SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xrl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DRE_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 12	ALA A 305 MET A 291 LEU A 135 ILE A 215 LEU A 153	None	1.11A	1dreA-4xrlA: undetectable	1dreA-4xrlA: 18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RX3_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 12	ALA A 305 MET A 291 LEU A 135 ILE A 215 LEU A 153	None	1.13A	1rx3A-4xrlA: undetectable	1rx3A-4xrlA: 18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 7	ASP A 316 ASP A 319 LYS A 136 HIS A 78	None	1.33A	1t03A-4xrlA: undetectable	1t03A-4xrlA: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TDN_A_LEUA487_0 (L-AMINO ACID OXIDASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 7	ASN A 152 HIS A 145 PHE A 166 ILE A 131	None	1.35A	1tdnA-4xrlA: undetectable	1tdnA-4xrlA: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWH_A_BAXA1723_2 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 6	ILE A 29 VAL A 37 ILE A 81 ASP A 165	42A A 402 ( 4.7A) None None None	0.62A	1uwhA-4xrlA: 22.3	1uwhA-4xrlA: 27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWJ_A_BAXA1723_2 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 7	ILE A 29 LEU A 73 ILE A 81 ASP A 165	42A A 402 ( 4.7A) None None None	0.85A	1uwjA-4xrlA: 21.9	1uwjA-4xrlA: 27.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_A_B49A1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	7 / 12	ILE A 29 VAL A 37 ALA A 50 ILE A 82 LEU A 105 MET A 106 LEU A 154	42A A 402 ( 4.7A) None 42A A 402 (-3.2A) None 42A A 402 ( 4.9A) None 42A A 402 ( 4.9A)	0.61A	2y7jA-4xrlA: 28.1	2y7jA-4xrlA: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_B_B49B1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	7 / 10	ILE A 29 VAL A 37 ALA A 50 ILE A 82 LEU A 105 MET A 106 LEU A 154	42A A 402 ( 4.7A) None 42A A 402 (-3.2A) None 42A A 402 ( 4.9A) None 42A A 402 ( 4.9A)	0.58A	2y7jB-4xrlA: 28.1	2y7jB-4xrlA: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_C_B49C1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	7 / 10	ILE A 29 VAL A 37 ALA A 50 ILE A 82 LEU A 105 MET A 106 LEU A 154	42A A 402 ( 4.7A) None 42A A 402 (-3.2A) None 42A A 402 ( 4.9A) None 42A A 402 ( 4.9A)	0.61A	2y7jC-4xrlA: 28.1	2y7jC-4xrlA: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_D_B49D1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	7 / 10	ILE A 29 VAL A 37 ALA A 50 ILE A 82 LEU A 105 MET A 106 LEU A 154	42A A 402 ( 4.7A) None 42A A 402 (-3.2A) None 42A A 402 ( 4.9A) None 42A A 402 ( 4.9A)	0.56A	2y7jD-4xrlA: 28.1	2y7jD-4xrlA: 24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_C_VD3C2001_1 (VITAMIN D HYDROXYLASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 11	ILE A 124 LEU A 153 LEU A 216 ILE A 215 LEU A 114	None	1.25A	3a50C-4xrlA: undetectable	3a50C-4xrlA: 19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_F_SVRF509_3 (PHOSPHOLIPASE A2)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 7	VAL A 171 ILE A 138 GLY A 134 LEU A 306	None	0.91A	3bjwF-4xrlA: undetectable	3bjwF-4xrlA: 13.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GCS_A_BAXA401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	6 / 12	VAL A 37 ALA A 50 GLU A 69 LEU A 73 ILE A 82 ILE A 138	None 42A A 402 (-3.2A) None None None None	1.08A	3gcsA-4xrlA: 35.6	3gcsA-4xrlA: 46.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GCS_A_BAXA401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 12	VAL A 37 ALA A 50 ILE A 82 ILE A 138 HIS A 145	None 42A A 402 (-3.2A) None None None	0.88A	3gcsA-4xrlA: 35.6	3gcsA-4xrlA: 46.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HEG_A_BAXA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	7 / 12	VAL A 37 ALA A 50 LYS A 52 GLU A 69 LEU A 73 ILE A 82 ILE A 138	None 42A A 402 (-3.2A) 42A A 402 (-4.1A) None None None None	1.16A	3hegA-4xrlA: 36.9	3hegA-4xrlA: 48.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LFA_A_1N1A361_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 8	ALA A 50 LYS A 52 GLU A 69 LEU A 105 MET A 106	42A A 402 (-3.2A) 42A A 402 (-4.1A) None 42A A 402 ( 4.9A) None	0.89A	3lfaA-4xrlA: 36.4	3lfaA-4xrlA: 46.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 7	SER A 211 LEU A 239 ILE A 225 PHE A 226	None	1.09A	3ln1C-4xrlA: undetectable	3ln1C-4xrlA: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MIY_B_B49B2_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 9	ILE A 29 ALA A 50 LYS A 52 MET A 106 LEU A 154	42A A 402 ( 4.7A) 42A A 402 (-3.2A) 42A A 402 (-4.1A) None 42A A 402 ( 4.9A)	0.58A	3miyB-4xrlA: 17.2	3miyB-4xrlA: 26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MJR_A_AC2A301_1 (DEOXYCYTIDINE KINASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 9	ILE A 253 GLU A 195 ARG A 299 PHE A 294 LEU A 250	None	1.15A	3mjrA-4xrlA: undetectable	3mjrA-4xrlA: 22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QL0_A_FOLA160_0 (DIHYDROFOLATE REDUCTASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 12	ALA A 305 MET A 291 LEU A 135 ILE A 215 LEU A 153	None	1.17A	3ql0A-4xrlA: undetectable	3ql0A-4xrlA: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFN_A_ROCA401_2 (HIV-1 PROTEASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 7	ASP A 86 GLY A 20 VAL A 49 VAL A 102	None	0.72A	3ufnB-4xrlA: undetectable	3ufnB-4xrlA: 13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOS_A_0LIA1000_2 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 9	ILE A 72 ILE A 81 ILE A 82 MET A 106 ILE A 163	None	0.91A	3zosA-4xrlA: 20.9	3zosA-4xrlA: 26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A6E_A_SAMA1349_1 (HYDROXYINDOLE O-METHYLTRANSFERASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	3 / 3	TYR A 314 ASP A 122 ASP A 281	None	0.88A	4a6eA-4xrlA: undetectable	4a6eA-4xrlA: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AQL_A_TXCA1452_2 (GUANINE DEAMINASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 5	HIS A 139 LEU A 292 LEU A 216 ASP A 289	None	0.97A	4aqlA-4xrlA: undetectable	4aqlA-4xrlA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ASD_A_BAXA1500_2 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 6	ILE A 72 LEU A 154 ILE A 163 CYH A 164	None 42A A 402 ( 4.9A) None None	0.87A	4asdA-4xrlA: 20.9	4asdA-4xrlA: 25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_A_0LIA1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	7 / 12	ALA A 50 LYS A 52 LEU A 73 ILE A 101 HIS A 145 LEU A 154 ASP A 165	42A A 402 (-3.2A) 42A A 402 (-4.1A) None None None 42A A 402 ( 4.9A) None	0.96A	4c8bA-4xrlA: 22.1	4c8bA-4xrlA: 27.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_A_0LIA1000_2 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 5	VAL A 37 ILE A 81 MET A 106 ILE A 163	None	0.69A	4c8bA-4xrlA: 22.1	4c8bA-4xrlA: 27.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I41_A_MIXA500_1 (SERINE/THREONINE-PRO TEIN KINASE PIM-1)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	8 / 12	VAL A 37 ALA A 50 ILE A 82 ASP A 109 ASP A 147 LYS A 149 ASN A 152 LEU A 154	None 42A A 402 (-3.2A) None None None None None 42A A 402 ( 4.9A)	1.05A	4i41A-4xrlA: 25.1	4i41A-4xrlA: 25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IMA_D_ADND604_1 (PYRUVATE KINASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	3 / 3	ARG A 133 GLU A 79 ASN A 80	None	0.71A	4imaD-4xrlA: undetectable	4imaD-4xrlA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IP7_D_ADND604_1 (PYRUVATE KINASE ISOZYMES L)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	3 / 3	ARG A 133 GLU A 79 ASN A 80	None	0.68A	4ip7D-4xrlA: undetectable	4ip7D-4xrlA: 19.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OGR_E_ADNE401_1 (CYCLIN-DEPENDENT KINASE 9)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 7	ASP A 109 ASN A 152 LEU A 154 ASP A 165	None None 42A A 402 ( 4.9A) None	0.33A	4ogrE-4xrlA: 30.8	4ogrE-4xrlA: 33.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMN_A_DB8A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	6 / 12	ILE A 29 ALA A 50 GLU A 69 ILE A 101 LEU A 154 ASP A 165	42A A 402 ( 4.7A) 42A A 402 (-3.2A) None None 42A A 402 ( 4.9A) None	0.81A	4qmnA-4xrlA: 26.7	4qmnA-4xrlA: 27.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RZ7_A_1E8A901_1 (CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 10	ILE A 29 ALA A 50 ILE A 82 LEU A 105 LEU A 154	42A A 402 ( 4.7A) 42A A 402 (-3.2A) None 42A A 402 ( 4.9A) 42A A 402 ( 4.9A)	0.75A	4rz7A-4xrlA: 8.3	4rz7A-4xrlA: 16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U0I_A_0LIA1001_2 (MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT,MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	7 / 12	ALA A 50 LYS A 52 LEU A 73 HIS A 145 LEU A 154 CYH A 164 ASP A 165	42A A 402 (-3.2A) 42A A 402 (-4.1A) None None 42A A 402 ( 4.9A) None None	0.99A	4u0iA-4xrlA: 21.3	4u0iA-4xrlA: 25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WAN_C_ACTC303_0 (BRANCHPOINT-BRIDGING PROTEIN)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	3 / 3	ASP A 177 ARG A 299 PRO A 296	None	0.66A	4wanC-4xrlA: undetectable	4wanC-4xrlA: 17.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 6	ALA A 50 GLN A 103 LEU A 105 MET A 106 LEU A 154	42A A 402 (-3.2A) 42A A 402 (-3.9A) 42A A 402 ( 4.9A) None 42A A 402 ( 4.9A)	0.19A	4xoyA-4xrlA: 49.7	4xoyA-4xrlA: 99.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 6	ALA A 50 GLN A 103 LEU A 105 MET A 106 LEU A 154	42A A 402 (-3.2A) 42A A 402 (-3.9A) 42A A 402 ( 4.9A) None 42A A 402 ( 4.9A)	0.24A	4xp3A-4xrlA: 51.8	4xp3A-4xrlA: 99.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XT8_A_TMQA302_1 (RV2671)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 12	ILE A 54 GLY A 35 ALA A 33 GLU A 58 THR A 66	None	1.30A	4xt8A-4xrlA: undetectable	4xt8A-4xrlA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUE_B_SAMB303_0 (CATECHOL O-METHYLTRANSFERASE)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 12	MET A 106 VAL A 49 GLY A 83 ILE A 81 ASN A 80	None	1.34A	4xueB-4xrlA: undetectable	4xueB-4xrlA: 20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A5Z_A_WJZA304_0 (BETA-LACTAMASE NDM-1)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 8	VAL A 302 HIS A 145 ASP A 208 HIS A 139	None	0.91A	5a5zA-4xrlA: undetectable	5a5zA-4xrlA: 19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_Y_BEZY801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	4 / 5	ILE A 70 GLY A 83 ILE A 87 LEU A 73	None	0.92A	5dzkd-4xrlA: undetectable 5dzkk-4xrlA: undetectable 5dzky-4xrlA: undetectable	5dzkd-4xrlA: 20.46 5dzkk-4xrlA: 22.10 5dzky-4xrlA: 3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_B_ADNB401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 9	ILE A 29 GLY A 30 VAL A 37 ALA A 50 MET A 106	42A A 402 ( 4.7A) None None 42A A 402 (-3.2A) None	0.73A	5lw1B-4xrlA: 36.9	5lw1B-4xrlA: 10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_B_ADNB401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 9	ILE A 29 VAL A 37 ALA A 50 ILE A 82 MET A 106	42A A 402 ( 4.7A) None 42A A 402 (-3.2A) None None	0.69A	5lw1B-4xrlA: 36.9	5lw1B-4xrlA: 10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_E_ADNE401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 10	GLY A 30 VAL A 37 ALA A 50 LEU A 105 MET A 106	None None 42A A 402 (-3.2A) 42A A 402 ( 4.9A) None	0.67A	5lw1E-4xrlA: 36.4	5lw1E-4xrlA: 10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_E_ADNE401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 10	VAL A 37 ALA A 50 ILE A 82 LEU A 105 MET A 106	None 42A A 402 (-3.2A) None 42A A 402 ( 4.9A) None	0.64A	5lw1E-4xrlA: 36.4	5lw1E-4xrlA: 10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_H_ADNH401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	5 / 9	GLY A 30 VAL A 37 ALA A 50 LEU A 105 MET A 106	None None 42A A 402 (-3.2A) 42A A 402 ( 4.9A) None	0.58A	5lw1H-4xrlA: 37.2	5lw1H-4xrlA: 10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FNM_A_1N1A1001_1 (-)	4xrl	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	8 / 12	ILE A 29 VAL A 37 ALA A 50 LYS A 52 GLU A 69 ILE A 101 MET A 106 LEU A 154	42A A 402 ( 4.7A) None 42A A 402 (-3.2A) 42A A 402 (-4.1A) None None None 42A A 402 ( 4.9A)	0.76A	6fnmA-4xrlA: 23.5	6fnmA-4xrlA: 27.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DRE_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ALA A 305;MET A 291;LEU A 135;ILE A 215;LEU A 153","None","1.11A","1dreA-4xrlA:undetectable","1dreA-4xrlA:18.50"],["1RX3_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ALA A 305;MET A 291;LEU A 135;ILE A 215;LEU A 153","None","1.13A","1rx3A-4xrlA:undetectable","1rx3A-4xrlA:18.50"],["1T03_P_TFOP822_1","POL POLYPROTEIN;SYNTHETIC OLIGONUCLEOTIDE PRIMER","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"ASP A 316;ASP A 319;LYS A 136;HIS A  78","None","1.33A","1t03A-4xrlA:undetectable","1t03A-4xrlA:19.82"],["1TDN_A_LEUA487_0","L-AMINO ACID OXIDASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"ASN A 152;HIS A 145;PHE A 166;ILE A 131","None","1.35A","1tdnA-4xrlA:undetectable","1tdnA-4xrlA:22.38"],["1UWH_A_BAXA1723_2","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"ILE A  29;VAL A  37;ILE A  81;ASP A 165","42A A 402 ( 4.7A);None;None;None","0.62A","1uwhA-4xrlA:22.3","1uwhA-4xrlA:27.91"],["1UWJ_A_BAXA1723_2","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"ILE A  29;LEU A  73;ILE A  81;ASP A 165","42A A 402 ( 4.7A);None;None;None","0.85A","1uwjA-4xrlA:21.9","1uwjA-4xrlA:27.33"],["2Y7J_A_B49A1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",7,"ILE A  29;VAL A  37;ALA A  50;ILE A  82;LEU A 105;MET A 106;LEU A 154","42A A 402 ( 4.7A);None;42A A 402 (-3.2A);None;42A A 402 ( 4.9A);None;42A A 402 ( 4.9A)","0.61A","2y7jA-4xrlA:28.1","2y7jA-4xrlA:24.57"],["2Y7J_B_B49B1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",7,"ILE A  29;VAL A  37;ALA A  50;ILE A  82;LEU A 105;MET A 106;LEU A 154","42A A 402 ( 4.7A);None;42A A 402 (-3.2A);None;42A A 402 ( 4.9A);None;42A A 402 ( 4.9A)","0.58A","2y7jB-4xrlA:28.1","2y7jB-4xrlA:24.57"],["2Y7J_C_B49C1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",7,"ILE A  29;VAL A  37;ALA A  50;ILE A  82;LEU A 105;MET A 106;LEU A 154","42A A 402 ( 4.7A);None;42A A 402 (-3.2A);None;42A A 402 ( 4.9A);None;42A A 402 ( 4.9A)","0.61A","2y7jC-4xrlA:28.1","2y7jC-4xrlA:24.57"],["2Y7J_D_B49D1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",7,"ILE A  29;VAL A  37;ALA A  50;ILE A  82;LEU A 105;MET A 106;LEU A 154","42A A 402 ( 4.7A);None;42A A 402 (-3.2A);None;42A A 402 ( 4.9A);None;42A A 402 ( 4.9A)","0.56A","2y7jD-4xrlA:28.1","2y7jD-4xrlA:24.57"],["3A50_C_VD3C2001_1","VITAMIN D HYDROXYLASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ILE A 124;LEU A 153;LEU A 216;ILE A 215;LEU A 114","None","1.25A","3a50C-4xrlA:undetectable","3a50C-4xrlA:19.81"],["3BJW_F_SVRF509_3","PHOSPHOLIPASE A2","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"VAL A 171;ILE A 138;GLY A 134;LEU A 306","None","0.91A","3bjwF-4xrlA:undetectable","3bjwF-4xrlA:13.45"],["3GCS_A_BAXA401_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",6,"VAL A  37;ALA A  50;GLU A  69;LEU A  73;ILE A  82;ILE A 138","None;42A A 402 (-3.2A);None;None;None;None","1.08A","3gcsA-4xrlA:35.6","3gcsA-4xrlA:46.41"],["3GCS_A_BAXA401_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"VAL A  37;ALA A  50;ILE A  82;ILE A 138;HIS A 145","None;42A A 402 (-3.2A);None;None;None","0.88A","3gcsA-4xrlA:35.6","3gcsA-4xrlA:46.41"],["3HEG_A_BAXA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",7,"VAL A  37;ALA A  50;LYS A  52;GLU A  69;LEU A  73;ILE A  82;ILE A 138","None;42A A 402 (-3.2A);42A A 402 (-4.1A);None;None;None;None","1.16A","3hegA-4xrlA:36.9","3hegA-4xrlA:48.15"],["3LFA_A_1N1A361_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ALA A  50;LYS A  52;GLU A  69;LEU A 105;MET A 106","42A A 402 (-3.2A);42A A 402 (-4.1A);None;42A A 402 ( 4.9A);None","0.89A","3lfaA-4xrlA:36.4","3lfaA-4xrlA:46.96"],["3LN1_C_CELC682_2","PROSTAGLANDIN G\/H SYNTHASE 2","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"SER A 211;LEU A 239;ILE A 225;PHE A 226","None","1.09A","3ln1C-4xrlA:undetectable","3ln1C-4xrlA:20.27"],["3MIY_B_B49B2_1","TYROSINE-PROTEIN KINASE ITK\/TSK","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ILE A  29;ALA A  50;LYS A  52;MET A 106;LEU A 154","42A A 402 ( 4.7A);42A A 402 (-3.2A);42A A 402 (-4.1A);None;42A A 402 ( 4.9A)","0.58A","3miyB-4xrlA:17.2","3miyB-4xrlA:26.96"],["3MJR_A_AC2A301_1","DEOXYCYTIDINE KINASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ILE A 253;GLU A 195;ARG A 299;PHE A 294;LEU A 250","None","1.15A","3mjrA-4xrlA:undetectable","3mjrA-4xrlA:22.95"],["3QL0_A_FOLA160_0","DIHYDROFOLATE REDUCTASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ALA A 305;MET A 291;LEU A 135;ILE A 215;LEU A 153","None","1.17A","3ql0A-4xrlA:undetectable","3ql0A-4xrlA:18.66"],["3UFN_A_ROCA401_2","HIV-1 PROTEASE;HIV-1 PROTEASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"ASP A  86;GLY A  20;VAL A  49;VAL A 102","None","0.72A","3ufnB-4xrlA:undetectable","3ufnB-4xrlA:13.31"],["3ZOS_A_0LIA1000_2","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ILE A  72;ILE A  81;ILE A  82;MET A 106;ILE A 163","None","0.91A","3zosA-4xrlA:20.9","3zosA-4xrlA:26.05"],["4A6E_A_SAMA1349_1","HYDROXYINDOLE O-METHYLTRANSFERASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",3,"TYR A 314;ASP A 122;ASP A 281","None","0.88A","4a6eA-4xrlA:undetectable","4a6eA-4xrlA:21.88"],["4AQL_A_TXCA1452_2","GUANINE DEAMINASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"HIS A 139;LEU A 292;LEU A 216;ASP A 289","None","0.97A","4aqlA-4xrlA:undetectable","4aqlA-4xrlA:22.52"],["4ASD_A_BAXA1500_2","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"ILE A  72;LEU A 154;ILE A 163;CYH A 164","None;42A A 402 ( 4.9A);None;None","0.87A","4asdA-4xrlA:20.9","4asdA-4xrlA:25.71"],["4C8B_A_0LIA1000_1","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",7,"ALA A  50;LYS A  52;LEU A  73;ILE A 101;HIS A 145;LEU A 154;ASP A 165","42A A 402 (-3.2A);42A A 402 (-4.1A);None;None;None;42A A 402 ( 4.9A);None","0.96A","4c8bA-4xrlA:22.1","4c8bA-4xrlA:27.32"],["4C8B_A_0LIA1000_2","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"VAL A  37;ILE A  81;MET A 106;ILE A 163","None","0.69A","4c8bA-4xrlA:22.1","4c8bA-4xrlA:27.32"],["4I41_A_MIXA500_1","SERINE\/THREONINE-PROTEIN KINASE PIM-1","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",8,"VAL A  37;ALA A  50;ILE A  82;ASP A 109;ASP A 147;LYS A 149;ASN A 152;LEU A 154","None;42A A 402 (-3.2A);None;None;None;None;None;42A A 402 ( 4.9A)","1.05A","4i41A-4xrlA:25.1","4i41A-4xrlA:25.47"],["4IMA_D_ADND604_1","PYRUVATE KINASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",3,"ARG A 133;GLU A  79;ASN A  80","None","0.71A","4imaD-4xrlA:undetectable","4imaD-4xrlA:18.84"],["4IP7_D_ADND604_1","PYRUVATE KINASE ISOZYMES L","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",3,"ARG A 133;GLU A  79;ASN A  80","None","0.68A","4ip7D-4xrlA:undetectable","4ip7D-4xrlA:19.02"],["4OGR_E_ADNE401_1","CYCLIN-DEPENDENT KINASE 9","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"ASP A 109;ASN A 152;LEU A 154;ASP A 165","None;None;42A A 402 ( 4.9A);None","0.33A","4ogrE-4xrlA:30.8","4ogrE-4xrlA:33.06"],["4QMN_A_DB8A401_1","SERINE\/THREONINE-PROTEIN KINASE 24","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",6,"ILE A  29;ALA A  50;GLU A  69;ILE A 101;LEU A 154;ASP A 165","42A A 402 ( 4.7A);42A A 402 (-3.2A);None;None;42A A 402 ( 4.9A);None","0.81A","4qmnA-4xrlA:26.7","4qmnA-4xrlA:27.45"],["4RZ7_A_1E8A901_1","CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ILE A  29;ALA A  50;ILE A  82;LEU A 105;LEU A 154","42A A 402 ( 4.7A);42A A 402 (-3.2A);None;42A A 402 ( 4.9A);42A A 402 ( 4.9A)","0.75A","4rz7A-4xrlA:8.3","4rz7A-4xrlA:16.19"],["4U0I_A_0LIA1001_2","MAST\/STEM CELL GROWTH FACTOR RECEPTOR KIT,MAST\/STEM CELL GROWTH FACTOR RECEPTOR KIT","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",7,"ALA A  50;LYS A  52;LEU A  73;HIS A 145;LEU A 154;CYH A 164;ASP A 165","42A A 402 (-3.2A);42A A 402 (-4.1A);None;None;42A A 402 ( 4.9A);None;None","0.99A","4u0iA-4xrlA:21.3","4u0iA-4xrlA:25.39"],["4WAN_C_ACTC303_0","BRANCHPOINT-BRIDGING PROTEIN","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",3,"ASP A 177;ARG A 299;PRO A 296","None","0.66A","4wanC-4xrlA:undetectable","4wanC-4xrlA:17.29"],["4XOY_A_DX4A401_0","MITOGEN-ACTIVATED PROTEIN KINASE 1","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ALA A  50;GLN A 103;LEU A 105;MET A 106;LEU A 154","42A A 402 (-3.2A);42A A 402 (-3.9A);42A A 402 ( 4.9A);None;42A A 402 ( 4.9A)","0.19A","4xoyA-4xrlA:49.7","4xoyA-4xrlA:99.42"],["4XP3_A_DX4A401_0","MITOGEN-ACTIVATED PROTEIN KINASE 1","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ALA A  50;GLN A 103;LEU A 105;MET A 106;LEU A 154","42A A 402 (-3.2A);42A A 402 (-3.9A);42A A 402 ( 4.9A);None;42A A 402 ( 4.9A)","0.24A","4xp3A-4xrlA:51.8","4xp3A-4xrlA:99.42"],["4XT8_A_TMQA302_1","RV2671","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ILE A  54;GLY A  35;ALA A  33;GLU A  58;THR A  66","None","1.30A","4xt8A-4xrlA:undetectable","4xt8A-4xrlA:20.17"],["4XUE_B_SAMB303_0","CATECHOL O-METHYLTRANSFERASE","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"MET A 106;VAL A  49;GLY A  83;ILE A  81;ASN A  80","None","1.34A","4xueB-4xrlA:undetectable","4xueB-4xrlA:20.52"],["5A5Z_A_WJZA304_0","BETA-LACTAMASE NDM-1","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"VAL A 302;HIS A 145;ASP A 208;HIS A 139","None","0.91A","5a5zA-4xrlA:undetectable","5a5zA-4xrlA:19.36"],["5DZK_Y_BEZY801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",4,"ILE A  70;GLY A  83;ILE A  87;LEU A  73","None","0.92A","5dzkd-4xrlA:undetectable;5dzkk-4xrlA:undetectable;5dzky-4xrlA:undetectable","5dzkd-4xrlA:20.46;5dzkk-4xrlA:22.10;5dzky-4xrlA:3.03"],["5LW1_B_ADNB401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ILE A  29;GLY A  30;VAL A  37;ALA A  50;MET A 106","42A A 402 ( 4.7A);None;None;42A A 402 (-3.2A);None","0.73A","5lw1B-4xrlA:36.9","5lw1B-4xrlA:10.94"],["5LW1_B_ADNB401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"ILE A  29;VAL A  37;ALA A  50;ILE A  82;MET A 106","42A A 402 ( 4.7A);None;42A A 402 (-3.2A);None;None","0.69A","5lw1B-4xrlA:36.9","5lw1B-4xrlA:10.94"],["5LW1_E_ADNE401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"GLY A  30;VAL A  37;ALA A  50;LEU A 105;MET A 106","None;None;42A A 402 (-3.2A);42A A 402 ( 4.9A);None","0.67A","5lw1E-4xrlA:36.4","5lw1E-4xrlA:10.94"],["5LW1_E_ADNE401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"VAL A  37;ALA A  50;ILE A  82;LEU A 105;MET A 106","None;42A A 402 (-3.2A);None;42A A 402 ( 4.9A);None","0.64A","5lw1E-4xrlA:36.4","5lw1E-4xrlA:10.94"],["5LW1_H_ADNH401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",5,"GLY A  30;VAL A  37;ALA A  50;LEU A 105;MET A 106","None;None;42A A 402 (-3.2A);42A A 402 ( 4.9A);None","0.58A","5lw1H-4xrlA:37.2","5lw1H-4xrlA:10.94"],["6FNM_A_1N1A1001_1","-","4xrl","MITOGEN-ACTIVATED PROTEIN KINASE 1","Rattus norvegicus",8,"ILE A  29;VAL A  37;ALA A  50;LYS A  52;GLU A  69;ILE A 101;MET A 106;LEU A 154","42A A 402 ( 4.7A);None;42A A 402 (-3.2A);42A A 402 (-4.1A);None;None;None;42A A 402 ( 4.9A)","0.76A","6fnmA-4xrlA:23.5","6fnmA-4xrlA:27.40"]]