SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4xng UNCHARACTERIZED
PROTEIN MG218.1
(Mycoplasma
genitalium) 		5 / 9 LEU A 138
ILE A 134
LEU A 181
ARG A 182
ILE A 178
 None
 1.02A 2f78A-4xngA:
undetectable		 2f78A-4xngA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4xng UNCHARACTERIZED
PROTEIN MG218.1
(Mycoplasma
genitalium) 		5 / 9 LEU A 138
ILE A 134
LEU A 181
ARG A 182
ILE A 178
 None
 0.96A 2f78B-4xngA:
undetectable		 2f78B-4xngA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4xng UNCHARACTERIZED
PROTEIN MG218.1
(Mycoplasma
genitalium) 		5 / 9 LEU A 138
ILE A 134
LEU A 181
ARG A 182
ILE A 178
 None
 1.10A 2f7aA-4xngA:
undetectable		 2f7aA-4xngA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4xng UNCHARACTERIZED
PROTEIN MG218.1
(Mycoplasma
genitalium) 		5 / 10 LEU A 138
ILE A 134
LEU A 181
ARG A 182
ILE A 178
 None
 0.98A 2f8dA-4xngA:
undetectable		 2f8dA-4xngA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4xng UNCHARACTERIZED
PROTEIN MG218.1
(Mycoplasma
genitalium) 		5 / 10 LEU A 138
ILE A 134
LEU A 181
ARG A 182
ILE A 178
 None
 0.99A 2f8dB-4xngA:
undetectable		 2f8dB-4xngA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4xng UNCHARACTERIZED
PROTEIN MG218.1
(Mycoplasma
genitalium) 		4 / 4 LEU A  89
LEU A  95
GLN A 183
GLU A 132
 None
 1.27A 4i41A-4xngA:
undetectable		 4i41A-4xngA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 4xng UNCHARACTERIZED
PROTEIN MG218.1
(Mycoplasma
genitalium) 		4 / 6 LEU A  84
LEU A 154
PHE A  81
ILE A 141
 None
 0.97A 4y4dA-4xngA:
undetectable		 4y4dA-4xngA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 4xng UNCHARACTERIZED
PROTEIN MG218.1
(Mycoplasma
genitalium) 		4 / 7 ILE A 179
THR A 131
ILE A 135
PHE A  81
 None
 0.82A 5fukA-4xngA:
undetectable
5fukB-4xngA:
undetectable		 5fukA-4xngA:
23.81
5fukB-4xngA:
23.81