SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4y0c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 4y0c CLP PROTEASE-RELATED
PROTEIN AT4G12060,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 LYS B 225
LEU B 229
GLU B 230
LEU B 202
 None
 0.77A 3h5gA-4y0cB:
undetectable
3h5gC-4y0cB:
undetectable		 3h5gA-4y0cB:
13.87
3h5gC-4y0cB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4y0c CLP PROTEASE-RELATED
PROTEIN AT4G12060,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU B 216
ILE B 204
LEU B 171
GLY B 125
ILE B 200
 None
 1.07A 6qxsB-4y0cB:
undetectable		 6qxsB-4y0cB:
20.71