SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xrn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARR_A_PNXA606_1 (CHITINASE A)	4xrn	ALGINATE BIOSYNTHESIS PROTEIN ALG44 (Pseudomonas aeruginosa)	4 / 7	GLY A 21 ASP A 28 TYR A 19 ARG A 16	None ZN A 205 ( 1.9A) None None	0.94A	3arrA-4xrnA: 2.2	3arrA-4xrnA: 11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARU_A_PNXA606_1 (CHITINASE A)	4xrn	ALGINATE BIOSYNTHESIS PROTEIN ALG44 (Pseudomonas aeruginosa)	4 / 7	GLY A 21 ASP A 28 TYR A 19 ARG A 16	None ZN A 205 ( 1.9A) None None	0.98A	3aruA-4xrnA: undetectable	3aruA-4xrnA: 11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA411_0 (UNCHARACTERIZED PROTEIN KDOO)	4xrn	ALGINATE BIOSYNTHESIS PROTEIN ALG44 (Pseudomonas aeruginosa)	3 / 3	LYS A 57 LEU A 59 ARG A 18	None	0.91A	5yw0A-4xrnA: undetectable	5yw0A-4xrnA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4xrn	ALGINATE BIOSYNTHESIS PROTEIN ALG44 (Pseudomonas aeruginosa)	3 / 3	ARG A 18 LEU A 59 PHE A 60	None	0.72A	6nknP-4xrnA: undetectable	6nknP-4xrnA: 18.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ARR_A_PNXA606_1","CHITINASE A","4xrn","ALGINATE BIOSYNTHESIS PROTEIN ALG44","Pseudomonas aeruginosa",4,"GLY A  21;ASP A  28;TYR A  19;ARG A  16","None; ZN A 205 ( 1.9A);None;None","0.94A","3arrA-4xrnA:2.2","3arrA-4xrnA:11.82"],["3ARU_A_PNXA606_1","CHITINASE A","4xrn","ALGINATE BIOSYNTHESIS PROTEIN ALG44","Pseudomonas aeruginosa",4,"GLY A  21;ASP A  28;TYR A  19;ARG A  16","None; ZN A 205 ( 1.9A);None;None","0.98A","3aruA-4xrnA:undetectable","3aruA-4xrnA:11.82"],["5YW0_A_ACTA411_0","UNCHARACTERIZED PROTEIN KDOO","4xrn","ALGINATE BIOSYNTHESIS PROTEIN ALG44","Pseudomonas aeruginosa",3,"LYS A  57;LEU A  59;ARG A  18","None","0.91A","5yw0A-4xrnA:undetectable","5yw0A-4xrnA:16.14"],["6NKN_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4xrn","ALGINATE BIOSYNTHESIS PROTEIN ALG44","Pseudomonas aeruginosa",3,"ARG A  18;LEU A  59;PHE A  60","None","0.72A","6nknP-4xrnA:undetectable","6nknP-4xrnA:18.39"]]