SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A 322
ALA A 321
LEU A 348
ALA A 347
ILE A 398
 None
 0.93A 1fm6U-4xg0A:
undetectable		 1fm6U-4xg0A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ALA A 321
VAL A 237
ALA A 295
ALA A 260
LEU A 298
 None
 1.06A 1jinA-4xg0A:
undetectable		 1jinA-4xg0A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 177
ALA A 178
LEU A 208
VAL A 115
LEU A 224
 None
 1.31A 1s9pB-4xg0A:
undetectable		 1s9pB-4xg0A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A 322
ALA A 321
LEU A 348
ALA A 347
ILE A 398
 None
 0.84A 2aclA-4xg0A:
undetectable
2aclE-4xg0A:
undetectable		 2aclA-4xg0A:
20.05
2aclE-4xg0A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 296
LEU A 324
GLY A 332
ALA A 331
ALA A 233
 None
 1.17A 2bm9C-4xg0A:
undetectable		 2bm9C-4xg0A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 296
LEU A 324
GLY A 332
ALA A 331
ALA A 233
 None
 1.16A 2bm9D-4xg0A:
undetectable		 2bm9D-4xg0A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 296
LEU A 324
GLY A 332
ALA A 331
ALA A 233
 None
 1.16A 2br4D-4xg0A:
undetectable		 2br4D-4xg0A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 296
LEU A 324
GLY A 332
ALA A 331
ALA A 233
 None
 1.14A 2br4E-4xg0A:
undetectable		 2br4E-4xg0A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 PHE A  23
THR A  19
LEU A 220
ALA A 222
 None
None
None
SO4  A 503 ( 3.7A)
 1.41A 2e1qD-4xg0A:
undetectable		 2e1qD-4xg0A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LYS A  88
LEU A  85
ILE A   6
PHE A  23
GLY A 209
 CIT  A 501 (-2.6A)
None
None
None
None
 1.30A 2lbdA-4xg0A:
undetectable		 2lbdA-4xg0A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 LEU A 326
LEU A 368
ALA A 373
ALA A 346
VAL A 344
 None
 1.29A 3e22B-4xg0A:
undetectable		 3e22B-4xg0A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 LEU A 326
LEU A 368
ALA A 373
ALA A 346
VAL A 344
 None
 1.28A 3e22D-4xg0A:
undetectable		 3e22D-4xg0A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 10 ALA A 322
ALA A 321
LEU A 348
ALA A 347
ILE A 398
 None
 0.80A 3falC-4xg0A:
undetectable		 3falC-4xg0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ALA A 322
ALA A 321
LEU A 348
ALA A 347
ILE A 398
 None
 0.86A 3fc6A-4xg0A:
undetectable		 3fc6A-4xg0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A 322
ALA A 321
LEU A 348
ALA A 347
ILE A 398
 None
 0.77A 3h0aA-4xg0A:
undetectable		 3h0aA-4xg0A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A 322
ALA A 321
LEU A 348
ALA A 347
ILE A 398
 None
 0.87A 3oapA-4xg0A:
undetectable		 3oapA-4xg0A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 GLY A 383
VAL A 241
SER A 243
THR A 336
 CL  A 502 ( 4.9A)
None
CL  A 502 ( 3.7A)
None
 1.03A 3tj7A-4xg0A:
undetectable
3tj7B-4xg0A:
undetectable		 3tj7A-4xg0A:
16.91
3tj7B-4xg0A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 VAL A 241
SER A 243
THR A 336
GLY A 383
 None
CL  A 502 ( 3.7A)
None
CL  A 502 ( 4.9A)
 1.02A 3tj7C-4xg0A:
undetectable
3tj7D-4xg0A:
undetectable		 3tj7C-4xg0A:
16.91
3tj7D-4xg0A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 THR A  56
SER A  58
LEU A  85
VAL A 213
VAL A  74
 None
 1.20A 3u9fB-4xg0A:
undetectable
3u9fC-4xg0A:
undetectable		 3u9fB-4xg0A:
18.86
3u9fC-4xg0A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 10 THR A  56
SER A  58
LEU A  85
VAL A 213
VAL A  74
 None
 1.25A 3u9fE-4xg0A:
undetectable		 3u9fE-4xg0A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 THR A  56
SER A  58
LEU A  85
VAL A 213
VAL A  74
 None
 1.23A 3u9fH-4xg0A:
undetectable
3u9fI-4xg0A:
undetectable		 3u9fH-4xg0A:
18.86
3u9fI-4xg0A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 THR A  56
SER A  58
LEU A  85
VAL A 213
VAL A  74
 None
 1.12A 3u9fJ-4xg0A:
undetectable
3u9fK-4xg0A:
undetectable		 3u9fJ-4xg0A:
18.86
3u9fK-4xg0A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 10 THR A  56
SER A  58
LEU A  85
VAL A 213
VAL A  74
 None
 1.18A 3u9fK-4xg0A:
undetectable		 3u9fK-4xg0A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 9 THR A  56
SER A  58
LEU A  85
VAL A 213
VAL A  74
 None
 1.23A 3u9fP-4xg0A:
undetectable		 3u9fP-4xg0A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A  93
GLY A 216
GLY A 219
PRO A 223
LEU A 224
 None
 1.30A 4x61A-4xg0A:
undetectable		 4x61A-4xg0A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 353
LEU A 348
VAL A 334
VAL A 333
LEU A 355
 None
 1.07A 5bykA-4xg0A:
undetectable		 5bykA-4xg0A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 353
LEU A 348
VAL A 334
VAL A 333
LEU A 355
 None
 1.09A 5tiwA-4xg0A:
4.7		 5tiwA-4xg0A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A 322
ALA A 321
LEU A 348
ALA A 347
ILE A 398
 None
 0.96A 6a5yD-4xg0A:
undetectable		 6a5yD-4xg0A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A 322
ALA A 321
LEU A 348
ALA A 347
ILE A 398
 None
 0.88A 6a5zL-4xg0A:
undetectable		 6a5zL-4xg0A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 353
LEU A 348
VAL A 334
VAL A 333
LEU A 355
 None
 1.03A 6b52A-4xg0A:
undetectable		 6b52A-4xg0A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 ALA A 119
THR A 126
GLN A 199
VAL A 198
 None
 0.93A 6cduA-4xg0A:
undetectable
6cduE-4xg0A:
undetectable		 6cduA-4xg0A:
19.09
6cduE-4xg0A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 GLN A 199
VAL A 198
ALA A 119
THR A 126
 None
 0.80A 6cduB-4xg0A:
undetectable
6cduC-4xg0A:
undetectable		 6cduB-4xg0A:
19.09
6cduC-4xg0A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 GLN A 199
VAL A 198
ALA A 119
THR A 126
 None
 0.84A 6cduC-4xg0A:
undetectable
6cduD-4xg0A:
undetectable		 6cduC-4xg0A:
19.09
6cduD-4xg0A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4xg0 UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 GLN A 199
VAL A 198
ALA A 119
THR A 126
 None
 0.94A 6cduH-4xg0A:
undetectable
6cduI-4xg0A:
undetectable		 6cduH-4xg0A:
19.09
6cduI-4xg0A:
19.09