SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4y68'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU C 313
LEU C 122
ILE C 126
THR C 130
LEU C 163
 None
 0.99A 2bdmA-4y68C:
undetectable		 2bdmA-4y68C:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 GLY C 170
GLY C 171
SER C 135
SER C 236
HIS C  98
 None
 0.77A 4ey6A-4y68C:
undetectable		 4ey6A-4y68C:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU C 165
LEU C 180
ILE C 152
LEU C 153
LEU C 128
 None
 1.19A 4j24D-4y68C:
undetectable		 4j24D-4y68C:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_B_Z80B401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 9 ILE C 228
PHE C 245
THR C 234
ASN C 168
ASP C 164
 None
 1.17A 5lg3B-4y68C:
undetectable		 5lg3B-4y68C:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_C_Z80C401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 9 ILE C 228
PHE C 245
THR C 234
ASN C 168
ASP C 164
 None
 1.17A 5lg3C-4y68C:
undetectable		 5lg3C-4y68C:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 9 ILE C 228
PHE C 245
THR C 234
ASN C 168
ASP C 164
 None
 1.19A 5lg3D-4y68C:
undetectable		 5lg3D-4y68C:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ILE C 228
PHE C 245
THR C 234
ASN C 168
ASP C 164
 None
 1.22A 5lg3F-4y68C:
undetectable		 5lg3F-4y68C:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ILE C 296
PHE C 245
THR C 234
ASN C 168
ASP C 164
 None
 1.23A 5lg3F-4y68C:
undetectable		 5lg3F-4y68C:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ILE C 228
PHE C 245
THR C 234
ASN C 168
ASP C 164
 None
 1.20A 5lg3G-4y68C:
undetectable		 5lg3G-4y68C:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ILE C 296
PHE C 245
THR C 234
ASN C 168
ASP C 164
 None
 1.25A 5lg3G-4y68C:
undetectable		 5lg3G-4y68C:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ILE C 228
PHE C 245
THR C 234
ASN C 168
ASP C 164
 None
 1.19A 5lg3H-4y68C:
undetectable		 5lg3H-4y68C:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ILE C 228
PHE C 245
THR C 234
ASN C 168
ASP C 164
 None
 1.21A 5lg3J-4y68C:
undetectable		 5lg3J-4y68C:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU C  48
ILE C  47
SER C  83
GLY C  55
ILE C  66
 None
 1.08A 5m24A-4y68C:
undetectable		 5m24A-4y68C:
20.54