SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xia'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		4 / 7 VAL A 161
LEU A 179
LEU A 199
ALA A 234
 None
 0.83A 1j8uA-4xiaA:
undetectable		 1j8uA-4xiaA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		3 / 3 ASP A  56
THR A  89
GLU A 180
 None
SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
 0.88A 1pj7A-4xiaA:
undetectable		 1pj7A-4xiaA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 10 GLY A 287
HIS A 242
THR A  11
HIS A 290
THR A 132
 None
 1.25A 1utdQ-4xiaA:
undetectable
1utdR-4xiaA:
undetectable		 1utdQ-4xiaA:
12.47
1utdR-4xiaA:
12.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		10 / 10 TRP A  15
HIS A  53
PHE A  93
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
LYS A 294
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.9A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
None
 0.27A 1xidA-4xiaA:
57.6		 1xidA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 10 TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.29A 1xidA-4xiaA:
57.6		 1xidA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 HIS A  53
THR A  89
PHE A  93
VAL A 134
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 ( 4.9A)
SOR  A 400 (-4.5A)
None
 1.09A 1xihA-4xiaA:
57.5		 1xihA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.38A 1xihA-4xiaA:
57.5		 1xihA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
PHE A  93
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 ( 4.9A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.18A 1xihA-4xiaA:
57.5		 1xihA-4xiaA:
65.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 ILE A 231
ALA A 232
ALA A 234
GLN A 233
LEU A 199
HIS A 242
 None
 1.41A 1xiuB-4xiaA:
undetectable		 1xiuB-4xiaA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		4 / 7 ALA A 130
TYR A 173
TYR A 167
PHE A 133
 None
 1.17A 2ajvH-4xiaA:
undetectable
2ajvL-4xiaA:
undetectable		 2ajvH-4xiaA:
21.27
2ajvL-4xiaA:
18.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.23A 2xinA-4xiaA:
57.4		 2xinA-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
HIS A 219
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
 1.32A 2xinA-4xiaA:
57.4		 2xinA-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 216
HIS A 219
ASP A 256
ASP A 244
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
MG  A 399 ( 3.1A)
 1.33A 2xinA-4xiaA:
57.4		 2xinA-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.47A 2xinA-4xiaA:
57.4		 2xinA-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 12 HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
 1.36A 2xinB-4xiaA:
57.3		 2xinB-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.17A 2xinB-4xiaA:
57.3		 2xinB-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.45A 2xinB-4xiaA:
57.3		 2xinB-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 12 HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
 1.39A 2xinC-4xiaA:
57.4		 2xinC-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.22A 2xinC-4xiaA:
57.4		 2xinC-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.49A 2xinC-4xiaA:
57.4		 2xinC-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
GLU A 180
GLU A 216
HIS A 219
ASP A 256
ASP A 244
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
MG  A 399 ( 3.1A)
 1.50A 2xinD-4xiaA:
57.4		 2xinD-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.30A 2xinD-4xiaA:
57.4		 2xinD-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
HIS A 219
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
 1.30A 2xinD-4xiaA:
57.4		 2xinD-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.45A 2xinD-4xiaA:
57.4		 2xinD-4xiaA:
67.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		4 / 4 ASP A  73
GLY A  72
LYS A  69
GLU A  68
 None
 1.35A 3hznD-4xiaA:
undetectable		 3hznD-4xiaA:
20.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 HIS A  53
THR A  89
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.37A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 HIS A  53
THR A  89
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.37A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.15A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.35A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.19A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		9 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.59A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.16A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.20A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.32A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.40A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.18A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		9 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.59A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.37A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.29A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.11A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.20A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		9 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.72A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.14A 3ximD-4xiaA:
57.9		 3ximD-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.29A 3ximD-4xiaA:
57.9		 3ximD-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 TRP A  15
HIS A  53
THR A  89
TRP A 136
LYS A 182
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
SOR  A 400 ( 4.8A)
 0.75A 3ximD-4xiaA:
57.9		 3ximD-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.17A 3ximD-4xiaA:
57.9		 3ximD-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
ASN A 214
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
None
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.24A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.32A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.33A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
ASN A 214
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
None
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 0.16A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		10 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
ASN A 214
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
None
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.67A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		3 / 3 ARG A 394
HIS A 389
SER A 393
 None
 0.66A 4mjwA-4xiaA:
undetectable
4mjwB-4xiaA:
undetectable		 4mjwA-4xiaA:
25.09
4mjwB-4xiaA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		3 / 3 SER A 393
ARG A 394
HIS A 389
 None
 0.69A 4mjwA-4xiaA:
undetectable
4mjwB-4xiaA:
undetectable		 4mjwA-4xiaA:
25.09
4mjwB-4xiaA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		4 / 6 ARG A 326
ALA A 386
ASP A 272
SER A 338
 None
 0.90A 4ot2A-4xiaA:
undetectable		 4ot2A-4xiaA:
23.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 MET A  87
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.41A 4xiaA-4xiaA:
65.0		 4xiaA-4xiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.02A 4xiaA-4xiaA:
65.0		 4xiaA-4xiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.24A 4xiaB-4xiaA:
62.7		 4xiaB-4xiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 MET A  87
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.33A 4xiaB-4xiaA:
62.7		 4xiaB-4xiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.14A 4xiaB-4xiaA:
62.7		 4xiaB-4xiaA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 10 PHE A 259
VAL A 271
GLU A 275
LEU A 316
PHE A  10
 None
 1.33A 4zmeB-4xiaA:
undetectable		 4zmeB-4xiaA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 10 PHE A 259
VAL A 271
GLU A 275
LEU A 318
PHE A  10
 None
 1.32A 4zmeB-4xiaA:
undetectable		 4zmeB-4xiaA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 9 HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.33A 5nhaA-4xiaA:
38.9		 5nhaA-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.23A 5nhaA-4xiaA:
38.9		 5nhaA-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.24A 5nhaB-4xiaA:
38.8		 5nhaB-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.28A 5nhaB-4xiaA:
38.8		 5nhaB-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 HIS A  53
TRP A 136
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.35A 5nhaC-4xiaA:
38.8		 5nhaC-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.24A 5nhaC-4xiaA:
38.8		 5nhaC-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.28A 5nhaC-4xiaA:
38.8		 5nhaC-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 HIS A  53
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.40A 5nhaD-4xiaA:
38.9		 5nhaD-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.24A 5nhaD-4xiaA:
38.9		 5nhaD-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.28A 5nhaD-4xiaA:
38.9		 5nhaD-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		4 / 6 HIS A 242
HIS A 290
THR A  51
TRP A  15
 None
None
None
SOR  A 400 (-4.0A)
 1.31A 5ogjA-4xiaA:
undetectable		 5ogjA-4xiaA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 LEU A 179
LEU A 192
GLY A 198
GLY A 196
LEU A 205
 None
 1.03A 5uc1A-4xiaA:
undetectable		 5uc1A-4xiaA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 LEU A 179
LEU A 192
GLY A 198
GLY A 196
LEU A 205
 None
 1.03A 5uc1B-4xiaA:
undetectable		 5uc1B-4xiaA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 VAL A  88
PHE A  52
LEU A  78
GLY A 129
ALA A 130
 None
 1.44A 5x23A-4xiaA:
undetectable		 5x23A-4xiaA:
20.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.35A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.43A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.16A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.35A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.18A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		9 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.65A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.22A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 MET A  87
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.35A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 MET A  87
THR A  89
TRP A 136
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.41A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.19A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		10 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
HIS A 219
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.56A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
None
 1.21A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.27A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.35A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.14A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.52A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
GLU A 216
ASP A 256
ASP A 244
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
None
MG  A 399 ( 3.1A)
 1.39A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.35A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.10A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.20A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		10 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.61A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 ILE A 231
ALA A 232
ALA A 234
GLN A 233
LEU A 199
HIS A 242
 None
 1.49A 6a60D-4xiaA:
undetectable		 6a60D-4xiaA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		3 / 3 HIS A  53
ASN A  91
LEU A  92
 SOR  A 400 (-4.0A)
None
None
 0.89A 6f7lB-4xiaA:
undetectable		 6f7lB-4xiaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		4 / 8 TRP A  19
ASP A  56
ASP A 292
GLU A 180
 None
None
SOR  A 400 ( 2.7A)
MG  A 399 ( 2.5A)
 1.07A 6mn4C-4xiaA:
undetectable		 6mn4C-4xiaA:
23.25