SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xgn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E6W_C_ESTC302_1
(SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		4 / 4 ALA A  87
GLN A 155
TYR A 158
LEU A 196
 EDO  A 301 ( 4.1A)
None
EDO  A 301 ( 4.2A)
None
 0.47A 1e6wC-4xgnA:
39.2		 1e6wC-4xgnA:
54.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 7 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 1gtfL-4xgnA:
undetectable
1gtfM-4xgnA:
undetectable		 1gtfL-4xgnA:
13.85
1gtfM-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 1gtfM-4xgnA:
undetectable
1gtfN-4xgnA:
undetectable		 1gtfM-4xgnA:
13.85
1gtfN-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 8 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 1gtfN-4xgnA:
undetectable
1gtfO-4xgnA:
undetectable		 1gtfN-4xgnA:
13.85
1gtfO-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 1gtfO-4xgnA:
undetectable
1gtfP-4xgnA:
undetectable		 1gtfO-4xgnA:
13.85
1gtfP-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 1gtfP-4xgnA:
undetectable
1gtfQ-4xgnA:
undetectable		 1gtfP-4xgnA:
13.85
1gtfQ-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 1gtfR-4xgnA:
undetectable
1gtfS-4xgnA:
undetectable		 1gtfR-4xgnA:
13.85
1gtfS-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 11 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 1gtfS-4xgnA:
undetectable
1gtfT-4xgnA:
undetectable		 1gtfS-4xgnA:
13.85
1gtfT-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 1gtfT-4xgnA:
undetectable
1gtfU-4xgnA:
undetectable		 1gtfT-4xgnA:
13.85
1gtfU-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 11 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 1gtfU-4xgnA:
undetectable
1gtfV-4xgnA:
undetectable		 1gtfU-4xgnA:
13.85
1gtfV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.13A 1gtfL-4xgnA:
undetectable
1gtfV-4xgnA:
undetectable		 1gtfL-4xgnA:
13.85
1gtfV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.16A 1gtnL-4xgnA:
undetectable
1gtnM-4xgnA:
undetectable		 1gtnL-4xgnA:
13.85
1gtnM-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.11A 1gtnO-4xgnA:
undetectable
1gtnP-4xgnA:
undetectable		 1gtnO-4xgnA:
13.85
1gtnP-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 1gtnQ-4xgnA:
undetectable
1gtnR-4xgnA:
undetectable		 1gtnQ-4xgnA:
13.85
1gtnR-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.17A 1gtnR-4xgnA:
undetectable
1gtnS-4xgnA:
undetectable		 1gtnR-4xgnA:
13.85
1gtnS-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 11 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 1gtnT-4xgnA:
undetectable
1gtnU-4xgnA:
undetectable		 1gtnT-4xgnA:
13.85
1gtnU-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 LEU A   9
LEU A  77
ILE A 181
THR A 115
ILE A 119
 None
 1.37A 1hzeA-4xgnA:
undetectable
1hzeB-4xgnA:
undetectable		 1hzeA-4xgnA:
17.58
1hzeB-4xgnA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 115
ILE A 119
LEU A   9
LEU A  77
ILE A 181
 None
 1.38A 1hzeA-4xgnA:
undetectable
1hzeB-4xgnA:
undetectable		 1hzeA-4xgnA:
17.58
1hzeB-4xgnA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 LEU A   9
LEU A  77
ILE A 181
THR A 115
ILE A 119
 None
 1.40A 1i18A-4xgnA:
undetectable
1i18B-4xgnA:
undetectable		 1i18A-4xgnA:
17.58
1i18B-4xgnA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 THR A 115
ILE A 119
LEU A   9
LEU A  77
ILE A 181
 None
 1.41A 1i18A-4xgnA:
undetectable
1i18B-4xgnA:
undetectable		 1i18A-4xgnA:
17.58
1i18B-4xgnA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		6 / 9 GLY A 114
VAL A  58
ALA A  64
LEU A   9
ALA A 122
LEU A  80
 None
NAD  A 300 (-3.6A)
None
None
None
None
 1.19A 1muoA-4xgnA:
undetectable		 1muoA-4xgnA:
23.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		9 / 11 GLY A  12
ALA A  14
SER A  15
ASP A  36
LEU A  37
ASP A  57
VAL A  58
ALA A  84
VAL A 110
 NAD  A 300 (-3.5A)
NAD  A 300 ( 4.0A)
NAD  A 300 (-2.5A)
NAD  A 300 (-2.7A)
NAD  A 300 (-4.2A)
NAD  A 300 (-3.5A)
NAD  A 300 (-3.6A)
NAD  A 300 (-3.4A)
NAD  A 300 ( 4.1A)
 0.36A 1uayA-4xgnA:
37.7		 1uayA-4xgnA:
54.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		9 / 10 GLY A  12
ALA A  14
SER A  15
ASP A  36
LEU A  37
ASP A  57
VAL A  58
ALA A  84
VAL A 110
 NAD  A 300 (-3.5A)
NAD  A 300 ( 4.0A)
NAD  A 300 (-2.5A)
NAD  A 300 (-2.7A)
NAD  A 300 (-4.2A)
NAD  A 300 (-3.5A)
NAD  A 300 (-3.6A)
NAD  A 300 (-3.4A)
NAD  A 300 ( 4.1A)
 0.40A 1uayB-4xgnA:
37.9		 1uayB-4xgnA:
54.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.11A 1utdN-4xgnA:
undetectable
1utdO-4xgnA:
undetectable		 1utdN-4xgnA:
13.85
1utdO-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.16A 1utdQ-4xgnA:
undetectable
1utdR-4xgnA:
undetectable		 1utdQ-4xgnA:
13.85
1utdR-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 1utdR-4xgnA:
undetectable
1utdS-4xgnA:
undetectable		 1utdR-4xgnA:
13.85
1utdS-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 1utdT-4xgnA:
undetectable
1utdU-4xgnA:
undetectable		 1utdT-4xgnA:
13.85
1utdU-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.11A 1utdU-4xgnA:
undetectable
1utdV-4xgnA:
undetectable		 1utdU-4xgnA:
13.85
1utdV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 11 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 1utdL-4xgnA:
undetectable
1utdV-4xgnA:
undetectable		 1utdL-4xgnA:
13.85
1utdV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VD0_B_D27B1200_0
(GLUTATHIONE-REQUIRIN
G PROSTAGLANDIN D
SYNTHASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 ALA A 123
TYR A 223
CYH A  83
THR A  11
LEU A   9
 None
None
NAD  A 300 (-4.9A)
None
None
 1.43A 2vd0B-4xgnA:
0.6		 2vd0B-4xgnA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 ASP A  36
ASN A  38
ALA A  14
ASP A  57
VAL A  58
 NAD  A 300 (-2.7A)
None
NAD  A 300 ( 4.0A)
NAD  A 300 (-3.5A)
NAD  A 300 (-3.6A)
 0.90A 3ay0A-4xgnA:
5.8		 3ay0A-4xgnA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A  13
ASP A  36
ASN A  38
ASP A  57
VAL A  58
 None
NAD  A 300 (-2.7A)
None
NAD  A 300 (-3.5A)
NAD  A 300 (-3.6A)
 1.04A 3ay0B-4xgnA:
6.1		 3ay0B-4xgnA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		4 / 5 ILE A 247
PRO A 212
PHE A 213
PRO A 215
 EDO  A 302 (-4.7A)
None
None
None
 1.16A 3bjwC-4xgnA:
undetectable		 3bjwC-4xgnA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		3 / 3 ASP A  36
ASP A  40
ASP A  57
 NAD  A 300 (-2.7A)
None
NAD  A 300 (-3.5A)
 0.79A 3douA-4xgnA:
8.8		 3douA-4xgnA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 12 ASN A  82
VAL A 227
ARG A 182
MET A 126
LEU A  77
 None
 1.41A 3h52A-4xgnA:
undetectable		 3h52A-4xgnA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  12
ASP A  36
LEU A  37
ASN A  38
ASP A  57
 NAD  A 300 (-3.5A)
NAD  A 300 (-2.7A)
NAD  A 300 (-4.2A)
None
NAD  A 300 (-3.5A)
 0.56A 3q87B-4xgnA:
6.5		 3q87B-4xgnA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  12
SER A  15
LEU A  37
ASN A  38
ASP A  57
 NAD  A 300 (-3.5A)
NAD  A 300 (-2.5A)
NAD  A 300 (-4.2A)
None
NAD  A 300 (-3.5A)
 1.13A 3q87B-4xgnA:
6.5		 3q87B-4xgnA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		4 / 6 ASP A  57
GLY A 114
VAL A 110
THR A  11
 NAD  A 300 (-3.5A)
None
NAD  A 300 ( 4.1A)
None
 1.12A 3vqrA-4xgnA:
3.8		 3vqrA-4xgnA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		4 / 5 ASP A  57
GLY A 114
VAL A 110
THR A  11
 NAD  A 300 (-3.5A)
None
NAD  A 300 ( 4.1A)
None
 1.13A 3vqrB-4xgnA:
5.4		 3vqrB-4xgnA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		4 / 7 SER A 145
GLN A 155
TYR A 158
MET A 195
 NAD  A 300 ( 3.8A)
None
EDO  A 301 ( 4.2A)
NAD  A 300 (-3.8A)
 0.65A 4hxyB-4xgnA:
3.0		 4hxyB-4xgnA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		3 / 3 ARG A 120
GLU A  61
ASN A 117
 None
 0.92A 4imaD-4xgnA:
2.8		 4imaD-4xgnA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		3 / 3 ARG A 120
GLU A  61
ASN A 117
 None
 0.89A 4ip7D-4xgnA:
undetectable		 4ip7D-4xgnA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		6 / 11 GLY A  12
GLY A  13
THR A  21
ASP A  36
LEU A  37
ASP A  57
 NAD  A 300 (-3.5A)
None
None
NAD  A 300 (-2.7A)
NAD  A 300 (-4.2A)
NAD  A 300 (-3.5A)
 1.16A 4pghA-4xgnA:
5.9		 4pghA-4xgnA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  12
THR A  21
ASP A  36
LEU A  37
ASP A  57
 NAD  A 300 (-3.5A)
None
NAD  A 300 (-2.7A)
NAD  A 300 (-4.2A)
NAD  A 300 (-3.5A)
 1.21A 4pghB-4xgnA:
5.5		 4pghB-4xgnA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  42
ASN A  38
ALA A  71
THR A  72
ALA A  67
 None
 1.12A 4uckB-4xgnA:
4.2		 4uckB-4xgnA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.19A 5eeuA-4xgnA:
undetectable
5eeuB-4xgnA:
undetectable		 5eeuA-4xgnA:
13.85
5eeuB-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5eeuB-4xgnA:
undetectable
5eeuC-4xgnA:
undetectable		 5eeuB-4xgnA:
13.85
5eeuC-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.11A 5eeuL-4xgnA:
undetectable
5eeuV-4xgnA:
undetectable		 5eeuL-4xgnA:
13.85
5eeuV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5eeuL-4xgnA:
undetectable
5eeuM-4xgnA:
undetectable		 5eeuL-4xgnA:
13.85
5eeuM-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5eeuP-4xgnA:
undetectable
5eeuQ-4xgnA:
undetectable		 5eeuP-4xgnA:
13.85
5eeuQ-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eeuQ-4xgnA:
undetectable
5eeuR-4xgnA:
undetectable		 5eeuQ-4xgnA:
13.85
5eeuR-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eeuR-4xgnA:
undetectable
5eeuS-4xgnA:
undetectable		 5eeuR-4xgnA:
13.85
5eeuS-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.11A 5eeuS-4xgnA:
undetectable
5eeuT-4xgnA:
undetectable		 5eeuS-4xgnA:
13.85
5eeuT-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eeuT-4xgnA:
undetectable
5eeuU-4xgnA:
undetectable		 5eeuT-4xgnA:
13.85
5eeuU-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5eeuU-4xgnA:
undetectable
5eeuV-4xgnA:
undetectable		 5eeuU-4xgnA:
13.85
5eeuV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5eevB-4xgnA:
undetectable
5eevC-4xgnA:
undetectable		 5eevB-4xgnA:
13.85
5eevC-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5eevL-4xgnA:
undetectable
5eevM-4xgnA:
undetectable		 5eevL-4xgnA:
13.85
5eevM-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5eevP-4xgnA:
undetectable
5eevQ-4xgnA:
undetectable		 5eevP-4xgnA:
13.85
5eevQ-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eevQ-4xgnA:
undetectable
5eevR-4xgnA:
undetectable		 5eevQ-4xgnA:
13.85
5eevR-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eevR-4xgnA:
undetectable
5eevS-4xgnA:
undetectable		 5eevR-4xgnA:
13.85
5eevS-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eevS-4xgnA:
undetectable
5eevT-4xgnA:
undetectable		 5eevS-4xgnA:
13.85
5eevT-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eevT-4xgnA:
undetectable
5eevU-4xgnA:
undetectable		 5eevT-4xgnA:
13.85
5eevU-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 5eevU-4xgnA:
undetectable
5eevV-4xgnA:
undetectable		 5eevU-4xgnA:
13.85
5eevV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5eewB-4xgnA:
undetectable
5eewC-4xgnA:
undetectable		 5eewB-4xgnA:
13.85
5eewC-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5eewL-4xgnA:
undetectable
5eewM-4xgnA:
undetectable		 5eewL-4xgnA:
13.85
5eewM-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5eewP-4xgnA:
undetectable
5eewQ-4xgnA:
undetectable		 5eewP-4xgnA:
13.85
5eewQ-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eewQ-4xgnA:
undetectable
5eewR-4xgnA:
undetectable		 5eewQ-4xgnA:
13.85
5eewR-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.11A 5eewR-4xgnA:
undetectable
5eewS-4xgnA:
undetectable		 5eewR-4xgnA:
13.85
5eewS-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eewS-4xgnA:
undetectable
5eewT-4xgnA:
undetectable		 5eewS-4xgnA:
13.85
5eewT-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eewT-4xgnA:
undetectable
5eewU-4xgnA:
undetectable		 5eewT-4xgnA:
13.85
5eewU-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 5eewU-4xgnA:
undetectable
5eewV-4xgnA:
undetectable		 5eewU-4xgnA:
13.85
5eewV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5eexB-4xgnA:
undetectable
5eexC-4xgnA:
undetectable		 5eexB-4xgnA:
13.85
5eexC-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.12A 5eexL-4xgnA:
undetectable
5eexV-4xgnA:
undetectable		 5eexL-4xgnA:
13.85
5eexV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5eexL-4xgnA:
undetectable
5eexM-4xgnA:
undetectable		 5eexL-4xgnA:
13.85
5eexM-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5eexP-4xgnA:
undetectable
5eexQ-4xgnA:
undetectable		 5eexP-4xgnA:
13.85
5eexQ-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eexQ-4xgnA:
undetectable
5eexR-4xgnA:
undetectable		 5eexQ-4xgnA:
13.85
5eexR-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eexR-4xgnA:
undetectable
5eexS-4xgnA:
undetectable		 5eexR-4xgnA:
13.85
5eexS-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eexS-4xgnA:
undetectable
5eexT-4xgnA:
undetectable		 5eexS-4xgnA:
13.85
5eexT-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eexT-4xgnA:
undetectable
5eexU-4xgnA:
undetectable		 5eexT-4xgnA:
13.85
5eexU-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 5eexU-4xgnA:
undetectable
5eexV-4xgnA:
undetectable		 5eexU-4xgnA:
13.85
5eexV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5eeyB-4xgnA:
undetectable
5eeyC-4xgnA:
undetectable		 5eeyB-4xgnA:
13.85
5eeyC-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.12A 5eeyL-4xgnA:
undetectable
5eeyV-4xgnA:
undetectable		 5eeyL-4xgnA:
13.85
5eeyV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5eeyL-4xgnA:
undetectable
5eeyM-4xgnA:
undetectable		 5eeyL-4xgnA:
13.85
5eeyM-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5eeyP-4xgnA:
undetectable
5eeyQ-4xgnA:
undetectable		 5eeyP-4xgnA:
13.85
5eeyQ-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eeyQ-4xgnA:
undetectable
5eeyR-4xgnA:
undetectable		 5eeyQ-4xgnA:
13.85
5eeyR-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.11A 5eeyR-4xgnA:
undetectable
5eeyS-4xgnA:
undetectable		 5eeyR-4xgnA:
13.85
5eeyS-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eeyS-4xgnA:
undetectable
5eeyT-4xgnA:
undetectable		 5eeyS-4xgnA:
13.85
5eeyT-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eeyT-4xgnA:
undetectable
5eeyU-4xgnA:
undetectable		 5eeyT-4xgnA:
13.85
5eeyU-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 5eeyU-4xgnA:
undetectable
5eeyV-4xgnA:
undetectable		 5eeyU-4xgnA:
13.85
5eeyV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5eezB-4xgnA:
undetectable
5eezC-4xgnA:
undetectable		 5eezB-4xgnA:
13.85
5eezC-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 8 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.12A 5eezL-4xgnA:
undetectable
5eezV-4xgnA:
undetectable		 5eezL-4xgnA:
13.85
5eezV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5eezL-4xgnA:
undetectable
5eezM-4xgnA:
undetectable		 5eezL-4xgnA:
13.85
5eezM-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5eezP-4xgnA:
undetectable
5eezQ-4xgnA:
undetectable		 5eezP-4xgnA:
13.85
5eezQ-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eezQ-4xgnA:
undetectable
5eezR-4xgnA:
undetectable		 5eezQ-4xgnA:
13.85
5eezR-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5eezR-4xgnA:
undetectable
5eezS-4xgnA:
undetectable		 5eezR-4xgnA:
13.85
5eezS-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eezS-4xgnA:
undetectable
5eezT-4xgnA:
undetectable		 5eezS-4xgnA:
13.85
5eezT-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5eezT-4xgnA:
undetectable
5eezU-4xgnA:
undetectable		 5eezT-4xgnA:
13.85
5eezU-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 5eezU-4xgnA:
undetectable
5eezV-4xgnA:
undetectable		 5eezU-4xgnA:
13.85
5eezV-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5ef0B-4xgnA:
undetectable
5ef0C-4xgnA:
undetectable		 5ef0B-4xgnA:
13.85
5ef0C-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.12A 5ef0L-4xgnA:
undetectable
5ef0V-4xgnA:
undetectable		 5ef0L-4xgnA:
13.85
5ef0V-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5ef0L-4xgnA:
undetectable
5ef0M-4xgnA:
undetectable		 5ef0L-4xgnA:
13.85
5ef0M-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5ef0P-4xgnA:
undetectable
5ef0Q-4xgnA:
undetectable		 5ef0P-4xgnA:
13.85
5ef0Q-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5ef0Q-4xgnA:
undetectable
5ef0R-4xgnA:
undetectable		 5ef0Q-4xgnA:
13.85
5ef0R-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.11A 5ef0R-4xgnA:
undetectable
5ef0S-4xgnA:
undetectable		 5ef0R-4xgnA:
13.85
5ef0S-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5ef0S-4xgnA:
undetectable
5ef0T-4xgnA:
undetectable		 5ef0S-4xgnA:
13.85
5ef0T-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5ef0T-4xgnA:
undetectable
5ef0U-4xgnA:
undetectable		 5ef0T-4xgnA:
13.85
5ef0U-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 5ef0U-4xgnA:
undetectable
5ef0V-4xgnA:
undetectable		 5ef0U-4xgnA:
13.85
5ef0V-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5ef1B-4xgnA:
undetectable
5ef1C-4xgnA:
undetectable		 5ef1B-4xgnA:
13.85
5ef1C-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 8 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.12A 5ef1L-4xgnA:
undetectable
5ef1V-4xgnA:
undetectable		 5ef1L-4xgnA:
13.85
5ef1V-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5ef1L-4xgnA:
undetectable
5ef1M-4xgnA:
undetectable		 5ef1L-4xgnA:
13.85
5ef1M-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5ef1P-4xgnA:
undetectable
5ef1Q-4xgnA:
undetectable		 5ef1P-4xgnA:
13.85
5ef1Q-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5ef1Q-4xgnA:
undetectable
5ef1R-4xgnA:
undetectable		 5ef1Q-4xgnA:
13.85
5ef1R-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.11A 5ef1R-4xgnA:
undetectable
5ef1S-4xgnA:
undetectable		 5ef1R-4xgnA:
13.85
5ef1S-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5ef1S-4xgnA:
undetectable
5ef1T-4xgnA:
undetectable		 5ef1S-4xgnA:
13.85
5ef1T-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5ef1T-4xgnA:
undetectable
5ef1U-4xgnA:
undetectable		 5ef1T-4xgnA:
13.85
5ef1U-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 5ef1U-4xgnA:
undetectable
5ef1V-4xgnA:
undetectable		 5ef1U-4xgnA:
13.85
5ef1V-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5ef2B-4xgnA:
undetectable
5ef2C-4xgnA:
undetectable		 5ef2B-4xgnA:
13.85
5ef2C-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 8 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.12A 5ef2L-4xgnA:
undetectable
5ef2V-4xgnA:
undetectable		 5ef2L-4xgnA:
13.85
5ef2V-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5ef2L-4xgnA:
undetectable
5ef2M-4xgnA:
undetectable		 5ef2L-4xgnA:
13.85
5ef2M-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5ef2P-4xgnA:
undetectable
5ef2Q-4xgnA:
undetectable		 5ef2P-4xgnA:
13.85
5ef2Q-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5ef2Q-4xgnA:
undetectable
5ef2R-4xgnA:
undetectable		 5ef2Q-4xgnA:
13.85
5ef2R-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.11A 5ef2R-4xgnA:
undetectable
5ef2S-4xgnA:
undetectable		 5ef2R-4xgnA:
13.85
5ef2S-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5ef2S-4xgnA:
undetectable
5ef2T-4xgnA:
undetectable		 5ef2S-4xgnA:
13.85
5ef2T-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5ef2T-4xgnA:
undetectable
5ef2U-4xgnA:
undetectable		 5ef2T-4xgnA:
13.85
5ef2U-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 5ef2U-4xgnA:
undetectable
5ef2V-4xgnA:
undetectable		 5ef2U-4xgnA:
13.85
5ef2V-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 THR A 169
SER A 142
GLY A 164
ALA A 144
THR A 115
 None
 1.14A 5ef3B-4xgnA:
undetectable
5ef3C-4xgnA:
undetectable		 5ef3B-4xgnA:
13.85
5ef3C-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5ef3L-4xgnA:
undetectable
5ef3M-4xgnA:
undetectable		 5ef3L-4xgnA:
13.85
5ef3M-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.15A 5ef3P-4xgnA:
undetectable
5ef3Q-4xgnA:
undetectable		 5ef3P-4xgnA:
13.85
5ef3Q-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5ef3Q-4xgnA:
undetectable
5ef3R-4xgnA:
undetectable		 5ef3Q-4xgnA:
13.85
5ef3R-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.10A 5ef3R-4xgnA:
undetectable
5ef3S-4xgnA:
undetectable		 5ef3R-4xgnA:
13.85
5ef3S-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.12A 5ef3S-4xgnA:
undetectable
5ef3T-4xgnA:
undetectable		 5ef3S-4xgnA:
13.85
5ef3T-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.13A 5ef3T-4xgnA:
undetectable
5ef3U-4xgnA:
undetectable		 5ef3T-4xgnA:
13.85
5ef3U-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 10 GLY A 164
ALA A 144
THR A 115
THR A 169
SER A 142
 None
 1.14A 5ef3U-4xgnA:
undetectable
5ef3V-4xgnA:
undetectable		 5ef3U-4xgnA:
13.85
5ef3V-4xgnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 9 VAL A  32
LEU A  25
PHE A 231
VAL A  81
ILE A  10
 None
 1.17A 5om2A-4xgnA:
undetectable
5om2B-4xgnA:
undetectable		 5om2A-4xgnA:
18.18
5om2B-4xgnA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  12
GLY A  20
ASP A  36
LEU A  37
ASP A  57
 NAD  A 300 (-3.5A)
None
NAD  A 300 (-2.7A)
NAD  A 300 (-4.2A)
NAD  A 300 (-3.5A)
 0.68A 5yniA-4xgnA:
5.2		 5yniA-4xgnA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  12
GLY A  20
ASP A  36
LEU A  37
CYH A  56
 NAD  A 300 (-3.5A)
None
NAD  A 300 (-2.7A)
NAD  A 300 (-4.2A)
None
 1.04A 5yniA-4xgnA:
5.2		 5yniA-4xgnA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  12
GLY A  20
ASP A  36
LEU A  37
ASP A  57
 NAD  A 300 (-3.5A)
None
NAD  A 300 (-2.7A)
NAD  A 300 (-4.2A)
NAD  A 300 (-3.5A)
 0.69A 5ynmA-4xgnA:
5.1		 5ynmA-4xgnA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 4xgn 3-HYDROXYACYL-COA
DEHYDROGENASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  12
GLY A  20
ASP A  36
LEU A  37
CYH A  56
 NAD  A 300 (-3.5A)
None
NAD  A 300 (-2.7A)
NAD  A 300 (-4.2A)
None
 1.05A 5ynmA-4xgnA:
5.1		 5ynmA-4xgnA:
21.66