SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xvh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.69A 1a7yA-4xvhA:
undetectable		 1a7yA-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.58A 1a7yB-4xvhA:
undetectable		 1a7yB-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.78A 1a7yB-4xvhA:
undetectable		 1a7yB-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.58A 1dscC-4xvhA:
undetectable		 1dscC-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.56A 1dscC-4xvhA:
undetectable		 1dscC-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.52A 1fjaC-4xvhA:
undetectable		 1fjaC-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.52A 1fjaD-4xvhA:
undetectable		 1fjaD-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.67A 1i3wE-4xvhA:
undetectable		 1i3wE-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.71A 1i3wE-4xvhA:
undetectable		 1i3wE-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.64A 1i3wF-4xvhA:
undetectable		 1i3wF-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.71A 1i3wG-4xvhA:
undetectable		 1i3wG-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.62A 1i3wG-4xvhA:
undetectable		 1i3wG-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.64A 1i3wH-4xvhA:
undetectable		 1i3wH-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.69A 1mnvD-4xvhA:
undetectable		 1mnvD-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.62A 1mnvD-4xvhA:
undetectable		 1mnvD-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.64A 1ovfB-4xvhA:
undetectable		 1ovfB-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		5 / 11 LEU A 235
MET A 258
TYR A 254
LEU A 276
GLN A 297
 None
 1.33A 1qabE-4xvhA:
undetectable		 1qabE-4xvhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.69A 1qfiA-4xvhA:
undetectable		 1qfiA-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.81A 1qfiB-4xvhA:
undetectable		 1qfiB-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 SER A  62
GLY A  63
ARG A 104
 None
PEU  A 402 ( 4.6A)
None
 0.62A 1t9wA-4xvhA:
undetectable		 1t9wA-4xvhA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.80A 1unjF-4xvhA:
undetectable		 1unjF-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.72A 1unjF-4xvhA:
undetectable		 1unjF-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.68A 1unjL-4xvhA:
undetectable		 1unjL-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.63A 1unjL-4xvhA:
undetectable		 1unjL-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.68A 1unjR-4xvhA:
undetectable		 1unjR-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.63A 1unjR-4xvhA:
undetectable		 1unjR-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.67A 1unjW-4xvhA:
undetectable		 1unjW-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.66A 1unjX-4xvhA:
undetectable		 1unjX-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.66A 1unjX-4xvhA:
undetectable		 1unjX-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.71A 1unmE-4xvhA:
undetectable		 1unmE-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.63A 1unmE-4xvhA:
undetectable		 1unmE-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.58A 1unmF-4xvhA:
undetectable		 1unmF-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.56A 1unmF-4xvhA:
undetectable		 1unmF-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 288
THR A 285
PRO A 287
 None
 0.63A 209dC-4xvhA:
undetectable		 209dC-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.71A 316dC-4xvhA:
undetectable		 316dC-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		5 / 12 VAL A  45
GLY A  44
GLY A  42
ASP A  68
ILE A  56
 None
 0.88A 3fuuA-4xvhA:
2.7		 3fuuA-4xvhA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 ARG A 246
ASP A 140
GLN A 320
 None
PEU  A 402 ( 4.2A)
None
 0.88A 3lcvB-4xvhA:
undetectable		 3lcvB-4xvhA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		4 / 6 THR A 237
ASN A 238
GLY A 188
ILE A 233
 None
PEU  A 402 (-2.8A)
None
None
 0.86A 3w9tF-4xvhA:
undetectable		 3w9tF-4xvhA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		3 / 3 THR A 285
PRO A 287
THR A 288
 None
 0.80A 4hivD-4xvhA:
undetectable		 4hivD-4xvhA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		5 / 12 VAL A  67
GLY A  86
GLY A  84
ILE A  56
LEU A  69
 None
 0.98A 4iv0A-4xvhA:
2.9		 4iv0A-4xvhA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		5 / 11 HIS A  98
THR A 120
SER A  24
ALA A  48
THR A 127
 None
 1.37A 4qvyV-4xvhA:
undetectable
4qvyb-4xvhA:
undetectable		 4qvyV-4xvhA:
22.02
4qvyb-4xvhA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		5 / 11 HIS A  98
THR A 120
SER A  24
ALA A  48
THR A 127
 None
 1.37A 4qvyH-4xvhA:
0.0
4qvyN-4xvhA:
undetectable		 4qvyH-4xvhA:
22.02
4qvyN-4xvhA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		5 / 11 HIS A  98
THR A 120
SER A  24
ALA A  48
THR A 127
 None
 1.39A 5l5fV-4xvhA:
undetectable
5l5fb-4xvhA:
undetectable		 5l5fV-4xvhA:
22.02
5l5fb-4xvhA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		5 / 11 HIS A  98
THR A 120
SER A  24
ALA A  48
THR A 127
 None
 1.39A 5l5fH-4xvhA:
undetectable
5l5fN-4xvhA:
undetectable		 5l5fH-4xvhA:
22.02
5l5fN-4xvhA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		5 / 12 ILE A  87
ILE A 118
VAL A  45
VAL A  61
LEU A  38
 None
 1.04A 6ajiA-4xvhA:
undetectable		 6ajiA-4xvhA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		5 / 12 HIS A 335
THR A 334
GLY A 325
HIS A 329
MET A 281
 None
None
None
PEU  A 402 ( 4.9A)
None
 1.32A 6exiD-4xvhA:
2.1		 6exiD-4xvhA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)
(Chaetomium) 		4 / 8 GLN A 134
TYR A 269
ILE A 265
VAL A 181
 None
 1.06A 6hu9a-4xvhA:
undetectable
6hu9e-4xvhA:
undetectable		 6hu9a-4xvhA:
21.55
6hu9e-4xvhA:
17.28