SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4y1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		4 / 7 VAL A  51
TYR A  18
ILE A   7
ASP A  54
 None
 1.00A 2x45B-4y1gA:
undetectable		 2x45B-4y1gA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		4 / 7 VAL A  51
TYR A  18
ILE A   7
ASP A  54
 None
 1.02A 2x45C-4y1gA:
undetectable		 2x45C-4y1gA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		4 / 6 ASN A  40
SER A  41
ALA A  39
ASP A  54
 None
 1.28A 3aruA-4y1gA:
undetectable		 3aruA-4y1gA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		4 / 7 VAL A  51
TYR A  18
ILE A   7
ASP A  54
 None
 0.97A 3bu1A-4y1gA:
undetectable		 3bu1A-4y1gA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		5 / 12 TYR A  65
GLY A  36
ALA A  60
VAL A  53
ASN A  40
 None
 1.00A 3jb3A-4y1gA:
undetectable		 3jb3A-4y1gA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		4 / 4 ASP A 115
ASP A 116
GLY A  88
THR A 101
 None
 1.30A 3tl9B-4y1gA:
undetectable		 3tl9B-4y1gA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		5 / 12 ILE A 104
ILE A 110
ASP A 113
ILE A 112
ARG A 129
 CSO  A 105 ( 3.6A)
None
None
None
None
 1.13A 4iv0B-4y1gA:
2.8		 4iv0B-4y1gA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		4 / 7 ILE A 112
GLN A 109
PRO A 108
ILE A  70
 None
None
CSO  A 105 ( 4.4A)
None
 1.05A 4w5oA-4y1gA:
undetectable		 4w5oA-4y1gA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		5 / 12 ALA A  39
ALA A  28
ALA A  24
LEU A  69
THR A  52
 None
 1.22A 5tl8A-4y1gA:
undetectable		 5tl8A-4y1gA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4y1g UNCHARACTERIZED
PROTEIN SAV1875
(Staphylococcus
aureus) 		3 / 3 ASP A  98
ASN A 149
ASP A 147
 None
 0.89A 5vopB-4y1gA:
undetectable		 5vopB-4y1gA:
22.67