SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xj6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 1k2rA-4xj6A:
undetectable
1k2rB-4xj6A:
undetectable		 1k2rA-4xj6A:
21.03
1k2rB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 1k2rA-4xj6A:
undetectable
1k2rB-4xj6A:
undetectable		 1k2rA-4xj6A:
21.03
1k2rB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 1k2rA-4xj6A:
undetectable
1k2rB-4xj6A:
undetectable		 1k2rA-4xj6A:
21.03
1k2rB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 1k2rA-4xj6A:
undetectable
1k2rB-4xj6A:
undetectable		 1k2rA-4xj6A:
21.03
1k2rB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.21A 1k2sA-4xj6A:
undetectable
1k2sB-4xj6A:
undetectable		 1k2sA-4xj6A:
21.03
1k2sB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.13A 1k2sA-4xj6A:
undetectable
1k2sB-4xj6A:
undetectable		 1k2sA-4xj6A:
21.03
1k2sB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 1k2sA-4xj6A:
undetectable
1k2sB-4xj6A:
undetectable		 1k2sA-4xj6A:
21.03
1k2sB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 1k2sA-4xj6A:
undetectable
1k2sB-4xj6A:
undetectable		 1k2sA-4xj6A:
21.03
1k2sB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 1k2tA-4xj6A:
undetectable
1k2tB-4xj6A:
undetectable		 1k2tA-4xj6A:
21.03
1k2tB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 1k2tA-4xj6A:
undetectable
1k2tB-4xj6A:
undetectable		 1k2tA-4xj6A:
21.03
1k2tB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.22A 1k2tA-4xj6A:
undetectable
1k2tB-4xj6A:
undetectable		 1k2tA-4xj6A:
21.03
1k2tB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 1k2tA-4xj6A:
undetectable
1k2tB-4xj6A:
undetectable		 1k2tA-4xj6A:
21.03
1k2tB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.18A 1k2uA-4xj6A:
undetectable
1k2uB-4xj6A:
undetectable		 1k2uA-4xj6A:
21.03
1k2uB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.13A 1k2uA-4xj6A:
undetectable
1k2uB-4xj6A:
undetectable		 1k2uA-4xj6A:
21.03
1k2uB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.22A 1k2uA-4xj6A:
undetectable
1k2uB-4xj6A:
undetectable		 1k2uA-4xj6A:
21.03
1k2uB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 1k2uA-4xj6A:
undetectable
1k2uB-4xj6A:
undetectable		 1k2uA-4xj6A:
21.03
1k2uB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 1lzxA-4xj6A:
undetectable
1lzxB-4xj6A:
undetectable		 1lzxA-4xj6A:
21.03
1lzxB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 1lzxA-4xj6A:
undetectable
1lzxB-4xj6A:
undetectable		 1lzxA-4xj6A:
21.03
1lzxB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 1lzxA-4xj6A:
undetectable
1lzxB-4xj6A:
undetectable		 1lzxA-4xj6A:
21.03
1lzxB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 1lzxA-4xj6A:
undetectable
1lzxB-4xj6A:
undetectable		 1lzxA-4xj6A:
21.03
1lzxB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 1lzzA-4xj6A:
undetectable
1lzzB-4xj6A:
undetectable		 1lzzA-4xj6A:
21.03
1lzzB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 1lzzA-4xj6A:
undetectable
1lzzB-4xj6A:
undetectable		 1lzzA-4xj6A:
21.03
1lzzB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 1lzzA-4xj6A:
undetectable
1lzzB-4xj6A:
undetectable		 1lzzA-4xj6A:
21.03
1lzzB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 1lzzA-4xj6A:
undetectable
1lzzB-4xj6A:
undetectable		 1lzzA-4xj6A:
21.03
1lzzB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 1m00A-4xj6A:
0.0
1m00B-4xj6A:
undetectable		 1m00A-4xj6A:
21.03
1m00B-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 1m00A-4xj6A:
0.0
1m00B-4xj6A:
undetectable		 1m00A-4xj6A:
21.03
1m00B-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 1m00A-4xj6A:
0.0
1m00B-4xj6A:
undetectable		 1m00A-4xj6A:
21.03
1m00B-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 1m00A-4xj6A:
0.0
1m00B-4xj6A:
undetectable		 1m00A-4xj6A:
21.03
1m00B-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 1mmvA-4xj6A:
undetectable
1mmvB-4xj6A:
undetectable		 1mmvA-4xj6A:
21.03
1mmvB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 1mmvA-4xj6A:
undetectable
1mmvB-4xj6A:
undetectable		 1mmvA-4xj6A:
21.03
1mmvB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 1mmvA-4xj6A:
undetectable
1mmvB-4xj6A:
undetectable		 1mmvA-4xj6A:
21.03
1mmvB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 1mmvA-4xj6A:
undetectable
1mmvB-4xj6A:
undetectable		 1mmvA-4xj6A:
21.03
1mmvB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 1mmwA-4xj6A:
undetectable
1mmwB-4xj6A:
undetectable		 1mmwA-4xj6A:
21.03
1mmwB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 1mmwA-4xj6A:
undetectable
1mmwB-4xj6A:
undetectable		 1mmwA-4xj6A:
21.03
1mmwB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 1mmwA-4xj6A:
undetectable
1mmwB-4xj6A:
undetectable		 1mmwA-4xj6A:
21.03
1mmwB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 1mmwA-4xj6A:
undetectable
1mmwB-4xj6A:
undetectable		 1mmwA-4xj6A:
21.03
1mmwB-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 12 THR A  72
VAL A  74
LEU A  69
LEU A  85
LEU A 152
 None
 1.00A 1mx1C-4xj6A:
undetectable		 1mx1C-4xj6A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
ILE A 271
 None
 1.26A 1nsiA-4xj6A:
undetectable
1nsiB-4xj6A:
undetectable		 1nsiA-4xj6A:
22.82
1nsiB-4xj6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
ILE A 271
PHE A 264
GLU A 266
 None
 1.28A 1nsiC-4xj6A:
undetectable
1nsiD-4xj6A:
undetectable		 1nsiC-4xj6A:
22.82
1nsiD-4xj6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
ILE A 271
 None
 1.30A 1nsiC-4xj6A:
undetectable
1nsiD-4xj6A:
undetectable		 1nsiC-4xj6A:
22.82
1nsiD-4xj6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 1om4A-4xj6A:
undetectable
1om4B-4xj6A:
undetectable		 1om4A-4xj6A:
21.06
1om4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 1om4A-4xj6A:
undetectable
1om4B-4xj6A:
undetectable		 1om4A-4xj6A:
21.06
1om4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 1om4A-4xj6A:
undetectable
1om4B-4xj6A:
undetectable		 1om4A-4xj6A:
21.06
1om4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 1om4A-4xj6A:
undetectable
1om4B-4xj6A:
undetectable		 1om4A-4xj6A:
21.06
1om4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.20A 1om5A-4xj6A:
undetectable
1om5B-4xj6A:
undetectable		 1om5A-4xj6A:
21.11
1om5B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.17A 1om5A-4xj6A:
undetectable
1om5B-4xj6A:
undetectable		 1om5A-4xj6A:
21.11
1om5B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.29A 1om5A-4xj6A:
undetectable
1om5B-4xj6A:
undetectable		 1om5A-4xj6A:
21.11
1om5B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 1om5A-4xj6A:
undetectable
1om5B-4xj6A:
undetectable		 1om5A-4xj6A:
21.11
1om5B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 1p6hA-4xj6A:
undetectable
1p6hB-4xj6A:
undetectable		 1p6hA-4xj6A:
21.11
1p6hB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 1p6hA-4xj6A:
undetectable
1p6hB-4xj6A:
undetectable		 1p6hA-4xj6A:
21.11
1p6hB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 1p6hA-4xj6A:
undetectable
1p6hB-4xj6A:
undetectable		 1p6hA-4xj6A:
21.11
1p6hB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 1p6hA-4xj6A:
undetectable
1p6hB-4xj6A:
undetectable		 1p6hA-4xj6A:
21.11
1p6hB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 1p6iA-4xj6A:
undetectable
1p6iB-4xj6A:
1.7		 1p6iA-4xj6A:
21.11
1p6iB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 1p6iA-4xj6A:
undetectable
1p6iB-4xj6A:
1.7		 1p6iA-4xj6A:
21.11
1p6iB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.22A 1p6iA-4xj6A:
undetectable
1p6iB-4xj6A:
1.7		 1p6iA-4xj6A:
21.11
1p6iB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 1p6iA-4xj6A:
undetectable
1p6iB-4xj6A:
1.7		 1p6iA-4xj6A:
21.11
1p6iB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 1p6jA-4xj6A:
undetectable
1p6jB-4xj6A:
undetectable		 1p6jA-4xj6A:
21.11
1p6jB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 1p6jA-4xj6A:
undetectable
1p6jB-4xj6A:
undetectable		 1p6jA-4xj6A:
21.11
1p6jB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 1p6jA-4xj6A:
undetectable
1p6jB-4xj6A:
undetectable		 1p6jA-4xj6A:
21.11
1p6jB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 1p6jA-4xj6A:
undetectable
1p6jB-4xj6A:
undetectable		 1p6jA-4xj6A:
21.11
1p6jB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 1p6kA-4xj6A:
undetectable
1p6kB-4xj6A:
undetectable		 1p6kA-4xj6A:
21.11
1p6kB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 1p6kA-4xj6A:
undetectable
1p6kB-4xj6A:
undetectable		 1p6kA-4xj6A:
21.11
1p6kB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 1p6kA-4xj6A:
undetectable
1p6kB-4xj6A:
undetectable		 1p6kA-4xj6A:
21.11
1p6kB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 1p6kA-4xj6A:
undetectable
1p6kB-4xj6A:
undetectable		 1p6kA-4xj6A:
21.11
1p6kB-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.18A 1rs6A-4xj6A:
undetectable
1rs6B-4xj6A:
2.1		 1rs6A-4xj6A:
21.11
1rs6B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 1rs6A-4xj6A:
undetectable
1rs6B-4xj6A:
2.1		 1rs6A-4xj6A:
21.11
1rs6B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 1rs6A-4xj6A:
undetectable
1rs6B-4xj6A:
undetectable		 1rs6A-4xj6A:
21.11
1rs6B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 1rs6A-4xj6A:
undetectable
1rs6B-4xj6A:
undetectable		 1rs6A-4xj6A:
21.11
1rs6B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.16A 1rs7A-4xj6A:
undetectable
1rs7B-4xj6A:
undetectable		 1rs7A-4xj6A:
21.11
1rs7B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 1rs7A-4xj6A:
undetectable
1rs7B-4xj6A:
undetectable		 1rs7A-4xj6A:
21.11
1rs7B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 1rs7A-4xj6A:
undetectable
1rs7B-4xj6A:
undetectable		 1rs7A-4xj6A:
21.11
1rs7B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 1rs7A-4xj6A:
undetectable
1rs7B-4xj6A:
undetectable		 1rs7A-4xj6A:
21.11
1rs7B-4xj6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		3 / 3 PRO A 257
ASP A 341
ASP A 262
 GH3  A 504 ( 4.1A)
None
None
 0.52A 1sqfA-4xj6A:
undetectable		 1sqfA-4xj6A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 1zvlA-4xj6A:
undetectable
1zvlB-4xj6A:
undetectable		 1zvlA-4xj6A:
20.58
1zvlB-4xj6A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.24A 1zvlA-4xj6A:
undetectable
1zvlB-4xj6A:
1.6		 1zvlA-4xj6A:
20.58
1zvlB-4xj6A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 1zvlA-4xj6A:
undetectable
1zvlB-4xj6A:
1.6		 1zvlA-4xj6A:
20.58
1zvlB-4xj6A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 1zzqA-4xj6A:
undetectable
1zzqB-4xj6A:
undetectable		 1zzqA-4xj6A:
20.99
1zzqB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 1zzqA-4xj6A:
undetectable
1zzqB-4xj6A:
undetectable		 1zzqA-4xj6A:
20.99
1zzqB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 1zzqA-4xj6A:
undetectable
1zzqB-4xj6A:
undetectable		 1zzqA-4xj6A:
20.99
1zzqB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 1zzqA-4xj6A:
undetectable
1zzqB-4xj6A:
undetectable		 1zzqA-4xj6A:
20.99
1zzqB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 1zzrA-4xj6A:
undetectable
1zzrB-4xj6A:
undetectable		 1zzrA-4xj6A:
20.99
1zzrB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 1zzrA-4xj6A:
undetectable
1zzrB-4xj6A:
undetectable		 1zzrA-4xj6A:
20.99
1zzrB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 1zzrA-4xj6A:
undetectable
1zzrB-4xj6A:
undetectable		 1zzrA-4xj6A:
20.99
1zzrB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 1zzrA-4xj6A:
undetectable
1zzrB-4xj6A:
undetectable		 1zzrA-4xj6A:
20.99
1zzrB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 1zzuA-4xj6A:
undetectable
1zzuB-4xj6A:
2.0		 1zzuA-4xj6A:
20.99
1zzuB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 1zzuA-4xj6A:
undetectable
1zzuB-4xj6A:
2.0		 1zzuA-4xj6A:
20.99
1zzuB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.11A 1zzuA-4xj6A:
undetectable
1zzuB-4xj6A:
2.0		 1zzuA-4xj6A:
20.99
1zzuB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 1zzuA-4xj6A:
undetectable
1zzuB-4xj6A:
2.0		 1zzuA-4xj6A:
20.99
1zzuB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 2g6hA-4xj6A:
undetectable
2g6hB-4xj6A:
undetectable		 2g6hA-4xj6A:
20.99
2g6hB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 2g6hA-4xj6A:
undetectable
2g6hB-4xj6A:
undetectable		 2g6hA-4xj6A:
20.99
2g6hB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 2g6hA-4xj6A:
undetectable
2g6hB-4xj6A:
undetectable		 2g6hA-4xj6A:
20.99
2g6hB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 2g6hA-4xj6A:
undetectable
2g6hB-4xj6A:
undetectable		 2g6hA-4xj6A:
20.99
2g6hB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 2g6kA-4xj6A:
undetectable
2g6kB-4xj6A:
undetectable		 2g6kA-4xj6A:
20.99
2g6kB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 2g6kA-4xj6A:
undetectable
2g6kB-4xj6A:
undetectable		 2g6kA-4xj6A:
20.99
2g6kB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 2g6kA-4xj6A:
undetectable
2g6kB-4xj6A:
undetectable		 2g6kA-4xj6A:
20.99
2g6kB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 2g6kA-4xj6A:
undetectable
2g6kB-4xj6A:
undetectable		 2g6kA-4xj6A:
20.99
2g6kB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 2g6mA-4xj6A:
undetectable
2g6mB-4xj6A:
undetectable		 2g6mA-4xj6A:
20.99
2g6mB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 2g6mA-4xj6A:
undetectable
2g6mB-4xj6A:
undetectable		 2g6mA-4xj6A:
20.99
2g6mB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 2g6mA-4xj6A:
undetectable
2g6mB-4xj6A:
undetectable		 2g6mA-4xj6A:
20.99
2g6mB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 2g6mA-4xj6A:
undetectable
2g6mB-4xj6A:
undetectable		 2g6mA-4xj6A:
20.99
2g6mB-4xj6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 2hx3A-4xj6A:
undetectable
2hx3B-4xj6A:
undetectable		 2hx3A-4xj6A:
21.06
2hx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 2hx3A-4xj6A:
undetectable
2hx3B-4xj6A:
undetectable		 2hx3A-4xj6A:
21.06
2hx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 2hx3A-4xj6A:
undetectable
2hx3B-4xj6A:
undetectable		 2hx3A-4xj6A:
21.06
2hx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 2hx3A-4xj6A:
undetectable
2hx3B-4xj6A:
undetectable		 2hx3A-4xj6A:
21.06
2hx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 2hx4A-4xj6A:
undetectable
2hx4B-4xj6A:
undetectable		 2hx4A-4xj6A:
21.06
2hx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 2hx4A-4xj6A:
undetectable
2hx4B-4xj6A:
undetectable		 2hx4A-4xj6A:
21.06
2hx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 2hx4A-4xj6A:
undetectable
2hx4B-4xj6A:
undetectable		 2hx4A-4xj6A:
21.06
2hx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 2hx4A-4xj6A:
undetectable
2hx4B-4xj6A:
undetectable		 2hx4A-4xj6A:
21.06
2hx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
ILE A 271
 None
 1.25A 2nsiC-4xj6A:
undetectable
2nsiD-4xj6A:
undetectable		 2nsiC-4xj6A:
22.82
2nsiD-4xj6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 12 ALA A 303
LEU A 300
LEU A 329
LEU A 328
PRO A 295
 None
 0.88A 2qxsA-4xj6A:
2.6		 2qxsA-4xj6A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 12 ALA A 303
LEU A 300
LEU A 329
LEU A 328
PRO A 295
 None
 0.91A 2qxsB-4xj6A:
undetectable		 2qxsB-4xj6A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3b3mA-4xj6A:
undetectable
3b3mB-4xj6A:
undetectable		 3b3mA-4xj6A:
21.06
3b3mB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3b3mA-4xj6A:
undetectable
3b3mB-4xj6A:
undetectable		 3b3mA-4xj6A:
21.06
3b3mB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 3b3mA-4xj6A:
undetectable
3b3mB-4xj6A:
undetectable		 3b3mA-4xj6A:
21.06
3b3mB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3b3mA-4xj6A:
undetectable
3b3mB-4xj6A:
undetectable		 3b3mA-4xj6A:
21.06
3b3mB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3b3nA-4xj6A:
undetectable
3b3nB-4xj6A:
undetectable		 3b3nA-4xj6A:
21.06
3b3nB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.05A 3b3nA-4xj6A:
undetectable
3b3nB-4xj6A:
undetectable		 3b3nA-4xj6A:
21.06
3b3nB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 3b3nA-4xj6A:
undetectable
3b3nB-4xj6A:
undetectable		 3b3nA-4xj6A:
21.06
3b3nB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3b3nA-4xj6A:
undetectable
3b3nB-4xj6A:
undetectable		 3b3nA-4xj6A:
21.06
3b3nB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3b3oA-4xj6A:
undetectable
3b3oB-4xj6A:
undetectable		 3b3oA-4xj6A:
21.06
3b3oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3b3oA-4xj6A:
undetectable
3b3oB-4xj6A:
undetectable		 3b3oA-4xj6A:
21.06
3b3oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 3b3oA-4xj6A:
undetectable
3b3oB-4xj6A:
undetectable		 3b3oA-4xj6A:
21.06
3b3oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3b3oA-4xj6A:
undetectable
3b3oB-4xj6A:
undetectable		 3b3oA-4xj6A:
21.06
3b3oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.19A 3b3pA-4xj6A:
undetectable
3b3pB-4xj6A:
undetectable		 3b3pA-4xj6A:
21.06
3b3pB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3b3pA-4xj6A:
undetectable
3b3pB-4xj6A:
undetectable		 3b3pA-4xj6A:
21.06
3b3pB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.22A 3b3pA-4xj6A:
undetectable
3b3pB-4xj6A:
undetectable		 3b3pA-4xj6A:
21.06
3b3pB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 3b3pA-4xj6A:
undetectable
3b3pB-4xj6A:
undetectable		 3b3pA-4xj6A:
21.06
3b3pB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 12 PHE A 100
ALA A 196
ALA A  96
THR A  41
THR A 134
 None
 1.25A 3dl9B-4xj6A:
undetectable		 3dl9B-4xj6A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3dqrA-4xj6A:
undetectable
3dqrB-4xj6A:
undetectable		 3dqrA-4xj6A:
21.06
3dqrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3dqrA-4xj6A:
undetectable
3dqrB-4xj6A:
undetectable		 3dqrA-4xj6A:
21.06
3dqrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3dqrA-4xj6A:
undetectable
3dqrB-4xj6A:
undetectable		 3dqrA-4xj6A:
21.06
3dqrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3dqrA-4xj6A:
undetectable
3dqrB-4xj6A:
undetectable		 3dqrA-4xj6A:
21.06
3dqrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
ILE A 271
PHE A 264
GLU A 266
 None
 1.22A 3e7gA-4xj6A:
undetectable
3e7gB-4xj6A:
undetectable		 3e7gA-4xj6A:
22.95
3e7gB-4xj6A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
ILE A 271
 None
 1.23A 3e7gA-4xj6A:
undetectable
3e7gB-4xj6A:
undetectable		 3e7gA-4xj6A:
22.95
3e7gB-4xj6A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
ILE A 271
PHE A 264
GLU A 266
 None
 1.23A 3e7gC-4xj6A:
undetectable
3e7gD-4xj6A:
undetectable		 3e7gC-4xj6A:
22.95
3e7gD-4xj6A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
ILE A 271
 None
 1.24A 3e7gC-4xj6A:
undetectable
3e7gD-4xj6A:
undetectable		 3e7gC-4xj6A:
22.95
3e7gD-4xj6A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 3fc5A-4xj6A:
undetectable
3fc5B-4xj6A:
undetectable		 3fc5A-4xj6A:
21.06
3fc5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 3fc5A-4xj6A:
undetectable
3fc5B-4xj6A:
undetectable		 3fc5A-4xj6A:
21.06
3fc5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3fc5A-4xj6A:
undetectable
3fc5B-4xj6A:
undetectable		 3fc5A-4xj6A:
21.06
3fc5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 3fc5A-4xj6A:
undetectable
3fc5B-4xj6A:
undetectable		 3fc5A-4xj6A:
21.06
3fc5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 3hsnA-4xj6A:
undetectable
3hsnB-4xj6A:
undetectable		 3hsnA-4xj6A:
21.06
3hsnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 3hsnA-4xj6A:
undetectable
3hsnB-4xj6A:
undetectable		 3hsnA-4xj6A:
21.06
3hsnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 3hsnA-4xj6A:
undetectable
3hsnB-4xj6A:
undetectable		 3hsnA-4xj6A:
21.06
3hsnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.04A 3hsnA-4xj6A:
undetectable
3hsnB-4xj6A:
undetectable		 3hsnA-4xj6A:
21.06
3hsnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3hsoA-4xj6A:
undetectable
3hsoB-4xj6A:
undetectable		 3hsoA-4xj6A:
21.06
3hsoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 3hsoA-4xj6A:
undetectable
3hsoB-4xj6A:
undetectable		 3hsoA-4xj6A:
21.06
3hsoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3hsoA-4xj6A:
undetectable
3hsoB-4xj6A:
undetectable		 3hsoA-4xj6A:
21.06
3hsoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.06A 3hsoA-4xj6A:
undetectable
3hsoB-4xj6A:
undetectable		 3hsoA-4xj6A:
21.06
3hsoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 3hspA-4xj6A:
undetectable
3hspB-4xj6A:
undetectable		 3hspA-4xj6A:
21.06
3hspB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 3hspA-4xj6A:
undetectable
3hspB-4xj6A:
undetectable		 3hspA-4xj6A:
21.06
3hspB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3hspA-4xj6A:
undetectable
3hspB-4xj6A:
undetectable		 3hspA-4xj6A:
21.06
3hspB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 3hspA-4xj6A:
undetectable
3hspB-4xj6A:
undetectable		 3hspA-4xj6A:
21.06
3hspB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3jt3A-4xj6A:
undetectable
3jt3B-4xj6A:
undetectable		 3jt3A-4xj6A:
21.06
3jt3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3jt3A-4xj6A:
undetectable
3jt3B-4xj6A:
undetectable		 3jt3A-4xj6A:
21.06
3jt3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 3jt3A-4xj6A:
undetectable
3jt3B-4xj6A:
undetectable		 3jt3A-4xj6A:
21.06
3jt3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 3jt3A-4xj6A:
undetectable
3jt3B-4xj6A:
undetectable		 3jt3A-4xj6A:
21.06
3jt3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 3jt4A-4xj6A:
undetectable
3jt4B-4xj6A:
undetectable		 3jt4A-4xj6A:
21.06
3jt4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3jt4A-4xj6A:
undetectable
3jt4B-4xj6A:
undetectable		 3jt4A-4xj6A:
21.06
3jt4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.10A 3jt4A-4xj6A:
undetectable
3jt4B-4xj6A:
undetectable		 3jt4A-4xj6A:
21.06
3jt4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3jt4A-4xj6A:
undetectable
3jt4B-4xj6A:
undetectable		 3jt4A-4xj6A:
21.06
3jt4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 3jt5A-4xj6A:
undetectable
3jt5B-4xj6A:
undetectable		 3jt5A-4xj6A:
21.06
3jt5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3jt5A-4xj6A:
undetectable
3jt5B-4xj6A:
undetectable		 3jt5A-4xj6A:
21.06
3jt5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3jt5A-4xj6A:
undetectable
3jt5B-4xj6A:
undetectable		 3jt5A-4xj6A:
21.06
3jt5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 3jt5A-4xj6A:
undetectable
3jt5B-4xj6A:
undetectable		 3jt5A-4xj6A:
21.06
3jt5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 3jt6A-4xj6A:
undetectable
3jt6B-4xj6A:
undetectable		 3jt6A-4xj6A:
21.06
3jt6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3jt6A-4xj6A:
undetectable
3jt6B-4xj6A:
undetectable		 3jt6A-4xj6A:
21.06
3jt6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3jt6A-4xj6A:
undetectable
3jt6B-4xj6A:
undetectable		 3jt6A-4xj6A:
21.06
3jt6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3jt6A-4xj6A:
undetectable
3jt6B-4xj6A:
undetectable		 3jt6A-4xj6A:
21.06
3jt6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 3jt7A-4xj6A:
undetectable
3jt7B-4xj6A:
undetectable		 3jt7A-4xj6A:
21.06
3jt7B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3jt7A-4xj6A:
undetectable
3jt7B-4xj6A:
undetectable		 3jt7A-4xj6A:
21.06
3jt7B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3jt7A-4xj6A:
undetectable
3jt7B-4xj6A:
undetectable		 3jt7A-4xj6A:
21.06
3jt7B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 3jt7A-4xj6A:
undetectable
3jt7B-4xj6A:
undetectable		 3jt7A-4xj6A:
21.06
3jt7B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 3jt8A-4xj6A:
undetectable
3jt8B-4xj6A:
undetectable		 3jt8A-4xj6A:
21.06
3jt8B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3jt8A-4xj6A:
undetectable
3jt8B-4xj6A:
undetectable		 3jt8A-4xj6A:
21.06
3jt8B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 3jt8A-4xj6A:
undetectable
3jt8B-4xj6A:
undetectable		 3jt8A-4xj6A:
21.06
3jt8B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3jt8A-4xj6A:
undetectable
3jt8B-4xj6A:
undetectable		 3jt8A-4xj6A:
21.06
3jt8B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3jt9A-4xj6A:
undetectable
3jt9B-4xj6A:
undetectable		 3jt9A-4xj6A:
21.06
3jt9B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 3jt9A-4xj6A:
undetectable
3jt9B-4xj6A:
undetectable		 3jt9A-4xj6A:
21.06
3jt9B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 3jt9A-4xj6A:
undetectable
3jt9B-4xj6A:
undetectable		 3jt9A-4xj6A:
21.06
3jt9B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 3jt9A-4xj6A:
undetectable
3jt9B-4xj6A:
undetectable		 3jt9A-4xj6A:
21.06
3jt9B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.16A 3jtaA-4xj6A:
undetectable
3jtaB-4xj6A:
undetectable		 3jtaA-4xj6A:
21.06
3jtaB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3jtaA-4xj6A:
undetectable
3jtaB-4xj6A:
undetectable		 3jtaA-4xj6A:
21.06
3jtaB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3jtaA-4xj6A:
undetectable
3jtaB-4xj6A:
undetectable		 3jtaA-4xj6A:
21.06
3jtaB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 3jtaA-4xj6A:
undetectable
3jtaB-4xj6A:
undetectable		 3jtaA-4xj6A:
21.06
3jtaB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 3jwsA-4xj6A:
0.0
3jwsB-4xj6A:
undetectable		 3jwsA-4xj6A:
20.85
3jwsB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3jwsA-4xj6A:
0.0
3jwsB-4xj6A:
undetectable		 3jwsA-4xj6A:
20.85
3jwsB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 3jwsA-4xj6A:
0.0
3jwsB-4xj6A:
undetectable		 3jwsA-4xj6A:
20.85
3jwsB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 3jwsA-4xj6A:
0.0
3jwsB-4xj6A:
undetectable		 3jwsA-4xj6A:
20.85
3jwsB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3jwtA-4xj6A:
undetectable
3jwtB-4xj6A:
undetectable		 3jwtA-4xj6A:
20.85
3jwtB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3jwtA-4xj6A:
undetectable
3jwtB-4xj6A:
undetectable		 3jwtA-4xj6A:
20.85
3jwtB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3jwtA-4xj6A:
undetectable
3jwtB-4xj6A:
undetectable		 3jwtA-4xj6A:
20.85
3jwtB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3jwtA-4xj6A:
undetectable
3jwtB-4xj6A:
undetectable		 3jwtA-4xj6A:
20.85
3jwtB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 3jwuA-4xj6A:
undetectable
3jwuB-4xj6A:
2.0		 3jwuA-4xj6A:
20.85
3jwuB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3jwuA-4xj6A:
undetectable
3jwuB-4xj6A:
2.0		 3jwuA-4xj6A:
20.85
3jwuB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3jwuA-4xj6A:
undetectable
3jwuB-4xj6A:
2.0		 3jwuA-4xj6A:
20.85
3jwuB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 3jwuA-4xj6A:
undetectable
3jwuB-4xj6A:
2.0		 3jwuA-4xj6A:
20.85
3jwuB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 3jwvA-4xj6A:
undetectable
3jwvB-4xj6A:
undetectable		 3jwvA-4xj6A:
20.85
3jwvB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3jwvA-4xj6A:
undetectable
3jwvB-4xj6A:
undetectable		 3jwvA-4xj6A:
20.85
3jwvB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 3jwvA-4xj6A:
undetectable
3jwvB-4xj6A:
undetectable		 3jwvA-4xj6A:
20.85
3jwvB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3jwvA-4xj6A:
undetectable
3jwvB-4xj6A:
undetectable		 3jwvA-4xj6A:
20.85
3jwvB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 3jx0A-4xj6A:
1.6
3jx0B-4xj6A:
undetectable		 3jx0A-4xj6A:
21.06
3jx0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3jx0A-4xj6A:
1.6
3jx0B-4xj6A:
undetectable		 3jx0A-4xj6A:
21.06
3jx0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 3jx0A-4xj6A:
1.6
3jx0B-4xj6A:
undetectable		 3jx0A-4xj6A:
21.06
3jx0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 3jx0A-4xj6A:
1.6
3jx0B-4xj6A:
undetectable		 3jx0A-4xj6A:
21.06
3jx0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3jx1A-4xj6A:
undetectable
3jx1B-4xj6A:
undetectable		 3jx1A-4xj6A:
21.06
3jx1B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3jx1A-4xj6A:
undetectable
3jx1B-4xj6A:
undetectable		 3jx1A-4xj6A:
21.06
3jx1B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3jx1A-4xj6A:
undetectable
3jx1B-4xj6A:
undetectable		 3jx1A-4xj6A:
21.06
3jx1B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3jx1A-4xj6A:
undetectable
3jx1B-4xj6A:
undetectable		 3jx1A-4xj6A:
21.06
3jx1B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.03A 3jx2A-4xj6A:
undetectable
3jx2B-4xj6A:
undetectable		 3jx2A-4xj6A:
21.06
3jx2B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 3jx2A-4xj6A:
undetectable
3jx2B-4xj6A:
undetectable		 3jx2A-4xj6A:
21.06
3jx2B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 3jx2A-4xj6A:
undetectable
3jx2B-4xj6A:
undetectable		 3jx2A-4xj6A:
21.06
3jx2B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 3jx2A-4xj6A:
undetectable
3jx2B-4xj6A:
undetectable		 3jx2A-4xj6A:
21.06
3jx2B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 3jx3A-4xj6A:
undetectable
3jx3B-4xj6A:
undetectable		 3jx3A-4xj6A:
21.06
3jx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.15A 3jx3A-4xj6A:
undetectable
3jx3B-4xj6A:
undetectable		 3jx3A-4xj6A:
21.06
3jx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 3jx3A-4xj6A:
undetectable
3jx3B-4xj6A:
undetectable		 3jx3A-4xj6A:
21.06
3jx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3jx3A-4xj6A:
undetectable
3jx3B-4xj6A:
undetectable		 3jx3A-4xj6A:
21.06
3jx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 3jx4A-4xj6A:
1.6
3jx4B-4xj6A:
1.6		 3jx4A-4xj6A:
21.06
3jx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.16A 3jx4A-4xj6A:
1.6
3jx4B-4xj6A:
1.6		 3jx4A-4xj6A:
21.06
3jx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 3jx5A-4xj6A:
undetectable
3jx5B-4xj6A:
1.5		 3jx5A-4xj6A:
21.06
3jx5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3jx5A-4xj6A:
undetectable
3jx5B-4xj6A:
1.5		 3jx5A-4xj6A:
21.06
3jx5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 3jx5A-4xj6A:
undetectable
3jx5B-4xj6A:
1.5		 3jx5A-4xj6A:
21.06
3jx5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 3jx5A-4xj6A:
undetectable
3jx5B-4xj6A:
1.5		 3jx5A-4xj6A:
21.06
3jx5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.03A 3jx6A-4xj6A:
undetectable
3jx6B-4xj6A:
1.7		 3jx6A-4xj6A:
21.06
3jx6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3jx6A-4xj6A:
undetectable
3jx6B-4xj6A:
1.7		 3jx6A-4xj6A:
21.06
3jx6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 3jx6A-4xj6A:
undetectable
3jx6B-4xj6A:
1.7		 3jx6A-4xj6A:
21.06
3jx6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 3jx6A-4xj6A:
undetectable
3jx6B-4xj6A:
1.7		 3jx6A-4xj6A:
21.06
3jx6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_B_CP6B563_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 12 ASP A 191
ASP A 129
HIS A 189
GLU A 127
GLU A 173
 MG  A 502 ( 3.2A)
MG  A 502 (-2.2A)
None
None
None
 1.50A 3lmyB-4xj6A:
undetectable		 3lmyB-4xj6A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3n2rA-4xj6A:
undetectable
3n2rB-4xj6A:
undetectable		 3n2rA-4xj6A:
21.06
3n2rB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3n2rA-4xj6A:
undetectable
3n2rB-4xj6A:
undetectable		 3n2rA-4xj6A:
21.06
3n2rB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3n2rA-4xj6A:
undetectable
3n2rB-4xj6A:
undetectable		 3n2rA-4xj6A:
21.06
3n2rB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3n2rA-4xj6A:
undetectable
3n2rB-4xj6A:
undetectable		 3n2rA-4xj6A:
21.06
3n2rB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 7 ARG A 276
VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.19A 3n5vA-4xj6A:
undetectable
3n5vB-4xj6A:
undetectable		 3n5vA-4xj6A:
21.06
3n5vB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.10A 3n5vA-4xj6A:
undetectable
3n5vB-4xj6A:
undetectable		 3n5vA-4xj6A:
21.06
3n5vB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 3n5vA-4xj6A:
undetectable
3n5vB-4xj6A:
undetectable		 3n5vA-4xj6A:
21.06
3n5vB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.04A 3n5yA-4xj6A:
undetectable
3n5yB-4xj6A:
undetectable		 3n5yA-4xj6A:
21.06
3n5yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3n5yA-4xj6A:
undetectable
3n5yB-4xj6A:
undetectable		 3n5yA-4xj6A:
21.06
3n5yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.11A 3n5yA-4xj6A:
undetectable
3n5yB-4xj6A:
undetectable		 3n5yA-4xj6A:
21.06
3n5yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3n5yA-4xj6A:
undetectable
3n5yB-4xj6A:
undetectable		 3n5yA-4xj6A:
21.06
3n5yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.04A 3n5zA-4xj6A:
undetectable
3n5zB-4xj6A:
undetectable		 3n5zA-4xj6A:
21.06
3n5zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3n5zA-4xj6A:
undetectable
3n5zB-4xj6A:
undetectable		 3n5zA-4xj6A:
21.06
3n5zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 3n5zA-4xj6A:
undetectable
3n5zB-4xj6A:
undetectable		 3n5zA-4xj6A:
21.06
3n5zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 3n5zA-4xj6A:
undetectable
3n5zB-4xj6A:
undetectable		 3n5zA-4xj6A:
21.06
3n5zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.13A 3n61A-4xj6A:
undetectable
3n61B-4xj6A:
undetectable		 3n61A-4xj6A:
21.06
3n61B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 3n61A-4xj6A:
undetectable
3n61B-4xj6A:
undetectable		 3n61A-4xj6A:
21.06
3n61B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.18A 3n65A-4xj6A:
undetectable
3n65B-4xj6A:
undetectable		 3n65A-4xj6A:
20.85
3n65B-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.07A 3nljA-4xj6A:
undetectable
3nljB-4xj6A:
undetectable		 3nljA-4xj6A:
21.06
3nljB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3nljA-4xj6A:
undetectable
3nljB-4xj6A:
undetectable		 3nljA-4xj6A:
21.06
3nljB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 3nljA-4xj6A:
undetectable
3nljB-4xj6A:
undetectable		 3nljA-4xj6A:
21.06
3nljB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3nljA-4xj6A:
undetectable
3nljB-4xj6A:
undetectable		 3nljA-4xj6A:
21.06
3nljB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3nlkA-4xj6A:
undetectable
3nlkB-4xj6A:
undetectable		 3nlkA-4xj6A:
20.85
3nlkB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.05A 3nlkA-4xj6A:
undetectable
3nlkB-4xj6A:
undetectable		 3nlkA-4xj6A:
20.85
3nlkB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 3nlkA-4xj6A:
undetectable
3nlkB-4xj6A:
undetectable		 3nlkA-4xj6A:
20.85
3nlkB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 3nlkA-4xj6A:
undetectable
3nlkB-4xj6A:
undetectable		 3nlkA-4xj6A:
20.85
3nlkB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3nlmA-4xj6A:
undetectable
3nlmB-4xj6A:
undetectable		 3nlmA-4xj6A:
21.06
3nlmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3nlmA-4xj6A:
undetectable
3nlmB-4xj6A:
undetectable		 3nlmA-4xj6A:
21.06
3nlmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 3nlmA-4xj6A:
undetectable
3nlmB-4xj6A:
undetectable		 3nlmA-4xj6A:
21.06
3nlmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 3nlmA-4xj6A:
undetectable
3nlmB-4xj6A:
undetectable		 3nlmA-4xj6A:
21.06
3nlmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 3nlnA-4xj6A:
undetectable
3nlnB-4xj6A:
1.6		 3nlnA-4xj6A:
20.85
3nlnB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3nlnA-4xj6A:
undetectable
3nlnB-4xj6A:
1.6		 3nlnA-4xj6A:
20.85
3nlnB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3nlnA-4xj6A:
undetectable
3nlnB-4xj6A:
1.6		 3nlnA-4xj6A:
20.85
3nlnB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3nlnA-4xj6A:
undetectable
3nlnB-4xj6A:
1.6		 3nlnA-4xj6A:
20.85
3nlnB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.18A 3nloA-4xj6A:
undetectable
3nloB-4xj6A:
undetectable		 3nloA-4xj6A:
20.85
3nloB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3nloA-4xj6A:
undetectable
3nloB-4xj6A:
undetectable		 3nloA-4xj6A:
20.85
3nloB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 3nloA-4xj6A:
undetectable
3nloB-4xj6A:
undetectable		 3nloA-4xj6A:
20.85
3nloB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 3nloA-4xj6A:
undetectable
3nloB-4xj6A:
undetectable		 3nloA-4xj6A:
20.85
3nloB-4xj6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 3nlpA-4xj6A:
undetectable
3nlpB-4xj6A:
undetectable		 3nlpA-4xj6A:
21.06
3nlpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.14A 3nlpA-4xj6A:
undetectable
3nlpB-4xj6A:
undetectable		 3nlpA-4xj6A:
21.06
3nlpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3nlpA-4xj6A:
undetectable
3nlpB-4xj6A:
undetectable		 3nlpA-4xj6A:
21.06
3nlpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 3nlpA-4xj6A:
undetectable
3nlpB-4xj6A:
undetectable		 3nlpA-4xj6A:
21.06
3nlpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3nlqA-4xj6A:
undetectable
3nlqB-4xj6A:
undetectable		 3nlqA-4xj6A:
21.06
3nlqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3nlqA-4xj6A:
undetectable
3nlqB-4xj6A:
undetectable		 3nlqA-4xj6A:
21.06
3nlqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 3nlqA-4xj6A:
undetectable
3nlqB-4xj6A:
undetectable		 3nlqA-4xj6A:
21.06
3nlqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.14A 3nlqA-4xj6A:
undetectable
3nlqB-4xj6A:
undetectable		 3nlqA-4xj6A:
21.06
3nlqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 3nlrA-4xj6A:
undetectable
3nlrB-4xj6A:
undetectable		 3nlrA-4xj6A:
21.06
3nlrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3nlrA-4xj6A:
undetectable
3nlrB-4xj6A:
undetectable		 3nlrA-4xj6A:
21.06
3nlrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 3nlrA-4xj6A:
undetectable
3nlrB-4xj6A:
undetectable		 3nlrA-4xj6A:
21.06
3nlrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3nlvA-4xj6A:
undetectable
3nlvB-4xj6A:
undetectable		 3nlvA-4xj6A:
21.06
3nlvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 3nlvA-4xj6A:
undetectable
3nlvB-4xj6A:
undetectable		 3nlvA-4xj6A:
21.06
3nlvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 3nlvA-4xj6A:
undetectable
3nlvB-4xj6A:
undetectable		 3nlvA-4xj6A:
21.06
3nlvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3nlvA-4xj6A:
undetectable
3nlvB-4xj6A:
undetectable		 3nlvA-4xj6A:
21.06
3nlvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3nlwA-4xj6A:
undetectable
3nlwB-4xj6A:
undetectable		 3nlwA-4xj6A:
21.06
3nlwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3nlwA-4xj6A:
undetectable
3nlwB-4xj6A:
undetectable		 3nlwA-4xj6A:
21.06
3nlwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 3nlwA-4xj6A:
undetectable
3nlwB-4xj6A:
undetectable		 3nlwA-4xj6A:
21.06
3nlwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3nlwA-4xj6A:
undetectable
3nlwB-4xj6A:
undetectable		 3nlwA-4xj6A:
21.06
3nlwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3nlxA-4xj6A:
undetectable
3nlxB-4xj6A:
undetectable		 3nlxA-4xj6A:
21.06
3nlxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3nlxA-4xj6A:
undetectable
3nlxB-4xj6A:
undetectable		 3nlxA-4xj6A:
21.06
3nlxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 3nlxA-4xj6A:
undetectable
3nlxB-4xj6A:
undetectable		 3nlxA-4xj6A:
21.06
3nlxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3nlxA-4xj6A:
undetectable
3nlxB-4xj6A:
undetectable		 3nlxA-4xj6A:
21.06
3nlxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 3nlyA-4xj6A:
undetectable
3nlyB-4xj6A:
undetectable		 3nlyA-4xj6A:
21.06
3nlyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3nlyA-4xj6A:
undetectable
3nlyB-4xj6A:
undetectable		 3nlyA-4xj6A:
21.06
3nlyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 3nlyA-4xj6A:
undetectable
3nlyB-4xj6A:
undetectable		 3nlyA-4xj6A:
21.06
3nlyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3nlyA-4xj6A:
undetectable
3nlyB-4xj6A:
undetectable		 3nlyA-4xj6A:
21.06
3nlyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 3nlzA-4xj6A:
undetectable
3nlzB-4xj6A:
undetectable		 3nlzA-4xj6A:
21.06
3nlzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3nlzA-4xj6A:
undetectable
3nlzB-4xj6A:
undetectable		 3nlzA-4xj6A:
21.06
3nlzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3nlzA-4xj6A:
undetectable
3nlzB-4xj6A:
undetectable		 3nlzA-4xj6A:
21.06
3nlzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3nlzA-4xj6A:
undetectable
3nlzB-4xj6A:
undetectable		 3nlzA-4xj6A:
21.06
3nlzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 3nm0A-4xj6A:
2.2
3nm0B-4xj6A:
undetectable		 3nm0A-4xj6A:
21.06
3nm0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3nm0A-4xj6A:
2.2
3nm0B-4xj6A:
undetectable		 3nm0A-4xj6A:
21.06
3nm0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 3nm0A-4xj6A:
2.2
3nm0B-4xj6A:
undetectable		 3nm0A-4xj6A:
21.06
3nm0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3nm0A-4xj6A:
2.2
3nm0B-4xj6A:
undetectable		 3nm0A-4xj6A:
21.06
3nm0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 3nnyA-4xj6A:
undetectable
3nnyB-4xj6A:
undetectable		 3nnyA-4xj6A:
21.06
3nnyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3nnyA-4xj6A:
undetectable
3nnyB-4xj6A:
undetectable		 3nnyA-4xj6A:
21.06
3nnyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3nnyA-4xj6A:
undetectable
3nnyB-4xj6A:
undetectable		 3nnyA-4xj6A:
21.06
3nnyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3nnyA-4xj6A:
undetectable
3nnyB-4xj6A:
undetectable		 3nnyA-4xj6A:
21.06
3nnyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3nnzA-4xj6A:
undetectable
3nnzB-4xj6A:
undetectable		 3nnzA-4xj6A:
21.06
3nnzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 3nnzA-4xj6A:
undetectable
3nnzB-4xj6A:
undetectable		 3nnzA-4xj6A:
21.06
3nnzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3nnzA-4xj6A:
undetectable
3nnzB-4xj6A:
undetectable		 3nnzA-4xj6A:
21.06
3nnzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3nnzA-4xj6A:
undetectable
3nnzB-4xj6A:
undetectable		 3nnzA-4xj6A:
21.06
3nnzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 3pneA-4xj6A:
2.1
3pneB-4xj6A:
undetectable		 3pneA-4xj6A:
21.06
3pneB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3pneA-4xj6A:
2.1
3pneB-4xj6A:
undetectable		 3pneA-4xj6A:
21.06
3pneB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3pneA-4xj6A:
2.1
3pneB-4xj6A:
undetectable		 3pneA-4xj6A:
21.06
3pneB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3pneA-4xj6A:
2.1
3pneB-4xj6A:
undetectable		 3pneA-4xj6A:
21.06
3pneB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 3pnfA-4xj6A:
undetectable
3pnfB-4xj6A:
undetectable		 3pnfA-4xj6A:
21.06
3pnfB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3pnfA-4xj6A:
undetectable
3pnfB-4xj6A:
undetectable		 3pnfA-4xj6A:
21.06
3pnfB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3pnfA-4xj6A:
undetectable
3pnfB-4xj6A:
undetectable		 3pnfA-4xj6A:
21.06
3pnfB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3pnfA-4xj6A:
undetectable
3pnfB-4xj6A:
undetectable		 3pnfA-4xj6A:
21.06
3pnfB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 3pngA-4xj6A:
undetectable
3pngB-4xj6A:
undetectable		 3pngA-4xj6A:
21.06
3pngB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3pngA-4xj6A:
undetectable
3pngB-4xj6A:
undetectable		 3pngA-4xj6A:
21.06
3pngB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 3pngA-4xj6A:
undetectable
3pngB-4xj6A:
undetectable		 3pngA-4xj6A:
21.06
3pngB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3pngA-4xj6A:
undetectable
3pngB-4xj6A:
undetectable		 3pngA-4xj6A:
21.06
3pngB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_1
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 GLY A 320
THR A 321
LEU A 318
ASP A   4
 None
 0.85A 3ps9A-4xj6A:
undetectable		 3ps9A-4xj6A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 3q99A-4xj6A:
undetectable
3q99B-4xj6A:
undetectable		 3q99A-4xj6A:
21.06
3q99B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3q99A-4xj6A:
undetectable
3q99B-4xj6A:
undetectable		 3q99A-4xj6A:
21.06
3q99B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3q99A-4xj6A:
undetectable
3q99B-4xj6A:
undetectable		 3q99A-4xj6A:
21.06
3q99B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 3q99A-4xj6A:
undetectable
3q99B-4xj6A:
undetectable		 3q99A-4xj6A:
21.06
3q99B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 3q9aA-4xj6A:
undetectable
3q9aB-4xj6A:
undetectable		 3q9aA-4xj6A:
21.06
3q9aB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 3q9aA-4xj6A:
undetectable
3q9aB-4xj6A:
undetectable		 3q9aA-4xj6A:
21.06
3q9aB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3q9aA-4xj6A:
undetectable
3q9aB-4xj6A:
undetectable		 3q9aA-4xj6A:
21.06
3q9aB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.06A 3q9aA-4xj6A:
undetectable
3q9aB-4xj6A:
undetectable		 3q9aA-4xj6A:
21.06
3q9aB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 3rqjA-4xj6A:
undetectable
3rqjB-4xj6A:
undetectable		 3rqjA-4xj6A:
21.06
3rqjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.13A 3rqjA-4xj6A:
undetectable
3rqjB-4xj6A:
undetectable		 3rqjA-4xj6A:
21.06
3rqjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3rqjA-4xj6A:
undetectable
3rqjB-4xj6A:
undetectable		 3rqjA-4xj6A:
21.06
3rqjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3rqjA-4xj6A:
undetectable
3rqjB-4xj6A:
undetectable		 3rqjA-4xj6A:
21.06
3rqjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 3rqkA-4xj6A:
undetectable
3rqkB-4xj6A:
undetectable		 3rqkA-4xj6A:
21.06
3rqkB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3rqkA-4xj6A:
undetectable
3rqkB-4xj6A:
undetectable		 3rqkA-4xj6A:
21.06
3rqkB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3rqkA-4xj6A:
undetectable
3rqkB-4xj6A:
undetectable		 3rqkA-4xj6A:
21.06
3rqkB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3rqkA-4xj6A:
undetectable
3rqkB-4xj6A:
undetectable		 3rqkA-4xj6A:
21.06
3rqkB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 3rqlA-4xj6A:
2.2
3rqlB-4xj6A:
undetectable		 3rqlA-4xj6A:
21.06
3rqlB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3rqlA-4xj6A:
2.2
3rqlB-4xj6A:
undetectable		 3rqlA-4xj6A:
21.06
3rqlB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3rqlA-4xj6A:
2.2
3rqlB-4xj6A:
undetectable		 3rqlA-4xj6A:
21.06
3rqlB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3rqlA-4xj6A:
2.2
3rqlB-4xj6A:
undetectable		 3rqlA-4xj6A:
21.06
3rqlB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 3rqmA-4xj6A:
undetectable
3rqmB-4xj6A:
undetectable		 3rqmA-4xj6A:
21.06
3rqmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3rqmA-4xj6A:
undetectable
3rqmB-4xj6A:
undetectable		 3rqmA-4xj6A:
21.06
3rqmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 3rqmA-4xj6A:
undetectable
3rqmB-4xj6A:
undetectable		 3rqmA-4xj6A:
21.06
3rqmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3rqmA-4xj6A:
undetectable
3rqmB-4xj6A:
undetectable		 3rqmA-4xj6A:
21.06
3rqmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3rqnA-4xj6A:
2.2
3rqnB-4xj6A:
undetectable		 3rqnA-4xj6A:
21.06
3rqnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3rqnA-4xj6A:
2.2
3rqnB-4xj6A:
undetectable		 3rqnA-4xj6A:
21.06
3rqnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3rqnA-4xj6A:
2.2
3rqnB-4xj6A:
undetectable		 3rqnA-4xj6A:
21.06
3rqnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3rqnA-4xj6A:
2.2
3rqnB-4xj6A:
undetectable		 3rqnA-4xj6A:
21.06
3rqnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 3svpA-4xj6A:
undetectable
3svpB-4xj6A:
undetectable		 3svpA-4xj6A:
21.06
3svpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3svpA-4xj6A:
undetectable
3svpB-4xj6A:
undetectable		 3svpA-4xj6A:
21.06
3svpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.22A 3svpA-4xj6A:
undetectable
3svpB-4xj6A:
undetectable		 3svpA-4xj6A:
21.06
3svpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3svpA-4xj6A:
undetectable
3svpB-4xj6A:
undetectable		 3svpA-4xj6A:
21.06
3svpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3svqA-4xj6A:
undetectable
3svqB-4xj6A:
undetectable		 3svqA-4xj6A:
21.06
3svqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3svqA-4xj6A:
undetectable
3svqB-4xj6A:
undetectable		 3svqA-4xj6A:
21.06
3svqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 3svqA-4xj6A:
undetectable
3svqB-4xj6A:
undetectable		 3svqA-4xj6A:
21.06
3svqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3svqA-4xj6A:
undetectable
3svqB-4xj6A:
undetectable		 3svqA-4xj6A:
21.06
3svqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 100
PHE A  45
THR A 158
LEU A  85
 None
 1.08A 3t3sC-4xj6A:
undetectable		 3t3sC-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3tylA-4xj6A:
undetectable
3tylB-4xj6A:
undetectable		 3tylA-4xj6A:
21.06
3tylB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3tylA-4xj6A:
undetectable
3tylB-4xj6A:
undetectable		 3tylA-4xj6A:
21.06
3tylB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 3tylA-4xj6A:
undetectable
3tylB-4xj6A:
undetectable		 3tylA-4xj6A:
21.06
3tylB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3tylA-4xj6A:
undetectable
3tylB-4xj6A:
undetectable		 3tylA-4xj6A:
21.06
3tylB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 3tymA-4xj6A:
1.6
3tymB-4xj6A:
undetectable		 3tymA-4xj6A:
21.06
3tymB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3tymA-4xj6A:
1.6
3tymB-4xj6A:
undetectable		 3tymA-4xj6A:
21.06
3tymB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 3tymA-4xj6A:
1.7
3tymB-4xj6A:
undetectable		 3tymA-4xj6A:
21.06
3tymB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3tymA-4xj6A:
1.7
3tymB-4xj6A:
undetectable		 3tymA-4xj6A:
21.06
3tymB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 3tynA-4xj6A:
undetectable
3tynB-4xj6A:
undetectable		 3tynA-4xj6A:
21.06
3tynB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3tynA-4xj6A:
undetectable
3tynB-4xj6A:
undetectable		 3tynA-4xj6A:
21.06
3tynB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3tynA-4xj6A:
undetectable
3tynB-4xj6A:
undetectable		 3tynA-4xj6A:
21.06
3tynB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3tynA-4xj6A:
undetectable
3tynB-4xj6A:
undetectable		 3tynA-4xj6A:
21.06
3tynB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3tyoA-4xj6A:
1.6
3tyoB-4xj6A:
1.7		 3tyoA-4xj6A:
21.06
3tyoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3tyoA-4xj6A:
1.6
3tyoB-4xj6A:
1.7		 3tyoA-4xj6A:
21.06
3tyoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 3tyoA-4xj6A:
1.6
3tyoB-4xj6A:
1.7		 3tyoA-4xj6A:
21.06
3tyoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 3tyoA-4xj6A:
1.6
3tyoB-4xj6A:
1.7		 3tyoA-4xj6A:
21.06
3tyoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.07A 3ufoA-4xj6A:
1.6
3ufoB-4xj6A:
undetectable		 3ufoA-4xj6A:
21.06
3ufoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3ufoA-4xj6A:
1.6
3ufoB-4xj6A:
undetectable		 3ufoA-4xj6A:
21.06
3ufoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 3ufoA-4xj6A:
1.6
3ufoB-4xj6A:
undetectable		 3ufoA-4xj6A:
21.06
3ufoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.14A 3ufoA-4xj6A:
1.6
3ufoB-4xj6A:
undetectable		 3ufoA-4xj6A:
21.06
3ufoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.16A 3ufpA-4xj6A:
undetectable
3ufpB-4xj6A:
undetectable		 3ufpA-4xj6A:
21.06
3ufpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3ufpA-4xj6A:
undetectable
3ufpB-4xj6A:
undetectable		 3ufpA-4xj6A:
21.06
3ufpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.27A 3ufpA-4xj6A:
undetectable
3ufpB-4xj6A:
undetectable		 3ufpA-4xj6A:
21.06
3ufpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 3ufpA-4xj6A:
undetectable
3ufpB-4xj6A:
undetectable		 3ufpA-4xj6A:
21.06
3ufpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 3ufqA-4xj6A:
undetectable
3ufqB-4xj6A:
undetectable		 3ufqA-4xj6A:
21.06
3ufqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3ufqA-4xj6A:
undetectable
3ufqB-4xj6A:
undetectable		 3ufqA-4xj6A:
21.06
3ufqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 3ufqA-4xj6A:
undetectable
3ufqB-4xj6A:
undetectable		 3ufqA-4xj6A:
21.06
3ufqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3ufqA-4xj6A:
undetectable
3ufqB-4xj6A:
undetectable		 3ufqA-4xj6A:
21.06
3ufqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.39A 3ufrA-4xj6A:
undetectable
3ufrB-4xj6A:
1.7		 3ufrA-4xj6A:
21.06
3ufrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 3ufrA-4xj6A:
undetectable
3ufrB-4xj6A:
1.7		 3ufrA-4xj6A:
21.06
3ufrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 3ufrA-4xj6A:
undetectable
3ufrB-4xj6A:
1.7		 3ufrA-4xj6A:
21.06
3ufrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3ufrA-4xj6A:
undetectable
3ufrB-4xj6A:
1.7		 3ufrA-4xj6A:
21.06
3ufrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 3ufsA-4xj6A:
undetectable
3ufsB-4xj6A:
undetectable		 3ufsA-4xj6A:
21.06
3ufsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 3ufsA-4xj6A:
undetectable
3ufsB-4xj6A:
undetectable		 3ufsA-4xj6A:
21.06
3ufsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 3ufsA-4xj6A:
undetectable
3ufsB-4xj6A:
undetectable		 3ufsA-4xj6A:
21.06
3ufsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3ufsA-4xj6A:
undetectable
3ufsB-4xj6A:
undetectable		 3ufsA-4xj6A:
21.06
3ufsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.18A 3uftA-4xj6A:
undetectable
3uftB-4xj6A:
undetectable		 3uftA-4xj6A:
21.06
3uftB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.14A 3uftA-4xj6A:
undetectable
3uftB-4xj6A:
undetectable		 3uftA-4xj6A:
21.06
3uftB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 3uftA-4xj6A:
undetectable
3uftB-4xj6A:
undetectable		 3uftA-4xj6A:
21.06
3uftB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3uftA-4xj6A:
undetectable
3uftB-4xj6A:
undetectable		 3uftA-4xj6A:
21.06
3uftB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3ufuA-4xj6A:
undetectable
3ufuB-4xj6A:
undetectable		 3ufuA-4xj6A:
21.06
3ufuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3ufuA-4xj6A:
undetectable
3ufuB-4xj6A:
undetectable		 3ufuA-4xj6A:
21.06
3ufuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 3ufuA-4xj6A:
undetectable
3ufuB-4xj6A:
undetectable		 3ufuA-4xj6A:
21.06
3ufuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 3ufuA-4xj6A:
undetectable
3ufuB-4xj6A:
undetectable		 3ufuA-4xj6A:
21.06
3ufuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 3ufvA-4xj6A:
undetectable
3ufvB-4xj6A:
undetectable		 3ufvA-4xj6A:
21.06
3ufvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 3ufvA-4xj6A:
undetectable
3ufvB-4xj6A:
undetectable		 3ufvA-4xj6A:
21.06
3ufvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 3ufvA-4xj6A:
undetectable
3ufvB-4xj6A:
undetectable		 3ufvA-4xj6A:
21.06
3ufvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 3ufvA-4xj6A:
undetectable
3ufvB-4xj6A:
undetectable		 3ufvA-4xj6A:
21.06
3ufvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 3ufwA-4xj6A:
undetectable
3ufwB-4xj6A:
undetectable		 3ufwA-4xj6A:
21.06
3ufwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 3ufwA-4xj6A:
undetectable
3ufwB-4xj6A:
undetectable		 3ufwA-4xj6A:
21.06
3ufwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 3ufwA-4xj6A:
undetectable
3ufwB-4xj6A:
undetectable		 3ufwA-4xj6A:
21.06
3ufwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 3ufwA-4xj6A:
undetectable
3ufwB-4xj6A:
undetectable		 3ufwA-4xj6A:
21.06
3ufwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4c39A-4xj6A:
undetectable
4c39B-4xj6A:
undetectable		 4c39A-4xj6A:
21.06
4c39B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4c39A-4xj6A:
undetectable
4c39B-4xj6A:
undetectable		 4c39A-4xj6A:
21.06
4c39B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 4c39A-4xj6A:
undetectable
4c39B-4xj6A:
undetectable		 4c39A-4xj6A:
21.06
4c39B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4c39A-4xj6A:
undetectable
4c39B-4xj6A:
undetectable		 4c39A-4xj6A:
21.06
4c39B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4camA-4xj6A:
1.7
4camB-4xj6A:
undetectable		 4camA-4xj6A:
21.06
4camB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4camA-4xj6A:
1.7
4camB-4xj6A:
undetectable		 4camA-4xj6A:
21.06
4camB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4camA-4xj6A:
1.7
4camB-4xj6A:
undetectable		 4camA-4xj6A:
21.06
4camB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4camA-4xj6A:
1.7
4camB-4xj6A:
undetectable		 4camA-4xj6A:
21.06
4camB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4canA-4xj6A:
undetectable
4canB-4xj6A:
undetectable		 4canA-4xj6A:
21.06
4canB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 4canA-4xj6A:
undetectable
4canB-4xj6A:
undetectable		 4canA-4xj6A:
21.06
4canB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 4canA-4xj6A:
undetectable
4canB-4xj6A:
undetectable		 4canA-4xj6A:
21.06
4canB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4canA-4xj6A:
undetectable
4canB-4xj6A:
undetectable		 4canA-4xj6A:
21.06
4canB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 4caoA-4xj6A:
undetectable
4caoB-4xj6A:
undetectable		 4caoA-4xj6A:
21.06
4caoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4caoA-4xj6A:
undetectable
4caoB-4xj6A:
undetectable		 4caoA-4xj6A:
21.06
4caoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4caoA-4xj6A:
undetectable
4caoB-4xj6A:
undetectable		 4caoA-4xj6A:
21.06
4caoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4caoA-4xj6A:
undetectable
4caoB-4xj6A:
undetectable		 4caoA-4xj6A:
21.06
4caoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 4capA-4xj6A:
1.6
4capB-4xj6A:
undetectable		 4capA-4xj6A:
21.06
4capB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.04A 4capA-4xj6A:
1.6
4capB-4xj6A:
undetectable		 4capA-4xj6A:
21.06
4capB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4capA-4xj6A:
1.6
4capB-4xj6A:
undetectable		 4capA-4xj6A:
21.06
4capB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 4capA-4xj6A:
1.6
4capB-4xj6A:
undetectable		 4capA-4xj6A:
21.06
4capB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 4caqA-4xj6A:
undetectable
4caqB-4xj6A:
undetectable		 4caqA-4xj6A:
21.06
4caqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 4caqA-4xj6A:
undetectable
4caqB-4xj6A:
undetectable		 4caqA-4xj6A:
21.06
4caqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4caqA-4xj6A:
undetectable
4caqB-4xj6A:
undetectable		 4caqA-4xj6A:
21.06
4caqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4caqA-4xj6A:
undetectable
4caqB-4xj6A:
undetectable		 4caqA-4xj6A:
21.06
4caqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.22A 4cdtA-4xj6A:
undetectable
4cdtB-4xj6A:
undetectable		 4cdtA-4xj6A:
21.06
4cdtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 4cdtA-4xj6A:
undetectable
4cdtB-4xj6A:
undetectable		 4cdtA-4xj6A:
21.06
4cdtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4cdtA-4xj6A:
undetectable
4cdtB-4xj6A:
undetectable		 4cdtA-4xj6A:
21.06
4cdtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4cdtA-4xj6A:
undetectable
4cdtB-4xj6A:
undetectable		 4cdtA-4xj6A:
21.06
4cdtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4ctpA-4xj6A:
undetectable
4ctpB-4xj6A:
undetectable		 4ctpA-4xj6A:
21.06
4ctpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 4ctpA-4xj6A:
undetectable
4ctpB-4xj6A:
undetectable		 4ctpA-4xj6A:
21.06
4ctpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 4ctpA-4xj6A:
undetectable
4ctpB-4xj6A:
undetectable		 4ctpA-4xj6A:
21.06
4ctpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4ctpA-4xj6A:
undetectable
4ctpB-4xj6A:
undetectable		 4ctpA-4xj6A:
21.06
4ctpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4ctqA-4xj6A:
undetectable
4ctqB-4xj6A:
undetectable		 4ctqA-4xj6A:
21.06
4ctqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4ctqA-4xj6A:
undetectable
4ctqB-4xj6A:
undetectable		 4ctqA-4xj6A:
21.06
4ctqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4ctqA-4xj6A:
undetectable
4ctqB-4xj6A:
undetectable		 4ctqA-4xj6A:
21.06
4ctqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4ctqA-4xj6A:
undetectable
4ctqB-4xj6A:
undetectable		 4ctqA-4xj6A:
21.06
4ctqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.06A 4ctrA-4xj6A:
undetectable
4ctrB-4xj6A:
undetectable		 4ctrA-4xj6A:
21.06
4ctrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4ctrA-4xj6A:
undetectable
4ctrB-4xj6A:
undetectable		 4ctrA-4xj6A:
21.06
4ctrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4ctrA-4xj6A:
undetectable
4ctrB-4xj6A:
undetectable		 4ctrA-4xj6A:
21.06
4ctrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 4ctrA-4xj6A:
undetectable
4ctrB-4xj6A:
undetectable		 4ctrA-4xj6A:
21.06
4ctrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 4cttA-4xj6A:
undetectable
4cttB-4xj6A:
undetectable		 4cttA-4xj6A:
21.06
4cttB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 4cttA-4xj6A:
undetectable
4cttB-4xj6A:
undetectable		 4cttA-4xj6A:
21.06
4cttB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 4cttA-4xj6A:
undetectable
4cttB-4xj6A:
undetectable		 4cttA-4xj6A:
21.06
4cttB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 4cttA-4xj6A:
undetectable
4cttB-4xj6A:
undetectable		 4cttA-4xj6A:
21.06
4cttB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 4ctuA-4xj6A:
undetectable
4ctuB-4xj6A:
undetectable		 4ctuA-4xj6A:
21.06
4ctuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4ctuA-4xj6A:
undetectable
4ctuB-4xj6A:
undetectable		 4ctuA-4xj6A:
21.06
4ctuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 4ctuA-4xj6A:
undetectable
4ctuB-4xj6A:
undetectable		 4ctuA-4xj6A:
21.06
4ctuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4ctuA-4xj6A:
undetectable
4ctuB-4xj6A:
undetectable		 4ctuA-4xj6A:
21.06
4ctuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4ctvA-4xj6A:
undetectable
4ctvB-4xj6A:
undetectable		 4ctvA-4xj6A:
21.06
4ctvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 4ctvA-4xj6A:
undetectable
4ctvB-4xj6A:
undetectable		 4ctvA-4xj6A:
21.06
4ctvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4ctvA-4xj6A:
undetectable
4ctvB-4xj6A:
undetectable		 4ctvA-4xj6A:
21.06
4ctvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 4ctvA-4xj6A:
undetectable
4ctvB-4xj6A:
undetectable		 4ctvA-4xj6A:
21.06
4ctvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4ctwA-4xj6A:
undetectable
4ctwB-4xj6A:
undetectable		 4ctwA-4xj6A:
21.06
4ctwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 4ctwA-4xj6A:
undetectable
4ctwB-4xj6A:
undetectable		 4ctwA-4xj6A:
21.06
4ctwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 4ctwA-4xj6A:
undetectable
4ctwB-4xj6A:
undetectable		 4ctwA-4xj6A:
21.06
4ctwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4ctwA-4xj6A:
undetectable
4ctwB-4xj6A:
undetectable		 4ctwA-4xj6A:
21.06
4ctwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 4ctxA-4xj6A:
undetectable
4ctxB-4xj6A:
undetectable		 4ctxA-4xj6A:
21.06
4ctxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4ctxA-4xj6A:
undetectable
4ctxB-4xj6A:
undetectable		 4ctxA-4xj6A:
21.06
4ctxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4ctxA-4xj6A:
undetectable
4ctxB-4xj6A:
undetectable		 4ctxA-4xj6A:
21.06
4ctxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4ctxA-4xj6A:
undetectable
4ctxB-4xj6A:
undetectable		 4ctxA-4xj6A:
21.06
4ctxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 4cx3A-4xj6A:
undetectable
4cx3B-4xj6A:
undetectable		 4cx3A-4xj6A:
21.06
4cx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4cx3A-4xj6A:
undetectable
4cx3B-4xj6A:
undetectable		 4cx3A-4xj6A:
21.06
4cx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 4cx3A-4xj6A:
undetectable
4cx3B-4xj6A:
undetectable		 4cx3A-4xj6A:
21.06
4cx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4cx3A-4xj6A:
undetectable
4cx3B-4xj6A:
undetectable		 4cx3A-4xj6A:
21.06
4cx3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 4cx4A-4xj6A:
undetectable
4cx4B-4xj6A:
undetectable		 4cx4A-4xj6A:
21.06
4cx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 4cx4A-4xj6A:
undetectable
4cx4B-4xj6A:
undetectable		 4cx4A-4xj6A:
21.06
4cx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4cx4A-4xj6A:
undetectable
4cx4B-4xj6A:
undetectable		 4cx4A-4xj6A:
21.06
4cx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4cx4A-4xj6A:
undetectable
4cx4B-4xj6A:
undetectable		 4cx4A-4xj6A:
21.06
4cx4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4cx5A-4xj6A:
undetectable
4cx5B-4xj6A:
undetectable		 4cx5A-4xj6A:
21.28
4cx5B-4xj6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4cx5A-4xj6A:
undetectable
4cx5B-4xj6A:
undetectable		 4cx5A-4xj6A:
21.28
4cx5B-4xj6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4cx5A-4xj6A:
undetectable
4cx5B-4xj6A:
undetectable		 4cx5A-4xj6A:
21.28
4cx5B-4xj6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4cx5A-4xj6A:
undetectable
4cx5B-4xj6A:
undetectable		 4cx5A-4xj6A:
21.28
4cx5B-4xj6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4cx6A-4xj6A:
0.1
4cx6B-4xj6A:
undetectable		 4cx6A-4xj6A:
21.28
4cx6B-4xj6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 4cx6A-4xj6A:
0.1
4cx6B-4xj6A:
undetectable		 4cx6A-4xj6A:
21.28
4cx6B-4xj6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4cx6A-4xj6A:
0.1
4cx6B-4xj6A:
undetectable		 4cx6A-4xj6A:
21.28
4cx6B-4xj6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4cx6A-4xj6A:
0.1
4cx6B-4xj6A:
undetectable		 4cx6A-4xj6A:
21.28
4cx6B-4xj6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 ARG A 276
ILE A 271
PHE A 264
GLU A 266
 None
 1.27A 4cx7C-4xj6A:
0.0
4cx7D-4xj6A:
undetectable		 4cx7C-4xj6A:
22.82
4cx7D-4xj6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 4d1nA-4xj6A:
undetectable
4d1nB-4xj6A:
undetectable		 4d1nA-4xj6A:
19.92
4d1nB-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.05A 4d1nA-4xj6A:
undetectable
4d1nB-4xj6A:
undetectable		 4d1nA-4xj6A:
19.92
4d1nB-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.10A 4d1nA-4xj6A:
undetectable
4d1nB-4xj6A:
undetectable		 4d1nA-4xj6A:
19.92
4d1nB-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4d1nA-4xj6A:
undetectable
4d1nB-4xj6A:
undetectable		 4d1nA-4xj6A:
19.92
4d1nB-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4d1nC-4xj6A:
undetectable
4d1nD-4xj6A:
undetectable		 4d1nC-4xj6A:
19.92
4d1nD-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 4d1nC-4xj6A:
undetectable
4d1nD-4xj6A:
undetectable		 4d1nC-4xj6A:
19.92
4d1nD-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.10A 4d1nC-4xj6A:
undetectable
4d1nD-4xj6A:
undetectable		 4d1nC-4xj6A:
19.92
4d1nD-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.05A 4d1nC-4xj6A:
undetectable
4d1nD-4xj6A:
undetectable		 4d1nC-4xj6A:
19.92
4d1nD-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4d2yA-4xj6A:
undetectable
4d2yB-4xj6A:
undetectable		 4d2yA-4xj6A:
21.06
4d2yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 4d2yA-4xj6A:
undetectable
4d2yB-4xj6A:
undetectable		 4d2yA-4xj6A:
21.06
4d2yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 4d2yA-4xj6A:
undetectable
4d2yB-4xj6A:
undetectable		 4d2yA-4xj6A:
21.06
4d2yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.06A 4d2yA-4xj6A:
undetectable
4d2yB-4xj6A:
undetectable		 4d2yA-4xj6A:
21.06
4d2yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 4d2zA-4xj6A:
1.7
4d2zB-4xj6A:
undetectable		 4d2zA-4xj6A:
21.06
4d2zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 4d2zA-4xj6A:
1.7
4d2zB-4xj6A:
undetectable		 4d2zA-4xj6A:
21.06
4d2zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4d2zA-4xj6A:
1.7
4d2zB-4xj6A:
undetectable		 4d2zA-4xj6A:
21.06
4d2zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4d2zA-4xj6A:
1.7
4d2zB-4xj6A:
undetectable		 4d2zA-4xj6A:
21.06
4d2zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4d30A-4xj6A:
undetectable
4d30B-4xj6A:
undetectable		 4d30A-4xj6A:
21.06
4d30B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4d30A-4xj6A:
undetectable
4d30B-4xj6A:
undetectable		 4d30A-4xj6A:
21.06
4d30B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 4d30A-4xj6A:
undetectable
4d30B-4xj6A:
undetectable		 4d30A-4xj6A:
21.06
4d30B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 4d30A-4xj6A:
undetectable
4d30B-4xj6A:
undetectable		 4d30A-4xj6A:
21.06
4d30B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4d31A-4xj6A:
undetectable
4d31B-4xj6A:
undetectable		 4d31A-4xj6A:
21.06
4d31B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 4d31A-4xj6A:
undetectable
4d31B-4xj6A:
undetectable		 4d31A-4xj6A:
21.06
4d31B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4d31A-4xj6A:
undetectable
4d31B-4xj6A:
undetectable		 4d31A-4xj6A:
21.06
4d31B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4d31A-4xj6A:
undetectable
4d31B-4xj6A:
undetectable		 4d31A-4xj6A:
21.06
4d31B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 4d32A-4xj6A:
undetectable
4d32B-4xj6A:
undetectable		 4d32A-4xj6A:
21.06
4d32B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 4d32A-4xj6A:
undetectable
4d32B-4xj6A:
undetectable		 4d32A-4xj6A:
21.06
4d32B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.22A 4d32A-4xj6A:
undetectable
4d32B-4xj6A:
undetectable		 4d32A-4xj6A:
21.06
4d32B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4d32A-4xj6A:
undetectable
4d32B-4xj6A:
undetectable		 4d32A-4xj6A:
21.06
4d32B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4d3bA-4xj6A:
undetectable
4d3bB-4xj6A:
undetectable		 4d3bA-4xj6A:
21.06
4d3bB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 4d3bA-4xj6A:
undetectable
4d3bB-4xj6A:
undetectable		 4d3bA-4xj6A:
21.06
4d3bB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 4d3bA-4xj6A:
undetectable
4d3bB-4xj6A:
undetectable		 4d3bA-4xj6A:
21.06
4d3bB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.05A 4d3bA-4xj6A:
undetectable
4d3bB-4xj6A:
undetectable		 4d3bA-4xj6A:
21.06
4d3bB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4d7oA-4xj6A:
undetectable
4d7oB-4xj6A:
2.1		 4d7oA-4xj6A:
21.06
4d7oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4d7oA-4xj6A:
undetectable
4d7oB-4xj6A:
2.1		 4d7oA-4xj6A:
21.06
4d7oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4d7oA-4xj6A:
undetectable
4d7oB-4xj6A:
2.1		 4d7oA-4xj6A:
21.06
4d7oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4d7oA-4xj6A:
undetectable
4d7oB-4xj6A:
2.1		 4d7oA-4xj6A:
21.06
4d7oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4euxA-4xj6A:
undetectable
4euxB-4xj6A:
undetectable		 4euxA-4xj6A:
21.06
4euxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4euxA-4xj6A:
undetectable
4euxB-4xj6A:
undetectable		 4euxA-4xj6A:
21.06
4euxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 4euxA-4xj6A:
undetectable
4euxB-4xj6A:
undetectable		 4euxA-4xj6A:
21.06
4euxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4euxA-4xj6A:
undetectable
4euxB-4xj6A:
undetectable		 4euxA-4xj6A:
21.06
4euxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4fvwA-4xj6A:
undetectable
4fvwB-4xj6A:
undetectable		 4fvwA-4xj6A:
21.06
4fvwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4fvwA-4xj6A:
undetectable
4fvwB-4xj6A:
undetectable		 4fvwA-4xj6A:
21.06
4fvwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4fvwA-4xj6A:
undetectable
4fvwB-4xj6A:
undetectable		 4fvwA-4xj6A:
21.06
4fvwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4fvwA-4xj6A:
undetectable
4fvwB-4xj6A:
undetectable		 4fvwA-4xj6A:
21.06
4fvwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4fvxA-4xj6A:
undetectable
4fvxB-4xj6A:
undetectable		 4fvxA-4xj6A:
21.06
4fvxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4fvxA-4xj6A:
undetectable
4fvxB-4xj6A:
undetectable		 4fvxA-4xj6A:
21.06
4fvxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4fvxA-4xj6A:
undetectable
4fvxB-4xj6A:
undetectable		 4fvxA-4xj6A:
21.06
4fvxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 4fvxA-4xj6A:
undetectable
4fvxB-4xj6A:
undetectable		 4fvxA-4xj6A:
21.06
4fvxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4fvyA-4xj6A:
undetectable
4fvyB-4xj6A:
undetectable		 4fvyA-4xj6A:
21.06
4fvyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4fvyA-4xj6A:
undetectable
4fvyB-4xj6A:
undetectable		 4fvyA-4xj6A:
21.06
4fvyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4fvyA-4xj6A:
undetectable
4fvyB-4xj6A:
undetectable		 4fvyA-4xj6A:
21.06
4fvyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4fvyA-4xj6A:
undetectable
4fvyB-4xj6A:
undetectable		 4fvyA-4xj6A:
21.06
4fvyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.16A 4fvzA-4xj6A:
undetectable
4fvzB-4xj6A:
1.8		 4fvzA-4xj6A:
21.06
4fvzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 4fvzA-4xj6A:
undetectable
4fvzB-4xj6A:
1.8		 4fvzA-4xj6A:
21.06
4fvzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 4fvzA-4xj6A:
undetectable
4fvzB-4xj6A:
1.8		 4fvzA-4xj6A:
21.06
4fvzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 4fvzA-4xj6A:
undetectable
4fvzB-4xj6A:
1.8		 4fvzA-4xj6A:
21.06
4fvzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 4fw0A-4xj6A:
undetectable
4fw0B-4xj6A:
undetectable		 4fw0A-4xj6A:
21.06
4fw0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4fw0A-4xj6A:
undetectable
4fw0B-4xj6A:
undetectable		 4fw0A-4xj6A:
21.06
4fw0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4fw0A-4xj6A:
undetectable
4fw0B-4xj6A:
undetectable		 4fw0A-4xj6A:
21.06
4fw0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 4fw0A-4xj6A:
undetectable
4fw0B-4xj6A:
undetectable		 4fw0A-4xj6A:
21.06
4fw0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4gqeA-4xj6A:
undetectable
4gqeB-4xj6A:
undetectable		 4gqeA-4xj6A:
21.06
4gqeB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4gqeA-4xj6A:
undetectable
4gqeB-4xj6A:
undetectable		 4gqeA-4xj6A:
21.06
4gqeB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 4gqeA-4xj6A:
undetectable
4gqeB-4xj6A:
undetectable		 4gqeA-4xj6A:
21.06
4gqeB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4gqeA-4xj6A:
undetectable
4gqeB-4xj6A:
undetectable		 4gqeA-4xj6A:
21.06
4gqeB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 4imtA-4xj6A:
undetectable
4imtB-4xj6A:
undetectable		 4imtA-4xj6A:
21.06
4imtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 4imtA-4xj6A:
undetectable
4imtB-4xj6A:
undetectable		 4imtA-4xj6A:
21.06
4imtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.23A 4imtA-4xj6A:
undetectable
4imtB-4xj6A:
undetectable		 4imtA-4xj6A:
21.06
4imtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 4imtA-4xj6A:
undetectable
4imtB-4xj6A:
undetectable		 4imtA-4xj6A:
21.06
4imtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 4imuA-4xj6A:
undetectable
4imuB-4xj6A:
undetectable		 4imuA-4xj6A:
21.06
4imuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4imuA-4xj6A:
undetectable
4imuB-4xj6A:
undetectable		 4imuA-4xj6A:
21.06
4imuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 4imwA-4xj6A:
0.1
4imwB-4xj6A:
2.1		 4imwA-4xj6A:
21.06
4imwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.14A 4imwA-4xj6A:
0.1
4imwB-4xj6A:
2.1		 4imwA-4xj6A:
21.06
4imwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4imwA-4xj6A:
0.1
4imwB-4xj6A:
undetectable		 4imwA-4xj6A:
21.06
4imwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.14A 4imwA-4xj6A:
0.1
4imwB-4xj6A:
undetectable		 4imwA-4xj6A:
21.06
4imwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.15A 4jseA-4xj6A:
undetectable
4jseB-4xj6A:
2.1		 4jseA-4xj6A:
21.06
4jseB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.14A 4jseA-4xj6A:
undetectable
4jseB-4xj6A:
2.1		 4jseA-4xj6A:
21.06
4jseB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.05A 4jsfA-4xj6A:
undetectable
4jsfB-4xj6A:
undetectable		 4jsfA-4xj6A:
21.06
4jsfB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.15A 4jsfA-4xj6A:
undetectable
4jsfB-4xj6A:
undetectable		 4jsfA-4xj6A:
21.06
4jsfB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4jsfA-4xj6A:
undetectable
4jsfB-4xj6A:
undetectable		 4jsfA-4xj6A:
21.06
4jsfB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 4jsfA-4xj6A:
undetectable
4jsfB-4xj6A:
undetectable		 4jsfA-4xj6A:
21.06
4jsfB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 4jsgA-4xj6A:
undetectable
4jsgB-4xj6A:
undetectable		 4jsgA-4xj6A:
21.06
4jsgB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 4jsgA-4xj6A:
undetectable
4jsgB-4xj6A:
undetectable		 4jsgA-4xj6A:
21.06
4jsgB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.11A 4jsgA-4xj6A:
undetectable
4jsgB-4xj6A:
undetectable		 4jsgA-4xj6A:
21.06
4jsgB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4jsgA-4xj6A:
undetectable
4jsgB-4xj6A:
undetectable		 4jsgA-4xj6A:
21.06
4jsgB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 4jshA-4xj6A:
undetectable
4jshB-4xj6A:
undetectable		 4jshA-4xj6A:
21.06
4jshB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4jshA-4xj6A:
undetectable
4jshB-4xj6A:
undetectable		 4jshA-4xj6A:
21.06
4jshB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 4jshA-4xj6A:
undetectable
4jshB-4xj6A:
undetectable		 4jshA-4xj6A:
21.06
4jshB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.16A 4jshA-4xj6A:
undetectable
4jshB-4xj6A:
undetectable		 4jshA-4xj6A:
21.06
4jshB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 4jsiA-4xj6A:
undetectable
4jsiB-4xj6A:
undetectable		 4jsiA-4xj6A:
21.06
4jsiB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 4jsiA-4xj6A:
undetectable
4jsiB-4xj6A:
undetectable		 4jsiA-4xj6A:
21.06
4jsiB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4jsiA-4xj6A:
undetectable
4jsiB-4xj6A:
undetectable		 4jsiA-4xj6A:
21.06
4jsiB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 4jsiA-4xj6A:
undetectable
4jsiB-4xj6A:
undetectable		 4jsiA-4xj6A:
21.06
4jsiB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 4jsjA-4xj6A:
undetectable
4jsjB-4xj6A:
2.1		 4jsjA-4xj6A:
21.06
4jsjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4jsjA-4xj6A:
undetectable
4jsjB-4xj6A:
2.1		 4jsjA-4xj6A:
21.06
4jsjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4jsjA-4xj6A:
undetectable
4jsjB-4xj6A:
2.0		 4jsjA-4xj6A:
21.06
4jsjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4jsjA-4xj6A:
undetectable
4jsjB-4xj6A:
2.0		 4jsjA-4xj6A:
21.06
4jsjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4k5dA-4xj6A:
undetectable
4k5dB-4xj6A:
undetectable		 4k5dA-4xj6A:
21.06
4k5dB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4k5dA-4xj6A:
undetectable
4k5dB-4xj6A:
undetectable		 4k5dA-4xj6A:
21.06
4k5dB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 4k5dA-4xj6A:
undetectable
4k5dB-4xj6A:
undetectable		 4k5dA-4xj6A:
21.06
4k5dB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4k5dA-4xj6A:
undetectable
4k5dB-4xj6A:
undetectable		 4k5dA-4xj6A:
21.06
4k5dB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 4k5eA-4xj6A:
undetectable
4k5eB-4xj6A:
1.7		 4k5eA-4xj6A:
21.06
4k5eB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4k5eA-4xj6A:
undetectable
4k5eB-4xj6A:
1.7		 4k5eA-4xj6A:
21.06
4k5eB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4k5eA-4xj6A:
undetectable
4k5eB-4xj6A:
1.7		 4k5eA-4xj6A:
21.06
4k5eB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4k5eA-4xj6A:
undetectable
4k5eB-4xj6A:
1.7		 4k5eA-4xj6A:
21.06
4k5eB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 4k5fA-4xj6A:
1.6
4k5fB-4xj6A:
undetectable		 4k5fA-4xj6A:
21.06
4k5fB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4k5fA-4xj6A:
1.6
4k5fB-4xj6A:
undetectable		 4k5fA-4xj6A:
21.06
4k5fB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4k5fA-4xj6A:
1.7
4k5fB-4xj6A:
undetectable		 4k5fA-4xj6A:
21.06
4k5fB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 4k5fA-4xj6A:
1.7
4k5fB-4xj6A:
undetectable		 4k5fA-4xj6A:
21.06
4k5fB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4k5gA-4xj6A:
undetectable
4k5gB-4xj6A:
undetectable		 4k5gA-4xj6A:
21.06
4k5gB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 4k5gA-4xj6A:
undetectable
4k5gB-4xj6A:
undetectable		 4k5gA-4xj6A:
21.06
4k5gB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4k5gA-4xj6A:
undetectable
4k5gB-4xj6A:
undetectable		 4k5gA-4xj6A:
21.06
4k5gB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4k5gA-4xj6A:
undetectable
4k5gB-4xj6A:
undetectable		 4k5gA-4xj6A:
21.06
4k5gB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4kchA-4xj6A:
undetectable
4kchB-4xj6A:
undetectable		 4kchA-4xj6A:
21.06
4kchB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 4kchA-4xj6A:
undetectable
4kchB-4xj6A:
undetectable		 4kchA-4xj6A:
21.06
4kchB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4kchA-4xj6A:
undetectable
4kchB-4xj6A:
undetectable		 4kchA-4xj6A:
21.06
4kchB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 4kchA-4xj6A:
undetectable
4kchB-4xj6A:
undetectable		 4kchA-4xj6A:
21.06
4kchB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4kciA-4xj6A:
undetectable
4kciB-4xj6A:
undetectable		 4kciA-4xj6A:
21.06
4kciB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4kciA-4xj6A:
undetectable
4kciB-4xj6A:
undetectable		 4kciA-4xj6A:
21.06
4kciB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 4kciA-4xj6A:
undetectable
4kciB-4xj6A:
undetectable		 4kciA-4xj6A:
21.06
4kciB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 4kciA-4xj6A:
undetectable
4kciB-4xj6A:
undetectable		 4kciA-4xj6A:
21.06
4kciB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4kcjA-4xj6A:
1.6
4kcjB-4xj6A:
undetectable		 4kcjA-4xj6A:
21.06
4kcjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4kcjA-4xj6A:
1.6
4kcjB-4xj6A:
undetectable		 4kcjA-4xj6A:
21.06
4kcjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 4kcjA-4xj6A:
1.7
4kcjB-4xj6A:
undetectable		 4kcjA-4xj6A:
21.06
4kcjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 4kcjA-4xj6A:
1.7
4kcjB-4xj6A:
undetectable		 4kcjA-4xj6A:
21.06
4kcjB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4kckA-4xj6A:
undetectable
4kckB-4xj6A:
undetectable		 4kckA-4xj6A:
21.06
4kckB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 4kckA-4xj6A:
undetectable
4kckB-4xj6A:
undetectable		 4kckA-4xj6A:
21.06
4kckB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4kckA-4xj6A:
undetectable
4kckB-4xj6A:
undetectable		 4kckA-4xj6A:
21.06
4kckB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4kckA-4xj6A:
undetectable
4kckB-4xj6A:
undetectable		 4kckA-4xj6A:
21.06
4kckB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4kclA-4xj6A:
undetectable
4kclB-4xj6A:
2.0		 4kclA-4xj6A:
21.06
4kclB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4kclA-4xj6A:
undetectable
4kclB-4xj6A:
2.0		 4kclA-4xj6A:
21.06
4kclB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4kclA-4xj6A:
undetectable
4kclB-4xj6A:
undetectable		 4kclA-4xj6A:
21.06
4kclB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4kclA-4xj6A:
undetectable
4kclB-4xj6A:
undetectable		 4kclA-4xj6A:
21.06
4kclB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4kcmA-4xj6A:
undetectable
4kcmB-4xj6A:
1.7		 4kcmA-4xj6A:
21.06
4kcmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 4kcmA-4xj6A:
undetectable
4kcmB-4xj6A:
1.7		 4kcmA-4xj6A:
21.06
4kcmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 4kcmA-4xj6A:
undetectable
4kcmB-4xj6A:
1.7		 4kcmA-4xj6A:
21.06
4kcmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4kcmA-4xj6A:
undetectable
4kcmB-4xj6A:
1.7		 4kcmA-4xj6A:
21.06
4kcmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4kcnA-4xj6A:
undetectable
4kcnB-4xj6A:
undetectable		 4kcnA-4xj6A:
21.06
4kcnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4kcnA-4xj6A:
undetectable
4kcnB-4xj6A:
undetectable		 4kcnA-4xj6A:
21.06
4kcnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4kcnA-4xj6A:
undetectable
4kcnB-4xj6A:
undetectable		 4kcnA-4xj6A:
21.06
4kcnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 4kcnA-4xj6A:
undetectable
4kcnB-4xj6A:
undetectable		 4kcnA-4xj6A:
21.06
4kcnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4kcoA-4xj6A:
undetectable
4kcoB-4xj6A:
undetectable		 4kcoA-4xj6A:
21.06
4kcoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4kcoA-4xj6A:
undetectable
4kcoB-4xj6A:
undetectable		 4kcoA-4xj6A:
21.06
4kcoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 4kcoA-4xj6A:
undetectable
4kcoB-4xj6A:
undetectable		 4kcoA-4xj6A:
21.06
4kcoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4kcoA-4xj6A:
undetectable
4kcoB-4xj6A:
undetectable		 4kcoA-4xj6A:
21.06
4kcoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 4luxA-4xj6A:
undetectable
4luxB-4xj6A:
undetectable		 4luxA-4xj6A:
21.06
4luxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4luxA-4xj6A:
undetectable
4luxB-4xj6A:
undetectable		 4luxA-4xj6A:
21.06
4luxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4luxA-4xj6A:
undetectable
4luxB-4xj6A:
undetectable		 4luxA-4xj6A:
21.06
4luxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4luxA-4xj6A:
undetectable
4luxB-4xj6A:
undetectable		 4luxA-4xj6A:
21.06
4luxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
ILE A 271
 None
 1.28A 4nosA-4xj6A:
undetectable
4nosB-4xj6A:
undetectable		 4nosA-4xj6A:
23.14
4nosB-4xj6A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
ILE A 271
PHE A 264
GLU A 266
 None
 1.27A 4nosC-4xj6A:
undetectable
4nosD-4xj6A:
undetectable		 4nosC-4xj6A:
23.14
4nosD-4xj6A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
ILE A 271
 None
 1.34A 4nosC-4xj6A:
undetectable
4nosD-4xj6A:
undetectable		 4nosC-4xj6A:
23.14
4nosD-4xj6A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 9 TYR A   9
ALA A 376
ILE A 372
PHE A 393
ILE A 389
 None
 1.46A 4oknB-4xj6A:
undetectable		 4oknB-4xj6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		3 / 3 ASP A 131
ASP A 129
ASN A 119
 MG  A 501 ( 2.5A)
MG  A 502 (-2.2A)
None
 0.72A 4q5mA-4xj6A:
undetectable		 4q5mA-4xj6A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 4uchA-4xj6A:
undetectable
4uchB-4xj6A:
undetectable		 4uchA-4xj6A:
20.37
4uchB-4xj6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 4uchA-4xj6A:
undetectable
4uchB-4xj6A:
undetectable		 4uchA-4xj6A:
20.37
4uchB-4xj6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 4uchA-4xj6A:
undetectable
4uchB-4xj6A:
undetectable		 4uchA-4xj6A:
20.37
4uchB-4xj6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4uchA-4xj6A:
undetectable
4uchB-4xj6A:
undetectable		 4uchA-4xj6A:
20.37
4uchB-4xj6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4ugzA-4xj6A:
undetectable
4ugzB-4xj6A:
undetectable		 4ugzA-4xj6A:
21.06
4ugzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 4ugzA-4xj6A:
undetectable
4ugzB-4xj6A:
undetectable		 4ugzA-4xj6A:
21.06
4ugzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 4ugzA-4xj6A:
undetectable
4ugzB-4xj6A:
undetectable		 4ugzA-4xj6A:
21.06
4ugzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 4ugzA-4xj6A:
undetectable
4ugzB-4xj6A:
undetectable		 4ugzA-4xj6A:
21.06
4ugzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 4uh0A-4xj6A:
undetectable
4uh0B-4xj6A:
undetectable		 4uh0A-4xj6A:
21.06
4uh0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 4uh0A-4xj6A:
undetectable
4uh0B-4xj6A:
undetectable		 4uh0A-4xj6A:
21.06
4uh0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 4uh0A-4xj6A:
undetectable
4uh0B-4xj6A:
undetectable		 4uh0A-4xj6A:
21.06
4uh0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4uh0A-4xj6A:
undetectable
4uh0B-4xj6A:
undetectable		 4uh0A-4xj6A:
21.06
4uh0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4uh1A-4xj6A:
undetectable
4uh1B-4xj6A:
undetectable		 4uh1A-4xj6A:
21.06
4uh1B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4uh1A-4xj6A:
undetectable
4uh1B-4xj6A:
undetectable		 4uh1A-4xj6A:
21.06
4uh1B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4uh1A-4xj6A:
undetectable
4uh1B-4xj6A:
undetectable		 4uh1A-4xj6A:
21.06
4uh1B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4uh1A-4xj6A:
undetectable
4uh1B-4xj6A:
undetectable		 4uh1A-4xj6A:
21.06
4uh1B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 4uh2A-4xj6A:
undetectable
4uh2B-4xj6A:
undetectable		 4uh2A-4xj6A:
21.06
4uh2B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 4uh2A-4xj6A:
undetectable
4uh2B-4xj6A:
undetectable		 4uh2A-4xj6A:
21.06
4uh2B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 4uh2A-4xj6A:
undetectable
4uh2B-4xj6A:
undetectable		 4uh2A-4xj6A:
21.06
4uh2B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4uh2A-4xj6A:
undetectable
4uh2B-4xj6A:
undetectable		 4uh2A-4xj6A:
21.06
4uh2B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4uh3A-4xj6A:
undetectable
4uh3B-4xj6A:
1.6		 4uh3A-4xj6A:
21.06
4uh3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 4uh3A-4xj6A:
undetectable
4uh3B-4xj6A:
1.6		 4uh3A-4xj6A:
21.06
4uh3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 4uh3A-4xj6A:
undetectable
4uh3B-4xj6A:
1.6		 4uh3A-4xj6A:
21.06
4uh3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 4uh3A-4xj6A:
undetectable
4uh3B-4xj6A:
1.6		 4uh3A-4xj6A:
21.06
4uh3B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4uh4A-4xj6A:
undetectable
4uh4B-4xj6A:
undetectable		 4uh4A-4xj6A:
21.06
4uh4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 4uh4A-4xj6A:
undetectable
4uh4B-4xj6A:
undetectable		 4uh4A-4xj6A:
21.06
4uh4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4uh4A-4xj6A:
undetectable
4uh4B-4xj6A:
undetectable		 4uh4A-4xj6A:
21.06
4uh4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4uh4A-4xj6A:
undetectable
4uh4B-4xj6A:
undetectable		 4uh4A-4xj6A:
21.06
4uh4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 4uh5A-4xj6A:
undetectable
4uh5B-4xj6A:
undetectable		 4uh5A-4xj6A:
20.42
4uh5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.05A 4uh5A-4xj6A:
undetectable
4uh5B-4xj6A:
undetectable		 4uh5A-4xj6A:
20.42
4uh5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 4uh5A-4xj6A:
undetectable
4uh5B-4xj6A:
undetectable		 4uh5A-4xj6A:
20.42
4uh5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 4uh5A-4xj6A:
undetectable
4uh5B-4xj6A:
undetectable		 4uh5A-4xj6A:
20.42
4uh5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4uh6A-4xj6A:
undetectable
4uh6B-4xj6A:
2.2		 4uh6A-4xj6A:
20.42
4uh6B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 4uh6A-4xj6A:
undetectable
4uh6B-4xj6A:
2.2		 4uh6A-4xj6A:
20.42
4uh6B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 4uh6A-4xj6A:
undetectable
4uh6B-4xj6A:
2.2		 4uh6A-4xj6A:
20.42
4uh6B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4uh6A-4xj6A:
undetectable
4uh6B-4xj6A:
2.2		 4uh6A-4xj6A:
20.42
4uh6B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 4upmA-4xj6A:
undetectable
4upmB-4xj6A:
undetectable		 4upmA-4xj6A:
21.06
4upmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4upmA-4xj6A:
undetectable
4upmB-4xj6A:
undetectable		 4upmA-4xj6A:
21.06
4upmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4upmA-4xj6A:
undetectable
4upmB-4xj6A:
undetectable		 4upmA-4xj6A:
21.06
4upmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 4upmA-4xj6A:
undetectable
4upmB-4xj6A:
undetectable		 4upmA-4xj6A:
21.06
4upmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.18A 4upnA-4xj6A:
undetectable
4upnB-4xj6A:
undetectable		 4upnA-4xj6A:
21.06
4upnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 4upnA-4xj6A:
undetectable
4upnB-4xj6A:
undetectable		 4upnA-4xj6A:
21.06
4upnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 4upnA-4xj6A:
undetectable
4upnB-4xj6A:
undetectable		 4upnA-4xj6A:
21.06
4upnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4upnA-4xj6A:
undetectable
4upnB-4xj6A:
undetectable		 4upnA-4xj6A:
21.06
4upnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4upoA-4xj6A:
undetectable
4upoB-4xj6A:
undetectable		 4upoA-4xj6A:
21.06
4upoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4upoA-4xj6A:
undetectable
4upoB-4xj6A:
undetectable		 4upoA-4xj6A:
21.06
4upoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 4upoA-4xj6A:
undetectable
4upoB-4xj6A:
undetectable		 4upoA-4xj6A:
21.06
4upoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 4upoA-4xj6A:
undetectable
4upoB-4xj6A:
undetectable		 4upoA-4xj6A:
21.06
4upoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4uppA-4xj6A:
undetectable
4uppB-4xj6A:
undetectable		 4uppA-4xj6A:
21.06
4uppB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 4uppA-4xj6A:
undetectable
4uppB-4xj6A:
undetectable		 4uppA-4xj6A:
21.06
4uppB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4uppA-4xj6A:
undetectable
4uppB-4xj6A:
undetectable		 4uppA-4xj6A:
21.06
4uppB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 4uppA-4xj6A:
undetectable
4uppB-4xj6A:
undetectable		 4uppA-4xj6A:
21.06
4uppB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 4v3uA-4xj6A:
undetectable
4v3uB-4xj6A:
undetectable		 4v3uA-4xj6A:
19.92
4v3uB-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.05A 4v3uA-4xj6A:
undetectable
4v3uB-4xj6A:
undetectable		 4v3uA-4xj6A:
19.92
4v3uB-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 4v3uA-4xj6A:
undetectable
4v3uB-4xj6A:
undetectable		 4v3uA-4xj6A:
19.92
4v3uB-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.06A 4v3uA-4xj6A:
undetectable
4v3uB-4xj6A:
undetectable		 4v3uA-4xj6A:
19.92
4v3uB-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 4v3uC-4xj6A:
undetectable
4v3uD-4xj6A:
undetectable		 4v3uC-4xj6A:
19.92
4v3uD-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.02A 4v3uC-4xj6A:
undetectable
4v3uD-4xj6A:
undetectable		 4v3uC-4xj6A:
19.92
4v3uD-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 4v3uC-4xj6A:
undetectable
4v3uD-4xj6A:
undetectable		 4v3uC-4xj6A:
19.92
4v3uD-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 4v3uC-4xj6A:
undetectable
4v3uD-4xj6A:
undetectable		 4v3uC-4xj6A:
19.92
4v3uD-4xj6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 4v3vA-4xj6A:
1.7
4v3vB-4xj6A:
undetectable		 4v3vA-4xj6A:
21.06
4v3vB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 4v3vA-4xj6A:
1.7
4v3vB-4xj6A:
undetectable		 4v3vA-4xj6A:
21.06
4v3vB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 4v3vA-4xj6A:
1.6
4v3vB-4xj6A:
undetectable		 4v3vA-4xj6A:
21.06
4v3vB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.06A 4v3vA-4xj6A:
1.6
4v3vB-4xj6A:
undetectable		 4v3vA-4xj6A:
21.06
4v3vB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.14A 4v3wA-4xj6A:
2.0
4v3wB-4xj6A:
undetectable		 4v3wA-4xj6A:
21.06
4v3wB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.08A 4v3wA-4xj6A:
undetectable
4v3wB-4xj6A:
undetectable		 4v3wA-4xj6A:
21.06
4v3wB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 4v3wA-4xj6A:
undetectable
4v3wB-4xj6A:
undetectable		 4v3wA-4xj6A:
21.06
4v3wB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 4v3xA-4xj6A:
undetectable
4v3xB-4xj6A:
undetectable		 4v3xA-4xj6A:
21.06
4v3xB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 4v3xA-4xj6A:
undetectable
4v3xB-4xj6A:
undetectable		 4v3xA-4xj6A:
21.06
4v3xB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 4v3xA-4xj6A:
undetectable
4v3xB-4xj6A:
undetectable		 4v3xA-4xj6A:
21.06
4v3xB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 4v3xA-4xj6A:
undetectable
4v3xB-4xj6A:
undetectable		 4v3xA-4xj6A:
21.06
4v3xB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 4v3yA-4xj6A:
undetectable
4v3yB-4xj6A:
1.7		 4v3yA-4xj6A:
21.06
4v3yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 4v3yA-4xj6A:
undetectable
4v3yB-4xj6A:
1.7		 4v3yA-4xj6A:
21.06
4v3yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 4v3yA-4xj6A:
undetectable
4v3yB-4xj6A:
1.7		 4v3yA-4xj6A:
21.06
4v3yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 4v3yA-4xj6A:
undetectable
4v3yB-4xj6A:
1.7		 4v3yA-4xj6A:
21.06
4v3yB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.16A 4v3zA-4xj6A:
undetectable
4v3zB-4xj6A:
undetectable		 4v3zA-4xj6A:
21.06
4v3zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 4v3zA-4xj6A:
undetectable
4v3zB-4xj6A:
undetectable		 4v3zA-4xj6A:
21.06
4v3zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.23A 4v3zA-4xj6A:
undetectable
4v3zB-4xj6A:
undetectable		 4v3zA-4xj6A:
21.06
4v3zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 4v3zA-4xj6A:
undetectable
4v3zB-4xj6A:
undetectable		 4v3zA-4xj6A:
21.06
4v3zB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 12 ALA A 303
LEU A 300
LEU A 329
LEU A 328
PRO A 295
 None
 0.93A 4xi3D-4xj6A:
2.5		 4xi3D-4xj6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.01A 5ad4A-4xj6A:
undetectable
5ad4B-4xj6A:
undetectable		 5ad4A-4xj6A:
21.06
5ad4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.13A 5ad4A-4xj6A:
undetectable
5ad4B-4xj6A:
undetectable		 5ad4A-4xj6A:
21.06
5ad4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 5ad4A-4xj6A:
undetectable
5ad4B-4xj6A:
undetectable		 5ad4A-4xj6A:
21.06
5ad4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.18A 5ad4A-4xj6A:
undetectable
5ad4B-4xj6A:
undetectable		 5ad4A-4xj6A:
21.06
5ad4B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 5ad5A-4xj6A:
undetectable
5ad5B-4xj6A:
2.2		 5ad5A-4xj6A:
21.06
5ad5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.15A 5ad5A-4xj6A:
undetectable
5ad5B-4xj6A:
2.2		 5ad5A-4xj6A:
21.06
5ad5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5ad5A-4xj6A:
undetectable
5ad5B-4xj6A:
2.2		 5ad5A-4xj6A:
21.06
5ad5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 5ad5A-4xj6A:
undetectable
5ad5B-4xj6A:
2.2		 5ad5A-4xj6A:
21.06
5ad5B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5ad6A-4xj6A:
undetectable
5ad6B-4xj6A:
1.6		 5ad6A-4xj6A:
21.06
5ad6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5ad6A-4xj6A:
undetectable
5ad6B-4xj6A:
1.6		 5ad6A-4xj6A:
21.06
5ad6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5ad6A-4xj6A:
undetectable
5ad6B-4xj6A:
1.6		 5ad6A-4xj6A:
21.06
5ad6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 5ad6A-4xj6A:
undetectable
5ad6B-4xj6A:
1.6		 5ad6A-4xj6A:
21.06
5ad6B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 5ad7A-4xj6A:
undetectable
5ad7B-4xj6A:
1.7		 5ad7A-4xj6A:
21.06
5ad7B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5ad7A-4xj6A:
undetectable
5ad7B-4xj6A:
1.7		 5ad7A-4xj6A:
21.06
5ad7B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5ad8A-4xj6A:
undetectable
5ad8B-4xj6A:
1.7		 5ad8A-4xj6A:
21.06
5ad8B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 5ad8A-4xj6A:
undetectable
5ad8B-4xj6A:
1.7		 5ad8A-4xj6A:
21.06
5ad8B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.20A 5ad9A-4xj6A:
undetectable
5ad9B-4xj6A:
undetectable		 5ad9A-4xj6A:
21.06
5ad9B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 5ad9A-4xj6A:
undetectable
5ad9B-4xj6A:
undetectable		 5ad9A-4xj6A:
21.06
5ad9B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.29A 5ad9A-4xj6A:
undetectable
5ad9B-4xj6A:
undetectable		 5ad9A-4xj6A:
21.06
5ad9B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 5ad9A-4xj6A:
undetectable
5ad9B-4xj6A:
undetectable		 5ad9A-4xj6A:
21.06
5ad9B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 5adaA-4xj6A:
1.8
5adaB-4xj6A:
1.7		 5adaA-4xj6A:
21.06
5adaB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.14A 5adaA-4xj6A:
1.8
5adaB-4xj6A:
1.7		 5adaA-4xj6A:
21.06
5adaB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5adaA-4xj6A:
1.7
5adaB-4xj6A:
1.7		 5adaA-4xj6A:
21.06
5adaB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5adaA-4xj6A:
1.7
5adaB-4xj6A:
1.7		 5adaA-4xj6A:
21.06
5adaB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.22A 5adbA-4xj6A:
undetectable
5adbB-4xj6A:
undetectable		 5adbA-4xj6A:
21.06
5adbB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 5adbA-4xj6A:
undetectable
5adbB-4xj6A:
undetectable		 5adbA-4xj6A:
21.06
5adbB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 5adcA-4xj6A:
undetectable
5adcB-4xj6A:
undetectable		 5adcA-4xj6A:
21.06
5adcB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 5adcA-4xj6A:
undetectable
5adcB-4xj6A:
undetectable		 5adcA-4xj6A:
21.06
5adcB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 5adcA-4xj6A:
undetectable
5adcB-4xj6A:
undetectable		 5adcA-4xj6A:
21.06
5adcB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5adcA-4xj6A:
undetectable
5adcB-4xj6A:
undetectable		 5adcA-4xj6A:
21.06
5adcB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 5addA-4xj6A:
undetectable
5addB-4xj6A:
2.2		 5addA-4xj6A:
21.06
5addB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 5addA-4xj6A:
undetectable
5addB-4xj6A:
2.2		 5addA-4xj6A:
21.06
5addB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 5adeA-4xj6A:
undetectable
5adeB-4xj6A:
undetectable		 5adeA-4xj6A:
21.06
5adeB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 5adeA-4xj6A:
undetectable
5adeB-4xj6A:
undetectable		 5adeA-4xj6A:
21.06
5adeB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 5adfA-4xj6A:
undetectable
5adfB-4xj6A:
undetectable		 5adfA-4xj6A:
20.42
5adfB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 5adfA-4xj6A:
undetectable
5adfB-4xj6A:
undetectable		 5adfA-4xj6A:
20.42
5adfB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 5adgA-4xj6A:
undetectable
5adgB-4xj6A:
undetectable		 5adgA-4xj6A:
20.42
5adgB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 5adgA-4xj6A:
undetectable
5adgB-4xj6A:
undetectable		 5adgA-4xj6A:
20.42
5adgB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.11A 5adgA-4xj6A:
undetectable
5adgB-4xj6A:
undetectable		 5adgA-4xj6A:
20.42
5adgB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 5adgA-4xj6A:
undetectable
5adgB-4xj6A:
undetectable		 5adgA-4xj6A:
20.42
5adgB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.20A 5adiA-4xj6A:
undetectable
5adiB-4xj6A:
undetectable		 5adiA-4xj6A:
20.42
5adiB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5adiA-4xj6A:
undetectable
5adiB-4xj6A:
undetectable		 5adiA-4xj6A:
20.42
5adiB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 5agkA-4xj6A:
undetectable
5agkB-4xj6A:
undetectable		 5agkA-4xj6A:
21.06
5agkB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 5agkA-4xj6A:
undetectable
5agkB-4xj6A:
undetectable		 5agkA-4xj6A:
21.06
5agkB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5agkA-4xj6A:
undetectable
5agkB-4xj6A:
undetectable		 5agkA-4xj6A:
21.06
5agkB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 5agkA-4xj6A:
undetectable
5agkB-4xj6A:
undetectable		 5agkA-4xj6A:
21.06
5agkB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5aglA-4xj6A:
undetectable
5aglB-4xj6A:
undetectable		 5aglA-4xj6A:
21.06
5aglB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 5aglA-4xj6A:
undetectable
5aglB-4xj6A:
undetectable		 5aglA-4xj6A:
21.06
5aglB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 5aglA-4xj6A:
undetectable
5aglB-4xj6A:
undetectable		 5aglA-4xj6A:
21.06
5aglB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 5aglA-4xj6A:
undetectable
5aglB-4xj6A:
undetectable		 5aglA-4xj6A:
21.06
5aglB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 5agmA-4xj6A:
undetectable
5agmB-4xj6A:
undetectable		 5agmA-4xj6A:
21.06
5agmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 5agmA-4xj6A:
undetectable
5agmB-4xj6A:
undetectable		 5agmA-4xj6A:
21.06
5agmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5agmA-4xj6A:
undetectable
5agmB-4xj6A:
undetectable		 5agmA-4xj6A:
21.06
5agmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5agmA-4xj6A:
undetectable
5agmB-4xj6A:
undetectable		 5agmA-4xj6A:
21.06
5agmB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5agnA-4xj6A:
undetectable
5agnB-4xj6A:
undetectable		 5agnA-4xj6A:
21.06
5agnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 5agnA-4xj6A:
undetectable
5agnB-4xj6A:
undetectable		 5agnA-4xj6A:
21.06
5agnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5agnA-4xj6A:
undetectable
5agnB-4xj6A:
undetectable		 5agnA-4xj6A:
21.06
5agnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5agnA-4xj6A:
undetectable
5agnB-4xj6A:
undetectable		 5agnA-4xj6A:
21.06
5agnB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5agoA-4xj6A:
undetectable
5agoB-4xj6A:
undetectable		 5agoA-4xj6A:
21.06
5agoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5agoA-4xj6A:
undetectable
5agoB-4xj6A:
undetectable		 5agoA-4xj6A:
21.06
5agoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 5agoA-4xj6A:
undetectable
5agoB-4xj6A:
undetectable		 5agoA-4xj6A:
21.06
5agoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 5agoA-4xj6A:
undetectable
5agoB-4xj6A:
undetectable		 5agoA-4xj6A:
21.06
5agoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 5agpA-4xj6A:
undetectable
5agpB-4xj6A:
1.5		 5agpA-4xj6A:
21.06
5agpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 5agpA-4xj6A:
undetectable
5agpB-4xj6A:
1.5		 5agpA-4xj6A:
21.06
5agpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 5agpA-4xj6A:
undetectable
5agpB-4xj6A:
1.7		 5agpA-4xj6A:
21.06
5agpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5agpA-4xj6A:
undetectable
5agpB-4xj6A:
1.7		 5agpA-4xj6A:
21.06
5agpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 5fvpA-4xj6A:
2.1
5fvpB-4xj6A:
undetectable		 5fvpA-4xj6A:
21.06
5fvpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 5fvpA-4xj6A:
2.1
5fvpB-4xj6A:
undetectable		 5fvpA-4xj6A:
21.06
5fvpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.19A 5fvpA-4xj6A:
2.1
5fvpB-4xj6A:
undetectable		 5fvpA-4xj6A:
21.06
5fvpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.14A 5fvpA-4xj6A:
2.1
5fvpB-4xj6A:
undetectable		 5fvpA-4xj6A:
21.06
5fvpB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 5fvqA-4xj6A:
undetectable
5fvqB-4xj6A:
undetectable		 5fvqA-4xj6A:
21.06
5fvqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 5fvqA-4xj6A:
undetectable
5fvqB-4xj6A:
undetectable		 5fvqA-4xj6A:
21.06
5fvqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.11A 5fvqA-4xj6A:
undetectable
5fvqB-4xj6A:
undetectable		 5fvqA-4xj6A:
21.06
5fvqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 5fvqA-4xj6A:
undetectable
5fvqB-4xj6A:
undetectable		 5fvqA-4xj6A:
21.06
5fvqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 5fvrA-4xj6A:
undetectable
5fvrB-4xj6A:
undetectable		 5fvrA-4xj6A:
21.06
5fvrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 5fvrA-4xj6A:
undetectable
5fvrB-4xj6A:
undetectable		 5fvrA-4xj6A:
21.06
5fvrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.10A 5fvrA-4xj6A:
undetectable
5fvrB-4xj6A:
undetectable		 5fvrA-4xj6A:
21.06
5fvrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 5fvrA-4xj6A:
undetectable
5fvrB-4xj6A:
undetectable		 5fvrA-4xj6A:
21.06
5fvrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 5fvsA-4xj6A:
undetectable
5fvsB-4xj6A:
undetectable		 5fvsA-4xj6A:
21.06
5fvsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5fvsA-4xj6A:
undetectable
5fvsB-4xj6A:
undetectable		 5fvsA-4xj6A:
21.06
5fvsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 5fvsA-4xj6A:
undetectable
5fvsB-4xj6A:
undetectable		 5fvsA-4xj6A:
21.06
5fvsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.07A 5fvsA-4xj6A:
undetectable
5fvsB-4xj6A:
undetectable		 5fvsA-4xj6A:
21.06
5fvsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 5fvtA-4xj6A:
undetectable
5fvtB-4xj6A:
undetectable		 5fvtA-4xj6A:
21.06
5fvtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 5fvtA-4xj6A:
undetectable
5fvtB-4xj6A:
undetectable		 5fvtA-4xj6A:
21.06
5fvtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 5fvtA-4xj6A:
undetectable
5fvtB-4xj6A:
undetectable		 5fvtA-4xj6A:
21.06
5fvtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5fvtA-4xj6A:
undetectable
5fvtB-4xj6A:
undetectable		 5fvtA-4xj6A:
21.06
5fvtB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 5fvuA-4xj6A:
undetectable
5fvuB-4xj6A:
2.1		 5fvuA-4xj6A:
20.42
5fvuB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5fvuA-4xj6A:
undetectable
5fvuB-4xj6A:
2.1		 5fvuA-4xj6A:
20.42
5fvuB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 5fvuA-4xj6A:
undetectable
5fvuB-4xj6A:
undetectable		 5fvuA-4xj6A:
20.42
5fvuB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.14A 5fvuA-4xj6A:
undetectable
5fvuB-4xj6A:
undetectable		 5fvuA-4xj6A:
20.42
5fvuB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 5fvvA-4xj6A:
undetectable
5fvvB-4xj6A:
undetectable		 5fvvA-4xj6A:
20.42
5fvvB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 5fvvA-4xj6A:
undetectable
5fvvB-4xj6A:
undetectable		 5fvvA-4xj6A:
20.42
5fvvB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 5fvvA-4xj6A:
undetectable
5fvvB-4xj6A:
undetectable		 5fvvA-4xj6A:
20.42
5fvvB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5fvvA-4xj6A:
undetectable
5fvvB-4xj6A:
undetectable		 5fvvA-4xj6A:
20.42
5fvvB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.06A 5fvwA-4xj6A:
undetectable
5fvwB-4xj6A:
undetectable		 5fvwA-4xj6A:
20.42
5fvwB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.05A 5fvwA-4xj6A:
undetectable
5fvwB-4xj6A:
undetectable		 5fvwA-4xj6A:
20.42
5fvwB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.10A 5fvwA-4xj6A:
undetectable
5fvwB-4xj6A:
undetectable		 5fvwA-4xj6A:
20.42
5fvwB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5fvwA-4xj6A:
undetectable
5fvwB-4xj6A:
undetectable		 5fvwA-4xj6A:
20.42
5fvwB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 5fvxA-4xj6A:
undetectable
5fvxB-4xj6A:
2.2		 5fvxA-4xj6A:
20.42
5fvxB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 5fvxA-4xj6A:
undetectable
5fvxB-4xj6A:
2.2		 5fvxA-4xj6A:
20.42
5fvxB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 5fw0A-4xj6A:
1.7
5fw0B-4xj6A:
undetectable		 5fw0A-4xj6A:
21.06
5fw0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 5fw0A-4xj6A:
1.7
5fw0B-4xj6A:
undetectable		 5fw0A-4xj6A:
21.06
5fw0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 5fw0A-4xj6A:
1.7
5fw0B-4xj6A:
undetectable		 5fw0A-4xj6A:
21.06
5fw0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5fw0A-4xj6A:
1.7
5fw0B-4xj6A:
undetectable		 5fw0A-4xj6A:
21.06
5fw0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 5g0nA-4xj6A:
undetectable
5g0nB-4xj6A:
undetectable		 5g0nA-4xj6A:
21.06
5g0nB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5g0nA-4xj6A:
undetectable
5g0nB-4xj6A:
undetectable		 5g0nA-4xj6A:
21.06
5g0nB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5g0nA-4xj6A:
undetectable
5g0nB-4xj6A:
undetectable		 5g0nA-4xj6A:
21.06
5g0nB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 5g0nA-4xj6A:
undetectable
5g0nB-4xj6A:
undetectable		 5g0nA-4xj6A:
21.06
5g0nB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 5g0oA-4xj6A:
undetectable
5g0oB-4xj6A:
1.8		 5g0oA-4xj6A:
21.06
5g0oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 5g0oA-4xj6A:
undetectable
5g0oB-4xj6A:
1.8		 5g0oA-4xj6A:
21.06
5g0oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 5g0oA-4xj6A:
undetectable
5g0oB-4xj6A:
1.8		 5g0oA-4xj6A:
21.06
5g0oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5g0oA-4xj6A:
undetectable
5g0oB-4xj6A:
1.8		 5g0oA-4xj6A:
21.06
5g0oB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 5g0pA-4xj6A:
undetectable
5g0pB-4xj6A:
undetectable		 5g0pA-4xj6A:
21.06
5g0pB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 5g0pA-4xj6A:
undetectable
5g0pB-4xj6A:
undetectable		 5g0pA-4xj6A:
21.06
5g0pB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 5g0pA-4xj6A:
undetectable
5g0pB-4xj6A:
undetectable		 5g0pA-4xj6A:
21.06
5g0pB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.14A 5g0pA-4xj6A:
undetectable
5g0pB-4xj6A:
undetectable		 5g0pA-4xj6A:
21.06
5g0pB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 LEU A 151
ILE A  89
ALA A  52
PRO A 145
 None
 0.92A 5m0oC-4xj6A:
undetectable		 5m0oC-4xj6A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 333
CYH A 279
THR A 117
PHE A 264
 None
 1.42A 5mwyA-4xj6A:
3.4		 5mwyA-4xj6A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 12 PHE A  45
ILE A 147
PHE A 100
LEU A 153
VAL A 192
 None
 1.14A 5uanB-4xj6A:
undetectable		 5uanB-4xj6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5unrA-4xj6A:
1.7
5unrB-4xj6A:
undetectable		 5unrA-4xj6A:
21.06
5unrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5unrA-4xj6A:
1.7
5unrB-4xj6A:
undetectable		 5unrA-4xj6A:
21.06
5unrB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5unsA-4xj6A:
1.7
5unsB-4xj6A:
undetectable		 5unsA-4xj6A:
21.06
5unsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5unsA-4xj6A:
1.7
5unsB-4xj6A:
undetectable		 5unsA-4xj6A:
21.06
5unsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 5unsA-4xj6A:
1.7
5unsB-4xj6A:
undetectable		 5unsA-4xj6A:
21.06
5unsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5unsA-4xj6A:
1.7
5unsB-4xj6A:
undetectable		 5unsA-4xj6A:
21.06
5unsB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 5untA-4xj6A:
1.6
5untB-4xj6A:
2.1		 5untA-4xj6A:
21.06
5untB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 5untA-4xj6A:
1.6
5untB-4xj6A:
2.1		 5untA-4xj6A:
21.06
5untB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5untA-4xj6A:
1.6
5untB-4xj6A:
2.1		 5untA-4xj6A:
21.06
5untB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5untA-4xj6A:
1.6
5untB-4xj6A:
2.1		 5untA-4xj6A:
21.06
5untB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5unuA-4xj6A:
0.0
5unuB-4xj6A:
1.7		 5unuA-4xj6A:
21.06
5unuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.14A 5unuA-4xj6A:
0.0
5unuB-4xj6A:
1.7		 5unuA-4xj6A:
21.06
5unuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.23A 5unuA-4xj6A:
undetectable
5unuB-4xj6A:
1.7		 5unuA-4xj6A:
21.06
5unuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 5unuA-4xj6A:
undetectable
5unuB-4xj6A:
1.7		 5unuA-4xj6A:
21.06
5unuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 6 ARG A 276
VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.18A 5unvA-4xj6A:
0.1
5unvB-4xj6A:
undetectable		 5unvA-4xj6A:
21.06
5unvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.03A 5unvA-4xj6A:
0.1
5unvB-4xj6A:
undetectable		 5unvA-4xj6A:
21.06
5unvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.16A 5unvA-4xj6A:
0.1
5unvB-4xj6A:
undetectable		 5unvA-4xj6A:
21.06
5unvB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5unwA-4xj6A:
2.1
5unwB-4xj6A:
1.8		 5unwA-4xj6A:
21.06
5unwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5unwA-4xj6A:
2.1
5unwB-4xj6A:
1.8		 5unwA-4xj6A:
21.06
5unwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5unwA-4xj6A:
2.1
5unwB-4xj6A:
1.8		 5unwA-4xj6A:
21.06
5unwB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 5unxA-4xj6A:
2.2
5unxB-4xj6A:
undetectable		 5unxA-4xj6A:
21.06
5unxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 5unxA-4xj6A:
2.2
5unxB-4xj6A:
undetectable		 5unxA-4xj6A:
21.06
5unxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.27A 5unxA-4xj6A:
2.2
5unxB-4xj6A:
undetectable		 5unxA-4xj6A:
21.06
5unxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 5unxA-4xj6A:
2.2
5unxB-4xj6A:
undetectable		 5unxA-4xj6A:
21.06
5unxB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 5unyA-4xj6A:
undetectable
5unyB-4xj6A:
undetectable		 5unyA-4xj6A:
21.06
5unyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5unyA-4xj6A:
undetectable
5unyB-4xj6A:
undetectable		 5unyA-4xj6A:
21.06
5unyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 5unyA-4xj6A:
undetectable
5unyB-4xj6A:
undetectable		 5unyA-4xj6A:
21.06
5unyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 5unyA-4xj6A:
undetectable
5unyB-4xj6A:
undetectable		 5unyA-4xj6A:
21.06
5unyB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 5unzA-4xj6A:
undetectable
5unzB-4xj6A:
undetectable		 5unzA-4xj6A:
21.06
5unzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 5unzA-4xj6A:
undetectable
5unzB-4xj6A:
undetectable		 5unzA-4xj6A:
21.06
5unzB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 5uo0A-4xj6A:
2.1
5uo0B-4xj6A:
undetectable		 5uo0A-4xj6A:
21.06
5uo0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 5uo0A-4xj6A:
2.1
5uo0B-4xj6A:
undetectable		 5uo0A-4xj6A:
21.06
5uo0B-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.16A 5uo1A-4xj6A:
undetectable
5uo1B-4xj6A:
0.1		 5uo1A-4xj6A:
20.42
5uo1B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 5uo1A-4xj6A:
undetectable
5uo1B-4xj6A:
0.1		 5uo1A-4xj6A:
20.42
5uo1B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 5uo1A-4xj6A:
undetectable
5uo1B-4xj6A:
0.1		 5uo1A-4xj6A:
20.42
5uo1B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5uo1A-4xj6A:
undetectable
5uo1B-4xj6A:
0.1		 5uo1A-4xj6A:
20.42
5uo1B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.17A 5uo2A-4xj6A:
undetectable
5uo2B-4xj6A:
2.2		 5uo2A-4xj6A:
20.42
5uo2B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.14A 5uo2A-4xj6A:
undetectable
5uo2B-4xj6A:
2.2		 5uo2A-4xj6A:
20.42
5uo2B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5uo2A-4xj6A:
undetectable
5uo2B-4xj6A:
2.2		 5uo2A-4xj6A:
20.42
5uo2B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 5uo2A-4xj6A:
undetectable
5uo2B-4xj6A:
2.2		 5uo2A-4xj6A:
20.42
5uo2B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.18A 5uo3A-4xj6A:
undetectable
5uo3B-4xj6A:
undetectable		 5uo3A-4xj6A:
20.42
5uo3B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5uo3A-4xj6A:
undetectable
5uo3B-4xj6A:
undetectable		 5uo3A-4xj6A:
20.42
5uo3B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5uo3A-4xj6A:
undetectable
5uo3B-4xj6A:
undetectable		 5uo3A-4xj6A:
20.42
5uo3B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 5uo3A-4xj6A:
undetectable
5uo3B-4xj6A:
undetectable		 5uo3A-4xj6A:
20.42
5uo3B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 5uo4A-4xj6A:
undetectable
5uo4B-4xj6A:
undetectable		 5uo4A-4xj6A:
20.42
5uo4B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 5uo4A-4xj6A:
undetectable
5uo4B-4xj6A:
undetectable		 5uo4A-4xj6A:
20.42
5uo4B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 5uo4A-4xj6A:
undetectable
5uo4B-4xj6A:
undetectable		 5uo4A-4xj6A:
20.42
5uo4B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.13A 5uo4A-4xj6A:
undetectable
5uo4B-4xj6A:
undetectable		 5uo4A-4xj6A:
20.42
5uo4B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 5uo5A-4xj6A:
undetectable
5uo5B-4xj6A:
undetectable		 5uo5A-4xj6A:
20.42
5uo5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5uo5A-4xj6A:
undetectable
5uo5B-4xj6A:
undetectable		 5uo5A-4xj6A:
20.42
5uo5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 5uo5A-4xj6A:
0.5
5uo5B-4xj6A:
undetectable		 5uo5A-4xj6A:
20.42
5uo5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5uo5A-4xj6A:
0.5
5uo5B-4xj6A:
undetectable		 5uo5A-4xj6A:
20.42
5uo5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5uo6A-4xj6A:
undetectable
5uo6B-4xj6A:
undetectable		 5uo6A-4xj6A:
20.42
5uo6B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 5uo6A-4xj6A:
undetectable
5uo6B-4xj6A:
undetectable		 5uo6A-4xj6A:
20.42
5uo6B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.16A 5uo7A-4xj6A:
undetectable
5uo7B-4xj6A:
undetectable		 5uo7A-4xj6A:
20.42
5uo7B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 8 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5uo7A-4xj6A:
undetectable
5uo7B-4xj6A:
undetectable		 5uo7A-4xj6A:
20.42
5uo7B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 5uo7A-4xj6A:
undetectable
5uo7B-4xj6A:
undetectable		 5uo7A-4xj6A:
20.42
5uo7B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5uo7A-4xj6A:
undetectable
5uo7B-4xj6A:
undetectable		 5uo7A-4xj6A:
20.42
5uo7B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 5 LEU A 324
LYS A 323
ALA A 326
LEU A 329
LEU A 373
 None
 1.22A 5vkqA-4xj6A:
undetectable
5vkqD-4xj6A:
undetectable		 5vkqA-4xj6A:
12.73
5vkqD-4xj6A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 5 LEU A 373
LEU A 324
LYS A 323
ALA A 326
LEU A 329
 None
 1.19A 5vkqA-4xj6A:
undetectable
5vkqB-4xj6A:
undetectable		 5vkqA-4xj6A:
12.73
5vkqB-4xj6A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 5 LEU A 373
LEU A 324
LYS A 323
ALA A 326
LEU A 329
 None
 1.21A 5vkqB-4xj6A:
undetectable
5vkqC-4xj6A:
undetectable		 5vkqB-4xj6A:
12.73
5vkqC-4xj6A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 5 LEU A 373
LEU A 324
LYS A 323
ALA A 326
LEU A 329
 None
 1.19A 5vkqC-4xj6A:
undetectable
5vkqD-4xj6A:
undetectable		 5vkqC-4xj6A:
12.73
5vkqD-4xj6A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 5vuiA-4xj6A:
2.1
5vuiB-4xj6A:
2.1		 5vuiA-4xj6A:
21.06
5vuiB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 5vuiA-4xj6A:
2.1
5vuiB-4xj6A:
2.1		 5vuiA-4xj6A:
21.06
5vuiB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5vuiA-4xj6A:
2.1
5vuiB-4xj6A:
2.1		 5vuiA-4xj6A:
21.06
5vuiB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 5vuiA-4xj6A:
2.1
5vuiB-4xj6A:
2.1		 5vuiA-4xj6A:
21.06
5vuiB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 0.95A 5vujA-4xj6A:
1.6
5vujB-4xj6A:
undetectable		 5vujA-4xj6A:
21.06
5vujB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 5vujA-4xj6A:
1.6
5vujB-4xj6A:
undetectable		 5vujA-4xj6A:
21.06
5vujB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.06A 5vujA-4xj6A:
1.6
5vujB-4xj6A:
undetectable		 5vujA-4xj6A:
21.06
5vujB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5vujA-4xj6A:
1.6
5vujB-4xj6A:
undetectable		 5vujA-4xj6A:
21.06
5vujB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 5vukA-4xj6A:
undetectable
5vukB-4xj6A:
undetectable		 5vukA-4xj6A:
21.06
5vukB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5vukA-4xj6A:
undetectable
5vukB-4xj6A:
undetectable		 5vukA-4xj6A:
21.06
5vukB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5vukA-4xj6A:
undetectable
5vukB-4xj6A:
undetectable		 5vukA-4xj6A:
21.06
5vukB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5vukA-4xj6A:
undetectable
5vukB-4xj6A:
undetectable		 5vukA-4xj6A:
21.06
5vukB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5vulA-4xj6A:
0.1
5vulB-4xj6A:
undetectable		 5vulA-4xj6A:
21.06
5vulB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5vulA-4xj6A:
0.1
5vulB-4xj6A:
undetectable		 5vulA-4xj6A:
21.06
5vulB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 5vulA-4xj6A:
0.1
5vulB-4xj6A:
undetectable		 5vulA-4xj6A:
21.06
5vulB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 5vulA-4xj6A:
0.1
5vulB-4xj6A:
undetectable		 5vulA-4xj6A:
21.06
5vulB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.06A 5vumA-4xj6A:
1.6
5vumB-4xj6A:
undetectable		 5vumA-4xj6A:
21.06
5vumB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 5vumA-4xj6A:
1.6
5vumB-4xj6A:
undetectable		 5vumA-4xj6A:
21.06
5vumB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.11A 5vumA-4xj6A:
1.6
5vumB-4xj6A:
undetectable		 5vumA-4xj6A:
21.06
5vumB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5vumA-4xj6A:
1.6
5vumB-4xj6A:
undetectable		 5vumA-4xj6A:
21.06
5vumB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 5vunA-4xj6A:
undetectable
5vunB-4xj6A:
undetectable		 5vunA-4xj6A:
21.06
5vunB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5vunA-4xj6A:
undetectable
5vunB-4xj6A:
undetectable		 5vunA-4xj6A:
21.06
5vunB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 5vunA-4xj6A:
undetectable
5vunB-4xj6A:
undetectable		 5vunA-4xj6A:
21.06
5vunB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5vunA-4xj6A:
undetectable
5vunB-4xj6A:
undetectable		 5vunA-4xj6A:
21.06
5vunB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 5vuoA-4xj6A:
undetectable
5vuoB-4xj6A:
undetectable		 5vuoA-4xj6A:
21.06
5vuoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 5vuoA-4xj6A:
undetectable
5vuoB-4xj6A:
undetectable		 5vuoA-4xj6A:
21.06
5vuoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 5vuoA-4xj6A:
undetectable
5vuoB-4xj6A:
undetectable		 5vuoA-4xj6A:
21.06
5vuoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5vuoA-4xj6A:
undetectable
5vuoB-4xj6A:
undetectable		 5vuoA-4xj6A:
21.06
5vuoB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 5vupA-4xj6A:
undetectable
5vupB-4xj6A:
1.6		 5vupA-4xj6A:
21.06
5vupB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5vupA-4xj6A:
undetectable
5vupB-4xj6A:
1.6		 5vupA-4xj6A:
21.06
5vupB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 5vupA-4xj6A:
undetectable
5vupB-4xj6A:
1.6		 5vupA-4xj6A:
21.06
5vupB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5vupA-4xj6A:
undetectable
5vupB-4xj6A:
1.6		 5vupA-4xj6A:
21.06
5vupB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 5vuqA-4xj6A:
undetectable
5vuqB-4xj6A:
undetectable		 5vuqA-4xj6A:
21.06
5vuqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 5vuqA-4xj6A:
undetectable
5vuqB-4xj6A:
undetectable		 5vuqA-4xj6A:
21.06
5vuqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 5vuqA-4xj6A:
undetectable
5vuqB-4xj6A:
undetectable		 5vuqA-4xj6A:
21.06
5vuqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5vuqA-4xj6A:
undetectable
5vuqB-4xj6A:
undetectable		 5vuqA-4xj6A:
21.06
5vuqB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5vurA-4xj6A:
1.6
5vurB-4xj6A:
undetectable		 5vurA-4xj6A:
21.06
5vurB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.14A 5vurA-4xj6A:
1.6
5vurB-4xj6A:
undetectable		 5vurA-4xj6A:
21.06
5vurB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 5vusA-4xj6A:
undetectable
5vusB-4xj6A:
undetectable		 5vusA-4xj6A:
21.06
5vusB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 5vusA-4xj6A:
undetectable
5vusB-4xj6A:
undetectable		 5vusA-4xj6A:
21.06
5vusB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 5vusA-4xj6A:
undetectable
5vusB-4xj6A:
undetectable		 5vusA-4xj6A:
21.06
5vusB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.06A 5vusA-4xj6A:
undetectable
5vusB-4xj6A:
undetectable		 5vusA-4xj6A:
21.06
5vusB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5vutA-4xj6A:
undetectable
5vutB-4xj6A:
undetectable		 5vutA-4xj6A:
21.06
5vutB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 5vutA-4xj6A:
undetectable
5vutB-4xj6A:
undetectable		 5vutA-4xj6A:
21.06
5vutB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 5vutA-4xj6A:
undetectable
5vutB-4xj6A:
undetectable		 5vutA-4xj6A:
21.06
5vutB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5vutA-4xj6A:
undetectable
5vutB-4xj6A:
undetectable		 5vutA-4xj6A:
21.06
5vutB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 5vuuA-4xj6A:
undetectable
5vuuB-4xj6A:
undetectable		 5vuuA-4xj6A:
21.06
5vuuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.13A 5vuuA-4xj6A:
undetectable
5vuuB-4xj6A:
undetectable		 5vuuA-4xj6A:
21.06
5vuuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5vuuA-4xj6A:
undetectable
5vuuB-4xj6A:
undetectable		 5vuuA-4xj6A:
21.06
5vuuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5vuuA-4xj6A:
undetectable
5vuuB-4xj6A:
undetectable		 5vuuA-4xj6A:
21.06
5vuuB-4xj6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 5vuvA-4xj6A:
undetectable
5vuvB-4xj6A:
undetectable		 5vuvA-4xj6A:
20.42
5vuvB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 5vuvA-4xj6A:
undetectable
5vuvB-4xj6A:
undetectable		 5vuvA-4xj6A:
20.42
5vuvB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 5vuvA-4xj6A:
undetectable
5vuvB-4xj6A:
undetectable		 5vuvA-4xj6A:
20.42
5vuvB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5vuvA-4xj6A:
undetectable
5vuvB-4xj6A:
undetectable		 5vuvA-4xj6A:
20.42
5vuvB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.09A 5vuwA-4xj6A:
undetectable
5vuwB-4xj6A:
undetectable		 5vuwA-4xj6A:
20.42
5vuwB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.04A 5vuwA-4xj6A:
undetectable
5vuwB-4xj6A:
undetectable		 5vuwA-4xj6A:
20.42
5vuwB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5vuwA-4xj6A:
undetectable
5vuwB-4xj6A:
undetectable		 5vuwA-4xj6A:
20.42
5vuwB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5vuwA-4xj6A:
undetectable
5vuwB-4xj6A:
undetectable		 5vuwA-4xj6A:
20.42
5vuwB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.08A 5vuxA-4xj6A:
undetectable
5vuxB-4xj6A:
undetectable		 5vuxA-4xj6A:
20.42
5vuxB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 5vuxA-4xj6A:
undetectable
5vuxB-4xj6A:
undetectable		 5vuxA-4xj6A:
20.42
5vuxB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5vuyA-4xj6A:
undetectable
5vuyB-4xj6A:
undetectable		 5vuyA-4xj6A:
20.42
5vuyB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 0.98A 5vuyA-4xj6A:
undetectable
5vuyB-4xj6A:
undetectable		 5vuyA-4xj6A:
20.42
5vuyB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 5vuyA-4xj6A:
undetectable
5vuyB-4xj6A:
undetectable		 5vuyA-4xj6A:
20.42
5vuyB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.04A 5vuyA-4xj6A:
undetectable
5vuyB-4xj6A:
undetectable		 5vuyA-4xj6A:
20.42
5vuyB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 5vuzA-4xj6A:
undetectable
5vuzB-4xj6A:
undetectable		 5vuzA-4xj6A:
20.42
5vuzB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 5vuzA-4xj6A:
undetectable
5vuzB-4xj6A:
undetectable		 5vuzA-4xj6A:
20.42
5vuzB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 5vuzA-4xj6A:
undetectable
5vuzB-4xj6A:
undetectable		 5vuzA-4xj6A:
20.42
5vuzB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5vuzA-4xj6A:
undetectable
5vuzB-4xj6A:
undetectable		 5vuzA-4xj6A:
20.42
5vuzB-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 5vv0A-4xj6A:
2.0
5vv0B-4xj6A:
2.1		 5vv0A-4xj6A:
20.42
5vv0B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 5vv0A-4xj6A:
2.0
5vv0B-4xj6A:
2.1		 5vv0A-4xj6A:
20.42
5vv0B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 5vv0A-4xj6A:
2.0
5vv0B-4xj6A:
2.1		 5vv0A-4xj6A:
20.42
5vv0B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5vv0A-4xj6A:
2.0
5vv0B-4xj6A:
2.1		 5vv0A-4xj6A:
20.42
5vv0B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 5vv1A-4xj6A:
undetectable
5vv1B-4xj6A:
2.2		 5vv1A-4xj6A:
20.42
5vv1B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 5vv1A-4xj6A:
undetectable
5vv1B-4xj6A:
2.2		 5vv1A-4xj6A:
20.42
5vv1B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 5vv1A-4xj6A:
undetectable
5vv1B-4xj6A:
2.2		 5vv1A-4xj6A:
20.42
5vv1B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 5vv1A-4xj6A:
undetectable
5vv1B-4xj6A:
2.2		 5vv1A-4xj6A:
20.42
5vv1B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 5vv2A-4xj6A:
undetectable
5vv2B-4xj6A:
undetectable		 5vv2A-4xj6A:
20.42
5vv2B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 5vv2A-4xj6A:
undetectable
5vv2B-4xj6A:
undetectable		 5vv2A-4xj6A:
20.42
5vv2B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 5vv2A-4xj6A:
undetectable
5vv2B-4xj6A:
undetectable		 5vv2A-4xj6A:
20.42
5vv2B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5vv2A-4xj6A:
undetectable
5vv2B-4xj6A:
undetectable		 5vv2A-4xj6A:
20.42
5vv2B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.16A 5vv3A-4xj6A:
undetectable
5vv3B-4xj6A:
undetectable		 5vv3A-4xj6A:
20.42
5vv3B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.06A 5vv3A-4xj6A:
undetectable
5vv3B-4xj6A:
undetectable		 5vv3A-4xj6A:
20.42
5vv3B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.21A 5vv3A-4xj6A:
undetectable
5vv3B-4xj6A:
undetectable		 5vv3A-4xj6A:
20.42
5vv3B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5vv3A-4xj6A:
undetectable
5vv3B-4xj6A:
undetectable		 5vv3A-4xj6A:
20.42
5vv3B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 5vv4A-4xj6A:
undetectable
5vv4B-4xj6A:
undetectable		 5vv4A-4xj6A:
20.42
5vv4B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 5vv4A-4xj6A:
undetectable
5vv4B-4xj6A:
undetectable		 5vv4A-4xj6A:
20.42
5vv4B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 5vv5A-4xj6A:
undetectable
5vv5B-4xj6A:
undetectable		 5vv5A-4xj6A:
20.42
5vv5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 5vv5A-4xj6A:
undetectable
5vv5B-4xj6A:
undetectable		 5vv5A-4xj6A:
20.42
5vv5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.24A 5vv5A-4xj6A:
undetectable
5vv5B-4xj6A:
undetectable		 5vv5A-4xj6A:
20.42
5vv5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 5vv5A-4xj6A:
undetectable
5vv5B-4xj6A:
undetectable		 5vv5A-4xj6A:
20.42
5vv5B-4xj6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 5 PHE A 349
THR A 302
ASP A 344
ASN A 176
 None
None
GH3  A 503 (-2.9A)
GH3  A 504 ( 4.8A)
 1.45A 5ybbA-4xj6A:
undetectable		 5ybbA-4xj6A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.07A 6auqA-4xj6A:
1.7
6auqB-4xj6A:
undetectable		 6auqA-4xj6A:
10.81
6auqB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 6auqA-4xj6A:
1.7
6auqB-4xj6A:
undetectable		 6auqA-4xj6A:
10.81
6auqB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 6auqA-4xj6A:
1.7
6auqB-4xj6A:
undetectable		 6auqA-4xj6A:
10.81
6auqB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 6auqA-4xj6A:
1.7
6auqB-4xj6A:
undetectable		 6auqA-4xj6A:
10.81
6auqB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 6aurA-4xj6A:
undetectable
6aurB-4xj6A:
undetectable		 6aurA-4xj6A:
10.81
6aurB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 6aurA-4xj6A:
undetectable
6aurB-4xj6A:
undetectable		 6aurA-4xj6A:
10.81
6aurB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 6aurA-4xj6A:
undetectable
6aurB-4xj6A:
undetectable		 6aurA-4xj6A:
10.81
6aurB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 6aurA-4xj6A:
undetectable
6aurB-4xj6A:
undetectable		 6aurA-4xj6A:
10.81
6aurB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.11A 6ausA-4xj6A:
undetectable
6ausB-4xj6A:
undetectable		 6ausA-4xj6A:
10.81
6ausB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.10A 6ausA-4xj6A:
undetectable
6ausB-4xj6A:
undetectable		 6ausA-4xj6A:
10.81
6ausB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 6ausA-4xj6A:
undetectable
6ausB-4xj6A:
undetectable		 6ausA-4xj6A:
10.81
6ausB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 6ausA-4xj6A:
undetectable
6ausB-4xj6A:
undetectable		 6ausA-4xj6A:
10.81
6ausB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 6autA-4xj6A:
undetectable
6autB-4xj6A:
undetectable		 6autA-4xj6A:
10.81
6autB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 6autA-4xj6A:
undetectable
6autB-4xj6A:
undetectable		 6autA-4xj6A:
10.81
6autB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 6autA-4xj6A:
undetectable
6autB-4xj6A:
undetectable		 6autA-4xj6A:
10.81
6autB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 6autA-4xj6A:
undetectable
6autB-4xj6A:
undetectable		 6autA-4xj6A:
10.81
6autB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 6auuA-4xj6A:
2.1
6auuB-4xj6A:
undetectable		 6auuA-4xj6A:
10.81
6auuB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 6auuA-4xj6A:
2.1
6auuB-4xj6A:
undetectable		 6auuA-4xj6A:
10.81
6auuB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.20A 6auuA-4xj6A:
undetectable
6auuB-4xj6A:
undetectable		 6auuA-4xj6A:
10.81
6auuB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 6auuA-4xj6A:
undetectable
6auuB-4xj6A:
undetectable		 6auuA-4xj6A:
10.81
6auuB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 6auvA-4xj6A:
undetectable
6auvB-4xj6A:
undetectable		 6auvA-4xj6A:
10.81
6auvB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.08A 6auvA-4xj6A:
undetectable
6auvB-4xj6A:
undetectable		 6auvA-4xj6A:
10.81
6auvB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 6auvA-4xj6A:
undetectable
6auvB-4xj6A:
undetectable		 6auvA-4xj6A:
10.81
6auvB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 6auvA-4xj6A:
undetectable
6auvB-4xj6A:
undetectable		 6auvA-4xj6A:
10.81
6auvB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 6auwA-4xj6A:
1.6
6auwB-4xj6A:
undetectable		 6auwA-4xj6A:
10.81
6auwB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 6auwA-4xj6A:
1.6
6auwB-4xj6A:
undetectable		 6auwA-4xj6A:
10.81
6auwB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.16A 6auwA-4xj6A:
1.7
6auwB-4xj6A:
undetectable		 6auwA-4xj6A:
10.81
6auwB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 6auwA-4xj6A:
1.7
6auwB-4xj6A:
undetectable		 6auwA-4xj6A:
10.81
6auwB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.13A 6auxA-4xj6A:
undetectable
6auxB-4xj6A:
undetectable		 6auxA-4xj6A:
10.81
6auxB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.13A 6auxA-4xj6A:
undetectable
6auxB-4xj6A:
undetectable		 6auxA-4xj6A:
10.81
6auxB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 6auxA-4xj6A:
undetectable
6auxB-4xj6A:
undetectable		 6auxA-4xj6A:
10.81
6auxB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 6auxA-4xj6A:
undetectable
6auxB-4xj6A:
undetectable		 6auxA-4xj6A:
10.81
6auxB-4xj6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 6auyA-4xj6A:
undetectable
6auyB-4xj6A:
2.0		 6auyA-4xj6A:
12.20
6auyB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.07A 6auyA-4xj6A:
undetectable
6auyB-4xj6A:
2.0		 6auyA-4xj6A:
12.20
6auyB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.17A 6auyA-4xj6A:
undetectable
6auyB-4xj6A:
2.0		 6auyA-4xj6A:
12.20
6auyB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 6auyA-4xj6A:
undetectable
6auyB-4xj6A:
2.0		 6auyA-4xj6A:
12.20
6auyB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 6auzA-4xj6A:
undetectable
6auzB-4xj6A:
3.0		 6auzA-4xj6A:
12.20
6auzB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 6auzA-4xj6A:
undetectable
6auzB-4xj6A:
3.0		 6auzA-4xj6A:
12.20
6auzB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 6auzA-4xj6A:
undetectable
6auzB-4xj6A:
3.0		 6auzA-4xj6A:
12.20
6auzB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 6auzA-4xj6A:
undetectable
6auzB-4xj6A:
3.0		 6auzA-4xj6A:
12.20
6auzB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.14A 6av0A-4xj6A:
undetectable
6av0B-4xj6A:
undetectable		 6av0A-4xj6A:
12.20
6av0B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.09A 6av0A-4xj6A:
undetectable
6av0B-4xj6A:
undetectable		 6av0A-4xj6A:
12.20
6av0B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.12A 6av0A-4xj6A:
undetectable
6av0B-4xj6A:
undetectable		 6av0A-4xj6A:
12.20
6av0B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.09A 6av0A-4xj6A:
undetectable
6av0B-4xj6A:
undetectable		 6av0A-4xj6A:
12.20
6av0B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 6av1A-4xj6A:
undetectable
6av1B-4xj6A:
undetectable		 6av1A-4xj6A:
12.20
6av1B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.04A 6av1A-4xj6A:
undetectable
6av1B-4xj6A:
undetectable		 6av1A-4xj6A:
12.20
6av1B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 6av1A-4xj6A:
undetectable
6av1B-4xj6A:
undetectable		 6av1A-4xj6A:
12.20
6av1B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.15A 6av1A-4xj6A:
undetectable
6av1B-4xj6A:
undetectable		 6av1A-4xj6A:
12.20
6av1B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.18A 6av2A-4xj6A:
undetectable
6av2B-4xj6A:
undetectable		 6av2A-4xj6A:
12.20
6av2B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 6av2A-4xj6A:
undetectable
6av2B-4xj6A:
undetectable		 6av2A-4xj6A:
12.20
6av2B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.18A 6av2A-4xj6A:
undetectable
6av2B-4xj6A:
undetectable		 6av2A-4xj6A:
12.20
6av2B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 6av2A-4xj6A:
undetectable
6av2B-4xj6A:
undetectable		 6av2A-4xj6A:
12.20
6av2B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.10A 6av3A-4xj6A:
undetectable
6av3B-4xj6A:
2.0		 6av3A-4xj6A:
12.20
6av3B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.05A 6av3A-4xj6A:
undetectable
6av3B-4xj6A:
2.0		 6av3A-4xj6A:
12.20
6av3B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 6av3A-4xj6A:
undetectable
6av3B-4xj6A:
2.0		 6av3A-4xj6A:
12.20
6av3B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 6av3A-4xj6A:
undetectable
6av3B-4xj6A:
2.0		 6av3A-4xj6A:
12.20
6av3B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 6av4A-4xj6A:
undetectable
6av4B-4xj6A:
undetectable		 6av4A-4xj6A:
12.20
6av4B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.05A 6av4A-4xj6A:
undetectable
6av4B-4xj6A:
undetectable		 6av4A-4xj6A:
12.20
6av4B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 6av4A-4xj6A:
undetectable
6av4B-4xj6A:
undetectable		 6av4A-4xj6A:
12.20
6av4B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.08A 6av4A-4xj6A:
undetectable
6av4B-4xj6A:
undetectable		 6av4A-4xj6A:
12.20
6av4B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.16A 6av5A-4xj6A:
undetectable
6av5B-4xj6A:
undetectable		 6av5A-4xj6A:
12.20
6av5B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.12A 6av5A-4xj6A:
undetectable
6av5B-4xj6A:
undetectable		 6av5A-4xj6A:
12.20
6av5B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.13A 6av5A-4xj6A:
undetectable
6av5B-4xj6A:
undetectable		 6av5A-4xj6A:
12.20
6av5B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.12A 6av5A-4xj6A:
undetectable
6av5B-4xj6A:
undetectable		 6av5A-4xj6A:
12.20
6av5B-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.15A 6cicA-4xj6A:
undetectable
6cicB-4xj6A:
undetectable		 6cicA-4xj6A:
12.20
6cicB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.13A 6cicA-4xj6A:
undetectable
6cicB-4xj6A:
undetectable		 6cicA-4xj6A:
12.20
6cicB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.14A 6cicA-4xj6A:
undetectable
6cicB-4xj6A:
undetectable		 6cicA-4xj6A:
12.20
6cicB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.10A 6cicA-4xj6A:
undetectable
6cicB-4xj6A:
undetectable		 6cicA-4xj6A:
12.20
6cicB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 276
VAL A 305
PHE A 264
GLU A 266
 None
 1.12A 6cidA-4xj6A:
undetectable
6cidB-4xj6A:
undetectable		 6cidA-4xj6A:
12.20
6cidB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 305
TRP A 263
PHE A 264
GLU A 266
 None
 1.11A 6cidA-4xj6A:
undetectable
6cidB-4xj6A:
undetectable		 6cidA-4xj6A:
12.20
6cidB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 264
GLU A 266
ARG A 276
VAL A 305
 None
 1.15A 6cidA-4xj6A:
undetectable
6cidB-4xj6A:
undetectable		 6cidA-4xj6A:
12.20
6cidB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 7 TRP A 263
PHE A 264
GLU A 266
VAL A 305
 None
 1.11A 6cidA-4xj6A:
undetectable
6cidB-4xj6A:
undetectable		 6cidA-4xj6A:
12.20
6cidB-4xj6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		4 / 5 SER A 146
VAL A 140
ASN A 242
PRO A 137
 None
 1.41A 6fi4A-4xj6A:
undetectable
6fi4B-4xj6A:
undetectable		 6fi4A-4xj6A:
21.45
6fi4B-4xj6A:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 4xj6 VC0179-LIKE PROTEIN
(Escherichia
coli) 		5 / 10 ALA A 303
THR A 365
PHE A 333
PHE A 349
VAL A 337
 None
 1.47A 6hu9C-4xj6A:
undetectable		 6hu9C-4xj6A:
21.46