SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xj5'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AXW_A_MTXA732_1 (THYMIDYLATE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	5 / 12	ILE A 328 LEU A 373 LEU A 322 GLY A 323 VAL A 282	None NA  A1015 (-4.1A) None EDO  A1011 (-3.4A) None	0.92A	1axwA-4xj5A: undetectable	1axwA-4xj5A: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K2S_B_H4BB2760_1 (NITRIC-OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.27A	1k2sA-4xj5A: undetectable 1k2sB-4xj5A: undetectable	1k2sA-4xj5A: 22.66 1k2sB-4xj5A: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LZZ_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.14A	1lzzA-4xj5A: undetectable 1lzzB-4xj5A: undetectable	1lzzA-4xj5A: 22.66 1lzzB-4xj5A: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M00_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	1m00A-4xj5A: undetectable 1m00B-4xj5A: undetectable	1m00A-4xj5A: 22.66 1m00B-4xj5A: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MMW_A_H4BA1760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.14A	1mmwA-4xj5A: undetectable 1mmwB-4xj5A: 1.9	1mmwA-4xj5A: 22.66 1mmwB-4xj5A: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6H_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	1p6hA-4xj5A: undetectable 1p6hB-4xj5A: undetectable	1p6hA-4xj5A: 22.78 1p6hB-4xj5A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6I_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	1p6iA-4xj5A: undetectable 1p6iB-4xj5A: undetectable	1p6iA-4xj5A: 22.78 1p6iB-4xj5A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6J_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.13A	1p6jA-4xj5A: undetectable 1p6jB-4xj5A: undetectable	1p6jA-4xj5A: 22.78 1p6jB-4xj5A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6J_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.17A	1p6jA-4xj5A: undetectable 1p6jB-4xj5A: undetectable	1p6jA-4xj5A: 22.78 1p6jB-4xj5A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS7_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.14A	1rs7A-4xj5A: undetectable 1rs7B-4xj5A: undetectable	1rs7A-4xj5A: 22.78 1rs7B-4xj5A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS7_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	1rs7A-4xj5A: undetectable 1rs7B-4xj5A: undetectable	1rs7A-4xj5A: 22.78 1rs7B-4xj5A: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQF_A_SAMA430_1 (SUN PROTEIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	3 / 3	PRO A 261 ASP A 345 ASP A 266	GH3  A1013 ( 3.9A) GH3  A1014 ( 4.4A) None	0.77A	1sqfA-4xj5A: undetectable	1sqfA-4xj5A: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLS_A_C2FA266_0 (THYMIDYLATE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	5 / 12	ILE A 328 LEU A 373 LEU A 322 GLY A 323 VAL A 282	None NA  A1015 (-4.1A) None EDO  A1011 (-3.4A) None	1.01A	1tlsA-4xj5A: undetectable	1tlsA-4xj5A: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLS_B_C2FB266_0 (THYMIDYLATE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	5 / 12	ILE A 328 LEU A 373 LEU A 322 GLY A 323 VAL A 282	None NA  A1015 (-4.1A) None EDO  A1011 (-3.4A) None	0.98A	1tlsB-4xj5A: undetectable	1tlsB-4xj5A: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TSN_A_C2FA266_0 (THYMIDYLATE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	5 / 12	ILE A 328 LEU A 373 LEU A 322 GLY A 323 VAL A 282	None NA  A1015 (-4.1A) None EDO  A1011 (-3.4A) None	1.03A	1tsnA-4xj5A: undetectable	1tsnA-4xj5A: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_A_SALA502_1 (SALICYLIC ACID-BINDING PROTEIN 2)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	3 / 3	LEU A 322 HIS A 278 LYS A 281	None EDO  A1012 ( 4.7A) None	0.75A	1y7iA-4xj5A: undetectable	1y7iA-4xj5A: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZVL_B_H4BB920_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.17A	1zvlA-4xj5A: undetectable 1zvlB-4xj5A: 1.5	1zvlA-4xj5A: 22.38 1zvlB-4xj5A: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZQ_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	1zzqA-4xj5A: undetectable 1zzqB-4xj5A: undetectable	1zzqA-4xj5A: 20.48 1zzqB-4xj5A: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZR_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	1zzrA-4xj5A: undetectable 1zzrB-4xj5A: undetectable	1zzrA-4xj5A: 20.48 1zzrB-4xj5A: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZR_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	1zzrA-4xj5A: undetectable 1zzrB-4xj5A: undetectable	1zzrA-4xj5A: 20.48 1zzrB-4xj5A: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZU_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	1zzuA-4xj5A: undetectable 1zzuB-4xj5A: 1.9	1zzuA-4xj5A: 20.48 1zzuB-4xj5A: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJG_B_ADNB1502_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	GLU A 375 LYS A 327 PRO A 374 ALA A 330	None	1.49A	2ejgB-4xj5A: undetectable	2ejgB-4xj5A: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HX3_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	2hx3A-4xj5A: undetectable 2hx3B-4xj5A: undetectable	2hx3A-4xj5A: 22.45 2hx3B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HX4_B_H4BB760_1 (NITRIC-OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.21A	2hx4A-4xj5A: undetectable 2hx4B-4xj5A: undetectable	2hx4A-4xj5A: 22.45 2hx4B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3N_B_H4BB760_1 (NITRIC-OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.19A	3b3nA-4xj5A: undetectable 3b3nB-4xj5A: undetectable	3b3nA-4xj5A: 22.45 3b3nB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3O_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	3b3oA-4xj5A: undetectable 3b3oB-4xj5A: undetectable	3b3oA-4xj5A: 22.45 3b3oB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3O_B_H4BB760_1 (NITRIC-OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.20A	3b3oA-4xj5A: undetectable 3b3oB-4xj5A: undetectable	3b3oA-4xj5A: 22.45 3b3oB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H0A_A_9RAA500_2 (RETINOIC ACID RECEPTOR RXR-ALPHA)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	3 / 3	ILE A 149 PHE A  47 HIS A 151	None	0.70A	3h0aA-4xj5A: undetectable	3h0aA-4xj5A: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT3_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.17A	3jt3A-4xj5A: undetectable 3jt3B-4xj5A: undetectable	3jt3A-4xj5A: 22.45 3jt3B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT4_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	3jt4A-4xj5A: undetectable 3jt4B-4xj5A: undetectable	3jt4A-4xj5A: 22.45 3jt4B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT4_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.16A	3jt4A-4xj5A: undetectable 3jt4B-4xj5A: undetectable	3jt4A-4xj5A: 22.45 3jt4B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT6_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.22A	3jt6A-4xj5A: undetectable 3jt6B-4xj5A: undetectable	3jt6A-4xj5A: 22.45 3jt6B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT8_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	3jt8A-4xj5A: undetectable 3jt8B-4xj5A: undetectable	3jt8A-4xj5A: 22.45 3jt8B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JTA_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.20A	3jtaA-4xj5A: undetectable 3jtaB-4xj5A: undetectable	3jtaA-4xj5A: 22.45 3jtaB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWT_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	3jwtA-4xj5A: undetectable 3jwtB-4xj5A: undetectable	3jwtA-4xj5A: 22.25 3jwtB-4xj5A: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWV_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.13A	3jwvA-4xj5A: undetectable 3jwvB-4xj5A: undetectable	3jwvA-4xj5A: 22.25 3jwvB-4xj5A: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX3_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.20A	3jx3A-4xj5A: undetectable 3jx3B-4xj5A: undetectable	3jx3A-4xj5A: 20.61 3jx3B-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX3_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.17A	3jx3A-4xj5A: undetectable 3jx3B-4xj5A: undetectable	3jx3A-4xj5A: 20.61 3jx3B-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX4_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.13A	3jx4A-4xj5A: undetectable 3jx4B-4xj5A: undetectable	3jx4A-4xj5A: 20.61 3jx4B-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX4_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.20A	3jx4A-4xj5A: undetectable 3jx4B-4xj5A: undetectable	3jx4A-4xj5A: 20.61 3jx4B-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX5_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	3jx5A-4xj5A: undetectable 3jx5B-4xj5A: undetectable	3jx5A-4xj5A: 20.61 3jx5B-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX5_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.14A	3jx5A-4xj5A: undetectable 3jx5B-4xj5A: undetectable	3jx5A-4xj5A: 20.61 3jx5B-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX6_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.10A	3jx6A-4xj5A: undetectable 3jx6B-4xj5A: undetectable	3jx6A-4xj5A: 20.61 3jx6B-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX6_B_H4BB761_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.24A	3jx6A-4xj5A: undetectable 3jx6B-4xj5A: undetectable	3jx6A-4xj5A: 20.61 3jx6B-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N2R_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	3n2rA-4xj5A: undetectable 3n2rB-4xj5A: undetectable	3n2rA-4xj5A: 22.45 3n2rB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5V_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.09A	3n5vA-4xj5A: undetectable 3n5vB-4xj5A: undetectable	3n5vA-4xj5A: 22.45 3n5vB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5V_B_H4BB760_1 (NITRIC OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.11A	3n5vA-4xj5A: undetectable 3n5vB-4xj5A: undetectable	3n5vA-4xj5A: 22.45 3n5vB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5Y_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.13A	3n5yA-4xj5A: undetectable 3n5yB-4xj5A: undetectable	3n5yA-4xj5A: 22.45 3n5yB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5Z_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.11A	3n5zA-4xj5A: undetectable 3n5zB-4xj5A: undetectable	3n5zA-4xj5A: 22.45 3n5zB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5Z_B_H4BB760_1 (NITRIC OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.17A	3n5zA-4xj5A: undetectable 3n5zB-4xj5A: undetectable	3n5zA-4xj5A: 22.45 3n5zB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLJ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.13A	3nljA-4xj5A: undetectable 3nljB-4xj5A: undetectable	3nljA-4xj5A: 20.61 3nljB-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLK_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	3nlkA-4xj5A: undetectable 3nlkB-4xj5A: undetectable	3nlkA-4xj5A: 22.25 3nlkB-4xj5A: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLN_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	3nlnA-4xj5A: undetectable 3nlnB-4xj5A: undetectable	3nlnA-4xj5A: 22.25 3nlnB-4xj5A: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLO_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.21A	3nloA-4xj5A: undetectable 3nloB-4xj5A: undetectable	3nloA-4xj5A: 22.25 3nloB-4xj5A: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLP_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	3nlpA-4xj5A: undetectable 3nlpB-4xj5A: undetectable	3nlpA-4xj5A: 20.61 3nlpB-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLQ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 8	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	3nlqA-4xj5A: undetectable 3nlqB-4xj5A: undetectable	3nlqA-4xj5A: 20.61 3nlqB-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLV_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	3nlvA-4xj5A: undetectable 3nlvB-4xj5A: undetectable	3nlvA-4xj5A: 22.45 3nlvB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLW_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	3nlwA-4xj5A: undetectable 3nlwB-4xj5A: undetectable	3nlwA-4xj5A: 22.45 3nlwB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLX_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	3nlxA-4xj5A: undetectable 3nlxB-4xj5A: undetectable	3nlxA-4xj5A: 22.45 3nlxB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q99_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.15A	3q99A-4xj5A: undetectable 3q99B-4xj5A: undetectable	3q99A-4xj5A: 22.45 3q99B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q9A_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.20A	3q9aA-4xj5A: undetectable 3q9aB-4xj5A: undetectable	3q9aA-4xj5A: 22.45 3q9aB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQJ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.20A	3rqjA-4xj5A: undetectable 3rqjB-4xj5A: undetectable	3rqjA-4xj5A: 22.45 3rqjB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQK_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	3rqkA-4xj5A: undetectable 3rqkB-4xj5A: undetectable	3rqkA-4xj5A: 22.45 3rqkB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SVP_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.12A	3svpA-4xj5A: undetectable 3svpB-4xj5A: undetectable	3svpA-4xj5A: 22.45 3svpB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFO_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.17A	3ufoA-4xj5A: undetectable 3ufoB-4xj5A: undetectable	3ufoA-4xj5A: 22.45 3ufoB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFS_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	3ufsA-4xj5A: undetectable 3ufsB-4xj5A: undetectable	3ufsA-4xj5A: 22.45 3ufsB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFU_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	3ufuA-4xj5A: undetectable 3ufuB-4xj5A: undetectable	3ufuA-4xj5A: 22.45 3ufuB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFV_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	3ufvA-4xj5A: undetectable 3ufvB-4xj5A: undetectable	3ufvA-4xj5A: 22.45 3ufvB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFV_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	3ufvA-4xj5A: undetectable 3ufvB-4xj5A: undetectable	3ufvA-4xj5A: 22.45 3ufvB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFW_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	3ufwA-4xj5A: undetectable 3ufwB-4xj5A: undetectable	3ufwA-4xj5A: 22.45 3ufwB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1478_0 (TRANSLATION ELONGATION FACTOR SELB)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	SER A 271 ASP A 270 ILE A 275 PHE A 268	None	0.99A	4acbC-4xj5A: undetectable	4acbC-4xj5A: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CAQ_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	4caqA-4xj5A: undetectable 4caqB-4xj5A: undetectable	4caqA-4xj5A: 22.45 4caqB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTQ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	4ctqA-4xj5A: undetectable 4ctqB-4xj5A: undetectable	4ctqA-4xj5A: 22.45 4ctqB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTR_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.13A	4ctrA-4xj5A: undetectable 4ctrB-4xj5A: undetectable	4ctrA-4xj5A: 22.45 4ctrB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTT_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	4cttA-4xj5A: undetectable 4cttB-4xj5A: undetectable	4cttA-4xj5A: 22.45 4cttB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX4_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	4cx4A-4xj5A: undetectable 4cx4B-4xj5A: undetectable	4cx4A-4xj5A: 20.61 4cx4B-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D2Y_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.16A	4d2yA-4xj5A: undetectable 4d2yB-4xj5A: undetectable	4d2yA-4xj5A: 22.45 4d2yB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D2Z_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.11A	4d2zA-4xj5A: undetectable 4d2zB-4xj5A: undetectable	4d2zA-4xj5A: 22.45 4d2zB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D30_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.14A	4d30A-4xj5A: undetectable 4d30B-4xj5A: undetectable	4d30A-4xj5A: 22.45 4d30B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D31_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.14A	4d31A-4xj5A: undetectable 4d31B-4xj5A: undetectable	4d31A-4xj5A: 22.45 4d31B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D31_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.15A	4d31A-4xj5A: undetectable 4d31B-4xj5A: undetectable	4d31A-4xj5A: 22.45 4d31B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEU_E_KANE301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	5 / 11	SER A 301 ASP A 291 ARG A 290 GLU A  28 GLU A 129	GH3  A1014 (-2.6A) None EDO  A1004 ( 4.2A) None None	1.46A	4feuB-4xj5A: 0.0 4feuE-4xj5A: 0.0	4feuB-4xj5A: 22.22 4feuE-4xj5A: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FW0_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	4fw0A-4xj5A: undetectable 4fw0B-4xj5A: undetectable	4fw0A-4xj5A: 22.45 4fw0B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSF_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.13A	4jsfA-4xj5A: undetectable 4jsfB-4xj5A: undetectable	4jsfA-4xj5A: 22.45 4jsfB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSG_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	4jsgA-4xj5A: undetectable 4jsgB-4xj5A: undetectable	4jsgA-4xj5A: 22.45 4jsgB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSH_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.11A	4jshA-4xj5A: undetectable 4jshB-4xj5A: undetectable	4jshA-4xj5A: 22.45 4jshB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSH_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.15A	4jshA-4xj5A: undetectable 4jshB-4xj5A: undetectable	4jshA-4xj5A: 22.45 4jshB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSI_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.12A	4jsiA-4xj5A: undetectable 4jsiB-4xj5A: undetectable	4jsiA-4xj5A: 22.45 4jsiB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5E_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	4k5eA-4xj5A: undetectable 4k5eB-4xj5A: undetectable	4k5eA-4xj5A: 22.45 4k5eB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCI_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.14A	4kciA-4xj5A: undetectable 4kciB-4xj5A: undetectable	4kciA-4xj5A: 22.45 4kciB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCI_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.14A	4kciA-4xj5A: undetectable 4kciB-4xj5A: undetectable	4kciA-4xj5A: 22.45 4kciB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCL_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.13A	4kclA-4xj5A: undetectable 4kclB-4xj5A: 1.9	4kclA-4xj5A: 22.45 4kclB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q5M_A_ROCA1101_3 (PROTEASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	3 / 3	ASP A 133 ASP A 131 ASN A 121	MG  A1001 ( 2.7A) MG  A1002 (-2.0A) None	0.84A	4q5mA-4xj5A: undetectable	4q5mA-4xj5A: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCH_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	4uchA-4xj5A: undetectable 4uchB-4xj5A: undetectable	4uchA-4xj5A: 22.31 4uchB-4xj5A: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UGZ_A_H4BA760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	4ugzA-4xj5A: undetectable 4ugzB-4xj5A: undetectable	4ugzA-4xj5A: 22.45 4ugzB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH0_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	4uh0A-4xj5A: undetectable 4uh0B-4xj5A: undetectable	4uh0A-4xj5A: 22.45 4uh0B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH0_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.16A	4uh0A-4xj5A: undetectable 4uh0B-4xj5A: undetectable	4uh0A-4xj5A: 22.45 4uh0B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH5_B_H4BB760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.14A	4uh5A-4xj5A: undetectable 4uh5B-4xj5A: undetectable	4uh5A-4xj5A: 22.63 4uh5B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPN_A_H4BA760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	4upnA-4xj5A: undetectable 4upnB-4xj5A: 1.9	4upnA-4xj5A: 22.45 4upnB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPP_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.17A	4uppA-4xj5A: undetectable 4uppB-4xj5A: undetectable	4uppA-4xj5A: 22.45 4uppB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3W_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.07A	4v3wA-4xj5A: 1.9 4v3wB-4xj5A: undetectable	4v3wA-4xj5A: 22.45 4v3wB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3X_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	4v3xA-4xj5A: undetectable 4v3xB-4xj5A: undetectable	4v3xA-4xj5A: 22.45 4v3xB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3X_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.19A	4v3xA-4xj5A: undetectable 4v3xB-4xj5A: undetectable	4v3xA-4xj5A: 22.45 4v3xB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3Y_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	4v3yA-4xj5A: undetectable 4v3yB-4xj5A: undetectable	4v3yA-4xj5A: 22.45 4v3yB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3Y_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 8	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.14A	4v3yA-4xj5A: undetectable 4v3yB-4xj5A: undetectable	4v3yA-4xj5A: 22.45 4v3yB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3Z_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	4v3zA-4xj5A: undetectable 4v3zB-4xj5A: undetectable	4v3zA-4xj5A: 22.45 4v3zB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3Z_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.19A	4v3zA-4xj5A: undetectable 4v3zB-4xj5A: undetectable	4v3zA-4xj5A: 22.45 4v3zB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XEY_A_1N1A601_2 (TYROSINE-PROTEIN KINASE ABL1)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	3 / 3	MET A  19 ASP A 118 PHE A 115	None EDO  A1008 (-3.7A) EDO  A1008 (-4.2A)	1.04A	4xeyA-4xj5A: undetectable	4xeyA-4xj5A: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XEY_B_1N1B601_2 (TYROSINE-PROTEIN KINASE ABL1)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	3 / 3	MET A  19 ASP A 118 PHE A 115	None EDO  A1008 (-3.7A) EDO  A1008 (-4.2A)	1.07A	4xeyB-4xj5A: undetectable	4xeyB-4xj5A: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD4_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.10A	5ad4A-4xj5A: undetectable 5ad4B-4xj5A: undetectable	5ad4A-4xj5A: 22.45 5ad4B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD4_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.15A	5ad4A-4xj5A: undetectable 5ad4B-4xj5A: undetectable	5ad4A-4xj5A: 22.45 5ad4B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD5_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	5ad5A-4xj5A: undetectable 5ad5B-4xj5A: undetectable	5ad5A-4xj5A: 22.45 5ad5B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD6_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.16A	5ad6A-4xj5A: undetectable 5ad6B-4xj5A: undetectable	5ad6A-4xj5A: 22.45 5ad6B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD7_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	5ad7A-4xj5A: 0.0 5ad7B-4xj5A: 0.0	5ad7A-4xj5A: 22.45 5ad7B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD7_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.15A	5ad7A-4xj5A: undetectable 5ad7B-4xj5A: undetectable	5ad7A-4xj5A: 22.45 5ad7B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD8_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	5ad8A-4xj5A: 0.0 5ad8B-4xj5A: 0.0	5ad8A-4xj5A: 22.45 5ad8B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD8_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	5ad8A-4xj5A: undetectable 5ad8B-4xj5A: undetectable	5ad8A-4xj5A: 22.45 5ad8B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADA_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	5adaA-4xj5A: undetectable 5adaB-4xj5A: undetectable	5adaA-4xj5A: 22.45 5adaB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADB_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.13A	5adbA-4xj5A: 0.0 5adbB-4xj5A: 0.0	5adbA-4xj5A: 22.45 5adbB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADC_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	5adcA-4xj5A: undetectable 5adcB-4xj5A: undetectable	5adcA-4xj5A: 22.45 5adcB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADD_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	5addA-4xj5A: undetectable 5addB-4xj5A: undetectable	5addA-4xj5A: 20.61 5addB-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADE_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.06A	5adeA-4xj5A: undetectable 5adeB-4xj5A: undetectable	5adeA-4xj5A: 20.61 5adeB-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGK_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.23A	5agkA-4xj5A: undetectable 5agkB-4xj5A: 1.9	5agkA-4xj5A: 22.45 5agkB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGO_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	5agoA-4xj5A: undetectable 5agoB-4xj5A: undetectable	5agoA-4xj5A: 22.45 5agoB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVP_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.08A	5fvpA-4xj5A: 2.1 5fvpB-4xj5A: undetectable	5fvpA-4xj5A: 22.45 5fvpB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVS_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	5fvsA-4xj5A: undetectable 5fvsB-4xj5A: undetectable	5fvsA-4xj5A: 22.45 5fvsB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVV_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	5fvvA-4xj5A: undetectable 5fvvB-4xj5A: 2.9	5fvvA-4xj5A: 22.63 5fvvB-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVW_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	5fvwA-4xj5A: undetectable 5fvwB-4xj5A: 2.9	5fvwA-4xj5A: 22.63 5fvwB-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVX_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.19A	5fvxA-4xj5A: undetectable 5fvxB-4xj5A: 2.1	5fvxA-4xj5A: 22.63 5fvxB-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FW0_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	5fw0A-4xj5A: undetectable 5fw0B-4xj5A: undetectable	5fw0A-4xj5A: 22.45 5fw0B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G0N_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	5g0nA-4xj5A: undetectable 5g0nB-4xj5A: undetectable	5g0nA-4xj5A: 20.61 5g0nB-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G0O_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	5g0oA-4xj5A: undetectable 5g0oB-4xj5A: undetectable	5g0oA-4xj5A: 20.61 5g0oB-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G0P_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	5g0pA-4xj5A: undetectable 5g0pB-4xj5A: undetectable	5g0pA-4xj5A: 20.61 5g0pB-4xj5A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	PHE A 337 CYH A 283 THR A 119 PHE A 268	None	1.42A	5mwyA-4xj5A: 3.1	5mwyA-4xj5A: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNR_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.21A	5unrA-4xj5A: 0.0 5unrB-4xj5A: 0.0	5unrA-4xj5A: 22.45 5unrB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNR_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	5unrA-4xj5A: undetectable 5unrB-4xj5A: undetectable	5unrA-4xj5A: 22.45 5unrB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNS_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.20A	5unsA-4xj5A: undetectable 5unsB-4xj5A: undetectable	5unsA-4xj5A: 22.45 5unsB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNS_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	5unsA-4xj5A: undetectable 5unsB-4xj5A: undetectable	5unsA-4xj5A: 22.45 5unsB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNT_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.14A	5untA-4xj5A: undetectable 5untB-4xj5A: undetectable	5untA-4xj5A: 22.45 5untB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNT_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.20A	5untA-4xj5A: undetectable 5untB-4xj5A: undetectable	5untA-4xj5A: 22.45 5untB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNU_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	5unuA-4xj5A: undetectable 5unuB-4xj5A: undetectable	5unuA-4xj5A: 22.45 5unuB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNU_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.21A	5unuA-4xj5A: undetectable 5unuB-4xj5A: undetectable	5unuA-4xj5A: 22.45 5unuB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNV_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.10A	5unvA-4xj5A: undetectable 5unvB-4xj5A: undetectable	5unvA-4xj5A: 22.45 5unvB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNV_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.10A	5unvA-4xj5A: undetectable 5unvB-4xj5A: undetectable	5unvA-4xj5A: 22.45 5unvB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNW_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	5unwA-4xj5A: 2.1 5unwB-4xj5A: undetectable	5unwA-4xj5A: 22.45 5unwB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNZ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 5	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	5unzA-4xj5A: 0.0 5unzB-4xj5A: 0.0	5unzA-4xj5A: 22.45 5unzB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNZ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.16A	5unzA-4xj5A: undetectable 5unzB-4xj5A: undetectable	5unzA-4xj5A: 22.45 5unzB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO0_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.14A	5uo0A-4xj5A: 2.1 5uo0B-4xj5A: undetectable	5uo0A-4xj5A: 22.45 5uo0B-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO2_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	5uo2A-4xj5A: undetectable 5uo2B-4xj5A: 2.2	5uo2A-4xj5A: 22.63 5uo2B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO3_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	5uo3A-4xj5A: undetectable 5uo3B-4xj5A: undetectable	5uo3A-4xj5A: 22.63 5uo3B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO3_B_H4BB803_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.16A	5uo3A-4xj5A: undetectable 5uo3B-4xj5A: undetectable	5uo3A-4xj5A: 22.63 5uo3B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO4_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.20A	5uo4A-4xj5A: undetectable 5uo4B-4xj5A: undetectable	5uo4A-4xj5A: 22.63 5uo4B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO6_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	5uo6A-4xj5A: undetectable 5uo6B-4xj5A: undetectable	5uo6A-4xj5A: 22.63 5uo6B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO7_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 8	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	5uo7A-4xj5A: undetectable 5uo7B-4xj5A: undetectable	5uo7A-4xj5A: 22.63 5uo7B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUI_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.12A	5vuiA-4xj5A: 2.1 5vuiB-4xj5A: undetectable	5vuiA-4xj5A: 22.45 5vuiB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUI_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.15A	5vuiA-4xj5A: 2.1 5vuiB-4xj5A: undetectable	5vuiA-4xj5A: 22.45 5vuiB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUJ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.05A	5vujA-4xj5A: undetectable 5vujB-4xj5A: undetectable	5vujA-4xj5A: 22.45 5vujB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUJ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.11A	5vujA-4xj5A: undetectable 5vujB-4xj5A: undetectable	5vujA-4xj5A: 22.45 5vujB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUK_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	5vukA-4xj5A: undetectable 5vukB-4xj5A: undetectable	5vukA-4xj5A: 22.45 5vukB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUM_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.14A	5vumA-4xj5A: undetectable 5vumB-4xj5A: undetectable	5vumA-4xj5A: 22.45 5vumB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUO_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	5vuoA-4xj5A: 1.9 5vuoB-4xj5A: undetectable	5vuoA-4xj5A: 22.45 5vuoB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUO_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.17A	5vuoA-4xj5A: 1.9 5vuoB-4xj5A: undetectable	5vuoA-4xj5A: 22.45 5vuoB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUP_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	5vupA-4xj5A: undetectable 5vupB-4xj5A: undetectable	5vupA-4xj5A: 22.45 5vupB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUQ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	5vuqA-4xj5A: undetectable 5vuqB-4xj5A: undetectable	5vuqA-4xj5A: 22.45 5vuqB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUQ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.16A	5vuqA-4xj5A: undetectable 5vuqB-4xj5A: undetectable	5vuqA-4xj5A: 22.45 5vuqB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUR_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.21A	5vurA-4xj5A: undetectable 5vurB-4xj5A: 1.9	5vurA-4xj5A: 22.45 5vurB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUS_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.21A	5vusA-4xj5A: 2.0 5vusB-4xj5A: undetectable	5vusA-4xj5A: 22.45 5vusB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUS_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.15A	5vusA-4xj5A: 2.0 5vusB-4xj5A: undetectable	5vusA-4xj5A: 22.45 5vusB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUT_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	5vutA-4xj5A: undetectable 5vutB-4xj5A: undetectable	5vutA-4xj5A: 22.45 5vutB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUT_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.16A	5vutA-4xj5A: undetectable 5vutB-4xj5A: undetectable	5vutA-4xj5A: 22.45 5vutB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUU_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.16A	5vuuA-4xj5A: undetectable 5vuuB-4xj5A: undetectable	5vuuA-4xj5A: 22.45 5vuuB-4xj5A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUX_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	5vuxA-4xj5A: undetectable 5vuxB-4xj5A: undetectable	5vuxA-4xj5A: 22.63 5vuxB-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV2_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	5vv2A-4xj5A: undetectable 5vv2B-4xj5A: 1.9	5vv2A-4xj5A: 22.63 5vv2B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV5_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.12A	5vv5A-4xj5A: undetectable 5vv5B-4xj5A: 1.9	5vv5A-4xj5A: 22.63 5vv5B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV5_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.20A	5vv5A-4xj5A: undetectable 5vv5B-4xj5A: 1.9	5vv5A-4xj5A: 22.63 5vv5B-4xj5A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUQ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 6	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.11A	6auqA-4xj5A: undetectable 6auqB-4xj5A: undetectable	6auqA-4xj5A: 12.08 6auqB-4xj5A: 12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUT_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	6autA-4xj5A: undetectable 6autB-4xj5A: undetectable	6autA-4xj5A: 12.08 6autB-4xj5A: 12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUT_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.21A	6autA-4xj5A: undetectable 6autB-4xj5A: undetectable	6autA-4xj5A: 12.08 6autB-4xj5A: 12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUV_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	6auvA-4xj5A: undetectable 6auvB-4xj5A: undetectable	6auvA-4xj5A: 12.08 6auvB-4xj5A: 12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUV_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.19A	6auvA-4xj5A: undetectable 6auvB-4xj5A: undetectable	6auvA-4xj5A: 12.08 6auvB-4xj5A: 12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUW_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	6auwA-4xj5A: undetectable 6auwB-4xj5A: undetectable	6auwA-4xj5A: 12.08 6auwB-4xj5A: 12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUX_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.20A	6auxA-4xj5A: undetectable 6auxB-4xj5A: undetectable	6auxA-4xj5A: 12.08 6auxB-4xj5A: 12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUX_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.19A	6auxA-4xj5A: undetectable 6auxB-4xj5A: undetectable	6auxA-4xj5A: 12.08 6auxB-4xj5A: 12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUZ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	6auzA-4xj5A: undetectable 6auzB-4xj5A: 2.9	6auzA-4xj5A: 12.60 6auzB-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUZ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	6auzA-4xj5A: undetectable 6auzB-4xj5A: 2.9	6auzA-4xj5A: 12.60 6auzB-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV1_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	6av1A-4xj5A: undetectable 6av1B-4xj5A: undetectable	6av1A-4xj5A: 12.60 6av1B-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV2_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.19A	6av2A-4xj5A: undetectable 6av2B-4xj5A: undetectable	6av2A-4xj5A: 12.60 6av2B-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV3_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.15A	6av3A-4xj5A: undetectable 6av3B-4xj5A: 2.0	6av3A-4xj5A: 12.60 6av3B-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV3_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.17A	6av3A-4xj5A: undetectable 6av3B-4xj5A: 2.0	6av3A-4xj5A: 12.60 6av3B-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV4_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.18A	6av4A-4xj5A: undetectable 6av4B-4xj5A: undetectable	6av4A-4xj5A: 12.60 6av4B-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV4_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.18A	6av4A-4xj5A: undetectable 6av4B-4xj5A: undetectable	6av4A-4xj5A: 12.60 6av4B-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV5_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	ARG A 280 VAL A 309 TRP A 267 PHE A 268	None	1.17A	6av5A-4xj5A: undetectable 6av5B-4xj5A: undetectable	6av5A-4xj5A: 12.60 6av5B-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV5_B_H4BB803_1 (NITRIC OXIDE SYNTHASE, BRAIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 7	TRP A 267 PHE A 268 ARG A 280 VAL A 309	None	1.16A	6av5A-4xj5A: undetectable 6av5B-4xj5A: undetectable	6av5A-4xj5A: 12.60 6av5B-4xj5A: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6D8P_B_ACTB804_0 (UNCHARACTERIZED PROTEIN)	4xj5	CYCLIC AMP-GMP SYNTHASE (Vibrio cholerae)	4 / 4	HIS A 317 VAL A 282 LEU A 312 ALA A 319	EDO  A1012 (-4.0A) None None EDO  A1012 (-3.3A)	1.30A	6d8pB-4xj5A: undetectable	6d8pB-4xj5A: 19.75