ygfC-4xfwA:
38.9		 4ygfC-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		11 / 11 ASN A 108
HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.43A 4ygfD-4xfwA:
37.6		 4ygfD-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 11 HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 1.13A 4ygfD-4xfwA:
37.6		 4ygfD-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.36A 4ygfD-4xfwA:
37.6		 4ygfD-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 GLU A 116
HIS A 129
LYS A 133
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.80A 4ygfE-4xfwA:
39.1		 4ygfE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
HIS A 129
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 1.44A 4ygfE-4xfwA:
39.1		 4ygfE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 110
LYS A 133
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.3A)
 1.20A 4ygfE-4xfwA:
39.1		 4ygfE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.00A 4ygfE-4xfwA:
39.1		 4ygfE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 112
HIS A 110
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
 1.45A 4ygfE-4xfwA:
39.1		 4ygfE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		11 / 12 LYS A  88
ASN A 108
HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.37A 4ygfE-4xfwA:
39.1		 4ygfE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 9 ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.40A 4ygfF-4xfwA:
38.5		 4ygfF-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 9 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.13A 4ygfF-4xfwA:
38.5		 4ygfF-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 110
LYS A 133
VAL A 131
THR A 191
ALA A 192
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
None
 1.42A 4ygfG-4xfwA:
38.5		 4ygfG-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 112
HIS A 110
VAL A 131
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.3A)
None
 1.46A 4ygfG-4xfwA:
38.5		 4ygfG-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 1.11A 4ygfG-4xfwA:
38.5		 4ygfG-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.41A 4ygfG-4xfwA:
38.5		 4ygfG-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A 129
LYS A 133
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.89A 4ygfG-4xfwA:
38.5		 4ygfG-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		11 / 12 LYS A  88
ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.46A 4ygfG-4xfwA:
38.5		 4ygfG-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 9 ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.32A 4ygfH-4xfwA:
38.6		 4ygfH-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 9 HIS A 112
HIS A 110
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
 1.41A 4ygfH-4xfwA:
38.6		 4ygfH-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 9 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.10A 4ygfH-4xfwA:
38.6		 4ygfH-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		11 / 12 ASP A 107
ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.32A 4yhaA-4xfwA:
38.1		 4yhaA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 1.16A 4yhaA-4xfwA:
38.1		 4yhaA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 112
HIS A 110
VAL A 131
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
None
 1.42A 4yhaA-4xfwA:
38.1		 4yhaA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.37A 4yhaA-4xfwA:
38.1		 4yhaA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 LYS A  88
ASP A 107
ASN A 108
HIS A 129
VAL A 131
VAL A 141
LEU A 190
TRP A 201
 None
None
None
ZN  A 301 ( 3.1A)
None
None
None
None
 0.67A 4yhaA-4xfwA:
38.1		 4yhaA-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 10 ASP A 107
ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.51A 4yhaB-4xfwA:
36.8		 4yhaB-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 1.14A 4yhaB-4xfwA:
36.8		 4yhaB-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 11 ASP A 107
ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.26A 4yhaC-4xfwA:
38.9		 4yhaC-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.05A 4yhaC-4xfwA:
38.9		 4yhaC-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 LYS A  88
ASP A 107
ASN A 108
HIS A 110
HIS A 129
VAL A 131
VAL A 141
LEU A 190
TRP A 201
 None
None
None
ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
None
None
 0.58A 4yhaC-4xfwA:
38.9		 4yhaC-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 11 HIS A 110
HIS A 129
LEU A 190
THR A 191
ALA A 192
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
None
 1.45A 4yhaD-4xfwA:
36.7		 4yhaD-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
None
 0.97A 4yhaD-4xfwA:
36.7		 4yhaD-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.42A 4yhaD-4xfwA:
36.7		 4yhaD-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		11 / 11 LYS A  88
ASN A 108
HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.46A 4yhaD-4xfwA:
36.7		 4yhaD-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A 110
HIS A 129
LEU A 190
THR A 191
ALA A 192
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
ZN  A 301 (-4.3A)
None
None
None
 1.45A 4yhaE-4xfwA:
38.7		 4yhaE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
PRO A 194
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
None
 1.11A 4yhaE-4xfwA:
38.7		 4yhaE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
PRO A 194
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
None
 1.31A 4yhaE-4xfwA:
38.7		 4yhaE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		12 / 12 LYS A  88
ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
PRO A 194
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
None
 0.35A 4yhaE-4xfwA:
38.7		 4yhaE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 LYS A  88
ASN A 108
HIS A 110
LEU A 190
THR A 191
PRO A 193
TRP A 201
 None
None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.3A)
None
None
 1.34A 4yhaE-4xfwA:
38.7		 4yhaE-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 10 ASP A 107
ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.61A 4yhaF-4xfwA:
33.8		 4yhaF-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 10 HIS A 112
VAL A 141
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 1.12A 4yhaF-4xfwA:
33.8		 4yhaF-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 12 HIS A 112
HIS A 129
VAL A 131
LYS A 133
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.65A 4yhaG-4xfwA:
37.8		 4yhaG-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.39A 4yhaG-4xfwA:
37.8		 4yhaG-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		11 / 12 LYS A  88
ASN A 108
HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.40A 4yhaG-4xfwA:
37.8		 4yhaG-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 10 ASN A 108
HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.35A 4yhaH-4xfwA:
38.3		 4yhaH-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 10 ASN A 108
HIS A 110
HIS A 112
LEU A 190
THR A 191
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
ZN  A 301 (-4.3A)
 1.40A 4yhaH-4xfwA:
38.3		 4yhaH-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 10 HIS A 112
GLU A 116
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
None
 1.09A 4yhaH-4xfwA:
38.3		 4yhaH-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 10 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.37A 4yhaH-4xfwA:
38.3		 4yhaH-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 12 HIS A 110
HIS A 112
GLU A 116
VAL A 131
VAL A 141
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.44A 5c8iA-4xfwA:
26.5		 5c8iA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
VAL A 131
VAL A 141
THR A 191
PRO A 193
TRP A 201
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
None
None
 1.27A 5c8iA-4xfwA:
26.5		 5c8iA-4xfwA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
PRO A 194
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
None
 1.16A 5c8iA-4xfwA:
26.5		 5c8iA-4xfwA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 7 ILE A 119
ILE A 144
ILE A 181
LEU A 208
 None
 0.81A 5fukA-4xfwA:
undetectable
5fukB-4xfwA:
undetectable		 5fukA-4xfwA:
23.32
5fukB-4xfwA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 7 LEU A 142
VAL A 131
ILE A 158
VAL A 109
 None
 0.93A 5jh7C-4xfwA:
undetectable		 5jh7C-4xfwA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.35A 5jn8A-4xfwA:
25.0		 5jn8A-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.35A 5jn8B-4xfwA:
25.3		 5jn8B-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.00A 5jn8B-4xfwA:
25.3		 5jn8B-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.29A 5jn8C-4xfwA:
24.9		 5jn8C-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.33A 5jn8D-4xfwA:
24.8		 5jn8D-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.38A 5jn9A-4xfwA:
25.1		 5jn9A-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.38A 5jn9B-4xfwA:
25.5		 5jn9B-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.33A 5jn9C-4xfwA:
24.9		 5jn9C-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.39A 5jn9D-4xfwA:
24.8		 5jn9D-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
 0.40A 5jnaA-4xfwA:
25.0		 5jnaA-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.02A 5jnaA-4xfwA:
25.0		 5jnaA-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.38A 5jnaB-4xfwA:
25.3		 5jnaB-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 11 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
 0.37A 5jnaC-4xfwA:
24.8		 5jnaC-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.42A 5jnaD-4xfwA:
24.7		 5jnaD-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 11 HIS A 110
HIS A 112
GLU A 116
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.39A 5jncA-4xfwA:
25.1		 5jncA-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 11 HIS A 112
GLU A 116
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-4.9A)
None
None
ZN  A 301 (-4.3A)
 1.01A 5jncA-4xfwA:
25.1		 5jncA-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.38A 5jncB-4xfwA:
25.4		 5jncB-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.31A 5jncC-4xfwA:
24.9		 5jncC-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.31A 5jncD-4xfwA:
24.7		 5jncD-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.32A 5ku6A-4xfwA:
25.0		 5ku6A-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 10 HIS A 112
HIS A 110
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
 1.41A 5ku6A-4xfwA:
25.0		 5ku6A-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.35A 5ku6B-4xfwA:
25.4		 5ku6B-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 10 HIS A 112
HIS A 110
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
 1.41A 5ku6B-4xfwA:
25.4		 5ku6B-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.29A 5ku6C-4xfwA:
24.9		 5ku6C-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.29A 5ku6D-4xfwA:
24.7		 5ku6D-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 7 HIS A 110
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
 0.28A 5m78A-4xfwA:
26.6		 5m78A-4xfwA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 6 HIS A 110
HIS A 129
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.49A 5ogjA-4xfwA:
26.8		 5ogjA-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 6 HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.22A 5ogjA-4xfwA:
26.8		 5ogjA-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 6 HIS A 110
HIS A 129
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.48A 5ogjB-4xfwA:
26.3		 5ogjB-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 6 HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.21A 5ogjB-4xfwA:
26.3		 5ogjB-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 5 HIS A 110
HIS A 129
VAL A 141
LEU A 190
THR A 191
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 0.48A 5ohhA-4xfwA:
26.4		 5ohhA-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 5 HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.22A 5ohhA-4xfwA:
26.4		 5ohhA-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 6 HIS A 110
HIS A 129
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 0.48A 5ohhB-4xfwA:
26.8		 5ohhB-4xfwA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 6 HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 1.21A 5ohhB-4xfwA:
26.8		 5ohhB-4xfwA:
28.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
None
 0.35A 5tt3A-4xfwA:
37.9		 5tt3A-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 110
HIS A 129
VAL A 141
LEU A 190
ALA A 192
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
None
None
None
 1.47A 5tt3A-4xfwA:
37.9		 5tt3A-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
PRO A 194
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
None
 1.09A 5tt3A-4xfwA:
37.9		 5tt3A-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
PRO A 194
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
None
 1.42A 5tt3A-4xfwA:
37.9		 5tt3A-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.49A 5tt3B-4xfwA:
34.7		 5tt3B-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 9 HIS A 112
HIS A 110
VAL A 131
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.3A)
None
 1.29A 5tt3B-4xfwA:
34.7		 5tt3B-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 9 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
 1.15A 5tt3B-4xfwA:
34.7		 5tt3B-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		10 / 10 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
None
 0.37A 5tt3C-4xfwA:
38.6		 5tt3C-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 110
HIS A 129
VAL A 141
LEU A 190
ALA A 192
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
None
None
None
 1.44A 5tt3C-4xfwA:
38.6		 5tt3C-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 110
VAL A 131
VAL A 141
THR A 191
PRO A 193
TRP A 201
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
None
None
 1.31A 5tt3C-4xfwA:
38.6		 5tt3C-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 10 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
PRO A 194
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
None
 1.06A 5tt3C-4xfwA:
38.6		 5tt3C-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 10 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
PRO A 194
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
None
 1.37A 5tt3C-4xfwA:
38.6		 5tt3C-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.33A 5tt3E-4xfwA:
38.6		 5tt3E-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 9 HIS A 112
HIS A 110
VAL A 131
LEU A 190
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
None
None
 1.41A 5tt3E-4xfwA:
38.6		 5tt3E-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 9 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.47A 5tt3E-4xfwA:
38.6		 5tt3E-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 8 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
 0.39A 5tt3F-4xfwA:
37.1		 5tt3F-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 8 HIS A 110
HIS A 129
VAL A 141
LEU A 190
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 ( 3.1A)
None
None
None
 1.37A 5tt3F-4xfwA:
37.1		 5tt3F-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 8 HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
 0.97A 5tt3F-4xfwA:
37.1		 5tt3F-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		9 / 9 HIS A 110
HIS A 112
HIS A 129
VAL A 131
VAL A 141
LEU A 190
THR A 191
ALA A 192
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.31A 5tt3G-4xfwA:
36.8		 5tt3G-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 9 HIS A 112
HIS A 110
VAL A 131
LEU A 190
THR A 191
ALA A 192
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
None
 1.39A 5tt3G-4xfwA:
36.8		 5tt3G-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 9 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.37A 5tt3G-4xfwA:
36.8		 5tt3G-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 8 HIS A 110
HIS A 112
HIS A 129
VAL A 131
LEU A 190
THR A 191
ALA A 192
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.1A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.48A 5tt3H-4xfwA:
37.5		 5tt3H-4xfwA:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 8 HIS A 129
HIS A 112
VAL A 141
LEU A 190
ALA A 192
 ZN  A 301 ( 3.1A)
ZN  A 301 (-3.4A)
None
None
None
 1.43A 5tt3H-4xfwA:
37.5		 5tt3H-4xfwA:
99.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 LEU A 126
GLY A 145
VAL A 204
PHE A 111
GLN A 214
 None
 1.35A 5uc3B-4xfwA:
undetectable		 5uc3B-4xfwA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		3 / 3 GLU A 116
TRP A 201
HIS A 110
 ZN  A 301 (-4.9A)
None
ZN  A 301 (-3.3A)
 0.98A 5xipA-4xfwA:
undetectable		 5xipA-4xfwA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A  84
HIS A 110
HIS A 112
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
ZN  A 301 (-4.3A)
None
 1.06A 6bbsA-4xfwA:
22.0		 6bbsA-4xfwA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		5 / 12 HIS A  85
HIS A 110
HIS A 112
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 301 (-4.3A)
None
 0.74A 6bbsA-4xfwA:
22.0		 6bbsA-4xfwA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 TRP A  23
HIS A 110
HIS A 112
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
ZN  A 301 (-4.3A)
None
 0.64A 6bbsA-4xfwA:
22.0		 6bbsA-4xfwA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 TRP A  23
HIS A 110
HIS A 112
VAL A 131
LEU A 190
THR A 191
PRO A 194
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
None
 0.51A 6bc9A-4xfwA:
26.5		 6bc9A-4xfwA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		7 / 12 TRP A  35
HIS A 110
HIS A 112
VAL A 131
LEU A 190
THR A 191
TRP A 201
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
ZN  A 301 (-4.3A)
None
 1.28A 6bc9A-4xfwA:
26.5		 6bc9A-4xfwA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 5 GLU A 116
HIS A 129
LEU A 139
VAL A 141
 ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
None
 0.32A 6bc9A-4xfwA:
26.5		 6bc9A-4xfwA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 5 HIS A  84
GLU A 116
HIS A 129
VAL A 141
 None
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
 1.05A 6bc9A-4xfwA:
26.5		 6bc9A-4xfwA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		4 / 5 HIS A  85
GLU A 116
HIS A 129
VAL A 141
 None
ZN  A 301 (-4.9A)
ZN  A 301 ( 3.1A)
None
 0.79A 6bc9A-4xfwA:
26.5		 6bc9A-4xfwA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		8 / 12 HIS A 110
HIS A 112
VAL A 131
VAL A 141
LEU A 190
THR A 191
PRO A 194
TRP A 201
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
None
None
None
ZN  A 301 (-4.3A)
None
None
 0.45A 6bccA-4xfwA:
26.5		 6bccA-4xfwA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4xfw ALPHA-CARBONIC
ANHYDRASE
(Helicobacter
pylori) 		6 / 12 HIS A 110
VAL A 131
VAL A 141
THR A 191
PRO A 193
TRP A 201
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.3A)
None
None
 1.26A 6bccA-4xfwA:
26.5		 6bccA-4xfwA:
19.65