SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xu4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q13_A_TESA501_1 (PROSTAGLANDIN-E2 9-REDUCTASE)	4xu4	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m vanbaalenii)	4 / 6	TYR A 150 HIS A 26 PRO A 103 VAL A 108	None DDQ A 303 (-4.3A) None None	1.00A	1q13A-4xu4A: undetectable	1q13A-4xu4A: 22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TJ7_D_ACTD605_0 (GBAA_1210 PROTEIN)	4xu4	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m vanbaalenii)	4 / 6	VAL A 28 HIS A 24 SER A 25 THR A 29	None	1.12A	3tj7C-4xu4A: undetectable 3tj7D-4xu4A: undetectable	3tj7C-4xu4A: 22.62 3tj7D-4xu4A: 22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XK8_A_PQNA845_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1)	4xu4	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m vanbaalenii)	4 / 8	PHE A 171 ALA A 61 LEU A 60 GLY A 172	DDQ A 303 (-3.5A) None None None	0.94A	4xk8a-4xu4A: undetectable	4xk8a-4xu4A: 13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X2T_I_PEMI202_1 (HEMOGLOBIN SUBUNIT ALPHA HEMOGLOBIN SUBUNIT BETA)	4xu4	UNCHARACTERIZED PROTEIN (Mycolicibacteriu m vanbaalenii)	4 / 8	ALA A 85 THR A 89 THR A 92 ALA A 106	BNG A 304 ( 3.7A) None None None	0.74A	5x2tI-4xu4A: undetectable 5x2tJ-4xu4A: undetectable 5x2tK-4xu4A: undetectable 5x2tL-4xu4A: undetectable	5x2tI-4xu4A: 20.95 5x2tJ-4xu4A: 24.19 5x2tK-4xu4A: 20.95 5x2tL-4xu4A: 24.19

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Q13_A_TESA501_1","PROSTAGLANDIN-E2 9-REDUCTASE","4xu4","UNCHARACTERIZED PROTEIN","Mycolicibacterium vanbaalenii",4,"TYR A 150;HIS A  26;PRO A 103;VAL A 108","None;DDQ A 303 (-4.3A);None;None","1.00A","1q13A-4xu4A:undetectable","1q13A-4xu4A:22.36"],["3TJ7_D_ACTD605_0","GBAA_1210 PROTEIN","4xu4","UNCHARACTERIZED PROTEIN","Mycolicibacterium vanbaalenii",4,"VAL A  28;HIS A  24;SER A  25;THR A  29","None","1.12A","3tj7C-4xu4A:undetectable;3tj7D-4xu4A:undetectable","3tj7C-4xu4A:22.62;3tj7D-4xu4A:22.62"],["4XK8_A_PQNA845_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1","4xu4","UNCHARACTERIZED PROTEIN","Mycolicibacterium vanbaalenii",4,"PHE A 171;ALA A  61;LEU A  60;GLY A 172","DDQ A 303 (-3.5A);None;None;None","0.94A","4xk8a-4xu4A:undetectable","4xk8a-4xu4A:13.61"],["5X2T_I_PEMI202_1","HEMOGLOBIN SUBUNIT ALPHA;HEMOGLOBIN SUBUNIT BETA;HEMOGLOBIN SUBUNIT ALPHA;HEMOGLOBIN SUBUNIT BETA","4xu4","UNCHARACTERIZED PROTEIN","Mycolicibacterium vanbaalenii",4,"ALA A  85;THR A  89;THR A  92;ALA A 106","BNG A 304 ( 3.7A);None;None;None","0.74A","5x2tI-4xu4A:undetectable;5x2tJ-4xu4A:undetectable;5x2tK-4xu4A:undetectable;5x2tL-4xu4A:undetectable","5x2tI-4xu4A:20.95;5x2tJ-4xu4A:24.19;5x2tK-4xu4A:20.95;5x2tL-4xu4A:24.19"]]