SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xhv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)
4xhv LP20995P
(Drosophila
melanogaster)
4 / 8 VAL A1341
ARG A1304
GLY A1300
ALA A1303
None
0.93A 2xh9A-4xhvA:
undetectable
2xh9A-4xhvA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)
4xhv LP20995P
(Drosophila
melanogaster)
5 / 12 GLY A1272
GLY A1270
THR A1337
ILE A1296
LEU A1334
None
1.00A 5bw4A-4xhvA:
undetectable
5bw4A-4xhvA:
15.47