SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xwu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 6 ALA A 304
TRP A 292
ARG A 260
LEU A 276
 None
 1.15A 1gahA-4xwuA:
undetectable		 1gahA-4xwuA:
22.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		6 / 11 ASP A 277
SER A 278
SER A 279
ASN A 306
ARG A 325
MET A 328
 None
 0.64A 1jr1A-4xwuA:
47.2		 1jr1A-4xwuA:
52.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 8 ASP A 277
SER A 279
ASN A 306
ARG A 325
 None
 0.24A 1jr1B-4xwuA:
47.4		 1jr1B-4xwuA:
52.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 8 ASP A 277
SER A 278
SER A 279
ASN A 306
 None
 0.29A 1me7A-4xwuA:
38.6		 1me7A-4xwuA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 8 ASP A 277
SER A 278
SER A 279
ASN A 306
 None
 0.22A 1meiA-4xwuA:
38.9		 1meiA-4xwuA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 8 ILE A  94
GLY A 250
LEU A 271
LEU A 300
 None
 0.75A 2vctA-4xwuA:
undetectable		 2vctA-4xwuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 8 ILE A  94
GLY A 250
LEU A 271
LEU A 300
 None
 0.76A 2vctC-4xwuA:
undetectable		 2vctC-4xwuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 7 VAL A 370
GLN A 346
VAL A 350
ALA A 384
 None
 0.98A 3kp6B-4xwuA:
undetectable		 3kp6B-4xwuA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 8 ILE A 478
VAL A  43
THR A 377
ILE A 380
 None
 0.77A 3p4wC-4xwuA:
undetectable		 3p4wC-4xwuA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 7 GLY A 281
ASP A 277
VAL A 275
ILE A 326
 None
 0.59A 3t3cA-4xwuA:
undetectable		 3t3cA-4xwuA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 PHE A  71
PRO A  70
LEU A 483
VAL A  55
GLN A 472
 None
 1.31A 4a84A-4xwuA:
undetectable		 4a84A-4xwuA:
15.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		6 / 8 ASP A 277
SER A 278
SER A 279
ASN A 306
ARG A 325
MET A 328
 None
 0.14A 4af0A-4xwuA:
49.2		 4af0A-4xwuA:
53.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AF0_B_MOAB1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		6 / 10 ASP A 277
SER A 278
SER A 279
ASN A 306
ARG A 325
MET A 328
 None
 0.14A 4af0B-4xwuA:
49.2		 4af0B-4xwuA:
53.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 8 ASP A 277
SER A 278
SER A 279
ASN A 306
 None
 0.74A 4fo4A-4xwuA:
38.8		 4fo4A-4xwuA:
40.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		3 / 3 ASN A 469
SER A  52
SER A  53
 None
 0.72A 5gsnA-4xwuA:
undetectable		 5gsnA-4xwuA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 ARG A 111
LEU A 263
ALA A 252
GLY A 270
ALA A 269
 None
 0.89A 5jw1B-4xwuA:
undetectable		 5jw1B-4xwuA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 LEU A 276
VAL A 353
ARG A 325
ILE A 326
ASP A 367
 None
 1.40A 6bxnA-4xwuA:
undetectable		 6bxnA-4xwuA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 9 LEU A 471
SER A 474
ILE A 380
VAL A 387
ILE A 376
 None
 1.28A 6ef6A-4xwuA:
undetectable		 6ef6A-4xwuA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 VAL A 110
LEU A  61
LEU A  67
ALA A 251
LEU A 300
 None
 1.13A 6ew0B-4xwuA:
3.0		 6ew0B-4xwuA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 VAL A 110
LEU A  61
LEU A  67
ALA A 251
LEU A 300
 None
 1.13A 6ew0D-4xwuA:
3.0		 6ew0D-4xwuA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 VAL A 110
LEU A  61
LEU A  67
ALA A 251
LEU A 300
 None
 1.13A 6ew0H-4xwuA:
undetectable		 6ew0H-4xwuA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 VAL A 110
LEU A  61
LEU A  67
ALA A 251
LEU A 300
 None
 1.14A 6ew0I-4xwuA:
undetectable		 6ew0I-4xwuA:
11.70