SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		4 / 5 LEU A 137
GLU A 135
ALA A 144
LEU A 141
 None
 1.09A 1eta1-4xjnA:
undetectable		 1eta1-4xjnA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		4 / 5 LEU A 137
GLU A 135
ALA A 144
LEU A 141
 None
 1.05A 1eta2-4xjnA:
undetectable		 1eta2-4xjnA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		4 / 8 ILE A  99
LEU A  74
LYS A 225
GLY A 226
 None
 1.01A 1os6A-4xjnA:
undetectable		 1os6A-4xjnA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_A_C2FA1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		5 / 11 TYR A 329
THR A 294
LEU A 277
SER A 290
LEU A 273
 None
 1.38A 2idkA-4xjnA:
undetectable
2idkB-4xjnA:
undetectable
2idkC-4xjnA:
undetectable
2idkD-4xjnA:
undetectable		 2idkA-4xjnA:
20.49
2idkB-4xjnA:
20.49
2idkC-4xjnA:
20.49
2idkD-4xjnA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_B_C2FB1420_0
(GLYCINE
N-METHYLTRANSFERASE)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		5 / 10 LEU A 273
SER A 290
LEU A 277
TYR A 329
THR A 294
 None
 1.37A 2idkA-4xjnA:
0.0
2idkB-4xjnA:
0.0
2idkC-4xjnA:
0.0
2idkD-4xjnA:
0.0		 2idkA-4xjnA:
20.49
2idkB-4xjnA:
20.49
2idkC-4xjnA:
20.49
2idkD-4xjnA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		5 / 10 ALA A 174
LEU A  56
VAL A  59
LEU A 137
ILE A 218
 None
 1.07A 3jw3A-4xjnA:
undetectable		 3jw3A-4xjnA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		4 / 5 GLY A 258
LYS A 259
GLU A 262
GLY A 255
 None
 0.97A 3onnA-4xjnA:
undetectable		 3onnA-4xjnA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		4 / 8 ILE A  99
LEU A  74
LYS A 225
GLY A 226
 None
 0.97A 3selX-4xjnA:
undetectable		 3selX-4xjnA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_D_C2FD1200_0
(GLYCINE
N-METHYLTRANSFERASE)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		5 / 12 LEU A 273
SER A 290
LEU A 277
TYR A 329
THR A 294
 None
 1.39A 3thrA-4xjnA:
undetectable
3thrB-4xjnA:
undetectable
3thrC-4xjnA:
undetectable
3thrD-4xjnA:
undetectable		 3thrA-4xjnA:
20.49
3thrB-4xjnA:
20.49
3thrC-4xjnA:
20.49
3thrD-4xjnA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_2
(SUGAR KINASE PROTEIN)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		4 / 4 SER A 169
SER A  49
TYR A 209
PRO A  80
 None
 1.31A 4e3aB-4xjnA:
0.0		 4e3aB-4xjnA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		4 / 5 MET A  76
LEU A  73
PRO A  80
SER A  81
 None
 1.40A 4kmmB-4xjnA:
2.6		 4kmmB-4xjnA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		5 / 12 LEU A  73
THR A 178
ALA A 174
VAL A 170
ILE A 219
 None
 1.01A 4x1yB-4xjnA:
undetectable		 4x1yB-4xjnA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		5 / 12 LEU A  73
THR A 178
ALA A 174
VAL A 170
ILE A 219
 None
 1.00A 4x1yD-4xjnA:
undetectable		 4x1yD-4xjnA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		5 / 12 LEU A  73
THR A 178
ALA A 174
VAL A 170
ILE A 219
 None
 0.99A 4x20B-4xjnA:
undetectable		 4x20B-4xjnA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		5 / 11 LEU A  73
THR A 178
ALA A 174
VAL A 170
ILE A 219
 None
 0.98A 4x20D-4xjnA:
undetectable		 4x20D-4xjnA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		5 / 12 ASP A 149
LEU A 137
ALA A 144
ARG A  50
GLY A 154
 None
 1.06A 6b0iB-4xjnA:
undetectable		 6b0iB-4xjnA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		4 / 8 LEU A 315
TYR A 312
GLU A 262
THR A 178
 None
 1.13A 6c71B-4xjnA:
undetectable		 6c71B-4xjnA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 4xjn NUCLEOCAPSID
(Mammalian
rubulavirus
5) 		4 / 5 ILE A  58
SER A  61
ALA A 129
LEU A 114
 None
 1.06A 6dwnA-4xjnA:
undetectable		 6dwnA-4xjnA:
8.43