SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xjc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 4xjc DEOXYCYTIDINE
TRIPHOSPHATE
DEAMINASE
(Bacillus
halodurans) 		4 / 9 ILE A 122
ALA A 111
VAL A  95
GLU A  96
 TTP  A 201 (-4.1A)
None
TTP  A 201 ( 4.6A)
None
 0.73A 2vufA-4xjcA:
undetectable		 2vufA-4xjcA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 4xjc DEOXYCYTIDINE
TRIPHOSPHATE
DEAMINASE
(Bacillus
halodurans) 		4 / 4 LEU A  17
ALA A  93
VAL A 114
PRO A 116
 None
None
TTP  A 201 ( 4.0A)
None
 0.94A 3gv1B-4xjcA:
undetectable		 3gv1B-4xjcA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)		 4xjc DEOXYCYTIDINE
TRIPHOSPHATE
DEAMINASE
(Bacillus
halodurans) 		5 / 10 ILE A  69
ALA A  79
ILE A 108
LEU A  77
LEU A 106
 None
 0.96A 4rz7A-4xjcA:
undetectable		 4rz7A-4xjcA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 4xjc DEOXYCYTIDINE
TRIPHOSPHATE
DEAMINASE
(Bacillus
halodurans) 		5 / 12 GLY A  97
VAL A 101
ILE A 108
THR A  80
GLY A  37
 None
 0.81A 5koxA-4xjcA:
undetectable		 5koxA-4xjcA:
15.93