SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xoh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 4xoh DIVISION MAL FOUTUE
1 PROTEIN
(Schizosaccharomy
ces
pombe) 		3 / 3 ASN C  40
PHE C  60
VAL C  34
 None
 0.82A 1kijA-4xohC:
undetectable		 1kijA-4xohC:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 4xoh DIVISION MAL FOUTUE
1 PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 8 THR C 167
GLY C 123
THR C 124
ALA C 125
 None
 0.88A 2a1hA-4xohC:
undetectable
2a1hB-4xohC:
undetectable		 2a1hA-4xohC:
22.64
2a1hB-4xohC:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 4xoh DIVISION MAL FOUTUE
1 PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 7 ASP C  63
PHE C  66
PRO C  37
THR C  38
 None
 1.46A 2q6kA-4xohC:
undetectable		 2q6kA-4xohC:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 4xoh DIVISION MAL FOUTUE
1 PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 6 ASP C  63
PHE C  66
PRO C  37
THR C  38
 None
 1.43A 2q6oB-4xohC:
undetectable		 2q6oB-4xohC:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 4xoh DIVISION MAL FOUTUE
1 PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 8 MET C 301
LEU C 249
ARG C 215
VAL C 226
 None
 1.20A 2qd2A-4xohC:
undetectable		 2qd2A-4xohC:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4xoh DIVISION MAL FOUTUE
1 PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 5 PHE C  60
ILE C  13
PHE C  11
PHE C  66
 None
 0.83A 3owxB-4xohC:
undetectable		 3owxB-4xohC:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 4xoh DIVISION MAL FOUTUE
1 PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 7 LEU C 176
PHE C 141
PHE C  70
LEU C 173
 None
 1.20A 6aycA-4xohC:
undetectable		 6aycA-4xohC:
13.56