SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xgc'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C8L_A_CFFA940_1 (PROTEIN (GLYCOGEN PHOSPHORYLASE))	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASN B 484 PHE B 351 GLY C 317 TYR C 320	None	1.05A	1c8lA-4xgcB: undetectable	1c8lA-4xgcB: 17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DVX_B_DIFB125_2 (TRANSTHYRETIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 7	LEU C 413 ALA C 466 LEU C 410 THR C 470	None	1.02A	1dvxB-4xgcC: undetectable	1dvxB-4xgcC: 12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EE2_A_CHDA1150_0 (ALCOHOL DEHYDROGENASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	5 / 11	SER D 168 LEU D 164 LEU D  84 LEU D 129 VAL D 177	None	1.19A	1ee2A-4xgcD: undetectable	1ee2A-4xgcD: 21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EE2_B_CHDB1250_1 (ALCOHOL DEHYDROGENASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	5 / 11	SER D 168 LEU D 164 LEU D  84 LEU D 129 VAL D 177	None	1.20A	1ee2B-4xgcD: undetectable	1ee2B-4xgcD: 21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IBG_H_OBNH1_2 (IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN) IGG2B-KAPPA 40-50 FAB (LIGHT CHAIN))	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 7	THR E 373 SER E 372 HIS E 337 LEU E 442	None	1.07A	1ibgL-4xgcE: undetectable	1ibgL-4xgcE: 17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IG3_B_VIBB501_1 (THIAMIN PYROPHOSPHOKINASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 7	GLN D 169 ASP D 166 LEU D 129 SER D  51	None	1.06A	1ig3A-4xgcD: undetectable 1ig3B-4xgcD: undetectable	1ig3A-4xgcD: 20.00 1ig3B-4xgcD: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ILQ_C_ACAC7_1 (INTERLEUKIN-8 PRECURSOR INTERLEUKIN-8 RECEPTOR A)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 6	HIS E 179 PHE E  40 ASP D 335 ASP D 334	None	1.42A	1ilqA-4xgcE: undetectable 1ilqC-4xgcE: undetectable	1ilqA-4xgcE: 10.61 1ilqC-4xgcE: 3.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KLM_A_SPPA999_1 (HIV-1 REVERSE TRANSCRIPTASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 11	LEU E 259 VAL E 221 TYR E 229 TYR E 226 LEU E 203	None	1.12A	1klmA-4xgcE: undetectable	1klmA-4xgcE: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5Q_B_CFFB1863_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASN B 484 PHE B 351 GLY C 317 TYR C 320	None	1.09A	1l5qB-4xgcB: undetectable	1l5qB-4xgcB: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_A_ACTA1869_0 (FPRA)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 4	ASP C 382 HIS C 350 ARG C 357 GLU C 354	None	1.42A	1lqtA-4xgcC: undetectable	1lqtA-4xgcC: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_A_ACTA1426_0 (FPRA)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 4	ASP C 382 HIS C 350 ARG C 357 GLU C 354	None	1.27A	1lquA-4xgcC: undetectable	1lquA-4xgcC: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NP1_B_HSMB304_1 (NITROPHORIN 1)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	3 / 3	ASP A 899 LEU D 429 LEU A 900	None	0.49A	1np1B-4xgcA: undetectable	1np1B-4xgcA: 17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OG5_A_SWFA502_1 (CYTOCHROME P450 2C9)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	LEU C 240 ALA C  99 PHE C  82 LEU C 238 THR C 118	None	1.12A	1og5A-4xgcC: undetectable	1og5A-4xgcC: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OG5_A_SWFA502_1 (CYTOCHROME P450 2C9)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	PHE C 290 LEU C 593 PHE C 400 THR C 296 PHE C 596	None	1.23A	1og5A-4xgcC: undetectable	1og5A-4xgcC: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_G_FUAG708_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	5 / 11	PHE D 165 SER D 141 PHE D  79 LEU D  40 VAL D  36	None	1.35A	1q23G-4xgcD: undetectable	1q23G-4xgcD: 18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_B_ADNB1502_1 (CLASS B ACID PHOSPHATASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 (Drosophila melanogaster)	4 / 7	PHE C 362 LEU C 379 TYR F 225 LYS F 223	None	1.18A	1rmtB-4xgcC: undetectable	1rmtB-4xgcC: 14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TYR_A_9CRA131_1 (TRANSTHYRETIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	LEU C 413 ALA C 466 LEU C 410 THR C 470	None	1.04A	1tyrA-4xgcC: undetectable	1tyrA-4xgcC: 12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE3_A_SAMA302_0 (HYPOTHETICAL PROTEIN PH0226)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster; Drosophila melanogaster)	5 / 12	ALA C 138 SER C 134 ALA C 142 ARG C 180 HIS B 412	None	1.14A	1ve3A-4xgcC: 2.2	1ve3A-4xgcC: 16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X70_B_715B801_2 (DIPEPTIDYL PEPTIDASE IV)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	3 / 3	PHE E 389 TYR C 307 TYR C 306	None	1.06A	1x70B-4xgcE: undetectable	1x70B-4xgcE: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X8V_A_ESLA471_1 (CYTOCHROME P450 51)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 8	PHE C 318 PHE C 326 ALA C 289 HIS C 291	None	0.95A	1x8vA-4xgcC: undetectable	1x8vA-4xgcC: 21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_F_9CRF1600_1 (RETINOIC ACID RECEPTOR, BETA)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	6 / 12	PHE B 483 ALA B 455 ILE B 390 ARG C 135 LEU B 442 LEU B 432	None	1.09A	1xdkF-4xgcB: undetectable	1xdkF-4xgcB: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XVA_B_SAMB293_0 (GLYCINE N-METHYLTRANSFERASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster; Drosophila melanogaster)	5 / 12	TYR B 339 ALA C 600 ASP C 598 ILE B 332 TYR B 336	None	1.38A	1xvaB-4xgcB: 2.3	1xvaB-4xgcB: 24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CEO_A_T44A1395_1 (THYROXINE-BINDING GLOBULIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 11	ALA C 143 LEU C 240 LEU C 238 LEU C 223 LEU C 209	None	0.67A	2ceoA-4xgcC: undetectable	2ceoA-4xgcC: 22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_B_SC2B1294_1 (FICOLIN-2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	5 / 9	GLY D  59 SER D  60 SER D 297 ASP D 295 GLU A 833	None	1.08A	2j2pB-4xgcD: undetectable 2j2pC-4xgcD: undetectable	2j2pB-4xgcD: 20.27 2j2pC-4xgcD: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_F_SC2F1291_1 (FICOLIN-2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 6	SER D  60 SER D 297 ASP D 295 GLU A 833	None	0.99A	2j2pE-4xgcD: undetectable 2j2pF-4xgcD: undetectable	2j2pE-4xgcD: 20.27 2j2pF-4xgcD: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYM_A_1UNA1001_3 (PROTEASE RETROPEPSIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	3 / 3	ASP E 103 ASN E 100 THR E  76	None	0.75A	2pymB-4xgcE: undetectable	2pymB-4xgcE: 13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RIW_A_T44A1395_1 (THYROXINE-BINDING GLOBULIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 10	ALA C 143 LEU C 240 LEU C 238 LEU C 223 LEU C 209	None	0.80A	2riwA-4xgcC: undetectable 2riwB-4xgcC: undetectable	2riwA-4xgcC: 22.01 2riwB-4xgcC: 6.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0Z_O_C41O1327_2 (RENIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 8	TYR C 430 TYR C 444 SER C 440 THR C 441	None	1.11A	2v0zO-4xgcC: undetectable	2v0zO-4xgcC: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VQY_A_PARA1201_1 (AAC(6')-IB)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 12	GLY E  46 LEU E 249 TYR E 291 SER C 259 ASP E 243	CL  E 501 (-3.9A) None None None None	1.29A	2vqyA-4xgcE: undetectable	2vqyA-4xgcE: 19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W3A_B_TOPB1189_1 (DIHYDROFOLATE REDUCTASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 10	ALA C 248 GLU C 213 ILE C 224 LEU C 238 THR C 244	None	1.03A	2w3aB-4xgcC: undetectable	2w3aB-4xgcC: 15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_B_DIFB1374_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 (Drosophila melanogaster)	4 / 6	MET B 344 PRO B 341 ILE B 346 LEU B 463	None	1.33A	2wekB-4xgcB: 2.3	2wekB-4xgcB: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN6_A_T44A1370_1 (THYROXINE-BINDING GLOBULIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 10	ALA C 143 LEU C 240 LEU C 238 LEU C 223 LEU C 209	None	0.76A	2xn6A-4xgcC: undetectable 2xn6B-4xgcC: undetectable	2xn6A-4xgcC: 22.32 2xn6B-4xgcC: 4.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN7_A_T44A1355_1 (THYROXINE-BINDING GLOBULIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 10	ALA C 143 LEU C 240 LEU C 238 LEU C 223 LEU C 209	None	0.82A	2xn7A-4xgcC: undetectable 2xn7B-4xgcC: undetectable	2xn7A-4xgcC: 22.32 2xn7B-4xgcC: 4.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_B_ACHB1211_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster; Drosophila melanogaster)	4 / 8	TYR C 307 GLN B 477 ILE C 606 SER C 310	None	1.11A	2xz5B-4xgcC: undetectable 2xz5E-4xgcC: undetectable	2xz5B-4xgcC: 14.89 2xz5E-4xgcC: 14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_E_ACHE1211_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster; Drosophila melanogaster)	4 / 7	GLN B 477 ILE C 606 SER C 310 TYR C 307	None	1.11A	2xz5D-4xgcB: undetectable 2xz5E-4xgcB: undetectable	2xz5D-4xgcB: 20.68 2xz5E-4xgcB: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_A_ZMRA1776_2 (NEURAMINIDASE A)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ARG C 180 ASP B 416 ILE B 418 LEU B 454	None	1.00A	2ya7A-4xgcC: undetectable	2ya7A-4xgcC: 19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_D_ZMRD1776_2 (NEURAMINIDASE A)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ARG C 180 ASP B 416 ILE B 418 LEU B 454	None	1.02A	2ya7D-4xgcC: undetectable	2ya7D-4xgcC: 19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z9W_A_PXLA1197_1 (ASPARTATE AMINOTRANSFERASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	5 / 11	GLU A 724 PRO A 723 LEU A 737 THR A 741 SER A 597	None	1.32A	2z9wA-4xgcA: undetectable	2z9wA-4xgcA: 22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ILE C 369 TYR C 384 THR C 380 LEU C 379	None	0.78A	3ag1N-4xgcC: 2.9 3ag1W-4xgcC: undetectable	3ag1N-4xgcC: 20.24 3ag1W-4xgcC: 6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 7	ILE D 143 LEU D 178 TYR D 250 THR D  24	None	0.97A	3ag2N-4xgcD: undetectable 3ag2W-4xgcD: undetectable	3ag2N-4xgcD: 21.64 3ag2W-4xgcD: 9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 7	ILE D 143 LEU D 178 TYR D 250 THR D  24	None	1.02A	3ag4N-4xgcD: undetectable 3ag4W-4xgcD: undetectable	3ag4N-4xgcD: 21.64 3ag4W-4xgcD: 9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BCR_A_AZZA940_1 (GLYCOGEN PHOSPHORYLASE, MUSCLE FORM)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 5	ASN B 484 PHE B 351 GLY C 317 TYR C 320	None	1.14A	3bcrA-4xgcB: undetectable	3bcrA-4xgcB: 17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CFQ_A_DIFA1_1 (TRANSTHYRETIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	LEU C 413 ALA C 466 LEU C 410 THR C 470	None	1.08A	3cfqA-4xgcC: undetectable	3cfqA-4xgcC: 11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD1_A_CFFA903_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASN B 484 PHE B 351 GLY C 317 TYR C 320	None	1.09A	3dd1A-4xgcB: undetectable	3dd1A-4xgcB: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDS_A_CFFA904_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASN B 484 PHE B 351 GLY C 317 TYR C 320	None	1.09A	3ddsA-4xgcB: undetectable	3ddsA-4xgcB: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDS_B_CFFB903_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASN B 484 PHE B 351 GLY C 317 TYR C 320	None	1.12A	3ddsB-4xgcB: undetectable	3ddsB-4xgcB: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDW_A_CFFA903_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASN B 484 PHE B 351 GLY C 317 TYR C 320	None	1.10A	3ddwA-4xgcB: undetectable	3ddwA-4xgcB: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDW_B_CFFB903_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASN B 484 PHE B 351 GLY C 317 TYR C 320	None	1.12A	3ddwB-4xgcB: undetectable	3ddwB-4xgcB: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DEU_A_SALA301_1 (TRANSCRIPTIONAL REGULATOR SLYA)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ILE C 659 TRP C 664 VAL C 648 HIS C 652	None	1.18A	3deuA-4xgcC: 5.4	3deuA-4xgcC: 13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWX_A_EPAA1_1 (PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA)))	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	5 / 10	PHE D 127 LEU D  84 VAL D  86 VAL D 142 LEU D 132	None	1.04A	3gwxA-4xgcD: undetectable	3gwxA-4xgcD: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HGG_A_CHDA211_0 (CMER)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 7	CYH D 219 PHE D 212 PHE D 304 TYR D 300	None	1.37A	3hggA-4xgcD: undetectable	3hggA-4xgcD: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_A_TFPA202_1 (PROTEIN S100-A4)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	LEU C 359 ILE C 590 CYH C 396 GLU C 592 LEU C 593	None	1.22A	3ko0A-4xgcC: 2.6 3ko0B-4xgcC: 2.6 3ko0C-4xgcC: 2.6 3ko0D-4xgcC: 2.7	3ko0A-4xgcC: 8.97 3ko0B-4xgcC: 8.97 3ko0C-4xgcC: 8.97 3ko0D-4xgcC: 8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_I_TFPI202_1 (PROTEIN S100-A4)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	LEU C 359 ILE C 590 CYH C 396 GLU C 592 LEU C 593	None	1.23A	3ko0G-4xgcC: 2.7 3ko0H-4xgcC: 2.7 3ko0I-4xgcC: 2.7 3ko0J-4xgcC: 2.5	3ko0G-4xgcC: 8.97 3ko0H-4xgcC: 8.97 3ko0I-4xgcC: 8.97 3ko0J-4xgcC: 8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_L_TFPL202_1 (PROTEIN S100-A4)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	GLU C 592 LEU C 593 LEU C 359 ILE C 590 CYH C 396	None	1.21A	3ko0K-4xgcC: 2.6 3ko0L-4xgcC: 2.6 3ko0M-4xgcC: 2.7 3ko0N-4xgcC: 2.6	3ko0K-4xgcC: 8.97 3ko0L-4xgcC: 8.97 3ko0M-4xgcC: 8.97 3ko0N-4xgcC: 8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_M_TFPM202_1 (PROTEIN S100-A4)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	LEU C 359 ILE C 590 CYH C 396 GLU C 592 LEU C 593	None	1.21A	3ko0M-4xgcC: 2.7 3ko0N-4xgcC: 2.6 3ko0O-4xgcC: 2.6 3ko0P-4xgcC: 2.7	3ko0M-4xgcC: 8.97 3ko0N-4xgcC: 8.97 3ko0O-4xgcC: 8.97 3ko0P-4xgcC: 8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_P_TFPP202_1 (PROTEIN S100-A4)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	GLU C 592 LEU C 593 LEU C 359 ILE C 590 CYH C 396	None	1.18A	3ko0M-4xgcC: 2.7 3ko0N-4xgcC: 2.7 3ko0O-4xgcC: 2.6 3ko0P-4xgcC: 2.7	3ko0M-4xgcC: 8.97 3ko0N-4xgcC: 8.97 3ko0O-4xgcC: 8.97 3ko0P-4xgcC: 8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L4D_D_TPFD490_1 (STEROL 14-ALPHA DEMETHYLASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 8	MET E  80 ALA E 128 LEU E 139 MET E 134	None	0.95A	3l4dD-4xgcE: undetectable	3l4dD-4xgcE: 22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M0W_C_P77C203_1 (PROTEIN S100-A4)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 10	SER C 361 PHE C 362 ILE C 356 GLU C 592 LEU C 593	None	1.38A	3m0wC-4xgcC: 2.9 3m0wD-4xgcC: 3.6 3m0wE-4xgcC: 3.6 3m0wF-4xgcC: 3.6	3m0wC-4xgcC: 8.82 3m0wD-4xgcC: 8.82 3m0wE-4xgcC: 8.82 3m0wF-4xgcC: 8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDT_A_VORA506_1 (CHOLESTEROL 24-HYDROXYLASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 9	VAL E 236 SER E 235 ILE E 279 ALA E 280 ALA E 286	None	1.27A	3mdtA-4xgcE: undetectable	3mdtA-4xgcE: 22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N0H_A_TOPA187_1 (DIHYDROFOLATE REDUCTASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 11	ALA C 248 GLU C 213 ILE C 224 LEU C 238 THR C 244	None	0.99A	3n0hA-4xgcC: undetectable	3n0hA-4xgcC: 16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 6	GLU E 320 PHE C 309 ALA C 270 ALA C 271	None	1.13A	3ns1C-4xgcE: undetectable	3ns1C-4xgcE: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OCT_A_1N1A663_2 (TYROSINE-PROTEIN KINASE BTK)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 (Drosophila melanogaster)	4 / 5	PHE B 485 ILE B 346 ASN B 436 PHE B 351	None	1.24A	3octA-4xgcB: undetectable	3octA-4xgcB: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P2K_A_SAMA6735_0 (16S RRNA METHYLASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	PRO C  48 ALA C 331 LEU C 342 THR C 349 LEU C 348	None	0.90A	3p2kA-4xgcC: undetectable	3p2kA-4xgcC: 15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P2K_B_SAMB6735_0 (16S RRNA METHYLASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	PRO C  48 ALA C 331 LEU C 342 THR C 349 LEU C 348	None	0.89A	3p2kB-4xgcC: undetectable	3p2kB-4xgcC: 15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QJ7_A_SPMA264_1 (THYMIDYLATE SYNTHASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 8	ALA E 325 GLN E 406 LEU E 321 ASP C 308	None	1.03A	3qj7A-4xgcE: undetectable 3qj7D-4xgcE: undetectable	3qj7A-4xgcE: 19.87 3qj7D-4xgcE: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXV_D_MTXD2000_2 (ANTI-METHOTREXATE CDR1-4 GRAFT VHH)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	3 / 3	LEU A 905 ARG A 692 ASN A 718	None	0.60A	3qxvD-4xgcA: undetectable	3qxvD-4xgcA: 15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RFA_A_SAMA406_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE N)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	5 / 12	PHE D 375 CYH D 349 GLU D 449 SER D 382 ILE D 392	None	1.45A	3rfaA-4xgcD: 2.0	3rfaA-4xgcD: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3V_A_TOPA187_1 (DIHYDROFOLATE REDUCTASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	ALA C 248 GLU C 213 ILE C 224 LEU C 238 THR C 244	None	0.99A	3s3vA-4xgcC: undetectable	3s3vA-4xgcC: 16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S43_A_478A401_2 (PROTEASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	5 / 10	LEU A 890 ILE A 904 VAL A 857 ILE A 835 ILE A 891	None	1.00A	3s43B-4xgcA: undetectable	3s43B-4xgcA: 13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UT5_D_LOCD502_1 (TUBULIN BETA CHAIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	LEU C 292 LEU C 322 ALA C  56 ALA C 289 ILE C  60	None	1.17A	3ut5D-4xgcC: undetectable	3ut5D-4xgcC: 21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_A_ACTA505_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	3 / 3	THR D  63 ASN D  67 GLU D 147	None	0.56A	3v4tA-4xgcD: undetectable 3v4tC-4xgcD: undetectable	3v4tA-4xgcD: 22.95 3v4tC-4xgcD: 22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_C_SAMC401_0 (MNMC2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster; Drosophila melanogaster)	5 / 12	GLY D  56 LEU D  65 GLY D  61 ALA A 825 LEU D 184	None	1.15A	3vywC-4xgcD: undetectable	3vywC-4xgcD: 23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_C_SAMC401_1 (MNMC2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster; Drosophila melanogaster)	4 / 6	GLY D 333 ASP D 295 ASP D 335 GLU E 174	None	1.01A	3vywC-4xgcD: undetectable	3vywC-4xgcD: 23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_A_VIVA301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 11	LEU E  84 ILE E  26 ILE E 156 VAL E 125 LEU E 157	None	1.06A	3w67A-4xgcE: 2.0	3w67A-4xgcE: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_B_VIVB301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 12	LEU E  84 ILE E  26 ILE E 156 VAL E 125 LEU E 157	None	1.08A	3w67B-4xgcE: undetectable	3w67B-4xgcE: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_B_W9TB502_1 (HEMOLYTIC LECTIN CEL-III)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASP B 467 GLY B 359 LEU C 703 GLU B 499	None	1.09A	3w9tB-4xgcB: undetectable	3w9tB-4xgcB: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_E_W9TE502_1 (HEMOLYTIC LECTIN CEL-III)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASP B 467 GLY B 359 LEU C 703 GLU B 499	None	1.08A	3w9tE-4xgcB: undetectable	3w9tE-4xgcB: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_F_W9TF503_1 (HEMOLYTIC LECTIN CEL-III)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	ASP B 467 GLY B 359 LEU C 703 GLU B 499	None	1.08A	3w9tF-4xgcB: undetectable	3w9tF-4xgcB: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 6	ILE D 143 LEU D 178 TYR D 250 THR D  24	None	0.95A	3wg7A-4xgcD: undetectable 3wg7J-4xgcD: undetectable	3wg7A-4xgcD: 21.64 3wg7J-4xgcD: 9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A6E_A_SAMA1349_1 (HYDROXYINDOLE O-METHYLTRANSFERASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	3 / 3	TYR A 595 ASP A 687 ASP A 684	None	0.73A	4a6eA-4xgcA: 4.4	4a6eA-4xgcA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1478_0 (TRANSLATION ELONGATION FACTOR SELB)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 6	ASP D  96 THR D 104 ILE D 103 THR D 159	None	1.04A	4acbC-4xgcD: undetectable	4acbC-4xgcD: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AX8_A_SAMA1474_1 (WBDD)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 6	GLN E 182 ARG E  15 GLU E 164 LEU E 180	None	1.07A	4ax8A-4xgcE: undetectable	4ax8A-4xgcE: 23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZS_A_SAMA1475_1 (METHYLTRANSFERASE WBDD)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster; Drosophila melanogaster)	3 / 3	ARG E 132 ASP C 222 GLN C 221	None	0.87A	4azsA-4xgcE: undetectable	4azsA-4xgcE: 23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B3Q_A_NVPA999_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 7	VAL E 221 TYR E 229 TYR E 226 LEU E 203	None	1.11A	4b3qA-4xgcE: undetectable	4b3qA-4xgcE: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DX7_B_DM2B1104_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 (Drosophila melanogaster)	4 / 8	SER B 486 PHE B 431 ILE B 433 PHE B 368	None	0.99A	4dx7B-4xgcB: undetectable	4dx7B-4xgcB: 15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G0V_D_MIXD101_1 (DNA TOPOISOMERASE 2-BETA)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	4 / 6	GLY A 634 ASN A 718 GLU A 685 GLN A 650	None	1.20A	4g0vB-4xgcA: 3.2	4g0vB-4xgcA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_F_KANF301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 8	ASP C 136 ARG C 135 ASP B 416 GLU B 420	None	1.07A	4gkhF-4xgcC: undetectable	4gkhF-4xgcC: 15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I89_A_1FLA201_1 (TRANSTHYRETIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	LEU C 413 ALA C 466 LEU C 410 THR C 470	None	1.05A	4i89A-4xgcC: undetectable	4i89A-4xgcC: 12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JTR_A_IBPA401_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 (Drosophila melanogaster)	4 / 8	VAL B 538 TYR B 534 LEU B 516 LEU B 607	None	1.02A	4jtrA-4xgcB: undetectable	4jtrA-4xgcB: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K38_A_SAMA504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME KP18CYS PEPTIDE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 (Drosophila melanogaster; Drosophila melanogaster)	5 / 12	GLU A 851 LEU B 567 ILE B 533 LEU B 578 CYH B 562	None	1.25A	4k38A-4xgcA: undetectable 4k38D-4xgcA: undetectable	4k38A-4xgcA: 22.46 4k38D-4xgcA: 4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA505_0 (RNA POLYMERASE 3D-POL)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 (Drosophila melanogaster; Drosophila melanogaster)	3 / 3	CYH C 372 ASN C 370 LYS F 239	None	1.10A	4k50A-4xgcC: undetectable	4k50A-4xgcC: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 11	LEU C 283 LEU C 292 ARG C 427 CYH C 321 VAL C 602	None	1.38A	4mk4B-4xgcC: undetectable	4mk4B-4xgcC: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NX6_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster; Drosophila melanogaster)	4 / 4	ILE D 238 ASP D  22 ARG E 115 THR D  25	None	1.09A	4nx6A-4xgcD: undetectable	4nx6A-4xgcD: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NX7_A_FOLA202_1 (DIHYDROFOLATE REDUCTASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster; Drosophila melanogaster)	4 / 4	ILE D 238 ASP D  22 ARG E 115 THR D  25	None	1.12A	4nx7A-4xgcD: undetectable	4nx7A-4xgcD: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYN_A_RTLA201_0 (RETINOL-BINDING PROTEIN 2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster; Drosophila melanogaster)	5 / 12	PHE E 104 ILE E 123 THR C 184 LEU E  69 LEU E  96	None	1.32A	4qynA-4xgcE: undetectable	4qynA-4xgcE: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYN_B_RTLB201_0 (RETINOL-BINDING PROTEIN 2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster; Drosophila melanogaster)	5 / 12	PHE E 104 ILE E 123 THR C 184 LEU E  69 LEU E  96	None	1.36A	4qynB-4xgcE: undetectable	4qynB-4xgcE: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_C_RTLC201_0 (RETINOL-BINDING PROTEIN 2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster; Drosophila melanogaster)	5 / 12	ALA C 243 VAL E 441 LEU E 321 LEU E 416 LEU E 410	None	1.16A	4qzuC-4xgcC: undetectable	4qzuC-4xgcC: 11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTB_A_SAMA501_1 (HYDG PROTEIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 (Drosophila melanogaster; Drosophila melanogaster)	3 / 3	GLU A 639 ARG A 693 GLN B 577	None	0.95A	4rtbA-4xgcA: undetectable	4rtbA-4xgcA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WQ4_B_ACTB403_0 (TRNA N6-ADENOSINE THREONYLCARBAMOYLTRA NSFERASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	3 / 3	ARG C 427 ASP C 280 ARG C 426	None	0.64A	4wq4B-4xgcC: undetectable	4wq4B-4xgcC: 19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1I_D_LOCD502_1 (TUBULIN BETA CHAIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	LEU C 292 LEU C 322 ALA C  56 ALA C 289 ILE C  60	None	1.13A	4x1iD-4xgcC: undetectable	4x1iD-4xgcC: 21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4D_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 6	CYH D 439 ILE D 337 GLN D 435 ILE D 351	None	1.20A	4z4dA-4xgcD: undetectable	4z4dA-4xgcD: 20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A6I_A_TCWA1124_1 (TRANSTHYRETIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 6	LEU D 340 LEU D 343 SER D 344 VAL D 450	None	1.17A	5a6iA-4xgcD: undetectable	5a6iA-4xgcD: 15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 6	ILE D 143 LEU D 178 TYR D 250 THR D  24	None	0.96A	5b1aN-4xgcD: undetectable 5b1aW-4xgcD: undetectable	5b1aN-4xgcD: 21.64 5b1aW-4xgcD: 9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CYQ_A_T27A601_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 12	LEU E 139 VAL E 155 VAL E 125 TYR E  38 LEU E 143	None	1.33A	5cyqA-4xgcE: undetectable	5cyqA-4xgcE: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GTR_A_ESTA601_2 (ESTROGEN RECEPTOR)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 5	LEU D 100 LEU D  88 PHE D 121 LEU D 164	None	0.80A	5gtrA-4xgcD: undetectable	5gtrA-4xgcD: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNW_B_TA1B902_1 (TUBULIN BETA-2B CHAIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	5 / 12	LEU D  70 LEU D 178 SER D 168 LEU D  40 PRO D 174	None	1.10A	5hnwB-4xgcD: undetectable	5hnwB-4xgcD: 23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNY_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	5 / 12	LEU D  70 LEU D 178 SER D 168 LEU D  40 PRO D 174	None	1.09A	5hnyB-4xgcD: undetectable	5hnyB-4xgcD: 23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HPU_A_IPHA101_0 (INSULIN, CHAIN A INSULIN, CHAIN B)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 4	CYH D 219 LEU D 288 LEU D 279 ALA D 284	None	1.10A	5hpuA-4xgcD: undetectable 5hpuB-4xgcD: undetectable	5hpuA-4xgcD: 5.59 5hpuB-4xgcD: 7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IMS_B_ACTB713_0 (ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	3 / 3	GLY A 598 GLN A 743 LYS A 604	None	1.00A	5imsB-4xgcA: 2.8	5imsB-4xgcA: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_B_1GNB603_1 (PHIAB6 TAILSPIKE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	3 / 3	VAL D 327 GLU E  20 GLU E  24	None	0.81A	5jsdB-4xgcD: undetectable 5jsdC-4xgcD: undetectable	5jsdB-4xgcD: 20.50 5jsdC-4xgcD: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KKZ_E_ASCE1004_0 (CYTOCHROME B UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 7	HIS C 110 HIS C 312 ILE C 311 TYR C  72	None	0.96A	5kkzC-4xgcC: undetectable 5kkzE-4xgcC: undetectable	5kkzC-4xgcC: 14.67 5kkzE-4xgcC: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KKZ_K_ASCK1004_0 (CYTOCHROME B UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 7	HIS C 312 ILE C 311 TYR C  72 HIS C 110	None	0.98A	5kkzK-4xgcC: undetectable 5kkzQ-4xgcC: undetectable	5kkzK-4xgcC: 21.22 5kkzQ-4xgcC: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KKZ_O_ASCO1004_0 (CYTOCHROME B UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 7	HIS C 110 HIS C 312 ILE C 311 TYR C  72	None	0.86A	5kkzM-4xgcC: undetectable 5kkzO-4xgcC: undetectable	5kkzM-4xgcC: 14.67 5kkzO-4xgcC: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L4I_A_6J3A201_0 (TRANSTHYRETIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	LEU C 413 ALA C 466 LEU C 410 THR C 470	None	1.03A	5l4iA-4xgcC: undetectable	5l4iA-4xgcC: 12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L4I_B_6J3B201_0 (TRANSTHYRETIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	4 / 6	LEU C 413 ALA C 466 LEU C 410 THR C 470	None	1.00A	5l4iB-4xgcC: undetectable	5l4iB-4xgcC: 12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_F_Z80F401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	5 / 10	ILE A 612 VAL A 608 THR A 605 GLU A 685 ILE A 716	None	1.26A	5lg3F-4xgcA: undetectable	5lg3F-4xgcA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_G_Z80G401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	5 / 10	ILE A 612 VAL A 608 THR A 605 GLU A 685 ILE A 716	None	1.18A	5lg3G-4xgcA: undetectable	5lg3G-4xgcA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_H_Z80H401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	5 / 10	ILE A 612 VAL A 608 THR A 605 GLU A 685 ILE A 716	None	1.12A	5lg3H-4xgcA: undetectable	5lg3H-4xgcA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJB_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster; Drosophila melanogaster)	4 / 8	LEU E 102 LEU E 148 ILE D  85 GLN D 245	None	1.04A	5ljbA-4xgcE: undetectable	5ljbA-4xgcE: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMW_B_RBFB201_1 (GLYOXALASE/BLEOMYCIN RESISANCE PROTEIN/DIOXYGENASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 (Drosophila melanogaster)	4 / 7	ARG C 357 TYR F 225 GLU C 354 LEU F 233	None	1.01A	5umwB-4xgcC: 0.4 5umwE-4xgcC: 0.6	5umwB-4xgcC: 8.94 5umwE-4xgcC: 8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_B_C2FB3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (Drosophila melanogaster)	5 / 12	ASN A 718 ASP A 687 VAL A 697 GLY A 634 ASN A 633	None	1.19A	5vopB-4xgcA: 2.2	5vopB-4xgcA: 24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A7P_A_9SCA601_1 (SERUM ALBUMIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 1 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster; Drosophila melanogaster)	4 / 5	ASN A 828 TYR D  29 LEU D 218 SER D  60	None	1.31A	6a7pA-4xgcA: undetectable	6a7pA-4xgcA: 20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B54_A_OAQA302_0 (SULFOTRANSFERASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 (Drosophila melanogaster)	5 / 12	ILE C 576 LEU C 569 VAL C 463 LEU C 491 LEU C 474	None	1.18A	6b54A-4xgcC: undetectable	6b54A-4xgcC: 18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_A_ECLA1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 7	ILE E   4 LEU E   8 ILE E  37 ALA E  49	None	0.85A	6b5vA-4xgcE: undetectable 6b5vC-4xgcE: undetectable	6b5vA-4xgcE: 11.33 6b5vC-4xgcE: 11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_C_ECLC1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 7	ILE E   4 LEU E   8 ILE E  37 ALA E  49	None	0.85A	6b5vC-4xgcE: undetectable 6b5vD-4xgcE: 0.0	6b5vC-4xgcE: 11.33 6b5vD-4xgcE: 11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_D_ECLD1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	4 / 7	ALA E  49 ILE E   4 LEU E   8 ILE E  37	None	0.86A	6b5vB-4xgcE: undetectable 6b5vD-4xgcE: 0.0	6b5vB-4xgcE: 11.33 6b5vD-4xgcE: 11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_C_GMJC301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster; Drosophila melanogaster)	5 / 12	PHE E 418 VAL E 411 HIS E 412 LEU B 451 ALA B 447	None	1.14A	6djzC-4xgcE: undetectable	6djzC-4xgcE: 19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ECE_C_DVAC3010_0 (VLM2 DODECADEPSIPEPTIDE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	3 / 3	ALA E  89 PHE E 121 GLN E 119	None	0.84A	6eceA-4xgcE: undetectable	6eceA-4xgcE: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ELI_A_T27A701_1 (REVERSE TRANSCRIPTASE)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 12	LEU E 139 VAL E 155 VAL E 125 TYR E  38 LEU E 143	None	1.36A	6eliA-4xgcE: undetectable	6eliA-4xgcE: 11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_B_TA1B501_1 (TUBULIN BETA CHAIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 12	GLU E  73 LEU C 209 LEU C 240 LEU C 132 LEU C 140	None	1.06A	6ew0B-4xgcE: undetectable	6ew0B-4xgcE: 13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_D_TA1D501_1 (TUBULIN BETA CHAIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 12	GLU E  73 LEU C 209 LEU C 240 LEU C 132 LEU C 140	None	1.06A	6ew0D-4xgcE: undetectable	6ew0D-4xgcE: 13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_H_TA1H501_1 (TUBULIN BETA CHAIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 12	GLU E  73 LEU C 209 LEU C 240 LEU C 132 LEU C 140	None	1.06A	6ew0H-4xgcE: undetectable	6ew0H-4xgcE: 13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_I_TA1I501_1 (TUBULIN BETA CHAIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	5 / 12	GLU E  73 LEU C 209 LEU C 240 LEU C 132 LEU C 140	None	1.05A	6ew0I-4xgcE: undetectable	6ew0I-4xgcE: 13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_ACTA813_0 (GEPHYRIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	3 / 3	THR D 281 ALA D 321 LYS D 323	None	0.78A	6fgcA-4xgcD: undetectable	6fgcA-4xgcD: 21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA817_0 (GEPHYRIN)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	3 / 3	THR D 281 ALA D 321 LYS D 323	None	0.76A	6fgdA-4xgcD: undetectable	6fgdA-4xgcD: 21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNG_B_QPSB601_3 (-)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 2 (Drosophila melanogaster)	3 / 3	ASP B 400 ASP B 392 ASN B 444	None	0.66A	6gngB-4xgcB: undetectable	6gngB-4xgcB: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NJ9_K_SAMK500_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 5 (Drosophila melanogaster)	3 / 3	THR E 435 GLU E 422 ASN E 414	None	0.87A	6nj9K-4xgcE: undetectable	6nj9K-4xgcE: 19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4xgc	ORIGIN RECOGNITION COMPLEX SUBUNIT 4 (Drosophila melanogaster)	4 / 6	ILE D 143 LEU D 178 TYR D 250 THR D  24	None	1.04A	6nmfN-4xgcD: undetectable 6nmfW-4xgcD: undetectable	6nmfN-4xgcD: 21.64 6nmfW-4xgcD: 9.59