SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4y6t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4y6t COAT PROTEIN
(Tobacco
streak
virus) 		3 / 3 TRP A 200
VAL A 144
TRP A 107
 None
 0.85A 1c4dA-4y6tA:
undetectable
1c4dB-4y6tA:
undetectable		 1c4dA-4y6tA:
12.68
1c4dB-4y6tA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 4y6t COAT PROTEIN
(Tobacco
streak
virus) 		3 / 3 TYR A 178
MET A 153
LEU A 139
 None
 0.67A 3vw1D-4y6tA:
undetectable		 3vw1D-4y6tA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 4y6t COAT PROTEIN
(Tobacco
streak
virus) 		4 / 5 PHE A 183
PHE A 151
ILE A 141
GLY A 142
 None
 0.80A 4ejjC-4y6tA:
undetectable		 4ejjC-4y6tA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 4y6t COAT PROTEIN
(Tobacco
streak
virus) 		3 / 3 ARG A 207
ARG A 206
ASP A 113
 None
CME  A 201 ( 4.2A)
None
 0.79A 6d8pA-4y6tA:
undetectable		 6d8pA-4y6tA:
11.79