SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xuk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 9 VAL A 261
HIS A 248
THR A 293
THR A 241
ILE A 239
 None
 1.28A 1gtnL-4xukA:
undetectable
1gtnM-4xukA:
undetectable		 1gtnL-4xukA:
15.12
1gtnM-4xukA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 4 ALA A 280
VAL A 291
ALA A 290
HIS A 244
 None
None
None
ZN  A 402 (-3.3A)
 1.26A 1q23F-4xukA:
undetectable		 1q23F-4xukA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 4 ALA A 280
VAL A 291
ALA A 290
HIS A 244
 None
None
None
ZN  A 402 (-3.3A)
 1.20A 1q23K-4xukA:
undetectable		 1q23K-4xukA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 12 GLY A 305
ILE A 260
SER A 259
ALA A 309
ILE A 332
 None
 1.17A 1ve3A-4xukA:
undetectable		 1ve3A-4xukA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLX_A_CIOA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 12 HIS A 160
HIS A 155
LEU A 313
THR A  70
ILE A 105
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.5A)
None
None
None
 1.37A 1xlxA-4xukA:
undetectable		 1xlxA-4xukA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 9 ILE A 117
ASP A 149
GLY A 113
GLN A 234
THR A 150
 None
 1.04A 2dtjA-4xukA:
undetectable
2dtjB-4xukA:
undetectable		 2dtjA-4xukA:
20.61
2dtjB-4xukA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 12 LEU A 116
ILE A 117
VAL A  61
ALA A  58
ILE A 260
 None
 1.02A 2h42C-4xukA:
undetectable		 2h42C-4xukA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 12 TYR A  53
SER A 136
ALA A 140
GLY A  69
GLY A 132
 None
 1.16A 2igtA-4xukA:
undetectable		 2igtA-4xukA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 12 TYR A  53
SER A 136
ALA A 140
GLY A  69
GLY A 132
 None
 1.14A 2igtB-4xukA:
undetectable		 2igtB-4xukA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 12 ILE A 266
GLY A 243
HIS A 248
GLU A 183
SER A 180
 None
 1.21A 2pgfA-4xukA:
undetectable		 2pgfA-4xukA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 11 ASP A 159
HIS A 160
HIS A 244
ASP A 265
HIS A 312
 ZN  A 401 (-2.7A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 ( 2.5A)
ZN  A 401 (-3.4A)
 0.63A 2q0jB-4xukA:
15.5		 2q0jB-4xukA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 5 HIS A 244
HIS A 268
HIS A 312
ASP A 159
 ZN  A 402 (-3.3A)
None
ZN  A 401 (-3.4A)
ZN  A 401 (-2.7A)
 1.19A 3c0zA-4xukA:
undetectable		 3c0zA-4xukA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 8 HIS A 160
PHE A 108
ASP A 265
GLY A 264
 ZN  A 401 (-3.2A)
None
ZN  A 401 ( 2.5A)
None
 0.91A 3c0zB-4xukA:
undetectable		 3c0zB-4xukA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		3 / 3 ILE A 263
PHE A 298
HIS A 244
 None
None
ZN  A 402 (-3.3A)
 0.74A 3h0aA-4xukA:
undetectable		 3h0aA-4xukA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NJZ_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 12 HIS A 268
HIS A 244
HIS A 248
ASP A 120
ILE A 105
 None
ZN  A 402 (-3.3A)
None
None
None
 1.48A 3njzA-4xukA:
undetectable		 3njzA-4xukA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 10 ALA A 107
ILE A 105
GLY A 317
ILE A 318
LEU A  66
 None
 1.06A 3ogpA-4xukA:
undetectable		 3ogpA-4xukA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 10 HIS A 155
HIS A 157
ASP A 159
HIS A 244
HIS A 312
 ZN  A 402 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-2.7A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 4c1dB-4xukA:
15.2		 4c1dB-4xukA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 11 HIS A 155
HIS A 157
ASP A 159
HIS A 244
HIS A 312
 ZN  A 402 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-2.7A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 4c1fA-4xukA:
3.7
4c1fB-4xukA:
16.0		 4c1fA-4xukA:
21.89
4c1fB-4xukA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 9 HIS A 155
HIS A 157
ASP A 159
HIS A 244
HIS A 312
 ZN  A 402 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-2.7A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.4A)
 0.68A 4c1hA-4xukA:
5.2		 4c1hA-4xukA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_A_X8ZA301_1
(BETA-LACTAMASE NDM-1)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 9 MET A  73
HIS A 157
ASP A 159
HIS A 155
HIS A 312
 None
ZN  A 402 (-3.4A)
ZN  A 401 (-2.7A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.4A)
 1.31A 4exsA-4xukA:
3.2		 4exsA-4xukA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_A_X8ZA301_1
(BETA-LACTAMASE NDM-1)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 9 MET A  73
HIS A 157
ASP A 159
HIS A 244
HIS A 312
 None
ZN  A 402 (-3.4A)
ZN  A 401 (-2.7A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.4A)
 1.37A 4exsA-4xukA:
3.2		 4exsA-4xukA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 8 HIS A 157
ASP A 159
HIS A 244
HIS A 312
 ZN  A 402 (-3.4A)
ZN  A 401 (-2.7A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.4A)
 0.60A 4exsB-4xukA:
14.8		 4exsB-4xukA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_A_QI9A602_0
(CYTOCHROME P450 2D6)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 9 PHE A 236
LEU A 152
THR A 255
VAL A  61
VAL A 110
 None
 1.45A 4wnvA-4xukA:
undetectable		 4wnvA-4xukA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_B_QI9B602_0
(CYTOCHROME P450 2D6)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 9 PHE A 236
LEU A 152
THR A 255
VAL A  61
VAL A 110
 None
 1.45A 4wnvB-4xukA:
undetectable		 4wnvB-4xukA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_C_QI9C602_0
(CYTOCHROME P450 2D6)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 9 PHE A 236
LEU A 152
THR A 255
VAL A  61
VAL A 110
 None
 1.48A 4wnvC-4xukA:
undetectable		 4wnvC-4xukA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 12 GLY A 132
LEU A 131
ALA A 107
ASP A 120
PHE A 127
 None
 1.00A 4wnwB-4xukA:
undetectable		 4wnwB-4xukA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 7 ILE A 151
LEU A 153
TYR A 218
GLY A 163
 None
 0.98A 4z69A-4xukA:
undetectable		 4z69A-4xukA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 8 HIS A 157
ASP A 159
HIS A 244
HIS A 312
 ZN  A 402 (-3.4A)
ZN  A 401 (-2.7A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.4A)
 0.65A 5a5zA-4xukA:
3.0		 5a5zA-4xukA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		6 / 11 HIS A 155
HIS A 157
ASP A 159
HIS A 160
HIS A 244
HIS A 312
 ZN  A 402 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-2.7A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.4A)
 0.37A 5ayaA-4xukA:
16.0		 5ayaA-4xukA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 8 GLU A 183
HIS A 248
GLY A 243
HIS A 155
ASP A 265
 None
None
None
ZN  A 402 (-3.5A)
ZN  A 401 ( 2.5A)
 1.13A 5f8yA-4xukA:
undetectable		 5f8yA-4xukA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 8 GLU A 183
HIS A 248
GLY A 243
HIS A 155
ASP A 265
 None
None
None
ZN  A 402 (-3.5A)
ZN  A 401 ( 2.5A)
 1.14A 5f8yB-4xukA:
undetectable		 5f8yB-4xukA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		5 / 9 ALA A 107
ASP A 120
ILE A 151
GLY A 163
PRO A 145
 None
 1.23A 5kr2A-4xukA:
undetectable		 5kr2A-4xukA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 6 ASP A 265
HIS A 244
HIS A 155
HIS A 312
 ZN  A 401 ( 2.5A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.4A)
 0.93A 5ncdA-4xukA:
undetectable
5ncdD-4xukA:
undetectable		 5ncdA-4xukA:
19.60
5ncdD-4xukA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 6 ASP A 265
HIS A 244
HIS A 155
HIS A 312
 ZN  A 401 ( 2.5A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.4A)
 0.91A 5ncdB-4xukA:
undetectable
5ncdC-4xukA:
undetectable		 5ncdB-4xukA:
19.60
5ncdC-4xukA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 4 ASP A 265
HIS A 155
HIS A 157
HIS A 268
 ZN  A 401 ( 2.5A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.4A)
None
 1.49A 5ncdD-4xukA:
undetectable		 5ncdD-4xukA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 8 ASP A 265
HIS A 244
HIS A 155
HIS A 312
 ZN  A 401 ( 2.5A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.4A)
 0.85A 5nekD-4xukA:
undetectable		 5nekD-4xukA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 6 ASP A 265
HIS A 244
HIS A 155
HIS A 312
 ZN  A 401 ( 2.5A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.4A)
 0.91A 5nelA-4xukA:
undetectable
5nelD-4xukA:
undetectable		 5nelA-4xukA:
19.60
5nelD-4xukA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		6 / 10 HIS A 155
HIS A 157
HIS A 160
HIS A 244
ASP A 265
HIS A 268
 ZN  A 402 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 ( 2.5A)
None
 0.54A 5nzwA-4xukA:
3.3		 5nzwA-4xukA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		3 / 3 HIS A 160
ASP A 265
HIS A 312
 ZN  A 401 (-3.2A)
ZN  A 401 ( 2.5A)
ZN  A 401 (-3.4A)
 0.80A 5oexA-4xukA:
undetectable		 5oexA-4xukA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 4xuk PUTATIVE HYDROLASE
(Acinetobacter
sp.
NBRC
100985) 		4 / 8 HIS A 157
ASP A 159
HIS A 244
HIS A 312
 ZN  A 402 (-3.4A)
ZN  A 401 (-2.7A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.4A)
 0.64A 5zj8A-4xukA:
14.9		 5zj8A-4xukA:
24.92