SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xkq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 0.98A 1v54N-4xkqA:
0.5
1v54W-4xkqA:
undetectable		 1v54N-4xkqA:
20.93
1v54W-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 8 SER A 437
TYR A 438
TYR A 387
HIS A 242
 None
 1.33A 2bteA-4xkqA:
undetectable		 2bteA-4xkqA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 1.01A 2dyrN-4xkqA:
0.5
2dyrW-4xkqA:
undetectable		 2dyrN-4xkqA:
20.93
2dyrW-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 6 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 0.95A 2einN-4xkqA:
undetectable
2einW-4xkqA:
undetectable		 2einN-4xkqA:
20.93
2einW-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 5 ILE A 346
MET A 247
LEU A 238
LEU A 255
 None
 0.76A 2zb7A-4xkqA:
undetectable		 2zb7A-4xkqA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 1.00A 3ablA-4xkqA:
0.5
3ablJ-4xkqA:
undetectable		 3ablA-4xkqA:
20.93
3ablJ-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 6 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 0.99A 3ag1N-4xkqA:
undetectable
3ag1W-4xkqA:
undetectable		 3ag1N-4xkqA:
20.93
3ag1W-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6M_A_SPMA501_1
(SPERMINE SYNTHASE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		5 / 11 TYR A 138
VAL A 146
TYR A 161
GLN A 163
GLU A  26
 None
 1.38A 3c6mA-4xkqA:
undetectable		 3c6mA-4xkqA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 4 PRO A 180
TYR A 156
GLY A 154
THR A 153
 None
 0.89A 3ib0A-4xkqA:
2.2		 3ib0A-4xkqA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A  52
VAL A  29
GLY A 154
LEU A 169
ILE A 158
 None
 0.86A 3ku1A-4xkqA:
undetectable		 3ku1A-4xkqA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A  52
VAL A  29
GLY A 154
LEU A 169
ILE A 158
 None
 0.87A 3ku1C-4xkqA:
undetectable		 3ku1C-4xkqA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_B_GLYB509_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 4 PHE A 371
THR A 373
LEU A 237
TYR A 438
 None
 1.38A 3pgyB-4xkqA:
undetectable		 3pgyB-4xkqA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ILE A  48
ILE A 407
ILE A 426
ARG A 419
ASP A 378
 None
 1.29A 3phaB-4xkqA:
undetectable		 3phaB-4xkqA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 6 GLN A 444
ILE A 445
SER A 370
SER A 236
 GOL  A 507 ( 3.9A)
None
HIS  A 502 ( 4.1A)
None
 1.13A 3pmzD-4xkqA:
undetectable		 3pmzD-4xkqA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ILE A 185
VAL A 187
TYR A 189
THR A  19
ILE A 465
 None
 1.16A 3vrjA-4xkqA:
undetectable
3vrjC-4xkqA:
undetectable		 3vrjA-4xkqA:
20.00
3vrjC-4xkqA:
2.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 6 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 1.05A 3wg7N-4xkqA:
0.5
3wg7W-4xkqA:
undetectable		 3wg7N-4xkqA:
20.93
3wg7W-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		3 / 3 PRO A 180
TYR A 156
GLY A 154
 None
 0.72A 4g2zA-4xkqA:
5.0		 4g2zA-4xkqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		3 / 3 ARG A 165
LYS A 166
LYS A 162
 None
 1.08A 4k50A-4xkqA:
undetectable		 4k50A-4xkqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		3 / 3 ARG A 165
LYS A 166
LYS A 162
 None
 1.16A 4k50E-4xkqA:
undetectable		 4k50E-4xkqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		3 / 3 ARG A 165
LYS A 166
LYS A 162
 None
 1.12A 4k50I-4xkqA:
undetectable		 4k50I-4xkqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A 134
ARG A 376
SER A  96
ALA A 392
 HIS  A 503 ( 4.8A)
None
None
None
 1.05A 4lv9A-4xkqA:
undetectable
4lv9B-4xkqA:
undetectable		 4lv9A-4xkqA:
21.06
4lv9B-4xkqA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 8 ASN A 436
PRO A 435
MET A 239
TYR A 441
 None
 1.10A 4v2zB-4xkqA:
undetectable		 4v2zB-4xkqA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 8 ASN A 436
PRO A 435
MET A 239
TYR A 441
 None
 1.13A 4v30B-4xkqA:
undetectable		 4v30B-4xkqA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A  15
LEU A 464
SER A 228
ARG A 196
ILE A  13
 None
GOL  A 507 ( 4.3A)
GOL  A 513 ( 4.9A)
None
None
 1.14A 4x1fA-4xkqA:
undetectable		 4x1fA-4xkqA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A  15
LEU A 464
SER A 228
ARG A 196
ILE A  13
 None
GOL  A 507 ( 4.3A)
GOL  A 513 ( 4.9A)
None
None
 1.11A 4x1gA-4xkqA:
undetectable		 4x1gA-4xkqA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ASN A 244
LYS A 245
LYS A 246
LEU A 304
 None
 1.25A 4yv5B-4xkqA:
undetectable		 4yv5B-4xkqA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 8 ASN A 436
PRO A 435
SER A 278
TYR A 441
 None
 1.33A 5amiB-4xkqA:
undetectable		 5amiB-4xkqA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 0.98A 5b1bA-4xkqA:
undetectable
5b1bJ-4xkqA:
undetectable		 5b1bA-4xkqA:
20.93
5b1bJ-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 0.99A 5iy5A-4xkqA:
0.4
5iy5J-4xkqA:
undetectable		 5iy5A-4xkqA:
20.93
5iy5J-4xkqA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 8 TYR A 387
THR A 373
PRO A 290
ILE A 287
 None
None
GOL  A 506 (-4.2A)
None
 1.07A 5jhdE-4xkqA:
undetectable
5jhdG-4xkqA:
undetectable		 5jhdE-4xkqA:
19.62
5jhdG-4xkqA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMW_A_PNNA305_0
(BETA-LACTAMASE
TOHO-1)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 4 ASN A 194
PRO A 212
ASN A 214
ASP A 218
 None
 1.40A 5kmwA-4xkqA:
0.0		 5kmwA-4xkqA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		3 / 3 LYS A 204
ASN A 199
SER A  14
 None
 1.22A 5yw0A-4xkqA:
undetectable		 5yw0A-4xkqA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 6 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 1.01A 5z86N-4xkqA:
0.5
5z86W-4xkqA:
undetectable		 5z86N-4xkqA:
20.93
5z86W-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 8 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 0.97A 5zcoA-4xkqA:
0.5
5zcoJ-4xkqA:
undetectable		 5zcoA-4xkqA:
20.93
5zcoJ-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 6 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 1.02A 5zcoN-4xkqA:
0.5
5zcoW-4xkqA:
undetectable		 5zcoN-4xkqA:
20.93
5zcoW-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		3 / 3 ARG A 196
ILE A 208
SER A  14
 None
 0.72A 5zw2A-4xkqA:
undetectable		 5zw2A-4xkqA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A 259
MET A 368
THR A 367
LEU A 319
 None
 0.95A 6nmfA-4xkqA:
0.6
6nmfJ-4xkqA:
undetectable		 6nmfA-4xkqA:
20.93
6nmfJ-4xkqA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A 406
ILE A 422
ASP A 378
GLY A 380
ASN A 384
 None
 1.34A 6qxsD-4xkqA:
undetectable		 6qxsD-4xkqA:
19.79