SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xt0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	4xt0	PROTEIN LIGF (Sphingobium sp. SYK-6)	3 / 3	TRP A 115 ARG A 150 PHE A 155	None	1.39A	1zeaH-4xt0A: undetectable 1zeaL-4xt0A: undetectable	1zeaH-4xt0A: 21.15 1zeaL-4xt0A: 23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXF_A_DZPA2001_1 (SERUM ALBUMIN)	4xt0	PROTEIN LIGF (Sphingobium sp. SYK-6)	5 / 12	ILE A 194 LEU A 4 LEU A 56 GLU A 74 LEU A 73	None	1.09A	2bxfA-4xt0A: undetectable	2bxfA-4xt0A: 17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P7N_A_GCSA702_1 (POLY-BETA-1,6-N-ACET YL-D-GLUCOSAMINE N-DEACETYLASE)	4xt0	PROTEIN LIGF (Sphingobium sp. SYK-6)	3 / 3	ASP A 193 TYR A 189 TRP A 225	None	1.35A	4p7nA-4xt0A: undetectable	4p7nA-4xt0A: 19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4xt0	PROTEIN LIGF (Sphingobium sp. SYK-6)	4 / 4	VAL A 171 LEU A 174 LEU A 178 ASP A 193	None	1.47A	5xv7A-4xt0A: undetectable	5xv7A-4xt0A: 14.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZEA_A_DHIA6_0","MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN;MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN;SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2","4xt0","PROTEIN LIGF","Sphingobium sp. SYK-6",3,"TRP A 115;ARG A 150;PHE A 155","None","1.39A","1zeaH-4xt0A:undetectable;1zeaL-4xt0A:undetectable","1zeaH-4xt0A:21.15;1zeaL-4xt0A:23.74"],["2BXF_A_DZPA2001_1","SERUM ALBUMIN","4xt0","PROTEIN LIGF","Sphingobium sp. SYK-6",5,"ILE A 194;LEU A   4;LEU A  56;GLU A  74;LEU A  73","None","1.09A","2bxfA-4xt0A:undetectable","2bxfA-4xt0A:17.26"],["4P7N_A_GCSA702_1","POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE","4xt0","PROTEIN LIGF","Sphingobium sp. SYK-6",3,"ASP A 193;TYR A 189;TRP A 225","None","1.35A","4p7nA-4xt0A:undetectable","4p7nA-4xt0A:19.73"],["5XV7_A_EMHA705_2","SERINE-ARGININE (SR) PROTEIN KINASE 1","4xt0","PROTEIN LIGF","Sphingobium sp. SYK-6",4,"VAL A 171;LEU A 174;LEU A 178;ASP A 193","None","1.47A","5xv7A-4xt0A:undetectable","5xv7A-4xt0A:14.57"]]