SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xlt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 7 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.03A 1v55C-4xltA:
undetectable
1v55N-4xltA:
undetectable
1v55P-4xltA:
undetectable
1v55C-4xltA:
18.29
1v55N-4xltA:
12.73
1v55P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.06A 2y69C-4xltA:
undetectable
2y69N-4xltA:
undetectable
2y69P-4xltA:
undetectable
2y69C-4xltA:
18.29
2y69N-4xltA:
12.73
2y69P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.04A 3ablA-4xltA:
undetectable
3ablC-4xltA:
undetectable
3ablP-4xltA:
undetectable
3ablA-4xltA:
12.73
3ablC-4xltA:
18.29
3ablP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.04A 3ablC-4xltA:
undetectable
3ablN-4xltA:
undetectable
3ablP-4xltA:
undetectable
3ablC-4xltA:
18.29
3ablN-4xltA:
12.73
3ablP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.07A 3abmA-4xltA:
undetectable
3abmC-4xltA:
undetectable
3abmP-4xltA:
undetectable
3abmA-4xltA:
12.73
3abmC-4xltA:
18.29
3abmP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.03A 3asnC-4xltA:
undetectable
3asnN-4xltA:
undetectable
3asnP-4xltA:
undetectable
3asnC-4xltA:
18.29
3asnN-4xltA:
12.73
3asnP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.08A 3asoA-4xltA:
undetectable
3asoC-4xltA:
undetectable
3asoP-4xltA:
undetectable
3asoA-4xltA:
12.73
3asoC-4xltA:
18.29
3asoP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.04A 3asoC-4xltA:
undetectable
3asoN-4xltA:
undetectable
3asoP-4xltA:
undetectable
3asoC-4xltA:
18.29
3asoN-4xltA:
12.73
3asoP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 GLY A  46
VAL A  79
LEU A  75
PRO A  76
None
1.13A 3bgdB-4xltA:
2.4
3bgdB-4xltA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.05A 3wg7A-4xltA:
undetectable
3wg7C-4xltA:
undetectable
3wg7P-4xltA:
undetectable
3wg7A-4xltA:
12.73
3wg7C-4xltA:
18.29
3wg7P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.00A 3wg7C-4xltA:
undetectable
3wg7N-4xltA:
undetectable
3wg7P-4xltA:
undetectable
3wg7C-4xltA:
18.29
3wg7N-4xltA:
12.73
3wg7P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.08A 3x2qA-4xltA:
undetectable
3x2qC-4xltA:
undetectable
3x2qP-4xltA:
undetectable
3x2qA-4xltA:
12.73
3x2qC-4xltA:
18.29
3x2qP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.05A 3x2qC-4xltA:
undetectable
3x2qN-4xltA:
undetectable
3x2qP-4xltA:
undetectable
3x2qC-4xltA:
18.29
3x2qN-4xltA:
12.73
3x2qP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
3 / 3 PRO A  76
LEU A  75
HIS A  41
None
0.70A 4pevA-4xltA:
6.6
4pevA-4xltA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 6 ASP A   2
ALA A   0
THR A  26
THR A  27
None
1.30A 4z4cA-4xltA:
4.9
4z4cA-4xltA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 5 ASP A   2
ALA A   0
THR A  26
THR A  27
None
1.33A 4z4gA-4xltA:
3.1
4z4gA-4xltA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 6 ASP A   2
ALA A   0
THR A  26
THR A  27
None
1.34A 4z4iA-4xltA:
3.6
4z4iA-4xltA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.08A 5b1aA-4xltA:
undetectable
5b1aC-4xltA:
undetectable
5b1aP-4xltA:
undetectable
5b1aA-4xltA:
12.73
5b1aC-4xltA:
18.29
5b1aP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.11A 5b1bA-4xltA:
undetectable
5b1bC-4xltA:
undetectable
5b1bP-4xltA:
undetectable
5b1bA-4xltA:
12.73
5b1bC-4xltA:
18.29
5b1bP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.07A 5b3sA-4xltA:
undetectable
5b3sC-4xltA:
undetectable
5b3sP-4xltA:
undetectable
5b3sA-4xltA:
12.73
5b3sC-4xltA:
18.29
5b3sP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
0.99A 5iy5C-4xltA:
undetectable
5iy5N-4xltA:
undetectable
5iy5P-4xltA:
undetectable
5iy5C-4xltA:
18.43
5iy5N-4xltA:
12.73
5iy5P-4xltA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
0.92A 5w97A-4xltA:
undetectable
5w97C-4xltA:
undetectable
5w97c-4xltA:
undetectable
5w97A-4xltA:
12.73
5w97C-4xltA:
18.29
5w97c-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 7 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
0.94A 5w97C-4xltA:
undetectable
5w97a-4xltA:
undetectable
5w97c-4xltA:
undetectable
5w97C-4xltA:
18.29
5w97a-4xltA:
12.73
5w97c-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.06A 5wauA-4xltA:
undetectable
5wauC-4xltA:
undetectable
5wauc-4xltA:
undetectable
5wauA-4xltA:
12.73
5wauC-4xltA:
18.29
5wauc-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 7 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.01A 5wauC-4xltA:
undetectable
5waua-4xltA:
undetectable
5wauc-4xltA:
undetectable
5wauC-4xltA:
18.29
5waua-4xltA:
12.73
5wauc-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
0.97A 5x19A-4xltA:
undetectable
5x19C-4xltA:
undetectable
5x19P-4xltA:
undetectable
5x19A-4xltA:
12.73
5x19C-4xltA:
18.29
5x19P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 7 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
0.96A 5x1bA-4xltA:
undetectable
5x1bC-4xltA:
undetectable
5x1bP-4xltA:
undetectable
5x1bA-4xltA:
12.73
5x1bC-4xltA:
18.29
5x1bP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 7 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
0.93A 5x1fA-4xltA:
undetectable
5x1fC-4xltA:
undetectable
5x1fP-4xltA:
undetectable
5x1fA-4xltA:
12.73
5x1fC-4xltA:
18.29
5x1fP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.02A 5xdqA-4xltA:
undetectable
5xdqC-4xltA:
undetectable
5xdqP-4xltA:
undetectable
5xdqA-4xltA:
12.73
5xdqC-4xltA:
18.29
5xdqP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.01A 5xdqC-4xltA:
undetectable
5xdqN-4xltA:
undetectable
5xdqP-4xltA:
undetectable
5xdqC-4xltA:
18.29
5xdqN-4xltA:
12.73
5xdqP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.03A 5xdxC-4xltA:
undetectable
5xdxN-4xltA:
undetectable
5xdxP-4xltA:
undetectable
5xdxC-4xltA:
18.36
5xdxN-4xltA:
12.73
5xdxP-4xltA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.06A 5z84A-4xltA:
undetectable
5z84C-4xltA:
undetectable
5z84P-4xltA:
undetectable
5z84A-4xltA:
12.73
5z84C-4xltA:
18.29
5z84P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 7 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.04A 5z84C-4xltA:
undetectable
5z84N-4xltA:
undetectable
5z84P-4xltA:
undetectable
5z84C-4xltA:
18.29
5z84N-4xltA:
12.73
5z84P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.08A 5z85A-4xltA:
undetectable
5z85C-4xltA:
undetectable
5z85P-4xltA:
undetectable
5z85A-4xltA:
12.73
5z85C-4xltA:
18.29
5z85P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 7 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.04A 5z85C-4xltA:
undetectable
5z85N-4xltA:
undetectable
5z85P-4xltA:
undetectable
5z85C-4xltA:
18.29
5z85N-4xltA:
12.73
5z85P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.05A 5z86A-4xltA:
undetectable
5z86C-4xltA:
undetectable
5z86P-4xltA:
undetectable
5z86A-4xltA:
12.73
5z86C-4xltA:
18.29
5z86P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.04A 5z86C-4xltA:
undetectable
5z86N-4xltA:
undetectable
5z86P-4xltA:
undetectable
5z86C-4xltA:
18.29
5z86N-4xltA:
12.73
5z86P-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.05A 5zcoA-4xltA:
undetectable
5zcoC-4xltA:
undetectable
5zcoP-4xltA:
undetectable
5zcoA-4xltA:
12.73
5zcoC-4xltA:
18.29
5zcoP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.03A 5zcoC-4xltA:
undetectable
5zcoN-4xltA:
undetectable
5zcoP-4xltA:
undetectable
5zcoC-4xltA:
18.29
5zcoN-4xltA:
12.73
5zcoP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.07A 5zcpA-4xltA:
undetectable
5zcpC-4xltA:
undetectable
5zcpP-4xltA:
undetectable
5zcpA-4xltA:
12.73
5zcpC-4xltA:
18.29
5zcpP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
1.04A 5zcpC-4xltA:
undetectable
5zcpN-4xltA:
undetectable
5zcpP-4xltA:
undetectable
5zcpC-4xltA:
18.29
5zcpN-4xltA:
12.73
5zcpP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
1.07A 5zcqA-4xltA:
undetectable
5zcqC-4xltA:
undetectable
5zcqP-4xltA:
undetectable
5zcqA-4xltA:
12.73
5zcqC-4xltA:
18.29
5zcqP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 8 LEU A 123
HIS A  41
ASP A  51
THR A  52
None
0.96A 6nknC-4xltA:
undetectable
6nknN-4xltA:
undetectable
6nknP-4xltA:
undetectable
6nknC-4xltA:
18.29
6nknN-4xltA:
12.73
6nknP-4xltA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4xlt RESPONSE REGULATOR
RECEIVER PROTEIN

(Dyadobacter
fermentans)
4 / 7 HIS A  41
ASP A  51
THR A  52
LEU A 123
None
0.97A 6nmfA-4xltA:
undetectable
6nmfC-4xltA:
undetectable
6nmfP-4xltA:
undetectable
6nmfA-4xltA:
12.73
6nmfC-4xltA:
18.29
6nmfP-4xltA:
18.29