SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4xzg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 4xzg HELICASE-LIKE
TRANSCRIPTION FACTOR
(Homo
sapiens) 		4 / 5 VAL A 160
LEU A 164
LEU A 171
ILE A 130
 None
 0.95A 4a9jA-4xzgA:
undetectable		 4a9jA-4xzgA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 4xzg HELICASE-LIKE
TRANSCRIPTION FACTOR
(Homo
sapiens) 		4 / 5 VAL A 160
LEU A 164
LEU A 171
ILE A 130
 None
 0.93A 4a9jB-4xzgA:
undetectable		 4a9jB-4xzgA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 4xzg HELICASE-LIKE
TRANSCRIPTION FACTOR
(Homo
sapiens) 		4 / 5 VAL A 160
LEU A 164
LEU A 171
ILE A 130
 None
 0.90A 4a9jC-4xzgA:
undetectable		 4a9jC-4xzgA:
26.09