SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4y66'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 4y66 PUTATIVE TBPIP
FAMILY PROTEIN
(Giardia
intestinalis) 		4 / 4 GLN B 123
VAL B 120
GLU B 119
ILE B 117
 None
 1.32A 5jncA-4y66B:
undetectable		 5jncA-4y66B:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4y66 MND1
PUTATIVE TBPIP
FAMILY PROTEIN
(Giardia
intestinalis;
Giardia
intestinalis) 		4 / 6 ASP B 163
ARG A 154
ASN A 155
ASN B 160
 None
 1.15A 5l6eA-4y66B:
undetectable		 5l6eA-4y66B:
19.76